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  • 2025.12.22 [ ドイツ ]
    BfArMボトルネック・レポート（2025年12月15日～12月21日）
    Active ingredients
    Message type
    		Date of last messageType of reasonAM designation
    AprepitantChange notification19.12.2025OtherEMEND 125 mg powder for oral suspension – OPXXXXmg
    ErythromycinInitial report19.12.2025Production problemAknemycin solution
    Fibrinogen, humanChange notification19.12.2025Production problemHaemocomplettan P 1g
    Fibrinogen, humanChange notification19.12.2025Production problemHaemocomplettan P 2g
    Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y)Change notification19.12.2025OtherFerrlecit 62.5 mg
    Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y)Change notification19.12.2025OtherFerrlecit 40 mg
    PosaconazoleChange notification19.12.2025Production problemNoxafil
    Esomeprazole hemimagnesiumChange notification19.12.2025Production problemESOMEPRAZOLE BASICS 40 mg gastro-resistant hard capsules
    Candesartan cilexetilChange notification19.12.2025OtherCANDESARTAN BASICS 32 mg tablets
    Candesartan cilexetilChange notification19.12.2025OtherCANDESARTAN BASICS 16 mg tablets
    Candesartan cilexetilChange notification19.12.2025OtherCANDESARTAN BASICS 8 mg tablets
    Candesartan cilexetilChange notification19.12.2025OtherCANDESARTAN BASICS 4 mg tablets
    Atorvastatin calcium trihydrate (Ph.Eur.)Change notification19.12.2025OtherATORVASTATIN BASICS 80 mg film-coated tablets
    Atorvastatin calcium trihydrate (Ph.Eur.)Change notification19.12.2025OtherATORVASTATIN BASICS 30 mg film-coated tablets
    Atorvastatin calcium trihydrate (Ph.Eur.)Change notification19.12.2025OtherATORVASTATIN BASICS 20 mg film-coated tablets
    Atorvastatin calcium trihydrate (Ph.Eur.)Change notification19.12.2025OtherATORVASTATIN BASICS 10 mg film-coated tablets
    Ciprofloxacin hydrochloride monohydrateChange notification19.12.2025OtherCIPRO BASICS 750 mg film-coated tablets
    Ciprofloxacin hydrochloride monohydrateChange notification19.12.2025OtherCIPRO BASICS 250 mg film-coated tablets
    Ezetimibe; simvastatinChange notification19.12.2025Production problemEZETIMIB/SIMVA BASICS 10 mg/80 mg tablets
    Ezetimibe; simvastatinChange notification19.12.2025Production problemEZETIMIB/SIMVA BASICS 10 mg/40 mg tablets
    Ezetimibe; simvastatinChange notification19.12.2025Production problemEZETIMIB/SIMVA BASICS 10 mg/20 mg tablets
    Ezetimibe; simvastatinChange notification19.12.2025Production problemEZETIMIBE/SIMVA BASICS 10 mg/10 mg tablets
    Esomeprazole hemimagnesiumChange notification19.12.2025Production problemESOMEPRAZOLE BASICS 20 mg gastro-resistant hard capsules
    Betamethasone acetate (Ph.Eur.); Betamethasone dihydrogen phosphate disodium (Ph.Eur.)Initial report19.12.2025OtherCelestan Depot
    MesalazineChange notification19.12.2025OtherClaversal 500 mg tablets
    Terazosin hydrochloride dihydrateChange notification19.12.2025OtherHeitrin 2 mg
    Proxymetacaine hydrochlorideChange notification19.12.2025Production problemProparacaine-POS 0.5%
    Gentamicin sulfateChange notification19.12.2025Production problemGentamicin POS
    Phenylephrine hydrochlorideChange notification19.12.2025Production problemNeosynephrine-POS 10%
    Epoetin thetaInitial report18.12.2025Production problemEporatio 4000 IU/0.5 ml injection solution in pre-filled syringe – OP (6×0.5 ml)
    EtanerceptInitial report18.12.2025OtherNepexto 50 mg solution for injection in a pre-filled syringe
