- 2025.12.01
Active ingredients Status Update Specialty trientine (dihydrochloride) Supply tension 28/11/2025 Cufence 200 mg, capsule desmopressin acetate trihydrate Stock shortage 28/11/2025 Octim 150 micrograms/dose, nasal spray solution cyamemazine Stock shortage 28/11/2025 Tercian 50 mg/5 mL, injectable solution in ampoule adrenaline Return to availability 28/11/2025 Epipen, injectable solution in a pre-filled pen phenylephrine Stock shortage 28/11/2025 Neosynephrine 10% Faure, eye drops in single-dose container methylphenidate (hydrochloride) Stock shortage 27/11/2025 Concerta LP, extended-release tablet bromfenac sodium sesquihydrate Supply tension 27/11/2025 Yellox 0.9 mg/mL, eye drops, solution methylphenidate (hydrochloride) Supply tension 27/11/2025 Biogaran Methylphenidate, extended-release tablet ritonavir Return to availability 27/11/2025 Ritonavir Arrow 100 mg, film-coated tablet betamethasone (dipropionate), betamethasone (sodium phosphate) Return to availability 27/11/2025 Diprostene, injectable suspension in pre-filled syringe tolvaptan Stock shortage 27/11/2025 Tolvaptan Teva 15 mg tablet + Tolvaptan Teva 45 mg tablet mesalazine Stock shortage 26/11/2025 Fivasa 400 mg, gastro-resistant coated tablet Normal human immunoglobulin (IgG) Supply tension 26/11/2025 Normal human immunoglobulin IV and SC (based on) dipotassium clorazepate Stock shortage 26/11/2025 Tranxene 20 mg/2 mL, lyophilisate and solution for parenteral use isoniazid, rifampicin Supply tension 26/11/2025 Rifinah 300 mg/150 mg, coated tablet isoniazid, pyrazinamid, rifampicin Supply tension 26/11/2025 Rifater, coated tablet rifampicin Supply tension 26/11/2025 Rifadine 300 mg, capsule rifampicin Return to availability 26/11/2025 Rifadine IV 600 mg, powder and solvent for solution for infusion iron (in the form of ferrous sulfate heptahydrate) Supply tension 24/11/2025 AP-HP Iron 2.5 mg infant capsule – rifamycin sodium Supply tension 24/11/2025 Rifamycin Chibret 1,000,000 IU per cent, eye drops solution - 2025.11.24
Active ingredients Status Update Specialty olanzapine (pamoate) monohydrate Supply tension 21/11/2025 Zypadhera, powder and solvent for extended-release suspension for injection risperidone Supply tension 21/11/2025 Risperidone 0.5 mg, orodispersible tablet risperidone Stock shortage 21/11/2025 Risperidone 4 mg orodispersible tablet risperidone Stock shortage 21/11/2025 Risperidone 3 mg orodispersible tablet risperidone Return to availability 21/11/2025 Risperidone 1 mg and 2 mg, orodispersible tablet chlorpromazine (hydrochloride) Stock shortage 20/11/2025 Largactil 100 mg, film-coated tablet phenylephrine Stock shortage 19/11/2025 Neosynephrine 10% Faure, eye drops in single-dose container phenylephrine Supply tension 19/11/2025 Neosynephrine 10% Faure, eye drops solution phenylephrine Supply tension 19/11/2025 Neosynephrine 5% Faure, eye drops solution methylphenidate (hydrochloride) Supply tension 19/11/2025 Methylphenidate EG LP, extended-release tablet ornidazole Stock shortage 18/11/2025 Tiberal 1 g, solution for injection for infusion colchicine, opium (powder), tiemonium (methyl sulfate) Supply tension 18/11/2025 Colchimax, breakable film-coated tablet, and Colchicine Opocalcium 1 mg, breakable tablet lenalidomide Stock shortage 18/11/2025 Lenalidomide Mylan, capsule adrenaline (tartrate) Return to availability 17/11/2025 Jext 300 micrograms, injectable solution in pre-filled pen - 2025.11.18
