Active ingredients	Message type	Date of the last message	Type of reason
Moxifloxacin hydrochloride (Ph.Eur.) ((with details of water content (1:x)))	Initial notification	16.05.2025	Other
Levomethadone hydrochloride	Change notification	16.05.2025	Other
Sodium mucophenolate	Change notification	16.05.2025	Other
Hydromorphone hydrochloride	Change notification	16.05.2025	Other
Arsenic(III) oxide	Initial notification	16.05.2025	Other
Sodium (methylprednisolone-21-succinate)	Initial notification	16.05.2025	Other
Moxifloxacin hydrochloride (Ph.Eur.) ((with details of water content (1:x)))	Change notification	15.05.2025	Production problem
Insulin aspart	Initial notification	15.05.2025	Other
Salbutamol sulfate	Change notification	15.05.2025	Other
Methylphenidate hydrochloride	Change notification	15.05.2025	Other
Aprepitant	Change notification	15.05.2025	Other
Quetiapine fumarate (Ph.Eur.)	Change notification	15.05.2025	Other
Sertraline hydrochloride	Initial notification	15.05.2025	Production problem
Flupentixol decanoate	Change notification	15.05.2025	Production problem
Aprepitant	Initial notification	14.05.2025	Other
Epinephrine/adrenaline	Change notification	14.05.2025	Production problem
Erythromycin	Change notification	14.05.2025	Other
Trazodone hydrochloride	Initial notification	14.05.2025	Other
Tenofovir disoproxil	Change notification	14.05.2025	Other
Ezetimibe; Simvastatin	Initial notification	14.05.2025	Production problem
Methylphenidate hydrochloride	Initial notification	14.05.2025	Production problem
Zoledronic acid monohydrate	Change notification	14.05.2025	Production problem
Cyclophosphamide monohydrate	Change notification	14.05.2025	Other
Zoledronic acid monohydrate	Change notification	14.05.2025	Production problem
Metformin hydrochloride; sitagliptin hydrochloride monohydrate	Change notification	14.05.2025	Other
Morphine hemisulfate 2,5-hydrate	Initial notification	13.05.2025	Other
Sodium (methylprednisolone-21-succinate)	Initial notification	13.05.2025	Other
Prednisolone	Initial notification	13.05.2025	Production problem
Lorazepam	Initial notification	13.05.2025	Other
Mometasone furoate (Ph.Eur.)	Change notification	12.05.2025	Production problem
Tropicamide	Change notification	12.05.2025	Production problem
Rizatriptan benzoate	Change notification	12.05.2025	Production problem
Ezetimibe	Change notification	12.05.2025	Production problem
Atomoxetine hydrochloride	Change notification	12.05.2025	Production problem
Cyclopentolate hydrochloride	Change notification	12.05.2025	Production problem
Atorvastatin calcium trihydrate (Ph.Eur.)	Change notification	12.05.2025	Other
Ciclopirox-Olamin	Change notification	12.05.2025	Other
Mometasone furoate (Ph.Eur.)	Change notification	12.05.2025	Other

Ingredients	Status	Update	Specialty
Immunoglobulin normal human (IgG)	Supply tension	15/05/2025	Immunoglobulin normal human IV and SC (based on) –
methylphenidate (hydrochloride)	Available for use	15/05/2025	Methylphenidate Arrow LP, sustained-release capsule –
disopyramide (phosphate)	Out of stock	15/05/2025	Rythmodan 250 mg sustained-release, coated tablet –
levodopa – carbidopa	Available for use	15/05/2025	Sinemet 250 mg/25 mg, scored tablet –
levomepromazine	Available for use	15/05/2025	Nozinan 100 mg, scored film-coated tablet –
peginterferon alfa-2a	Supply tension	14/05/2025	Pegasys 90 micrograms, 135 micrograms and 180 micrograms solution for injection in pre-filled syringe –
venlafaxine	Supply tension	13/05/2025	Venlafaxine Viatris 50 mg, film-coated tablet –
liothyronine sodium	Supply tension	13/05/2025	Cynomel 0.025 mg, comprimé sécable-
methylphenidate (hydrochloride)	Out of stock	13/05/2025	Methylphenidate EG LP 18 mg and 54 mg, extended-release tablet –
(tranexamic acid	Supply tension	13/05/2025	Exacyl 500 mg, film-coated tablet – )
colchicine, opium (powder), tiemonium (metilsulfate)	Supply tension	13/05/2025	Colchimax, scored film-coated tablet and Colchicine Opocalcium 1 mg, scored tablet –
hydroxocobalamin	Supply tension	12/05/2025	Cyanokit 5 g, powder for solution for infusion –
amiodarone	Supply tension	12/05/2025	Cordarone 150 mg/3 ml, solution for injection in ampoule (IV) –