    EtanerceptInitial report18.12.2025OtherNepexto 50 mg solution for injection in a pre-filled syringe
    EtanerceptInitial report18.12.2025OtherNepexto 50 mg solution for injection in a pre-filled pen
    EtanerceptInitial report18.12.2025OtherNepexto 50 mg solution for injection in a pre-filled pen
    Rifampicin sodiumChange notification18.12.2025OtherEremfat i.v. 600mg
    UrapidilChange notification18.12.2025Production problemUrapidil Bluefish 90 mg hard capsules, delayed release
    UrapidilChange notification18.12.2025Production problemUrapidil Bluefish 30 mg hard capsules, delayed release
    Hydromorphone hydrochlorideChange notification18.12.2025OtherHydromorphone PAINBREAK 8 mg prolonged-release tablets
    Hydromorphone hydrochlorideChange notification18.12.2025OtherHydromorphone PAINBREAK 4 mg prolonged-release tablets
    Hydromorphone hydrochlorideChange notification18.12.2025OtherHydromorphone PAINBREAK 24 mg prolonged-release tablets
    Hydromorphone hydrochlorideChange notification18.12.2025OtherHydromorphone PAINBREAK 16 mg prolonged-release tablets
    Dexamethasone dihydrogen phosphate disodium (Ph.Eur.)Initial report18.12.2025OtherDexafluid 1 mg/ml eye drops
    Ipratropium bromide (Ph.Eur.)Change notification18.12.2025Production problemIpratropium Teva 250 micrograms/1 ml solution for nebulizer
    Quetiapine fumarate (Ph.Eur.)Change notification18.12.2025OtherQuetiapine AbZ 150 mg prolonged-release tablets
    NitrendipineChange notification18.12.2025OtherNitrendipine AbZ 10 mg tablets
    Quetiapine fumarate (Ph.Eur.)Change notification18.12.2025OtherQuetiapine-ratiopharm 300 mg prolonged-release tablets
    Pramipexole dihydrochloride monohydrateChange notification18.12.2025OtherPramipexole-ratiopharm 0.52 mg prolonged-release tablets
    Propranolol hydrochlorideChange notification18.12.2025OtherPropra-ratiopharm 10 mg film-coated tablets
    Propranolol hydrochlorideChange notification18.12.2025OtherPropra-ratiopharm 40 mg film-coated tablets
    Propranolol hydrochlorideChange notification18.12.2025OtherPropra-ratiopharm 80 mg film-coated tablets
    NitrendipineChange notification18.12.2025OtherNitrendipine-ratiopharm 20 mg tablets
    Galantamine hydrobromideChange notification18.12.2025OtherGalantamine-ratiopharm 24 mg hard capsules, delayed release
    Galantamine hydrobromideChange notification18.12.2025OtherGalantamine-ratiopharm 16 mg hard capsules, delayed release
    Galantamine hydrobromideChange notification18.12.2025OtherGalantamine-ratiopharm 8 mg hard capsules, delayed release
    Doxepine hydrochloride (Ph.Eur.)Change notification18.12.2025OtherDoxepin-ratiopharm 50 mg film-coated tablets
    Doxepine hydrochloride (Ph.Eur.)Change notification18.12.2025OtherDoxepin-ratiopharm 25 mg film-coated tablets
    Dexamethasone dihydrogen phosphate disodium (Ph.Eur.)Change notification18.12.2025OtherDexa-ratiopharm 4 mg solution for injection
    Clonidine hydrochlorideChange notification18.12.2025OtherClonidine-ratiopharm 300
    Clonidine hydrochlorideChange notification18.12.2025OtherClonidine-ratiopharm 150
    Clonidine hydrochlorideChange notification18.12.2025OtherClonidine-ratiopharm 75
    Cinacalcet hydrochlorideChange notification18.12.2025OtherCinacalcet-ratiopharm 30 mg film-coated tablets
    AlprazolamChange notification18.12.2025OtherAlprazolam-ratiopharm 1.0 mg tablets
    AlprazolamChange notification18.12.2025OtherAlprazolam-ratiopharm 0.5 mg tablets
    NitrendipineChange notification18.12.2025OtherNitrendipine AL 10