Active ingredients Status Update Specialty dopamine (hydrochloride) Supply tension 14/11/2025 Dopamine Viatris 40 mg/mL, solution for infusion dipotassium clorazepate Stock shortage 14/11/2025 Tranxene 20 mg/2 mL, lyophilisate and solution for parenteral use cyamemazine Stock shortage 14/11/2025 Tercian 50 mg/5 mL, injectable solution in ampoule temozolomide Return to availability 14/11/2025 Temodal 2.5 mg/mL, powder for solution for infusion propofol Return to availability 14/11/2025 Diprivan 20 mg/mL, injectable emulsion in pre-filled syringe propofol Return to availability 14/11/2025 Diprivan 10 mg/mL, injectable emulsion in pre-filled syringe megestrol (acetate) Stock shortage 13/11/2025 Megace 160 mg, tablet methylphenidate (hydrochloride) Supply tension 13/11/2025 Methylphenidate EG LP 18 mg and 36 mg, extended-release tablet fluorouracil Supply tension 13/11/2025 Fluorouracil Pfizer 50 mg/mL, solution for dilution for infusion – 20 mL and 100 mL vials valproic acid, sodium (valproate) Supply tension 13/11/2025 Micropakine L.P., extended-release granules in single-dose sachets tolvaptan Stock shortage 10/11/2025 Tolvaptan Biogaran 15 mg, tablet + Tolvaptan Biogaran 45 mg, tablet – tolvaptan Stock shortage 10/11/2025 Tolvaptan Teva 15 mg tablet + Tolvaptan Teva 45 mg tablet - 2025.11.10
Active ingredients Status Update Specialty diltiazem (hydrochloride) Supply tension 07/11/2025 Tildiem 25 mg, powder and solution for intravenous injection tolvaptan Supply tension 07/11/2025 Tolvaptan Biogaran 30 mg, tablet + Tolvaptan Biogaran 60 mg, tablet urokinase Return to availability 07/11/2025 Thérasolv 250,000 IU, powder for solution for injection/infusion diltiazem (hydrochloride) Marketing discontinuation 07/11/2025 Tildiem 100 mg, powder for solution for injection (IV) chlorpromazine (hydrochloride) Stock shortage 07/11/2025 Largactil 100 mg, film-coated tablet pertuzumab/trastuzumab Return to availability 07/11/2025 Phesgo 1200 mg/600 mg, solution for injection clomipramine (hydrochloride) Supply tension 06/11/2025 Clomipramine Viatris 25 mg, film-coated tablet ornidazole Return to availability 05/11/2025 Tiberal 500 mg, solution for infusion cyamemazine Stock shortage 03/11/2025 Tercian 50 mg/5 mL, injectable solution in ampoule - 2025.11.03
Active ingredients Statut Update Specialty caffeine, opium (dry extract of), paracetamol Supply tension 31/10/2025 Lamaline, suppository mesalazine Supply tension 31/10/2025 Pentasa 1 g and 2 g, granules in sachets, and Pentasa 1 g, suppositories demeclocycline hydrochloride Stock shortage 31/10/2025 Alkonatrem 150 mg, capsule Immunoglobuline humaine rabique Marketing discontinuation 31/10/2025 Imogam Rage 150 UI/mL, solution injectable clarithromycin Return to availability 31/10/2025 Clarithromycin, 250 and 500 mg, modified-release film-coated tablet and film-coated tablet clarithromycin Return to availability 31/10/2025 Clarithromycin Arrow 25 mg/mL, granules for oral suspension clarithromycin Return to availability 31/10/2025 Clarithromycin 50 mg/mL, granules for oral suspension Return to availability 31/10/2025 Copper 6 mg/1 mL Histidine 117.20 mg/3 mL AP-HP, injectable solution, CIPH code 77772737 chlorpromazine (hydrochloride) Stock shortage 31/10/2025 Largactil 100 mg, film-coated tablet acide ascorbique Supply tension 10/30/2025 Laroscorbine 1 g/5 ml, solution injectable I.V. en ampoule tobramycin Supply tension 10/30/2025 Tobi Podhaler 28 mg, powder for inhalation in capsules cytarabine Return to availability 10/30/2025 Cytarabine Sandoz 100 mg/mL, solution for injection – 1 glass vial(s) of 50 mL varenicline (tartrate) Supply tension 10/30/2025 Champix 0.5 mg and 1 mg, film-coated tablet fluorouracil Supply tension 29/10/2025 Fluorouracil Accord 50 mg/mL, solution for dilution for infusion, 5 mL and 100 mL vials methylprednisolone (sodium hydrogen