更新された供給不足状況を示しています。
ある時点での供給不足の全体的状況は「供給関連情報」に定期的にアップします。
米国
- 2025.10.27
Generic Name Shortage Status Revision Date Amiodarone Injection Current Shortages 22-Oct-25 Clindamycin Phosphate Injection Current Shortages 22-Oct-25 Dexamethasone Oral Solution/Elixir Current Shortages 22-Oct-25 Hydrocortisone Sodium Succinate Injection Resolved Shortages 22-Oct-25 Morphine Injection Current Shortages 22-Oct-25 Sodium Bicarbonate Injection Current Shortages 22-Oct-25 Vasopressin Injection Current Shortages 22-Oct-25 Vecuronium Bromide Injection Current Shortages 22-Oct-25 Albuterol sulfate and Ipratropium Bromide Inhalation Solution Current Shortages 21-Oct-25 Dorzolamide Ophthalmic Solution Current Shortages 21-Oct-25 Nalbuphine Injection Current Shortages 20-Oct-25 Nitroglycerin Injection Current Shortages 20-Oct-25 Penicillin G Benzathine Current Shortages 20-Oct-25 Potassium Chloride Injection Current Shortages 20-Oct-25 - 2025.10.27
New
October 24, 2025
- Busulfan Injection (Discontinuation)
- Insulin Glargine Injection (Discontinuation)
- Insulin Lispro Injection (Discontinuation)
- Insulin Lispro-aabc Injection (Discontinuation)
- Lorazepam Injection (Currently in Shortage)
October 21, 2025
- Tranylcypromine Sulfate Tablet (Discontinuation)
October 20, 2025
- Oxaliplatin Injection (Discontinuation)
Updated
October 24, 2025
- Dexamethasone Sodium Phosphate Injection (Currently in Shortage)
October 23, 2025
- Bupivacaine Hydrochloride Injection (Currently in Shortage)
- Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Lorazepam Injection (Currently in Shortage)
- Meperidine Hydrochloride Injection (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Penicillin G Benzathine Injection (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- Sterile Water Injection (Currently in Shortage)
- Sufentanil Citrate Injection (Currently in Shortage)
October 22, 2025
- Amino Acid Injection (Currently in Shortage)
- Clindamycin Phosphate Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Heparin Sodium Injection (Currently in Shortage)
- Nitroglycerin Injection (Currently in Shortage)
- Sterile Water Irrigant (Currently in Shortage)
October 21, 2025
- Dextrose Monohydrate 10% Injection (Currently in Shortage)
- Fentanyl Citrate Injection (Currently in Shortage)
- Heparin Sodium Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Lisdexamfetamine Dimesylate Tablet, Chewable (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Naltrexone Hydrochloride Tablet (Currently in Shortage)
- Remifentanil Hydrochloride Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Ropivacaine Hydrochloride Injection (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- Technetium TC-99M Pyrophosphate Kit Injection (Currently in Shortage)
- 2025.10.20
- 2025.10.20
New
October 17, 2025
- Elbasvir; Grazoprevir Tablet (Discontinuation)
October 16, 2025
- Pemetrexed Disodium Injection (Discontinuation)
- Vigabatrin Oral Solution (Discontinuation)
- Voriconazole Injection (Discontinuation)
Updated
October 17, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Dexamethasone Sodium Phosphate Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
October 16, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Azacitidine Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
October 15, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Bupivacaine Hydrochloride Injection (Currently in Shortage)
- Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Currently in Shortage)
- Dobutamine Hydrochloride Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Lorazepam Injection (Currently in Shortage)
- Meperidine Hydrochloride Injection (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Midazolam Hydrochloride Injection (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Penicillin G Benzathine Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- Sterile Water Injection (Currently in Shortage)
- Sufentanil Citrate Injection (Currently in Shortage)
- 2025.10.13
Generic Name Shortage Status Revision Date Rocuronium Injection Current Shortages 9-Oct-25 Budesonide Suspension for Inhalation Current Shortages 7-Oct-25 Difluprednate Ophthalmic Emulsion Current Shortages 7-Oct-25 Magnesium Sulfate Injection Current Shortages 7-Oct-25 Oseltamivir Oral Suspension and Capsules Current Shortages 7-Oct-25 Remifentanil Injection Current Shortages 7-Oct-25 Triamcinolone Acetonide Injectable Suspension Current Shortages 7-Oct-25 Bupivacaine Injection Current Shortages 6-Oct-25 Dulaglutide Injection Current Shortages 6-Oct-25 Leucovorin Calcium Injection Current Shortages 6-Oct-25 Lidocaine Hydrochloride Oral Topical Solution (Viscous) 2% Current Shortages 6-Oct-25 Mometasone Furoate and Formoterol Fumarate Inhalation Aerosol Current Shortages 6-Oct-25 Oxycodone Hydrochloride and Acetaminophen Tablets Current Shortages 6-Oct-25 Paricalcitol Capsules Current Shortages 6-Oct-25 Sodium Bicarbonate Injection Current Shortages 6-Oct-25 Vancomycin Hydrochloride Injection Current Shortages 6-Oct-25 - 2025.10.13
New
October 10, 2025
- Pemetrexed Disodium Injection (Discontinuation)
October 09, 2025
- Adalimumab-afzb Injection (Discontinuation)
- Hydrocortisone Sodium Succinate Injection (Currently in Shortage)
- Omeprazole Delayed Release Capsule (Discontinuation)
October 07, 2025
- Cobicistat Tablet (Discontinuation)
- Paricalcitol Capsule (Discontinuation)
Updatede
October 09, 2025
- Dexmedetomidine Hydrochloride Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
October 08, 2025
- Azacitidine Injection (Currently in Shortage)
- Bupivacaine Hydrochloride Injection (Currently in Shortage)
- Carboplatin Injection (Currently in Shortage)
- Dexamethasone Sodium Phosphate Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Penicillin G Benzathine Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Ropivacaine Hydrochloride Injection (Currently in Shortage)
October 06, 2025
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- 2025.10.05
- 2025.10.05
New
October 01, 2025
- Hydrochlorothiazide; Quinapril Hydrochloride Tablet (Discontinuation)
- Quinapril Hydrochloride Tablet (Discontinuation)
September 30, 2025
- Oseltamivir Phosphate Capsule (Discontinuation)
September 29, 2025
- Fondaparinux Sodium Injection (Discontinuation)
- Tafamidis Meglumine Capsule (Discontinuation)
- Triazolam Tablet (Discontinuation)
Updated
October 03, 2025
- Lactated Ringers Injection (Resolved)
- Lactated Ringers Injection (Discontinuation)
October 02, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Azacitidine Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methylphenidate Film, Extended Release (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
October 01, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Currently in Shortage)
- Epinephrine Bitartrate, Lidocaine Hydrochloride Injection (Currently in Shortage)
- Fentanyl Citrate Injection (Currently in Shortage)
- Heparin Sodium Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Naltrexone Hydrochloride Tablet (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
September 29, 2025
- Desmopressin Acetate Spray (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Metronidazole Injection (Currently in Shortage)
カナダ
カナダの情報はありません。
オーストラリア
- 2025.10.27