Active ingredients	Dosage form	Quantity of active ingredients	Shortage status	Availability	Reason	Last updated
fentanyl	Drug delivery system, transdermal	4.2 mg	Discontinued	Unavailable	Manufacturing	16/05/2025
fentanyl	Drug delivery system, transdermal	8.4 mg	Discontinued	Unavailable	Manufacturing	16/05/2025
fentanyl	Drug delivery system, transdermal	12.6 mg	Discontinued	Unavailable	Manufacturing	16/05/2025
fentanyl	Drug delivery system, transdermal	16.8 mg	Discontinued	Unavailable	Manufacturing	16/05/2025
fentanyl	Drug delivery system, transdermal	2.1 mg	Discontinued	Unavailable	Manufacturing	16/05/2025
calcitonin salmon	Injection, solution	100 IU/mL	Current	Limited Availability	Commercial Changes / Commercial viability	16/05/2025
furosemide	Injection, solution	20 mg	Resolved	Available	Manufacturing	16/05/2025
silver sulfadiazine	Cream	10 mg/g	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	16/05/2025
silver sulfadiazine	Cream	10 mg/g	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	16/05/2025
fentanyl	Drug delivery system, transdermal	5.1 mg	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	16/05/2025
fentanyl	Drug delivery system, transdermal	7.65 mg	Discontinued	Unavailable	Commercial Changes / Commercial viability	16/05/2025
fentanyl	Drug delivery system, transdermal	1.28 mg	Discontinued	Unavailable	Commercial Changes / Commercial viability	16/05/2025
fentanyl	Drug delivery system, transdermal	10.2 mg	Discontinued	Unavailable	Commercial Changes / Commercial viability	16/05/2025
fentanyl	Drug delivery system, transdermal	2.55 mg	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	16/05/2025
carboplatin	Injection, solution	450 mg	Anticipated	Available	Manufacturing	16/05/2025
dulaglutide	Injection, solution	1.5 mg	Current	Limited Availability	Manufacturing	16/05/2025
busulfan	Injection, concentrated	60 mg	Current	Limited Availability	Manufacturing	16/05/2025
isavuconazonium sulfate	Capsule, hard	186.3 mg	Resolved	Available	Manufacturing	16/05/2025
buprenorphine hydrochloride	Tablet, uncoated	.216 mg	Anticipated	Available	Manufacturing	16/05/2025
lidocaine hydrochloride	Injection, solution	10 mg/mL	Current	Unavailable	Manufacturing	16/05/2025
paclitaxel	Injection, concentrated	6 mg/mL	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	16/05/2025
iopromide	Injection, solution	498.72 mg/mL	Resolved	Available	Manufacturing	16/05/2025
voriconazole	Tablet, film coated	50 mg	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	16/05/2025
sertraline hydrochloride	Tablet, film coated	112 mg	Anticipated	Available	Manufacturing	16/05/2025
ceftazidime pentahydrate	Injection, powder for	2.328 g	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	15/05/2025
sumatriptan succinate	Tablet, film coated	140 mg	Resolved	Available	Manufacturing	15/05/2025
bethanechol chloride	Tablet, uncoated	10 mg	Anticipated	Available	Manufacturing	15/05/2025
galantamine hydrobromide	Capsule, modified release	20.512 mg	Current	Limited Availability	Manufacturing	15/05/2025
methylphenidate hydrochloride	Capsule, modified release	10 mg	Current	Limited Availability	Manufacturing	15/05/2025
valsartan~hydrochlorothiazide	Tablet, film coated	160 mg~12.5 mg	Current	Limited Availability	Manufacturing	15/05/2025
amlodipine besilate~atorvastatin calcium trihydrate	Tablet, film coated	6.94 mg~43.376 mg	Anticipated	Available	Manufacturing	15/05/2025
rosuvastatin calcium~ezetimibe	Tablet~Tablet, film coated	10.396 mg~10 mg	Resolved	Available	Manufacturing	15/05/2025
imatinib mesilate	Capsule, hard	119.47 mg	Resolved	Available	Manufacturing	15/05/2025
mercaptopurine monohydrate	Tablet	50 mg	Current	Limited Availability	Manufacturing	15/05/2025
topotecan hydrochloride	Injection, concentrated	4.346 mg	Resolved	Available	Manufacturing	15/05/2025