    AnastrozoleChange notification18.12.2025OtherAnastrozole Denk 1 mg film-coated tablets
    Folic acid hydrate (with information on water content (1:x))Change notification18.12.2025OtherFolic acid AL 5 mg tablets
    Erythromycin lactobionateChange notification17.12.2025Production problemErythrocin-i.v. 1.0 g
    Methyldopa (Ph.Eur.)Change notification17.12.2025Production problemMethyldopa STADA 250 mg film-coated tablet
    Insulin aspartChange notification17.12.2025OtherNovoRapid PumpCart 100 E/ml solution for injection in cartridge – OP[5x(5×1.6ml)]
    Paliperidone palmitateChange notification17.12.2025OtherPaliperidone AL 50 mg Depot injection suspension in a pre-filled syringe
    AprepitantChange notification17.12.2025OtherAprepitant AL 80 mg hard capsules
    AprepitantChange notification17.12.2025OtherAprepitant AL 125 mg hard capsules
    AprepitantChange notification17.12.2025OtherAprepitant AL 125 mg and 80 mg hard capsules
    Zoledronic acid monohydrateChange notification17.12.2025OtherZoledronic acid AL 4 mg/100 ml solution for infusion
    Potassium canrenoateInitial report17.12.2025Production problemAldactone 10 ml Canrenoate
    Salbutamol sulfateInitial report16.12.2025OtherBronchospray novo
    Atorvastatin calcium trihydrate (Ph.Eur.)Change notification16.12.2025OtherAtorvastatin Micro Labs 10 mg film-coated tablets
    LevetiracetamChange notification16.12.2025Production problemLevetiracetam Holsten 250 mg film-coated tablets
    Moxifloxacin hydrochloride (Ph.Eur.) ((with information on water content (1:x)))Change notification16.12.2025OtherMoxifloxacin Holsten 400 mg film-coated tablets
    Quetiapine fumarate (Ph.Eur.)Change notification16.12.2025OtherQuetiapine AL 50 mg prolonged-release tablets
    PropofolInitial report16.12.2025Production problemPropofol-Lipuro 10 mg/ml
    Isosorbide mononitrateChange notification16.12.2025OtherISMN AL40 retard
    Isosorbide mononitrateChange notification16.12.2025OtherISMN AL 100 retard
    PrimidoneInitial report16.12.2025OtherPrimidone Holsten
    Amikacin sulfateChange notification16.12.2025Production problemAmikacin B. Braun 5 mg/ml infusion solution
    Amoxicillin trihydrateChange notification16.12.2025OtherAmoxicillin AL TS
    Cefixime 3 H<2>OChange notification16.12.2025OtherCefixime AL 100 mg/5 ml powder for oral suspension
    Dexketoprofen trometamolChange notification16.12.2025Production problemSympal inject 50 mg solution for injection/infusion
    Selegiline hydrochlorideChange notification16.12.2025OtherSelegiline AL 5
    Clonidine hydrochlorideChange notification15.12.2025Production problemClonistada 0.15 mg tablets
    Lidocaine hydrochloride monohydrateChange notification15.12.2025OtherXylocaine Gel 2%
    LidocaineChange notification15.12.2025OtherXYLOCAIN PUMP SPRAY dental
    Calcium chloride dihydrate; histidine; histidine hydrochloride monohydrate; potassium hydrogen 2-oxopentanedioate; potassium chloride; magnesium chloride hexahydrate; mannitol (Ph.Eur.); sodium chloride; tryptophanChange notification15.12.2025Production problemCustodiol
    Rosuvastatin calcium (Ph.Eur.)Change notification15.12.2025OtherRosuvastatin Aurobindo 20 mg film-coated tablets
    Buprenorphine hydrochlorideChange notification15.12.2025OtherBuprenorphine PUREN 8 mg sublingual tablets
    Atorvastatin calcium trihydrate (Ph.Eur.)Change notification15.12.2025OtherAtorvastatin PUREN 40 mg film-coated tablets
    AlprazolamChange notification15.12.2025OtherAlprazolam – 1 A Pharma 0.5 mg tablets