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated prazosin hydrochloride Tablet, uncoated 1.095 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 prazosin hydrochloride Tablet, uncoated 2.19 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 prazosin hydrochloride Tablet, uncoated 5.476 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 ramipril Tablet, uncoated 1.25 mg Resolved Available Manufacturing 24/10/2025 trandolapril Capsule 2 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 risperidone Tablet, film coated 2 mg Current Limited Availability Manufacturing 24/10/2025 bisoprolol fumarate Tablet 2.5 mg Current Unavailable Manufacturing 24/10/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.9 mg Current Limited Availability Unexpected increase in consumer demand 24/10/2025 exemestane Tablet, sugar coated 25 mg Anticipated Available Manufacturing 24/10/2025 indapamide hemihydrate Tablet, sugar coated 2.5 mg Current Limited Availability Manufacturing 24/10/2025 ropivacaine hydrochloride Injection, solution 200 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 24/10/2025 clopidogrel besilate Tablet, film coated 112.1 mg Current Unavailable Manufacturing 24/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Unexpected increase in consumer demand 24/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Unexpected increase in consumer demand 24/10/2025 rosuvastatin calcium Tablet, film coated 10.42 mg Current Unavailable Manufacturing 24/10/2025 pregabalin Capsule, hard 150 mg Current Limited Availability Unexpected increase in consumer demand 24/10/2025 levetiracetam Solution 100 mg/mL Resolved Available Manufacturing 24/10/2025 clonidine hydrochloride Tablet 100 microgram Resolved Available Unexpected increase in consumer demand 24/10/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Manufacturing 24/10/2025 tranexamic acid Tablet, film coated 500 mg Current Unavailable Manufacturing 24/10/2025 cyproterone acetate Tablet, uncoated 50 mg Current Unavailable Manufacturing 24/10/2025 hydrocortisone Tablet, uncoated 4 mg Current Limited Availability Manufacturing 24/10/2025 nizatidine Capsule, hard 150 mg Resolved Available Manufacturing 24/10/2025 nizatidine Capsule, hard 150 mg Current Unavailable Manufacturing 24/10/2025 rasagiline mesilate Tablet 1.56 mg Anticipated Available Manufacturing 24/10/2025 ambrisentan Tablet, film coated 10 mg Anticipated Available Manufacturing 24/10/2025 teriflunomide Tablet, film coated 14 mg Current Limited Availability Manufacturing 24/10/2025 gabapentin Tablet, film coated 600 mg Anticipated Available Manufacturing 24/10/2025 hydrochlorothiazide~amlodipine besilate~olmesartan medoxomil Tablet, film coated 12.5 mg~13.9 mg~40 mg Current Limited Availability Manufacturing 24/10/2025 paclitaxel Injection, powder for 100 mg Current Limited Availability Manufacturing 24/10/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 ethinylestradiol~norethisterone Tablet, uncoated 36 microgram~500 microgram Anticipated Available Manufacturing 24/10/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated 1 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 prazosin hydrochloride Tablet, uncoated 1.1 mg Current Unavailable Manufacturing 24/10/2025 prazosin hydrochloride Tablet, uncoated 2.2 mg Current Unavailable Manufacturing 24/10/2025 prazosin hydrochloride Tablet, uncoated 5.5 mg Current Unavailable Manufacturing 24/10/2025 trandolapril Capsule 4 mg Resolved Available Manufacturing 24/10/2025 dinoprostone Gel .6667 mg/g Anticipated Available Manufacturing 24/10/2025 risperidone Tablet, film coated 2 mg Resolved Available Manufacturing 23/10/2025 topiramate Tablet, film coated 25 mg Current Unavailable Manufacturing 23/10/2025 olanzapine Tablet, orally disintegrating 20 mg Resolved Available Manufacturing 23/10/2025 phenoxymethylpenicillin potassium Oral Liquid, powder for 28.284 mg/mL Current Unavailable Manufacturing 23/10/2025 levetiracetam Tablet, film coated 500 mg Current Unavailable Manufacturing 23/10/2025 levetiracetam Tablet, film coated 1000 mg Current Unavailable Manufacturing 23/10/2025 olanzapine Tablet, orally disintegrating 10 mg Current Unavailable Manufacturing 23/10/2025 olanzapine Tablet, orally disintegrating 5 mg Current Unavailable Manufacturing 23/10/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in consumer demand 23/10/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Limited Availability Manufacturing 23/10/2025 sildenafil citrate Tablet, film coated 28.1 mg Current Unavailable Manufacturing 23/10/2025 isotretinoin Capsule, soft 10 mg Current Unavailable Manufacturing 23/10/2025 isotretinoin Capsule, soft 20 mg Current Unavailable Manufacturing 23/10/2025 ezetimibe~simvastatin Tablet 10 mg~10 mg Current Unavailable Manufacturing 23/10/2025 ezetimibe~simvastatin Tablet 10 mg~20 mg Current Unavailable Manufacturing 23/10/2025 rosuvastatin calcium Tablet, film coated 20.84 mg Current Unavailable Unexpected increase in consumer demand 23/10/2025 ezetimibe Tablet, uncoated 10 mg Current Unavailable Unexpected increase in consumer demand 23/10/2025 irbesartan Tablet, film coated 150 mg Resolved Available Manufacturing 23/10/2025 cyproterone acetate Tablet, uncoated 100 mg Anticipated Available Manufacturing 23/10/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Current Unavailable Manufacturing 23/10/2025 efavirenz~tenofovir disoproxil maleate~emtricitabine Tablet, film coated 600 mg~300 mg~200 mg Current Unavailable Manufacturing 23/10/2025 olmesartan medoxomil~hydrochlorothiazide Tablet 20 mg~12.5 mg Anticipated Available Manufacturing 23/10/2025 bimatoprost Eye Drops .3 mg/mL Anticipated Available Manufacturing 23/10/2025 nitrofurantoin Capsule, hard 100 mg Resolved Available Manufacturing 23/10/2025 Teriparatide Injection, solution .25 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 23/10/2025 naltrexone hydrochloride Tablet, film coated 50 mg Anticipated Available Manufacturing 23/10/2025 levothyroxine sodium Tablet 200 microgram Current Unavailable Unexpected increase in consumer demand 23/10/2025 rivaroxaban Tablet, film coated 10 mg Anticipated Available Manufacturing 23/10/2025 tamoxifen citrate Tablet, uncoated 15.2 mg Current Unavailable Manufacturing 23/10/2025 tamoxifen citrate Tablet, uncoated 30.4 mg Current Unavailable Manufacturing 23/10/2025 isotretinoin Capsule, soft 20 mg Current Unavailable Manufacturing 23/10/2025 isotretinoin Capsule, soft 10 mg Anticipated Available Manufacturing 23/10/2025 mupirocin Ointment 20 mg/g Current Unavailable Manufacturing 23/10/2025 lidocaine hydrochloride Injection, solution 10 mg/mL Resolved Available Manufacturing 23/10/2025 ropivacaine hydrochloride Injection, solution 10 mg/mL Resolved Available Manufacturing 23/10/2025 phenylephrine hydrochloride Injection, solution 10 mg/mL Anticipated Available Manufacturing 22/10/2025 galantamine hydrobromide Capsule, modified release 30.768 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 22/10/2025 mycophenolate mofetil Tablet, film coated 500 mg Current Limited Availability Manufacturing 22/10/2025 letrozole Tablet, film coated 2.5 mg Current Unavailable Manufacturing 22/10/2025 atorvastatin calcium trihydrate~amlodipine besilate Tablet, film coated 43.376 mg~6.94 mg Current Unavailable Manufacturing 22/10/2025 atorvastatin calcium trihydrate~amlodipine besilate Tablet, film coated 10.844 mg~13.88 mg Current Unavailable Manufacturing 22/10/2025 milrinone Injection, concentrated 10 mg Current Unavailable Manufacturing 22/10/2025 fingolimod hydrochloride Capsule 560 microgram Anticipated Available Manufacturing 22/10/2025 phenytoin sodium Injection, solution 250 mg Current Limited Availability Manufacturing 22/10/2025 bromazepam Tablet, uncoated 6 mg Resolved Available Transport / Logistic issues / Storage capacity issues 22/10/2025 bisoprolol fumarate Tablet 2.5 mg Current Unavailable Manufacturing 21/10/2025 ropivacaine hydrochloride Injection, solution 10 mg/mL Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 21/10/2025 clindamycin hydrochloride Capsule, hard 162.87 mg Anticipated Available Manufacturing 21/10/2025 mesalazine Tablet, enteric coated 800 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 21/10/2025 acamprosate calcium Tablet, enteric coated 333 mg Anticipated Available Manufacturing 21/10/2025 moxonidine Tablet, film coated 400 microgram Current Limited Availability Manufacturing 21/10/2025 paroxetine hydrochloride Tablet, film coated 22.22 mg Anticipated Available Manufacturing 21/10/2025 carvedilol Tablet, film coated 6.25 mg Anticipated Available Manufacturing 21/10/2025 lamotrigine Tablet, chewable 100 mg Current Limited Availability Manufacturing 21/10/2025 lamotrigine Tablet, chewable 200 mg Anticipated Available Manufacturing 21/10/2025 ondansetron hydrochloride dihydrate Tablet, film coated 4.986 mg Anticipated Available Manufacturing 21/10/2025 famciclovir Tablet, film coated 250 mg Current Unavailable Manufacturing 21/10/2025 famciclovir Tablet, film coated 500 mg Current Unavailable Manufacturing 21/10/2025 ondansetron hydrochloride dihydrate Injection, solution 5 mg Current Unavailable Manufacturing 20/10/2025 midazolam Injection, solution 50 mg Current Limited Availability Manufacturing 20/10/2025 vecuronium bromide Injection, powder for 10 mg Resolved Available