succinate) Return to availability 29/10/2025 Methylprednisolone Hikma 40 mg, powder for solution for injection lithium (carbonate) Supply tension 29/10/2025 Teralithe 250 mg, breakable tablet lithium (carbonate) Supply tension 29/10/2025 Teralithe LP 400 mg, extended-release breakable tablet bromfenac sodium sesquihydrate Supply tension 28/10/2025 Yellox 0.9 mg/mL, eye drops, solution epoetin beta Supply tension 28/10/2025 NeoRecormon range, injectable solution in pre-filled syringe temozolomide Supply tension 28/10/2025 Temodal 2.5 mg/mL, powder for solution for infusion methylprednisolone (sodium hydrogen succinate) Supply tension 28/10/2025 Methylprednisolone Hikma 500 mg, powder for solution for injection tolvaptan Supply tension 27/10/2025 Jinarc 15 mg tablet + Jinarc 45 mg tablet tolvaptan Stock shortage 27/10/2025 Tolvaptan Teva 15 mg tablet + Tolvaptan Teva 45 mg tablet cyanocobalamin Supply tension 27/10/2025 Vitamin B12 Delagrange 1000 micrograms/2 mL, injectable (IM) and oral solution tolvaptan Stock shortage 27/10/2025 Tolvaptan Biogaran 15 mg, tablet + Tolvaptan Biogaran 45 mg, tablet - 2025.10.27
Active ingredients Statut Update Specialty Synthetic vitamin A concentrate, oily form Marketing discontinuation 24/10/2025 Vitamin A Dulcis 25,000 I.U. per 100 g, ophthalmic ointment bumetanide Return to availability 24/10/2025 Burinex 2 mg/4 ml IV, solution for injection in ampoule methylphenidate hydrochloride Stock shortage 23/10/2025 Concerta LP, extendedrelease tablet paclitaxel Supply tension 23/10/2025 Paclitaxel AHCL 6 mg/ml, dilutable solution for infusion 50 ml and 100 ml vials lithium (carbonate of) Supply tension 23/10/2025 Teralithe 250 mg, scored tablet venlafaxine Supply tension 23/10/2025 Specialties based on Venlafaxine LP 37.5 mg and LP 75 mg sustainedrelease capsules carbamazepine Return to availability 23/10/2025 Carbamazepine Viatris L.P. 200 mg, scored sustainedrelease tablet carbamazepine Return to availability 23/10/2025 Carbamazepine Viatris L.P. 400 mg, scored sustainedrelease tablet chlorpromazine (hydrochloride) Stock shortage 22/10/2025 Largactil 100 mg, scored filmcoated tablet fluorouracil Supply tension 21/10/2025 Fluorouracil Accord 50 mg/ml, solution for diluted infusion, 5 ml and 100 ml bottles fluorouracil Stock shortage 21/10/2025 Fluorouracil Pfizer 50 mg/ml, dilutable solution for infusion 20 ml and 100 ml bottle mitomycin Supply tension 21/10/2025 Mitomycin Accord 20 mg, powder for solution for injection / infusion or intravesical use varenicline (tartrate) Stock shortage 20/10/2025 Champix 0.5 mg and 1 mg, filmcoated tablet liothyronine sodium Supply tension 20/10/2025 Cynomel 0.025 mg, scored tablet emtricitabine/tenofovir disoproxil Return to availability 20/10/2025 Speciality based on emtricitabine/tenofovir disoproxil 200 mg/245 mg, filmcoated tablet - 2025.10.20
Active ingredients Statut Update Specialty digoxine Supply tension 10/17/2025 Digoxine Nativelle 5 µg/0.1 ml, solution buvable en gouttes pyrantel (embonate of) Supply tension 10/17/2025 Combantrin 125 mg, tablet rifamycin sodium Supply tension 10/17/2025 Rifamycin Chibret 1000 000 IU per cent, eye drops solution risperidone Supply tension 10/17/2025 Risperidone 0.5 mg, 1 mg, 2 mg and 3 mg orodispersible tablet risperidone Out of stock 10/17/2025 Risperidone 4 mg Orodispersible tablet olipudase alfa Supply tension 15/10/2025 Xenpozyme 20 mg, powder for solution to be diluted for infusion pertuzumab/trastuzumab Out of stock 15/10/2025 Phesgo 1200 mg/600 mg, solution injectable risperidone Out of stock 15/10/2025 RisperdalConsta L.P. 37.5 mg/2 ml, powder and solvent for prolongedrelease suspension