    OxytocinChange notification15.12.2025Production problemOxytocin 3 I.E. Hexal
    Galantamine hydrobromideChange notification15.12.2025OtherGalantamine – 1A Pharma 24 mg prolonged-release hard capsules
    Galantamine hydrobromideChange notification15.12.2025OtherGalantamine – 1A Pharma 8 mg prolonged-release hard capsules
    Galantamine hydrobromideChange notification15.12.2025OtherGalantamine – 1A Pharma 16 mg prolonged-release hard capsules
    OxcarbazepineChange notification15.12.2025OtherOxcarbazepine – 1 A Pharma 60 mg/ml oral suspension
    Quetiapine fumarate (Ph.Eur.)Change notification15.12.2025Production problemQuetiapine HEXAL 300 mg prolonged-release tablets
    Indapamide; Perindopril arginineInitial report15.12.2025OtherPerindopril arginine/indapamide Viatris 5 mg/1.25 mg film-coated tablets
  • 2025.12.22 [ フランス ]
    ANSMフランス供給不足情報（2025年12月15日～12月21日）
    Active ingredientsStatusUpdateSpecialty
    methylphenidateSupply tension19/12/2025Quasym LP, modified-release capsule
    fluorouracilSupply tension19/12/2025Fluorouracil Pfizer 50 mg/mL, solution for dilution for infusion – 20 mL and 100 mL vials
    medroxyprogesteroneSupply tension18/12/2025Depo Prodasone 500 mg, injectable suspension
    ifosfamideSupply tension18/12/2025Holoxan 1000 mg powder for solution for injection and 2000 mg powder for parenteral use
    synthetic vitamin A concentrate, oil formMarketing discontinuation17/12/2025Vitamin A Dulcis 25,000 IU per 100 g, ophthalmic ointment – (imported from Vitamin A Blache)
    ondansetronSupply tension17/12/2025Zophren 2 mg/mL, injectable solution in ampoule (IV)
    trandolaprilSupply tension17/12/2025Trandolapril 2 mg and 4 mg
    trandolaprilReturn to availability17/12/2025Trandolapril 0.5 mg, capsules
    venlafaxineSupply tension17/12/2025Specialties based on Venlafaxine LP 37.5 mg and LP 75 mg in extended-release capsules
    diltiazem (hydrochloride)Supply tension17/12/2025Tildiem 25 mg, powder and solution for intravenous injection
    amphotericin BReturn to availability15/12/2025Fungizone 10%, oral suspension
    venlafaxineReturn to availability15/12/2025Venlafaxine Viatris 50 mg, film-coated tablet
    digoxinReturn to availability15/12/2025Digoxin Nativelle 5 µg/0.1 ml, oral solution in drops
  • 2025.12.22 [ オーストラリア ]
    TGAオーストラリア供給不足情報（2025年12月15日～12月21日）
    rifampicinOral Liquid20 mg/mLAnticipatedAvailableUnexpected increase in consumer demand19/12/2025
    salbutamol sulfateInhalation, conventional3 mgCurrentUnavailableManufacturing19/12/2025
    salbutamol sulfateInhalation, conventional6 mgCurrentUnavailableManufacturing19/12/2025
    topiramateTablet, film coated50 mgResolvedAvailableManufacturing19/12/2025
    ciprofloxacin hydrochlorideTablet, film coated832.5 mgCurrentLimited AvailabilityManufacturing19/12/2025
    lamotrigineTablet, chewable200 mgResolvedAvailableManufacturing19/12/2025
    olanzapineTablet, orally disintegrating5 mgResolvedAvailableManufacturing19/12/2025
    pramipexole dihydrochloride monohydrateTablet.125 mgCurrentUnavailableManufacturing19/12/2025
    pramipexole dihydrochloride monohydrateTablet1 mgCurrentLimited AvailabilityManufacturing19/12/2025
    exemestaneTablet, sugar coated25 mgCurrentLimited AvailabilityManufacturing19/12/2025
    quetiapine fumarateTablet, modified release345.39 mgCurrentUnavailableManufacturing19/12/2025
    quetiapine fumarateTablet, modified release230.26 mgCurrentLimited AvailabilityManufacturing19/12/2025
    clindamycin hydrochlorideCapsule, hard162.87 mgResolvedAvailableManufacturing19/12/2025