Manufacturing 20/10/2025 salmeterol xinafoate~fluticasone propionate Inhalation, powder for 72.5 microgram/actuation~250 microgram/actuation Resolved Available Unexpected increase in consumer demand 20/10/2025 desvenlafaxine Tablet, modified release 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 20/10/2025 desvenlafaxine Tablet, modified release 50 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 20/10/2025 methylphenidate hydrochloride Capsule, modified release 60 mg Current Limited Availability Manufacturing 20/10/2025 ezetimibe~simvastatin Tablet 10 mg~40 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 20/10/2025 amiodarone hydrochloride Tablet, uncoated 100 mg Current Unavailable Manufacturing 20/10/2025 sugammadex sodium Injection, solution 217.6 mg Current Unavailable Manufacturing 20/10/2025 risperidone Oral Liquid, solution 1 mg/mL Current Limited Availability Manufacturing 20/10/2025 rifampicin Capsule, hard 150 mg Current Limited Availability Manufacturing 20/10/2025 Peginterferon alfa2a Injection, solution 135 microgram Current Unavailable Unexpected increase in consumer demand 20/10/2025 Peginterferon alfa2a Injection, solution 180 microgram Current Unavailable Unexpected increase in consumer demand 20/10/2025 - 2025.10.20
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated desvenlafaxine Tablet, modified release 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 20/10/2025 desvenlafaxine Tablet, modified release 50 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 20/10/2025 ezetimibe~simvastatin Tablet 10 mg~40 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 20/10/2025 risperidone Oral Liquid, solution 1 mg/mL Current Limited Availability Manufacturing 20/10/2025 rivaroxaban Tablet, film coated 10 mg Anticipated Available Manufacturing 20/10/2025 rifampicin Capsule, hard 150 mg Current Limited Availability Manufacturing 20/10/2025 phenytoin sodium Injection, solution 100 mg Current Unavailable Manufacturing 17/10/2025 ciprofloxacin hydrochloride Tablet, film coated 555 mg Anticipated Available Manufacturing 17/10/2025 sildenafil citrate Tablet, uncoated 35.1 mg Current Limited Availability Manufacturing 17/10/2025 glipizide Tablet, uncoated 5 mg Anticipated Available Manufacturing 17/10/2025 mesalazine Tablet, modified release 1 g Current Limited Availability Transport / Logistic issues / Storage capacity issues 17/10/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Current Unavailable Manufacturing 17/10/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Current Limited Availability Manufacturing 17/10/2025 montelukast sodium Tablet, chewable 5.2 mg Anticipated Available Manufacturing 17/10/2025 carbidopa monohydrate~levodopa~entacapone Tablet, film coated 54 mg~200 mg~200 mg Current Unavailable Manufacturing 17/10/2025 entacapone~carbidopa monohydrate~levodopa Tablet, film coated 200 mg~20.25 mg~75 mg Current Unavailable Manufacturing 17/10/2025 entacapone~levodopa~carbidopa monohydrate Tablet, film coated 200 mg~50 mg~13.5 mg Current Limited Availability Manufacturing 17/10/2025 levodopa~entacapone~carbidopa monohydrate Tablet, film coated 100 mg~200 mg~27 mg Current Unavailable Manufacturing 17/10/2025 entacapone~levodopa~carbidopa monohydrate Tablet, film coated 200 mg~125 mg~33.75 mg Current Unavailable Manufacturing 17/10/2025 carbidopa monohydrate~levodopa~entacapone Tablet, film coated 40.5 mg~150 mg~200 mg Current Unavailable Manufacturing 17/10/2025 pregabalin Capsule, hard 150 mg Current Limited Availability Unexpected increase in consumer demand 17/10/2025 risperidone Tablet, film coated 2 mg Anticipated Available Manufacturing 17/10/2025 gabapentin Tablet, film coated 600 mg Anticipated Available Manufacturing 17/10/2025 metaraminol tartrate Injection, solution 19 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 17/10/2025 amlodipine besilate~olmesartan medoxomil~hydrochlorothiazide Tablet, film coated 13.9 mg~40 mg~12.5 mg Anticipated Available Manufacturing 17/10/2025 naltrexone hydrochloride Tablet, film coated 50 mg Anticipated Available Manufacturing 17/10/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 17/10/2025 prazosin hydrochloride Tablet, uncoated 1.095 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 tobramycin Injection, solution 80 mg Anticipated Available Manufacturing 16/10/2025 tetracosactide Injection, modified release 1 mg/mL Current Unavailable Manufacturing 16/10/2025 dienogest~ethinylestradiol Tablet, sugar coated 2 mg~.03 mg Anticipated Available Manufacturing 16/10/2025 codeine phosphate hemihydrate Oral Liquid, solution 5 mg/mL Current Unavailable Manufacturing 16/10/2025 ciprofloxacin hydrochloride Tablet, film coated 277.5 mg Current Unavailable Manufacturing 16/10/2025 ciprofloxacin hydrochloride Tablet, film coated 832.5 mg Anticipated Available Manufacturing 16/10/2025 midazolam Injection, solution 5 mg/mL Anticipated Available Manufacturing 16/10/2025 olsalazine sodium Capsule 250 mg Current Unavailable Manufacturing 16/10/2025 finasteride Tablet, film coated 1 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 lumefantrine~artemether Tablet, dispersible 120 mg~20 mg Discontinued Unavailable Commercial Changes / Commercial viability 16/10/2025 bisoprolol fumarate Tablet 5 mg Anticipated Available Manufacturing 16/10/2025 levetiracetam Tablet, film coated 500 mg Current Limited Availability Manufacturing 16/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 16/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Manufacturing 16/10/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 16/10/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 16/10/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 16/10/2025 sildenafil citrate Tablet, film coated 28.1 mg Current Unavailable Manufacturing 16/10/2025 ezetimibe~rosuvastatin calcium Tablet~Tablet, film coated 10 mg~41.583 mg Resolved Available Manufacturing 16/10/2025 oxytocin Injection, solution 5 IU/mL Resolved Available Unexpected increase in consumer demand 16/10/2025 oxytocin Injection, solution 10 IU/mL Resolved Available Manufacturing 16/10/2025 atorvastatin calcium trihydrate~ezetimibe Tablet, multilayer 10.9 mg~10 mg Resolved Available Manufacturing 16/10/2025 ezetimibe Tablet, uncoated 10 mg Current Unavailable Unexpected increase in consumer demand 16/10/2025 nicorandil Tablet, uncoated 10 mg Current Limited Availability Manufacturing 16/10/2025 tadalafil Tablet, film coated 5 mg Current Limited Availability Manufacturing 16/10/2025 latanoprost Eye Drops, solution .05 mg/mL Anticipated Available Manufacturing 16/10/2025 escitalopram oxalate Tablet, film coated 25.47 mg Current Limited Availability Manufacturing 16/10/2025 eplerenone Tablet, film coated 25 mg Resolved Available Manufacturing 16/10/2025 lacosamide Tablet, film coated 50 mg Anticipated Available Manufacturing 16/10/2025 ambrisentan Tablet, film coated 5 mg Anticipated Available Manufacturing 16/10/2025 nitrofurantoin Capsule, hard 100 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 methylphenidate hydrochloride Tablet, modified release 54 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 methylphenidate hydrochloride Tablet, modified release 27 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 olsalazine sodium Tablet, uncoated 500 mg Current Unavailable Manufacturing 16/10/2025 estradiol hemihydrate Drug delivery system, transdermal 3.09 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 hydrochlorothiazide~enalapril maleate Tablet, uncoated 6 mg~20 mg Anticipated Available Manufacturing 16/10/2025 valaciclovir hydrochloride Tablet, film coated 1112 mg Current Limited Availability Manufacturing 16/10/2025 estradiol hemihydrate Drug delivery system, transdermal 2.32 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 galantamine~galantamine hydrobromide Capsule, modified release 16 mg~20.51 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 diclofenac sodium Tablet, enteric coated 50 mg Discontinued Unavailable Commercial Changes / Commercial viability 15/10/2025 propranolol hydrochloride Tablet, film coated 10 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 15/10/2025 propranolol hydrochloride Tablet, film coated 40 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 15/10/2025 