irinotecan hydrochloride trihydrate	Injection, concentrated	500 mg	Resolved	Available	Manufacturing	15/05/2025
metoprolol tartrate	Tablet, uncoated	50 mg	Current	Limited Availability	Manufacturing	15/05/2025
foscarnet sodium	Injection, solution	24 mg/mL	Current	Limited Availability	Manufacturing	15/05/2025
bleomycin sulfate	Injection, powder for	15000 IU	Anticipated	Available	Manufacturing	15/05/2025
trandolapril	Capsule, hard	2 mg	Anticipated	Available	Manufacturing	15/05/2025
losartan potassium	Tablet, film coated	50 mg	Current	Limited Availability	Unexpected increase in consumer demand	15/05/2025
voriconazole	Injection, powder for	200 mg	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	15/05/2025
sertraline hydrochloride	Tablet, film coated	56 mg	Anticipated	Available	Manufacturing	15/05/2025
Mumps virus~Rubella virus~Measles virus	Injection, powder for	5000 CCID50~1000 CCID50~1000 CCID50	Anticipated	Available	Unexpected increase in consumer demand	15/05/2025
fentanyl	Drug delivery system, transdermal	16.8 mg	Resolved	Available	Unexpected increase in demand due to other sponsors unable to supply	14/05/2025
honey bee venom	Injection, powder for	550 microgram	Current	Limited Availability	Manufacturing	14/05/2025
perindopril erbumine	Tablet	8 mg	Current	Limited Availability	Manufacturing	14/05/2025
Paper wasp venom	Injection, powder for	550 microgram	Current	Unavailable	Manufacturing	14/05/2025
lansoprazole	Tablet, orally disintegrating	15 mg	Current	Limited Availability	Manufacturing	14/05/2025
celecoxib	Capsule, hard	200 mg	Current	Limited Availability	Manufacturing	14/05/2025
entecavir	Tablet, film coated	.5 mg	Current	Unavailable	Manufacturing	14/05/2025
cisatracurium besilate	Injection, solution	14.07 mg	Current	Limited Availability	Manufacturing	14/05/2025
procarbazine hydrochloride	Capsule, hard	58.3 mg	Resolved	Available	Manufacturing	14/05/2025
atomoxetine hydrochloride	Capsule, hard	91.44 mg	Resolved	Available	Unexpected increase in demand due to other sponsors unable to supply	14/05/2025
olanzapine	Tablet, uncoated	5 mg	Resolved	Available	Manufacturing	14/05/2025
dosulepin hydrochloride	Capsule, hard	25 mg	Resolved	Available	Manufacturing	14/05/2025
methylphenidate hydrochloride	Capsule, hard	40 mg	Current	Limited Availability	Unexpected increase in demand due to other sponsors unable to supply	14/05/2025
methylphenidate hydrochloride	Capsule, hard	30 mg	Anticipated	Available	Unexpected increase in demand due to other sponsors unable to supply	14/05/2025
methylphenidate hydrochloride	Capsule, hard	10 mg	Anticipated	Available	Unexpected increase in demand due to other sponsors unable to supply	14/05/2025
fentanyl citrate	Injection, solution	785 microgram	Current	Limited Availability	Manufacturing	14/05/2025
tamoxifen citrate	Tablet, uncoated	15.2 mg	Current	Unavailable	Manufacturing	14/05/2025
tamoxifen citrate	Tablet, uncoated	30.4 mg	Current	Limited Availability	Manufacturing	14/05/2025
gemfibrozil	Tablet, film coated	600 mg	Current	Unavailable	Manufacturing	14/05/2025
mirtazapine	Tablet, film coated	30 mg	Resolved	Available	Manufacturing	14/05/2025
trimethoprim~sulfamethoxazole	Tablet	160 mg~800 mg	Resolved	Available	Unexpected increase in consumer demand	13/05/2025
pramipexole dihydrochloride monohydrate	Tablet	.25 mg	Anticipated	Available	Manufacturing	13/05/2025
phenobarbital sodium	Injection, solution	219 mg/mL	Anticipated	Available	Manufacturing	13/05/2025
galantamine hydrobromide	Capsule, modified release	10.252 mg	Current	Unavailable	Manufacturing	13/05/2025
galantamine hydrobromide	Capsule, modified release	20.504 mg	Current	Unavailable	Manufacturing	13/05/2025
ondansetron	Tablet, orally disintegrating	8 mg	Current	Unavailable	Manufacturing	13/05/2025
raloxifene hydrochloride	Tablet, film coated	60 mg	Resolved	Available	Unexpected increase in consumer demand	13/05/2025