    levetiracetamInjection, intravenous infusion100 mg/mLAnticipatedAvailableManufacturing19/12/2025
    phenylephrine hydrochloride~prednisolone acetateEye Drops, suspension1.2 mg/mL~10 mg/mLCurrentLimited AvailabilityUnexpected increase in consumer demand19/12/2025
    isotretinoinCapsule, soft20 mgAnticipatedAvailableManufacturing19/12/2025
    irbesartanTablet, film coated75 mgCurrentUnavailableManufacturing19/12/2025
    olmesartan medoxomil~hydrochlorothiazideTablet20 mg~12.5 mgCurrentUnavailableManufacturing19/12/2025
    acamprosate calciumTablet, enteric coated333 mgResolvedAvailableManufacturing19/12/2025
    lacosamideTablet, film coated50 mgAnticipatedAvailableManufacturing19/12/2025
    risperidoneTablet, film coated2 mgCurrentLimited AvailabilityManufacturing19/12/2025
    lorazepamTablet1 mgResolvedAvailableUnexpected increase in demand due to other sponsors unable to supply19/12/2025
    lamotrigineTablet, chewable200 mgCurrentLimited AvailabilityManufacturing19/12/2025
    levothyroxine sodiumTablet, uncoated200 microgramCurrentUnavailableManufacturing19/12/2025
    risperidoneOral Liquid, solution1 mg/mLCurrentUnavailableManufacturing19/12/2025
    ondansetron hydrochloride dihydrateTablet, film coated4.986 mgCurrentLimited AvailabilityManufacturing19/12/2025
    anastrozoleTablet, film coated1 mgAnticipatedAvailableManufacturing19/12/2025
    hydralazine hydrochlorideInjection, powder for20 mgCurrentUnavailableManufacturing19/12/2025
    isotretinoinCapsule, soft20 mgCurrentUnavailableManufacturing19/12/2025
    isotretinoinCapsule, soft10 mgCurrentUnavailableManufacturing19/12/2025
    teicoplanin~water for injectionsDiluent, not applicable~Injection, powder for400 mg~3.14 mLDiscontinuedReduction in supply until supply is exhaustedCommercial Changes / Commercial viability19/12/2025
    alfuzosin hydrochlorideTablet, modified release10 mgDiscontinuedReduction in supply until supply is exhaustedCommercial Changes / Commercial viability19/12/2025
    sodium pyrophosphateInjection, powder for30 mgCurrentUnavailableManufacturing18/12/2025
    doxorubicin hydrochlorideInjection2 mg/mLAnticipatedAvailableManufacturing18/12/2025
    atomoxetine hydrochlorideCapsule, hard11.43 mgCurrentUnavailableManufacturing18/12/2025
    cyproterone acetateTablet, uncoated100 mgAnticipatedAvailableManufacturing18/12/2025
    ambrisentanTablet, film coated5 mgAnticipatedAvailableManufacturing18/12/2025
    dantrolene sodium hemiheptahydrateInjection, powder for20 mgAnticipatedAvailableManufacturing17/12/2025
    glipizideTablet, uncoated5 mgResolvedAvailableManufacturing17/12/2025
    cyproterone acetateTablet, uncoated50 mgCurrentLimited AvailabilityManufacturing17/12/2025
    plerixaforInjection, solution20 mg/mLDiscontinuedReduction in supply until supply is exhaustedCommercial Changes / Commercial viability17/12/2025
    pramipexole dihydrochloride monohydrateTablet.125 mgCurrentUnavailableManufacturing17/12/2025
    atorvastatin calcium trihydrateTablet, film coated43.38 mgCurrentUnavailableManufacturing17/12/2025
    metformin hydrochlorideTablet, film coated1000 mgCurrentUnavailableManufacturing17/12/2025
    armodafinilTablet, uncoated250 mgResolvedAvailableTransport / Logistic issues / Storage capacity issues17/12/2025
    armodafinilTablet, uncoated150 mgResolvedAvailableTransport / Logistic issues / Storage capacity issues17/12/2025
    cisatracurium besilateInjection, solution7.04 mgCurrentLimited AvailabilityManufacturing17/12/2025