alfentanil hydrochloride Injection, solution 1.0876 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 15/10/2025 pregabalin Capsule, hard 150 mg Resolved Available Manufacturing 15/10/2025 pregabalin Capsule, hard 75 mg Resolved Available Manufacturing 15/10/2025 dabigatran etexilate mesilate Capsule, hard 126.83 mg Resolved Available Manufacturing 15/10/2025 lurasidone hydrochloride Tablet, film coated 80 mg Current Unavailable Manufacturing 15/10/2025 rivaroxaban Tablet, film coated 15 mg Anticipated Available Manufacturing 15/10/2025 levothyroxine sodium Tablet 50 microgram Current Unavailable Unexpected increase in consumer demand 15/10/2025 metronidazole Tablet, film coated 400 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 15/10/2025 rifampicin Capsule, hard 300 mg Current Unavailable Manufacturing 15/10/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 15/10/2025 diclofenac sodium Tablet, enteric coated 25 mg Discontinued Unavailable Commercial Changes / Commercial viability 14/10/2025 valaciclovir hydrochloride Tablet, film coated 556.275 mg Resolved Available Manufacturing 14/10/2025 methylphenidate hydrochloride Capsule, modified release 10 mg Current Limited Availability Manufacturing 14/10/2025 ephedrine sulfate Injection, solution 30 mg/mL Anticipated Available Manufacturing 14/10/2025 montelukast sodium Tablet, chewable 5.2 mg Resolved Available Manufacturing 14/10/2025 primaquine phosphate Tablet, uncoated 13.2 mg Anticipated Available Manufacturing 14/10/2025 methylphenidate hydrochloride Capsule, modified release 60 mg Current Unavailable Manufacturing 14/10/2025 olmesartan medoxomil~hydrochlorothiazide Tablet 20 mg~12.5 mg Anticipated Available Manufacturing 14/10/2025 atenolol Tablet, film coated 50 mg Current Unavailable Manufacturing 14/10/2025 nebivolol hydrochloride Tablet 1.363 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 14/10/2025 metoprolol succinate Tablet, modified release 23.75 mg Resolved Available Manufacturing 14/10/2025 levothyroxine sodium Tablet 100 microgram Current Unavailable Unexpected increase in consumer demand 14/10/2025 methylphenidate hydrochloride Capsule, modified release 20 mg Current Limited Availability Manufacturing 14/10/2025 methylphenidate hydrochloride Capsule, modified release 30 mg Current Limited Availability Manufacturing 14/10/2025 methylphenidate hydrochloride Capsule, modified release 40 mg Current Unavailable Manufacturing 14/10/2025 phenytoin sodium Injection, solution 250 mg Anticipated Available Manufacturing 13/10/2025 lidocaine hydrochloride Injection, solution 20 mg/mL Resolved Available Manufacturing 13/10/2025 adrenaline (epinephrine) acid tartrate~lidocaine hydrochloride Injection, solution 9.1 microgram/mL~20 mg/mL Resolved Available Manufacturing 13/10/2025 venlafaxine hydrochloride Capsule, modified release 84.86 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 13/10/2025 ethinylestradiol~drospirenone Tablet 30 microgram~3 mg Current Limited Availability Manufacturing 13/10/2025 galantamine hydrobromide Capsule, modified release 10.252 mg Current Unavailable Manufacturing 13/10/2025 milrinone Injection, concentrated 10 mg Current Limited Availability Manufacturing 13/10/2025 irbesartan Tablet, film coated 150 mg Current Unavailable Manufacturing 13/10/2025 montelukast sodium Tablet, chewable 5.2 mg Current Unavailable Manufacturing 13/10/2025 potassium chloride Tablet, modified release 600 mg Resolved Available Manufacturing 13/10/2025 lacosamide Tablet, film coated 100 mg Resolved Available Manufacturing 13/10/2025 phenytoin sodium Injection, solution 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 13/10/2025 bromazepam Tablet, uncoated 6 mg Anticipated Available Transport / Logistic issues / Storage capacity issues 13/10/2025 cisatracurium besilate Injection, solution 2.68 mg/mL Resolved Available Manufacturing 13/10/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated .25 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 13/10/2025 spironolactone Tablet, film coated 25 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 13/10/2025 - 2025.10.13
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated tramadol hydrochloride Capsule 50 mg Resolved Available Manufacturing 10/10/2025 topiramate Tablet, film coated 50 mg Anticipated Available Manufacturing 10/10/2025 ciprofloxacin hydrochloride Tablet, film coated 832.5 mg Anticipated Available Manufacturing 10/10/2025 tetrabenazine Tablet, uncoated 25 mg Resolved Available Manufacturing 10/10/2025 venlafaxine hydrochloride Capsule, modified release 169.71 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 10/10/2025 fosaprepitant dimeglumine Injection, powder for 257.6 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 10/10/2025 temozolomide Capsule, hard 5 mg Current Limited Availability Manufacturing 10/10/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 10/10/2025 galantamine hydrobromide Capsule, modified release 30.756 mg Current Unavailable Manufacturing 10/10/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 10/10/2025 raloxifene hydrochloride Tablet, film coated 60 mg Current Unavailable Manufacturing 10/10/2025 quetiapine fumarate Tablet, film coated 115.12 mg Anticipated Available Commercial Changes / Commercial viability 10/10/2025 quetiapine fumarate Tablet, film coated 345.36 mg Anticipated Available Commercial Changes / Commercial viability 10/10/2025 cisatracurium besilate Injection, solution 7.04 mg Current Limited Availability Manufacturing 10/10/2025 mebeverine hydrochloride Tablet, film coated 135 mg Current Unavailable Manufacturing 10/10/2025 ropinirole hydrochloride Tablet, film coated .285 mg Current Unavailable Manufacturing 10/10/2025 lacosamide Tablet, film coated 150 mg Current Limited Availability Manufacturing 10/10/2025 Trastuzumab Injection, powder for 156 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 10/10/2025 teriflunomide Tablet, film coated 14 mg Current Limited Availability Manufacturing 10/10/2025 rivaroxaban Tablet, film coated 10 mg Anticipated Available Manufacturing 10/10/2025 valaciclovir hydrochloride Tablet, film coated 1112 mg Current Limited Availability Manufacturing 10/10/2025 phenoxymethylpenicillin potassium Oral Liquid, powder for 28.284 mg/mL Current Unavailable Manufacturing 9/10/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Limited Availability Manufacturing 9/10/2025 chloramphenicol Eye Drops 5 mg/mL Resolved Available Manufacturing 9/10/2025 lansoprazole Tablet, orally disintegrating 15 mg Current Unavailable Manufacturing 9/10/2025 desvenlafaxine Tablet, modified release 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 9/10/2025 desvenlafaxine Tablet, modified release 50 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 9/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Unexpected increase in consumer demand 9/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Unexpected increase in consumer demand 9/10/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 9/10/2025 hydrocortisone Tablet, uncoated 4 mg Anticipated Available Manufacturing 9/10/2025 ezetimibe~simvastatin Tablet 10 mg~40 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 9/10/2025 fingolimod hydrochloride Capsule 560 microgram Anticipated Available Manufacturing 9/10/2025 estradiol Drug delivery system, transdermal .39 mg Current Unavailable Manufacturing 9/10/2025 estradiol Drug delivery system, transdermal .78 mg Current Unavailable Manufacturing 9/10/2025 estradiol Drug delivery system, transdermal 1.17 mg Current Unavailable Manufacturing 9/10/2025 estradiol Drug delivery system, transdermal 1.56 mg Current Unavailable Manufacturing 9/10/2025 lenalidomide Capsule 5 mg Current Limited Availability Manufacturing 9/10/2025 bleomycin sulfate Injection, powder for 15000 IU Anticipated Available Manufacturing 9/10/2025 doxorubicin hydrochloride Injection, concentrated 20 mg Resolved Available Manufacturing 9/10/2025 methylphenidate hydrochloride Tablet, modified release 18 mg Current Limited Availability Manufacturing 9/10/2025 methylphenidate hydrochloride Tablet, modified release 36 mg Current Limited Availability Manufacturing 9/10/2025 tranexamic acid Tablet, film coated 500 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 