for injection in prefilled syringe risperidone Supply tension 15/10/2025 RisperdalConsta L.P. 50 mg/2 ml and 25 mg/2 ml, powder and solvent for prolongedrelease suspension for injection in prefilled syringe risperidone Out of stock 15/10/2025 Risperidone L.P. 25 mg/2 ml, 37.5 mg/2 ml and 50 mg/2 ml, powder and solvent for prolongedrelease suspension for injection in prefilled syringe lenalidomide Out of stock 15/10/2025 Lenalidomide Mylan, capsule dipyridamole Supply tension 15/10/2025 Persantine 10 mg/2 mL, solution injectable, ampoule chlorpromazine (hydrochloride) Supply tension 13/10/2025 Largactil 25 mg, filmcoated tablet VaricellaZoster Virus (VZV) glycoprotein E antigen (recombinant, adjuvanted) (mammalian/hamster/CHO cells) Supply tension 13/10/2025 Shingrix, powder and suspension for injectable suspension. Varicella zoster vaccine (recombinant, adjuvanted) esketamine (hydrochloride) Return to availability 13/10/2025 Eskesia 5 mg/mL, solution for injection/infusion 10 glass ampoule(s) of 5 ml - 2025.10.13
Active ingredients Statut Update Specialty betamethasone (dipropionate), betamethasone (sodium phosphate) Supply tension 09/10/2025 Diprostene, suspension for injection in pre-filled syringe pancreas powder Supply tension 08/10/2025 Eurobiol 40 000 U, gastroresistant capsule liothyronine sodium Supply tension 07/10/2025 Cynomel 0.025 mg, scored tablet furosemide Marketing discontinuation 06/10/2025 Lasilix Retard 60 mg, capsule peginterferon alfa-2a Return to availability 06/10/2025 Pegasys 90 micrograms, 135 micrograms and 180 micrograms solution for injection in prefilled syringes - 2025.10.05
Active ingredients Statut Update Specialty tranexamic acid Return to availability 03/10/2025 Exacyl 500 mg, film-coated tablet chlorpromazine (hydrochloride) Out of stock 03/10/2025 Largactil 100 mg, scored film-coated tablet praziquantel Out of stock 02/10/2025 Biltricide 600 mg, film-coated quadrisectible tablet fluorouracil Out of stock 02/10/2025 Fluorouracil Pfizer 50 mg/ml, dilutable solution for infusion20 ml and 100 ml bottle atropine (sulfate) Supply tension 02/10/2025 Atropine 0.3%, eye drops Immunoglobulin normal human (IgG) Supply tension 01/10/2025 Immunoglobulin normal human IV and SC (based on) propofol Out of stock 29/09/2025 Diprivan 10 mg/mL, emulsion for injection in pre-filled syringe propofol Supply tension 29/09/2025 Diprivan 20 mg/mL, emulsion for injection in pre-filled syringe - 2025.09.28
Active ingredients Statut Update Specialty demeclocycline hydrochloride Out of stock 26/09/2025 Alkonatrem 150 mg, capsule lenalidomide Out of stock 26/09/2025 Lenalidomide Mylan, capsule methylphenidate hydrochloride Supply tension 24/09/2025 Methylphenidate Biogaran, extendedrelease tablet cyclophosphamide Supply tension 24/09/2025 Endoxan 50 mg, coated tablet adrenaline Supply tension 24/09/2025 Epipen, solution for injection in prefilled pen methotrexate Return to availability 23/09/2025 Viatris methotrexate 100 mg/ml, solution for injection (10 ml and 50 ml vials) tiapride (chlorhydrate de) Return to availability 23/09/2025 Tiapridal 100 mg/2 ml, solution injectable sertraline (hydrochloride) Return to availability 23/09/2025 Sertraline 25 mg and 50 mg, capsule sugammadex sodique Return to availability 23/09/2025 Sugammadex 100 mg/mL, solution injectable flacons de 5 ml Immunoglobulin normal human (IgG) Supply tension 22/09/2025 Immunoglobulin normal human IV and SC (based on) fluoroestradiol (18F) Return to availability 22/09/2025 Estrotep 500 MBq/mL, solution injectable potassium (bicarbonate) /potassium (citrate) Out of stock 22/09/2025 Sibnayal 8 mEq, sustainedrelease granules