    metformin hydrochlorideTablet, modified release500 mgCurrentUnavailableManufacturing17/12/2025
    risperidoneOral Liquid, solution1 mg/mLCurrentUnavailableManufacturing17/12/2025
    levothyroxine sodiumTablet.075 mgAnticipatedAvailableManufacturing17/12/2025
    ramiprilTablet, uncoated1.25 mgDiscontinuedReduction in supply until supply is exhaustedCommercial Changes / Commercial viability17/12/2025
    TeriparatideInjection, solution250 microgram/mLCurrentUnavailableManufacturing17/12/2025
    metronidazoleTablet, film coated400 mgResolvedAvailableUnexpected increase in demand due to other sponsors unable to supply17/12/2025
    stannous chloride dihydrateInjection, powder for19.2 microgram/mLCurrentEmergency Supply OnlyManufacturing17/12/2025
    carbidopa monohydrate~levodopaTablet, uncoated26.9 mg~100 mgAnticipatedAvailableManufacturing17/12/2025
    labetalol hydrochlorideTablet, film coated200 mgAnticipatedAvailableManufacturing17/12/2025
    olanzapineTablet, film coated5 mgCurrentLimited AvailabilityTransport / Logistic issues / Storage capacity issues17/12/2025
    midazolamInjection, solution1 mg/mLResolvedAvailableManufacturing17/12/2025
    hydrochlorothiazide~enalapril maleateTablet, uncoated6 mg~20 mgResolvedAvailableManufacturing17/12/2025
    olanzapineWafer5 mgCurrentUnavailableTransport / Logistic issues / Storage capacity issues17/12/2025
    cefalexin monohydrateCapsule, hard263 mgDiscontinuedReduction in supply until supply is exhaustedCommercial Changes / Commercial viability17/12/2025
    metformin hydrochlorideTablet, film coated500 mgDiscontinuedReduction in supply until supply is exhaustedCommercial Changes / Commercial viability17/12/2025
    etoposide phosphateInjection, powder for1136 mgAnticipatedAvailableManufacturing17/12/2025
    gabapentinCapsule, hard400 mgCurrentLimited AvailabilityManufacturing16/12/2025
    cyproterone acetateTablet, uncoated50 mgCurrentUnavailableUnexpected increase in consumer demand16/12/2025
    calcitonin salmonInjection, solution100 IU/mLAnticipatedAvailableUnexpected increase in consumer demand16/12/2025
    valaciclovirTablet, film coated500 mgResolvedAvailableManufacturing16/12/2025
    benzathine benzylpenicillin tetrahydrateInjection, suspension1200000 USP UnitCurrentLimited AvailabilityManufacturing16/12/2025
    galantamine hydrobromideCapsule, modified release20.512 mgCurrentLimited AvailabilityUnexpected increase in demand due to other sponsors unable to supply16/12/2025
    galantamine hydrobromideCapsule, modified release30.768 mgCurrentUnavailableUnexpected increase in demand due to other sponsors unable to supply16/12/2025
    leflunomideTablet, film coated20 mgResolvedAvailableManufacturing16/12/2025
    SomatropinInjection, powder for12 mg/mLResolvedAvailableUnexpected increase in consumer demand16/12/2025
    atorvastatin calcium trihydrateTablet, film coated86.76 mgCurrentLimited AvailabilityManufacturing16/12/2025
    atorvastatin calcium trihydrateTablet, film coated21.69 mgCurrentUnavailableManufacturing16/12/2025
    valsartan~hydrochlorothiazideTablet, film coated160 mg~12.5 mgAnticipatedAvailableManufacturing16/12/2025
    oseltamivir phosphateOral Liquid, powder for7.88 mg/mLCurrentLimited AvailabilityUnexpected increase in consumer demand16/12/2025
    levodopa~carbidopa monohydrate~entacaponeTablet, film coated200 mg~54 mg~200 mgResolvedAvailableManufacturing16/12/2025
    levodopa~carbidopa monohydrate~entacaponeTablet, film coated75 mg~20.25 mg~200 mgResolvedAvailableManufacturing16/12/2025