8/10/2025 galantamine hydrobromide Capsule, modified release 30.768 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 8/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 8/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 8/10/2025 valsartan~hydrochlorothiazide Tablet, film coated 320 mg~25 mg Resolved Available Manufacturing 8/10/2025 temozolomide Capsule, hard 20 mg Anticipated Available Manufacturing 8/10/2025 escitalopram oxalate Tablet, film coated 25.548 mg Anticipated Available Manufacturing 8/10/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Unavailable Manufacturing 8/10/2025 anastrozole Tablet, film coated 1 mg Current Limited Availability Manufacturing 8/10/2025 clonidine hydrochloride Tablet 100 microgram Resolved Available Manufacturing 8/10/2025 hydrochlorothiazide~irbesartan Tablet, film coated 12.5 mg~150 mg Current Unavailable Manufacturing 8/10/2025 hydrochlorothiazide~irbesartan Tablet, film coated 25 mg~300 mg Current Unavailable Manufacturing 8/10/2025 metformin hydrochloride Tablet, film coated 1000 mg Current Unavailable Unexpected increase in consumer demand 8/10/2025 Mecasermin Injection, solution 10 mg/mL Resolved Available Unexpected increase in consumer demand 8/10/2025 erlotinib hydrochloride Tablet, film coated 27.32 mg Current Unavailable Unexpected increase in consumer demand 8/10/2025 spironolactone Tablet, uncoated 25 mg Resolved Available Manufacturing 8/10/2025 bortezomib Injection, solution 3.5 mg Resolved Available Manufacturing 8/10/2025 paracetamol Tablet, modified release 665 mg Resolved Available Transport / Logistic issues / Storage capacity issues 8/10/2025 naproxen Tablet, uncoated 250 mg Resolved Available Manufacturing 8/10/2025 tranexamic acid Tablet, film coated 500 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 8/10/2025 trandolapril Capsule, hard 2 mg Resolved Available Manufacturing 8/10/2025 rifampicin Capsule, hard 300 mg Current Unavailable Manufacturing 8/10/2025 clindamycin phosphate Cream 22.8 mg/g Resolved Available Transport / Logistic issues / Storage capacity issues 8/10/2025 paclitaxel Injection, concentrated 6 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 8/10/2025 labetalol hydrochloride Tablet, film coated 100 mg Current Limited Availability Manufacturing 8/10/2025 dosulepin hydrochloride Tablet, film coated 75 mg Current Limited Availability Manufacturing 8/10/2025 metformin hydrochloride Tablet, film coated 1000 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 8/10/2025 acetylcysteine Injection, concentrated 2 g Current Limited Availability Manufacturing 7/10/2025 topiramate Tablet, film coated 25 mg Current Unavailable Manufacturing 7/10/2025 ciprofloxacin hydrochloride Tablet, film coated 277.5 mg Current Unavailable Manufacturing 7/10/2025 acetazolamide sodium Injection, powder for 549.5 mg Current Unavailable Manufacturing 7/10/2025 lamotrigine Tablet, chewable 50 mg Anticipated Available Manufacturing 7/10/2025 lamotrigine Tablet, chewable 100 mg Current Unavailable Manufacturing 7/10/2025 olanzapine Tablet, film coated 5 mg Current Unavailable Manufacturing 7/10/2025 methylphenidate hydrochloride Capsule, modified release 10 mg Current Limited Availability Manufacturing 7/10/2025 levetiracetam Tablet, film coated 500 mg Current Limited Availability Manufacturing 7/10/2025 sildenafil citrate Tablet, film coated 140.45 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 7/10/2025 sulfamethoxazole~trimethoprim Tablet, uncoated 800 mg~160 mg Resolved Available Manufacturing 7/10/2025 exemestane Tablet, sugar coated 25 mg Anticipated Available Manufacturing 7/10/2025 olanzapine Tablet, orally disintegrating 10 mg Anticipated Available Manufacturing 7/10/2025 olanzapine Tablet, orally disintegrating 5 mg Anticipated Available Manufacturing 7/10/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Current Unavailable Manufacturing 7/10/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Anticipated Available Manufacturing 7/10/2025 galantamine hydrobromide Capsule, modified release 10.252 mg Current Unavailable Manufacturing 7/10/2025 galantamine hydrobromide Capsule, modified release 30.756 mg Current Unavailable Manufacturing 7/10/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 7/10/2025 indapamide hemihydrate Tablet, sugar coated 2.5 mg Current Limited Availability Manufacturing 7/10/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 7/10/2025 isotretinoin Capsule, soft 10 mg Current Unavailable Manufacturing 7/10/2025 isotretinoin Capsule, soft 20 mg Current Unavailable Manufacturing 7/10/2025 enalapril maleate Tablet 5 mg Anticipated Available Manufacturing 7/10/2025 phenobarbital Tablet, uncoated 30 mg Anticipated Available Manufacturing 7/10/2025 metformin hydrochloride Tablet, film coated 1000 mg Current Unavailable Manufacturing 7/10/2025 citalopram hydrobromide Tablet, film coated 49.98 mg Resolved Available Manufacturing 7/10/2025 ezetimibe Tablet, uncoated 10 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 7/10/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Manufacturing 7/10/2025 ivabradine hydrochloride Tablet, film coated 8.085 mg Resolved Available Manufacturing 7/10/2025 teriflunomide Tablet, film coated 14 mg Current Unavailable Manufacturing 7/10/2025 pregabalin Capsule, hard 300 mg Anticipated Available Manufacturing 7/10/2025 oseltamivir phosphate Capsule, hard 98.524 mg Current Limited Availability Manufacturing 7/10/2025 sitagliptin hydrochloride monohydrate~metformin hydrochloride Tablet, modified release 56.685 mg~1000 mg Anticipated Available Manufacturing 7/10/2025 Teriparatide Injection, solution .25 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 7/10/2025 Teriparatide Injection, solution 250 microgram/mL Current Unavailable Manufacturing 7/10/2025 minocycline hydrochloride dihydrate Tablet, film coated 54 mg Resolved Available Manufacturing 7/10/2025 olanzapine Injection, powder for 10 mg Resolved Available Unexpected increase in consumer demand 7/10/2025 ciprofloxacin hydrochloride Tablet, film coated 873.32 mg Current Limited Availability Manufacturing 7/10/2025 methylphenidate hydrochloride Capsule, modified release 30 mg Current Limited Availability Manufacturing 7/10/2025 amoxicillin trihydrate Oral Liquid, powder for 28.7 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 6/10/2025 - 2025.10.05
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated trandolapril~verapamil hydrochloride Tablet, film coated 4 mg~240 mg Current Limited Availability Manufacturing 3/10/2025 acetylcholine chloride Solution, powder for irrigation 10 mg/mL Resolved Available Manufacturing 3/10/2025 ramipril Tablet, uncoated 1.25 mg Anticipated Available Manufacturing 3/10/2025 Equine antithymocyte immunoglobulin Injection, solution 50 mg/mL Resolved Available Manufacturing 3/10/2025 bromocriptine mesilate Tablet, uncoated 2.87 mg Resolved Available Manufacturing 3/10/2025 buprenorphine hydrochloride Injection, solution 324 microgram/mL Current Unavailable Manufacturing 3/10/2025 iopromide Injection, solution 498.72 mg/mL Current Unavailable Manufacturing 3/10/2025 silver sulfadiazine Cream 10 mg/g Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 3/10/2025 silver sulfadiazine Cream 10 mg/g Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 3/10/2025 risperidone Tablet, film coated 2 mg Anticipated Available Manufacturing 3/10/2025 pioglitazone hydrochloride Tablet 49.9 mg Anticipated Available Manufacturing 3/10/2025 hydrocortisone sodium succinate Injection, powder for 134 mg Anticipated Available Manufacturing 3/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 3/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Manufacturing 3/10/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 3/10/2025 trandolapril Capsule, hard .5 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 trandolapril Capsule, hard 1 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 trandolapril Capsule, hard 2 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 trandolapril Capsule, hard 4 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 metoprolol succinate Tablet, modified release 95 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 metoprolol succinate Tablet, modified release 47.5 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 