dutasteride	Capsule, soft	500 microgram	Current	Limited Availability	Manufacturing	13/05/2025
capecitabine	Tablet, film coated	500 mg	Current	Limited Availability	Unexpected increase in consumer demand	13/05/2025
methotrexate	Injection, solution	100 mg/mL	Current	Unavailable	Manufacturing	13/05/2025
pramipexole dihydrochloride monohydrate	Tablet, modified release	.375 mg	Current	Limited Availability	Manufacturing	13/05/2025
linezolid	Tablet, film coated	600 mg	Current	Unavailable	Manufacturing	13/05/2025
irbesartan	Tablet, film coated	300 mg	Anticipated	Available	Manufacturing	13/05/2025
irbesartan	Tablet, film coated	150 mg	Anticipated	Available	Manufacturing	13/05/2025
nizatidine	Capsule, hard	150 mg	Current	Unavailable	Manufacturing	13/05/2025
moxonidine	Tablet, film coated	200 microgram	Current	Limited Availability	Manufacturing	13/05/2025
ropinirole hydrochloride	Tablet, film coated	.57 mg	Resolved	Available	Manufacturing	13/05/2025
risperidone	Tablet, film coated	3 mg	Resolved	Available	Transport / Logistic issues / Storage capacity issues	13/05/2025
atorvastatin calcium trihydrate~ezetimibe	Tablet, film coated	41.363 mg~10 mg	Current	Unavailable	Manufacturing	13/05/2025
suxamethonium chloride dihydrate	Injection, solution	100 mg	Anticipated	Available	Manufacturing	13/05/2025
methotrexate	Tablet	10 mg	Resolved	Available	Manufacturing	13/05/2025
azithromycin dihydrate	Tablet, film coated	524 mg	Current	Unavailable	Unexpected increase in consumer demand	13/05/2025
rivaroxaban	Tablet, film coated	20 mg	Current	Limited Availability	Manufacturing	13/05/2025
metoclopramide hydrochloride monohydrate	Injection, solution	10.54 mg	Anticipated	Available	Unexpected increase in consumer demand	13/05/2025
midazolam	Injection, solution	5 mg/mL	Current	Limited Availability	Unexpected increase in consumer demand	13/05/2025
Teriparatide	Injection, solution	250 microgram	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	13/05/2025
metformin hydrochloride	Tablet, film coated	1000 mg	Current	Limited Availability	Unexpected increase in demand due to other sponsors unable to supply	13/05/2025
Peginterferon alfa2a	Injection, solution	180 microgram	Current	Limited Availability	Unexpected increase in consumer demand	13/05/2025
heparin sodium	Injection, solution	5000 IU/mL	Resolved	Available	Unexpected increase in consumer demand	12/05/2025
exemestane	Tablet, film coated	25 mg	Current	Unavailable	Manufacturing	12/05/2025
aripiprazole	Tablet, uncoated	10 mg	Current	Limited Availability	Manufacturing	12/05/2025
sulfamethoxazole~trimethoprim	Tablet, uncoated	800 mg~160 mg	Current	Limited Availability	Manufacturing	12/05/2025
montelukast sodium	Tablet, chewable	4.16 mg	Anticipated	Available	Manufacturing	12/05/2025
quetiapine fumarate	Tablet, modified release	57.565 mg	Current	Unavailable	Unexpected increase in consumer demand	12/05/2025
zolmitriptan	Tablet, film coated	2.5 mg	Current	Unavailable	Manufacturing	12/05/2025
zolmitriptan	Tablet, film coated	2.5 mg	Current	Unavailable	Manufacturing	12/05/2025
adrenaline (epinephrine) acid tartrate	Injection, solution	182 microgram/mL	Current	Unavailable	Manufacturing	12/05/2025
estradiol~dydrogesterone	Tablet, film coated	1 mg~10 mg	Resolved	Available	Manufacturing	12/05/2025
ezetimibe	Tablet, uncoated	10 mg	Resolved	Available	Manufacturing	12/05/2025
olmesartan medoxomil~hydrochlorothiazide	Tablet	40 mg~25 mg	Resolved	Available	Manufacturing	12/05/2025
acamprosate calcium	Tablet, enteric coated	333 mg	Current	Limited Availability	Manufacturing	12/05/2025
avibactam sodium~ceftazidime pentahydrate	Injection, powder for	543.5 mg~2329.7 mg	Current	Limited Availability	Unexpected increase in consumer demand	12/05/2025
sitagliptin hydrochloride monohydrate	Tablet, film coated	54.5 mg	Resolved	Available	Manufacturing	12/05/2025