    carbidopa monohydrate~entacapone~levodopaTablet, film coated13.5 mg~200 mg~50 mgResolvedAvailableManufacturing16/12/2025
    levodopa~entacapone~carbidopa monohydrateTablet, film coated100 mg~200 mg~27 mgResolvedAvailableManufacturing16/12/2025
    entacapone~levodopa~carbidopa monohydrateTablet, film coated200 mg~125 mg~33.75 mgResolvedAvailableManufacturing16/12/2025
    entacapone~carbidopa monohydrate~levodopaTablet, film coated200 mg~40.5 mg~150 mgResolvedAvailableManufacturing16/12/2025
    risperidoneTablet, film coated3 mgCurrentLimited AvailabilityManufacturing16/12/2025
    methylphenidate hydrochlorideCapsule, modified release60 mgCurrentLimited AvailabilityManufacturing16/12/2025
    quetiapine fumarateTablet, modified release57.5 mgCurrentLimited AvailabilityUnexpected increase in consumer demand16/12/2025
    stiripentolCapsule500 mgAnticipatedAvailableManufacturing16/12/2025
    lacosamideTablet, film coated100 mgResolvedAvailableManufacturing16/12/2025
    metaraminol tartrateInjection, solution19 mgCurrentUnavailableManufacturing16/12/2025
    montelukast sodiumTablet, chewable5.2 mgResolvedAvailableManufacturing16/12/2025
    nitrofurantoinCapsule, hard100 mgCurrentUnavailableUnexpected increase in consumer demand16/12/2025
    sacubitril~valsartanTablet, film coated97.2 mg~102.8 mgCurrentUnavailableManufacturing16/12/2025
    rivaroxabanTablet, film coated15 mgResolvedAvailableManufacturing16/12/2025
    nitrofurantoinCapsule, hard100 mgCurrentLimited AvailabilityUnexpected increase in consumer demand16/12/2025
    aripiprazole monohydrateInjection, powder for416.07 mgCurrentUnavailableManufacturing16/12/2025
    lidocaine hydrochlorideInjection, solution10 mg/mLResolvedAvailableManufacturing16/12/2025
    pramipexole dihydrochloride monohydrateTablet, uncoated1 mgResolvedAvailableUnexpected increase in demand due to other sponsors unable to supply16/12/2025
    pramipexole dihydrochloride monohydrateTablet, uncoated.125 mgResolvedAvailableUnexpected increase in demand due to other sponsors unable to supply16/12/2025
    diltiazem hydrochlorideCapsule, modified release180 mgCurrentLimited AvailabilityManufacturing16/12/2025
    diltiazem hydrochlorideCapsule, modified release360 mgCurrentUnavailableManufacturing16/12/2025
    diltiazem hydrochlorideCapsule, modified release360 mgAnticipatedAvailableManufacturing16/12/2025
    flunitrazepamTablet, film coated1 mgCurrentLimited AvailabilityManufacturing16/12/2025
    methylphenidate hydrochlorideCapsule, modified release20 mgCurrentLimited AvailabilityManufacturing16/12/2025
    methylphenidate hydrochlorideCapsule, modified release30 mgResolvedAvailableManufacturing16/12/2025
    methylphenidate hydrochlorideCapsule, modified release40 mgCurrentUnavailableManufacturing16/12/2025
    simvastatinTablet, film coated5 mgCurrentLimited AvailabilityManufacturing16/12/2025
    Pancreatic extractCapsule, enteric300 mgCurrentLimited AvailabilityUnexpected increase in consumer demand15/12/2025
    lansoprazoleCapsule, enteric30 mgResolvedAvailableManufacturing15/12/2025
    avanafilTablet, uncoated200 mgAnticipatedAvailableUnexpected increase in consumer demand15/12/2025
    benzathine benzylpenicillin tetrahydrateInjection, suspension600000 USP UnitCurrentUnavailableManufacturing15/12/2025
    lacosamideTablet, film coated50 mgResolvedAvailableManufacturing15/12/2025
    lacosamideTablet, film coated150 mgResolvedAvailableManufacturing15/12/2025