metoprolol succinate Tablet, modified release 190 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 metoprolol succinate Tablet, modified release 23.75 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 paclitaxel Injection, concentrated 300 mg Current Unavailable Manufacturing 3/10/2025 adrenaline (epinephrine) acid tartrate~articaine hydrochloride Injection, solution 18.2 microgram/mL~40 mg/mL Resolved Available Transport / Logistic issues / Storage capacity issues 3/10/2025 citalopram hydrobromide Tablet, film coated 12.495 mg Current Limited Availability Manufacturing 3/10/2025 bimatoprost Eye Drops .3 mg/mL Current Unavailable Manufacturing 3/10/2025 methylphenidate hydrochloride Capsule, modified release 60 mg Current Unavailable Manufacturing 3/10/2025 hydrochlorothiazide~irbesartan Tablet, film coated 12.5 mg~300 mg Current Unavailable Manufacturing 3/10/2025 nizatidine Capsule, hard 150 mg Current Unavailable Manufacturing 3/10/2025 ambrisentan Tablet, film coated 10 mg Anticipated Available Manufacturing 3/10/2025 mefenamic acid Capsule, hard 250 mg Current Unavailable Manufacturing 3/10/2025 dabigatran etexilate mesilate Capsule, hard 126.83 mg Current Limited Availability Manufacturing 3/10/2025 posaconazole Tablet, modified release 100 mg Resolved Available Manufacturing 3/10/2025 sacubitril~valsartan Tablet, film coated 48.6 mg~51.4 mg Resolved Available Manufacturing 3/10/2025 valsartan~sacubitril Tablet, film coated 102.8 mg~97.2 mg Resolved Available Manufacturing 3/10/2025 carboplatin Injection, solution 10 mg/mL Resolved Available Unexpected increase in demand due to other sponsors unable to supply 3/10/2025 iotroxate meglumine Injection, solution 105.46 mg/mL Current Unavailable Transport / Logistic issues / Storage capacity issues 3/10/2025 methylphenidate hydrochloride Capsule, modified release 20 mg Current Limited Availability Manufacturing 3/10/2025 methylphenidate hydrochloride Capsule, modified release 40 mg Current Unavailable Manufacturing 3/10/2025 Measles virus~Rubella virus~Mumps virus Injection, powder for 1000 CCID50~1000 CCID50~5000 CCID50 Resolved Available Unexpected increase in consumer demand 3/10/2025 prazosin hydrochloride Tablet, uncoated 1.095 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 2/10/2025 prazosin hydrochloride Tablet, uncoated 5.476 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 2/10/2025 metformin hydrochloride Tablet, film coated 500 mg Current Unavailable Manufacturing 2/10/2025 valsartan~hydrochlorothiazide Tablet, film coated 320 mg~25 mg Current Limited Availability Manufacturing 2/10/2025 risperidone Tablet, film coated .5 mg Current Unavailable Manufacturing 2/10/2025 entecavir Tablet, film coated .5 mg Current Unavailable Manufacturing 2/10/2025 entecavir Tablet, film coated 1 mg Anticipated Available Manufacturing 2/10/2025 Trastuzumab Injection, solution 600 mg Resolved Available Manufacturing 2/10/2025 rosuvastatin calcium Tablet, film coated 20.84 mg Current Limited Availability Unexpected increase in consumer demand 2/10/2025 azacitidine Injection, powder for 100 mg Resolved Available Manufacturing 2/10/2025 tranexamic acid Tablet, film coated 500 mg Current Unavailable Manufacturing 2/10/2025 ambrisentan Tablet, film coated 5 mg Anticipated Available Manufacturing 2/10/2025 deferasirox Tablet, film coated 90 mg Current Limited Availability Manufacturing 2/10/2025 deferasirox Tablet, film coated 360 mg Current Limited Availability Manufacturing 2/10/2025 metoprolol succinate Tablet, modified release 23.75 mg Current Limited Availability Manufacturing 2/10/2025 sitagliptin hydrochloride monohydrate~metformin hydrochloride Tablet, film coated 56.69 mg~1000 mg Resolved Available Manufacturing 2/10/2025 quinagolide hydrochloride Tablet, uncoated .0819 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 2/10/2025 prazosin hydrochloride Tablet, uncoated 1.1 mg Current Unavailable Manufacturing 2/10/2025 sertraline hydrochloride Tablet, film coated 56 mg Current Unavailable Manufacturing 2/10/2025 sertraline hydrochloride Tablet, film coated 112 mg Current Limited Availability Manufacturing 2/10/2025 mirtazapine Tablet, film coated 30 mg Resolved Available Manufacturing 2/10/2025 live varicella vaccine Injection, powder for 2700 PFU/mL Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 1/10/2025 sertraline hydrochloride Tablet, film coated 55.96 mg Current Unavailable Manufacturing 1/10/2025 risperidone Tablet 1 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 1/10/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Current Limited Availability Manufacturing 1/10/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Current Limited Availability Manufacturing 1/10/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Current Unavailable Manufacturing 1/10/2025 ceftaroline fosamil Injection, powder for 600 mg Resolved Available Manufacturing 1/10/2025 clopidogrel hydrogen sulfate~aspirin Tablet 97.87 mg~100 mg Resolved Available Manufacturing 1/10/2025 live varicella vaccine Injection, powder for 4000 PFU/mL Current Only available under NIP or government programs Unexpected increase in consumer demand 1/10/2025 mesalazine Tablet, enteric coated 800 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 1/10/2025 Rabies virus Injection, powder for 2.5 IU Current Emergency Supply Only Unexpected increase in consumer demand 1/10/2025 teriflunomide Tablet, film coated 14 mg Current Limited Availability Manufacturing 1/10/2025 Mecasermin Injection, solution 10 mg/mL Current Limited Availability Unexpected increase in consumer demand 1/10/2025 estradiol~estradiol~norethisterone acetate Drug delivery system, transdermal .78 mg~.62 mg~2.7 mg Resolved Available Manufacturing 1/10/2025 GluureaLys(ahx)hbedCC Injection, powder for 25 microgram Current Unavailable Manufacturing 1/10/2025 tranexamic acid Tablet, film coated 500 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 1/10/2025 rifampicin Capsule, hard 150 mg Current Limited Availability Manufacturing 1/10/2025 lidocaine hydrochloride monohydrate Injection, solution 20 mg/mL Resolved Available Manufacturing 1/10/2025 prazosin hydrochloride Tablet, uncoated 2.2 mg Current Unavailable Manufacturing 1/10/2025 prazosin hydrochloride Tablet, uncoated 5.5 mg Current Unavailable Manufacturing 1/10/2025 primidone Tablet, uncoated 250 mg Current Limited Availability Manufacturing 30/09/2025 lidocaine hydrochloride Gel 20 mg/g Current Limited Availability Manufacturing 30/09/2025 pantoprazole sodium sesquihydrate Tablet, enteric coated 45.4 mg Current Limited Availability Unexpected increase in consumer demand 30/09/2025 midazolam Injection, solution 50 mg Resolved Available Manufacturing 30/09/2025 midazolam Injection, solution 50 mg Current Limited Availability Manufacturing 30/09/2025 docetaxel Injection, concentrated 80 mg Resolved Available Manufacturing 30/09/2025 rosuvastatin calcium Tablet, film coated 41.68 mg Current Limited Availability Manufacturing 30/09/2025 rosuvastatin calcium Tablet, film coated 10.42 mg Current Unavailable Manufacturing 30/09/2025 pregabalin Capsule, hard 75 mg Current Limited Availability Manufacturing 30/09/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Current Unavailable Manufacturing 30/09/2025 dabigatran etexilate mesilate Capsule, hard 172.95 mg Current Unavailable Manufacturing 30/09/2025 oseltamivir phosphate Capsule, hard 98.524 mg Current Limited Availability Manufacturing 30/09/2025 cabazitaxel Injection, concentrated 60 mg Current Limited Availability Manufacturing 30/09/2025 fentanyl citrate Injection, solution 785 microgram Current Unavailable Manufacturing 30/09/2025 ropivacaine hydrochloride Injection, solution 10 mg/mL Current Unavailable Manufacturing 30/09/2025 gefitinib Tablet, film coated 250 mg Discontinued Unavailable Commercial Changes / Commercial viability 30/09/2025 betamethasone valerate Cream 1.21 mg/g Resolved Available Manufacturing 29/09/2025 fludarabine phosphate Injection, powder for 50 mg Current Limited Availability Manufacturing 29/09/2025 finasteride Tablet, film coated 1 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 29/09/2025 sulfamethoxazole~trimethoprim Tablet, uncoated 800 mg~160 mg Current Limited Availability Manufacturing 