Generic Name	Shortage Status	Revision Date
23.4% Sodium Chloride Injection	Resolved Shortages	18-May-25
Bacteriostatic 0.9% Sodium Chloride Vials	Resolved Shortages	18-May-25
Etomidate Injection	Current Shortages	18-May-25
Furosemide Injection	Current Shortages	18-May-25
Hydrocodone and Acetaminophen Tablets	Current Shortages	18-May-25
Hydromorphone Immediate-Release Oral Presentations	Current Shortages	18-May-25
Irbesartan Tablets	Current Shortages	18-May-25
Lidocaine with Epinephrine Injection	Current Shortages	18-May-25
Magnesium Sulfate Injection	Current Shortages	18-May-25
Mesna Injection	Current Shortages	18-May-25
Methylprednisolone Sodium Succinate Injection	Current Shortages	18-May-25
Metoprolol Injection	Current Shortages	18-May-25
Minoxidil 2.5 mg Tablets	Current Shortages	18-May-25
Nalbuphine Injection	Current Shortages	18-May-25
Oxycodone Hydrochloride and Acetaminophen Tablets	Current Shortages	18-May-25
Propranolol Hydrochloride Injection	Current Shortages	18-May-25
Sterile Water for Injection – Small Volume Vials	Resolved Shortages	18-May-25
Acetaminophen Injection	Current Shortages	16-May-25
Acetylcysteine Oral and Inhalation Solution	Current Shortages	16-May-25
Amiodarone Injection	Current Shortages	16-May-25
Calcitriol Oral Solution	Current Shortages	16-May-25
Dexmethylphenidate Extended Release Capsules	Current Shortages	16-May-25
Disulfiram Tablets	Resolved Shortages	16-May-25
Dorzolamide Ophthalmic Solution	Current Shortages	16-May-25
Hydrocortisone Sodium Succinate Injection	Current Shortages	16-May-25
Hydroxyzine Pamoate Oral Capsules	Current Shortages	16-May-25
Imatinib Mesylate Tablets	Current Shortages	16-May-25
Isoniazid Tablets	Resolved Shortages	16-May-25
Lanthanum Carbonate Oral Presentations	Current Shortages	16-May-25
Lenalidomide Capsules	Current Shortages	16-May-25
Morphine Injection	Current Shortages	16-May-25
Morphine Oral Solution	Current Shortages	16-May-25
Paclitaxel Injection	Current Shortages	16-May-25
Propranolol Hydrochloride Oral Solution	Current Shortages	16-May-25
Remifentanil Injection	Current Shortages	16-May-25
Azathioprine Sodium Injection	Current Shortages	15-May-25
Cidofovir Injection	Current Shortages	15-May-25
Dexamethasone Sodium Phosphate Injection	Current Shortages	15-May-25
Doxorubicin Injection	Current Shortages	15-May-25
Erythromycin Lactobionate Injection	Current Shortages	15-May-25
Esmolol Injection	Current Shortages	15-May-25
Heparin Sodium Premixed Bags	Current Shortages	15-May-25
Hydromorphone Hydrochloride Injection	Current Shortages	15-May-25
Lanreotide Acetate Injection	Current Shortages	15-May-25
Adenosine Injection	Current Shortages	14-May-25
Aminocaproic Acid Injection	Current Shortages	14-May-25
Amphetamine Extended-Release Oral Presentations	Current Shortages	14-May-25
Bupivacaine Injection	Current Shortages	14-May-25
Chlorothiazide Sodium Injection	Current Shortages	14-May-25
Cisplatin Injection	Current Shortages	14-May-25
Diphenhydramine Injection	Resolved Shortages	14-May-25
Methylphenidate Extended Release Oral Presentations	Current Shortages	14-May-25
Methylphenidate Immediate-Release Tablets	Current Shortages	14-May-25
Anticoagulant Citrate Dextrose Formula A (ACD-A)	Resolved Shortages	13-May-25
Pegfilgrastim-cbqv Injection	Resolved Shortages	13-May-25
Heparin Injection	Current Shortages	12-May-25
Insulin Glargine Injection (Recombinant)	Current Shortages	12-May-25
Propofol Emulsion Injection	Current Shortages	12-May-25

海外医薬品の不足情報・医薬政策情報等をデイリーで発信中

国内不足状況

諸外国不足状況

New

May 14, 2025

Updated

May 16, 2025

May 15, 2025

May 14, 2025

May 12, 2025

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