    Pancreatic extractCapsule420 mgCurrentLimited AvailabilityUnexpected increase in consumer demand15/12/2025
    estradiolDrug delivery system, transdermal1.17 mgCurrentUnavailableManufacturing15/12/2025
    lanreotide acetateInjection, solution133.33 mgCurrentUnavailableManufacturing15/12/2025
    lanreotide acetateInjection, solution100 mgCurrentUnavailableManufacturing15/12/2025
    imipramine hydrochlorideTablet, sugar coated25 mgCurrentUnavailableManufacturing15/12/2025
  • 2025.12.22 [ 米国 ]
    ASHP供給不足情報（2025年12月15日～12月21日）
    Generic NameShortage StatusRevision DateCreated Date
    Insulin Aspart InjectionCurrent Shortages19-Dec-2510-Nov-23
    Lenalidomide CapsulesCurrent Shortages19-Dec-2511-Jan-24
    Lidocaine InjectionCurrent Shortages19-Dec-2523-Jun-15
    Posaconazole InjectionResolved Shortages19-Dec-2518-Dec-25
    Dorzolamide Ophthalmic SolutionCurrent Shortages18-Dec-2519-Jun-24
    Fentanyl Citrate InjectionCurrent Shortages18-Dec-258-May-17
    Methylprednisolone Acetate InjectionCurrent Shortages18-Dec-2525-Aug-25
    Methylprednisolone Sodium Succinate InjectionCurrent Shortages18-Dec-2523-Mar-23
    Metyrosine CapsulesCurrent Shortages18-Dec-253-Sep-25
    Mometasone Furoate Aerosol for Oral InhalationCurrent Shortages18-Dec-2529-Jul-25
    Mometasone Furoate and Formoterol Fumarate Inhalation AerosolCurrent Shortages18-Dec-2529-Aug-25
    Nalbuphine InjectionCurrent Shortages18-Dec-258-Nov-22
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    Penicillin V Potassium Oral PresentationsCurrent Shortages18-Dec-2517-May-23
    Somatropin InjectionResolved Shortages18-Dec-2522-Nov-22
    Terbutaline Sulfate InjectionCurrent Shortages18-Dec-2521-Jan-25
    5% Dextrose Injection Small Volume BagsCurrent Shortages16-Dec-254-Feb-22
    Acyclovir InjectionCurrent Shortages16-Dec-2516-Dec-25
    Dobutamine InjectionCurrent Shortages16-Dec-251-Mar-17
    Dopamine Hydrochloride InjectionCurrent Shortages16-Dec-259-Mar-22
    Fluorescein Sodium and Proparacaine Hydrochloride Ophthalmic SolutionCurrent Shortages16-Dec-2526-Jul-19
    Flurazepam CapsulesResolved Shortages16-Dec-2510-Nov-23
    Gentamicin InjectionCurrent Shortages16-Dec-2522-Feb-21
    Haloperidol Lactate InjectionCurrent Shortages16-Dec-259-Dec-20
    Lanthanum Carbonate Oral PresentationsCurrent Shortages16-Dec-252-Apr-25
    Naltrexone TabletsCurrent Shortages16-Dec-257-Feb-24
    Valproate Sodium InjectionCurrent Shortages16-Dec-2513-Aug-25
    Vancomycin Hydrochloride InjectionCurrent Shortages16-Dec-251-Jun-15
    Bacitracin Ophthalmic OintmentCurrent Shortages15-Dec-2512-Sep-24
    Eptifibatide InjectionCurrent Shortages15-Dec-2520-May-20
    Moxifloxacin TabletsCurrent Shortages15-Dec-256-Dec-23
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  • 2025.12.22 [ 米国 ]
    FDA供給不足情報：新規・更新（2025年12月15日～12月21日）
    New

    December 19, 2025

     

    Updated

    December 19, 2025

    December 18, 2025

    December 17, 2025

    December 16, 2025

    December 15, 2025

  • 2025.12.16 [ 英国 ]
    NICE医薬品情報サービス（2025年12月8日〜2025年12月12日）

    Medicine supply notification: Nifedipine (Fortipine® LA) 40mg modified-release tablets

    2025年12月8日、保健・社会福祉省（Department of Health and Social Care：DHSC）は、Nifedipine (Fortipine® LA) 40mg徐放性錠の医薬品供給通知（medicine supply notification）を発出した。

    • Nifedipine (Fortipine® LA)40mg徐放性錠剤は現在在庫切れ。再入荷日は未定。
    • 他のブランドのNifedipin20mg徐放性錠剤は引き続き入手可能であり、需要増加に対応可能。
    • Nifedipine (Coracten® SR) 20mg徐放性カプセルは引き続き入手可能であり、需要増加に対応可能。
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