29/09/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in consumer demand 29/09/2025 chloramphenicol Eye Drops 5 mg/mL Current Unavailable Manufacturing 29/09/2025 phenobarbital Tablet, uncoated 30 mg Anticipated Available Manufacturing 29/09/2025 quetiapine fumarate Tablet, modified release 57.5 mg Anticipated Available Unexpected increase in consumer demand 29/09/2025 irbesartan Tablet, film coated 75 mg Current Limited Availability Manufacturing 29/09/2025 ivabradine hydrochloride Tablet, film coated 5.39 mg Resolved Available Manufacturing 29/09/2025 dimethyl fumarate Capsule, enteric 120 mg Resolved Available Manufacturing 29/09/2025 lurasidone hydrochloride Tablet, film coated 40 mg Current Unavailable Manufacturing 29/09/2025 lurasidone hydrochloride Tablet, film coated 80 mg Current Unavailable Manufacturing 29/09/2025 potassium chloride Tablet, modified release 600 mg Current Limited Availability Manufacturing 29/09/2025 spironolactone Tablet, uncoated 25 mg Current Limited Availability Manufacturing 29/09/2025 tetrabenazine Tablet, uncoated 25 mg Current Unavailable Manufacturing 29/09/2025 lidocaine hydrochloride Injection, solution 10 mg/mL Current Unavailable Manufacturing 29/09/2025 cisatracurium besilate Injection, solution 2.68 mg/mL Current Unavailable Manufacturing 29/09/2025 olanzapine Tablet, film coated 5 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 29/09/2025 olanzapine Wafer 5 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 29/09/2025
ドイツ
- 2025.10.27
Active ingredients Message type Date of last message Type of reason AM designation Beclometasone dipropionate (Ph.Eur.) Initial report 24.10.2025 Other Beclorhinol aquosum 50 micrograms Rifampicin sodium Change notification 24.10.2025 Other Eremfat i.v. 600mg Nimodipine Initial report 24.10.2025 Other Nimodipine Hexal 30 mg Mivacurium chloride Change notification 23.10.2025 Production problem Mivacron 10mg Lorazepam Change notification 23.10.2025 Other Tavor 2.5 mg Expidet Quetiapine fumarate (Ph.Eur.) Change notification 23.10.2025 Other Quetiapine Hormosan 150 mg prolonged-release tablets Misoprostol Initial report 23.10.2025 Other Angusta 25 microgram tablets Epoetin beta Change notification 23.10.2025 Other NeoRecormon 5000 IU solution for injection in pre-filled syringe – OP6 Epoetin beta Change notification 23.10.2025 Other NeoRecormon 3000 IU solution for injection in pre-filled syringe – OP6 Epoetin beta Change notification 23.10.2025 Other NeoRecormon 4000 IU solution for injection in pre-filled syringe – OP6 Epoetin beta Change notification 23.10.2025 Other NeoRecormon 2000 IU solution for injection in pre-filled syringe – OP6 Insulin lispro Initial report 23.10.2025 Other Liprolog Mix25 100 IU/ml KwikPen injection suspension – OP[2x(5x3ml)] Thiamazole Initial report 22.10.2025 Other Thiamazole 5mg Henning Acetylcholine chloride Change notification 22.10.2025 Production problem Miochol-E Powder and solvent for the preparation of an instillation solution for intraocular use Thiamazole Initial report 22.10.2025 Other Thiamazole 20 mg Henning Quetiapine fumarate (Ph.Eur.) Initial report 22.10.2025 Production problem Quetiapine Accord 400 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Initial report 22.10.2025 Production problem Quetiapine Accord 200 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Initial report 22.10.2025 Production problem Quetiapine Accord 150 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 22.10.2025 Production problem Quetiapine Accord 50 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 22.10.2025 Production problem Quetiapine Accord 300 mg prolonged-release tablets Insulin glargine Change notification 22.10.2025 Other Semglee Pirfenidone Change notification 22.10.2025 Production problem Pirfenidone Accord 801 mg film-coated tablets Amikacin sulfate Change notification 22.10.2025 Production problem Amikacin B. Braun 5 mg/ml solution for infusion Amikacin sulfate Change notification 22.10.2025 Production problem Amikacin B. Braun 2.5 mg/ml solution for infusion Flutamide Initial report 22.10.2025 Other Flutamide AL 250 Carbamazepine Initial report 21.10.2025 Other Timonil Syrup Tinzaparin sodium Initial report 21.10.2025 Production problem innohep 20,000 Anti-Xa I.E./ml Vials Solution for injection Methylphenidate hydrochloride Change notification 21.10.2025 Other Equasym Retard 40 mg modified-release hard capsules Methyldopa (Ph.Eur.) Initial report 21.10.2025 Other Dopegyt tablets Ibuprofen Change notification 21.10.2025 Other IBU-PUREN acute 400 mg film-coated tablets Carbamazepine Change notification 21.10.2025 Other Carbadura 400 mg retard Methylphenidate hydrochloride Change notification 20.10.2025 Other METHYLPHENIDATE 20 mg tablets Human insulin (with manufacturing details) Initial report 20.10.2025 Other Berlinsulin H 30/70 3 ml pen Isotretinoin Initial report 20.10.2025 Other ISOTRETINOIN BASICS 10 mg soft capsules Fampridine Change notification 20.10.2025 Other FAMPRIDIN BASICS 10 mg prolonged-release tablets Pramipexole dihydrochloride monohydrate Change notification 20.10.2025 Other Pramipexole Mylan 0.26 mg prolonged-release tablets Pramipexole dihydrochloride monohydrate Change notification 20.10.2025 Other Pramipexole Mylan 0.52 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Initial report 20.10.2025 Other Seroquel Prolong 300 mg prolonged-release tablets Sodium (hydrocortisone-21-succinate) Change notification 20.10.2025 Production problem Hydrocortisone PANPHARMA 250 mg - 2025.10.20
Active ingredients Message type Date of last message Type of reason AM designation Lidocaine hydrochloride monohydrate Change notification 17.10.2025 Other Xylocaine Gel 2% Estriol Initial report 17.10.2025 Other Ovestin 1 mg cream Mivacurium chloride Initial report 17.10.2025 Other Mivacron 10 mg Lidocaine Initial report 17.10.2025 Other XYLOCAIN PUMP SPRAY dental Salbutamol sulfate Change notification 17.10.2025 Other Sultanol forte ready-to-use inhalation solution Levothyroxine sodium Initial report 17.10.2025 Production problem L-thyroxine Henning 50 Levothyroxine sodium Initial report 17.10.2025 Production problem L-thyroxine Henning 125 Levothyroxine sodium Initial report 17.10.2025 Production problem L-Thyroxine Henning 75 Gentamicin sulfate Initial report 17.10.2025 Production problem Gentamicin-POS Phenylephrine hydrochloride Change notification 17.10.2025 Production problem Neosynephrine-POS 5% Fampridine Change notification 17.10.2025 Other FAMPRIDIN BASICS 10 mg prolonged-release tablets Atorvastatin calcium trihydrate (Ph.Eur.) Initial report 17.10.2025 Other ATORVASTATIN BASICS 80 mg film-coated tablets Olanzapine embonate monohydrate Initial report 17.10.2025 Other ZYPADHERA 405 mg powder and solvent for the preparation of a prolonged-release injection suspension – OP(931mg+3ml) Candesartan cilexetil Initial report 17.10.2025 Other ATACAND 16 mg Olanzapine embonate monohydrate Change notification 17.10.2025 Production problem ZYPADHERA 210 mg powder and solvent for the preparation of a prolonged-release suspension for injection – OP(483mg+3ml) Methyldopa (Ph.Eur.) Initial report 17.10.2025 Production problem Presinol 250 Insulin detemir Initial report 17.10.2025 Other Levemir 100 IU solution for injection in pre-filled pen – OP(10x3ml)(FlexPen) Insulin detemir Initial report 17.10.2025 Other Levemir 100 IU injection solution in cartridge – OP(10x3ml) Betamethasone dipropionate (Ph.Eur.); gentamicin sulfate Initial report 16.10.2025 Other Diprogenta Posaconazole Initial report 16.10.2025 Other Posaconazole HEXAL 40 mg/ml oral suspension Oxytocin Initial report 16.10.2025 Production problem Oxytocin 3 IU Hexal Human insulin (with manufacturing details) Initial report 16.10.2025 Other Berlinsulin H Basal 3 ml pen Insulin aspart Change notification 16.10.2025 Other NovoMix 30 FlexPen 100 IU/ml injection suspension in pre-filled syringe – OP(10x3ml) Human insulin (with manufacturing details) Initial report 15.10.2025 Other Berlinsulin H Normal 3 ml pen Methylprednisolone Initial report 15.10.2025 Other Methylprednisolone 4mg JENAPHARM Azithromycin dihydrate Change notification 15.10.2025 Other Azithromycin AL 250 mg film-coated tablets Vancomycin hydrochloride Change notification 15.10.2025 Production problem Vancomycin Lyomark 500 mg Vancomycin hydrochloride Change notification 15.10.2025 Production problem Vancomycin Lyomark 1000 mg powder for concentrate for solution for infusion or oral solution Posaconazole Initial report 15.10.2025 Other Posaconazole AL 40 mg/ml oral suspension Methylphenidate hydrochloride Initial report 15.10.2025 Other Metiphenal 10 mg modified-release hard capsules Folic acid hydrate (with information on water content (1:x)) Initial report 15.10.2025 Other Folic acid AL 5 mg tablets Acitretin Initial report 15.10.2025 Other Acicutan 25 mg hard capsules Fusidic acid (Ph.Eur.) Initial report 15.10.2025 Other Fusicutan ointment Oxazepam Initial report 15.10.2025 Other Durazepam 50 mg forte Oxycodone hydrochloride (Ph.Eur.) Initial report 14.10.2025 Production problem Oxygesic Dispersa acute 5 mg Oxycodone hydrochloride (Ph.Eur.) Initial report 14.10.2025 Production problem Oxygesic Dispersa acute 10 mg Oxycodone hydrochloride Change notification 14.10.2025 Other OXYGESIC 10 mg Arsenic(III) oxide Initial report 14.10.2025 Other TRISENOX 2 mg/ml concentrate for solution for infusion Granisetron hydrochloride Initial report 14.10.2025 Other Kevatril 3 mg/3 ml solution for injection Carboplatin Initial report 14.10.2025 Other Carboplatin Kabi 10 mg/ml concentrate for solution for infusion Dexketoprofen trometamol Initial report 14.10.2025 Production problem Sympal inject 50 mg injection/infusion solution Tolterodine tartrate Initial report 14.10.2025 Other Detrusitol 2 mg film-coated tablets Doxepin hydrochloride (Ph.Eur.) Initial report 14.10.2025 Other Doxepin-ratiopharm 50 mg film-coated tablets Doxepin hydrochloride (Ph.Eur.) Initial report 14.10.2025 Other Doxepin-ratiopharm 25 mg film-coated tablets Thiamazole Initial report 13.10.2025 Other Thiamazole 5 mg Henning Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y) Change notification 13.10.2025 Other Ferrlecit 62.5 mg Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y) Change notification 13.10.2025 Other Ferrlecit 40 mg Cisatracurium besylate Change notification 13.10.2025 Other Nimbex 10 mg Zolbetuximab Change notification 13.10.2025 Other Vyloy Paliperidone palmitate Initial report 13.10.2025 Other XEPLION 50 mg prolonged-release suspension for injection – OP1ml - 2025.10.13
Active ingredients Message type Date of last message Type of reason AM designation Tinzaparin sodium Change notification 10.10.2025 Production problem innohep 4,500 Anti-Xa I.E. Solution for injection Carbamazepine Initial report 09.10.2025 Production problem Carbamazepine Aristo 600 mg prolonged-release tablets Carbamazepine Initial report 09.10.2025 Production problem Carbamazepine Aristo 300 mg prolonged-release tablets Ezetimibe; simvastatin Change notification 09.10.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/80 mg tablets Ezetimibe; simvastatin Change notification 09.10.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/40 mg tablets Ezetimibe; simvastatin Change notification 09.10.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/20 mg tablets Ezetimibe; simvastatin Change notification 09.10.2025 Production problem EZETIMIBE/SIMVA BASICS 10 mg/10 mg tablets Esomeprazole hemimagnesium Change notification 09.10.2025 Production problem ESOMEPRAZOLE BASICS 40 mg gastro-resistant hard capsules Esomeprazole hemimagnesium Change notification 09.10.2025 Production problem ESOMEPRAZOLE BASICS 20 mg gastro-resistant hard capsules Moxifloxacin hydrochloride (Ph.Eur.) ((with information on water content (1:x))) Initial report 09.10.2025 Other Moxifloxacin Holsten 400 mg film-coated tablets Leflunomide Initial report 09.10.2025 Other Leflunomide Bluefish 20 mg film-coated tablets Methylphenidate hydrochloride Change notification 09.10.2025 Other METHYLPHENIDATE 20 mg tablets Methylphenidate hydrochloride Change notification 09.10.2025 Other METHYLPHENIDATE 5 mg tablets Leflunomide Initial report 09.10.2025 Other Leflunomide Bluefish 10 mg film-coated tablets Potassium canrenoate Change notification 09.10.2025 Production problem Aldactone 10 ml Canrenoate Urapidil Initial report 09.10.2025 Production problem Urapidil Bluefish 90 mg hard capsules, delayed release Urapidil Initial report 09.10.2025 Production problem Urapidil Bluefish 30 mg hard capsules, delayed release Methylphenidate hydrochloride Change notification 09.10.2025 Other Methylphenidate-ratiopharm 40 mg hard capsules with modified release Primidone Change notification 09.10.2025 Production problem Mylepsinum Quetiapine fumarate (Ph.Eur.) Change notification 09.10.2025 Other Quetiapine AbZ 150 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 09.10.2025 Other Quetiapine-ratiopharm 300 mg prolonged-release tablets Risperidone Change notification 09.10.2025 Production problem Risperidone-ratiopharm 25 mg powder and solvent for the preparation of a depot injection suspension Risperidone Change notification 09.10.2025 Production problem Risperidone-ratiopharm 37.5 mg powder and solvent for the preparation of a depot injection suspension Risperidone Change notification 09.10.2025 Production problem Risperidone-ratiopharm 50 mg powder and solvent for the preparation of a depot injection suspension Pramipexole dihydrochloride monohydrate Change notification 09.10.2025 Other Pramipexole-ratiopharm 0.52 mg prolonged-release tablets Pramipexole dihydrochloride monohydrate Change notification 09.10.2025 Other Pramipexole-ratiopharm 0.26 mg prolonged-release tablets Carbamazepine Change notification 09.10.2025 Other Carbamazepine-ratiopharm 400 mg prolonged-release tablets Carbamazepine Change notification 09.10.2025 Other Carbamazepine-ratiopharm 200 mg prolonged-release tablets Ribavirin Change notification 09.10.2025 Other Ribavirin-ratiopharm 400 mg film-coated tablets Ribavirin Change notification 09.10.2025 Other Ribavirin-ratiopharm 200 mg film-coated tablets Salbutamol sulfate Initial report 09.10.2025 Other Sultanol metered-dose inhaler Aprepitant Change notification 09.10.2025 Production problem Aprepitant STADA 125 mg hard capsules Human insulin (with manufacturing details); isophane insulin suspension for injection (Ph.Eur.) Change notification 08.10.2025 Other Actraphane 30 FlexPen 100 IU/ml injection suspension in injector – OP(10x3ml) Isophane insulin suspension for injection (Ph.Eur.) Change notification 08.10.2025 Other Protaphane FlexPen 100 IU/ml injection suspension in injector – OP(10x3ml) Nitrendipine Change notification 08.10.2025 Other Nitrendipine AL 20 Aprepitant Change notification 08.10.2025 Other Aprepitant AL 125 mg hard capsules Oxazepam Change notification 08.10.2025 Other Oxazepam AL 10 Quetiapine fumarate (Ph.Eur.) Change notification 08.10.2025 Other Quetiapine AL 50 mg prolonged-release tablets Amoxicillin trihydrate Change notification 08.10.2025 Other Amoxicillin AL TS Doxepin hydrochloride (Ph.Eur.) Change notification 07.10.2025 Production problem Doxepin 25 Holsten Azithromycin dihydrate Change notification 07.10.2025 Other Azithromycin AL 250 mg film-coated tablets Lacosamide Initial report 07.10.2025 Production problem Lacosamide UCB 10 mg/ml syrup Aprepitant Change notification 07.10.2025 Production problem Aprepitant beta 80 mg hard capsules Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Production problem Quetiapine beta 50 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Production problem Quetiapine beta 300 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Production problem Quetiapine beta 200 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Production problem Quetiapine beta 150 mg prolonged-release tablets Atomoxetine hydrochloride Change notification 07.10.2025 Production problem Atomoxetine beta 80 mg hard capsules Aprepitant Change notification 07.10.2025 Production problem Aprepitant beta 125 mg and 80 mg hard capsules Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Other Seroquel Prolong 200 mg prolonged-release tablets Amlodipine besylate; Perindopril tert-butylamine Change notification 07.10.2025 Other Perindopril/amlodipine Denk 4 mg/5 mg tablets Amlodipine besylate; Perindopril tert-butylamine Change notification 07.10.2025 Other Perindopril/amlodipine Denk 4 mg/10 mg tablets Amlodipine besylate; Perindopril tert-butylamine Change notification 07.10.2025 Other Perindopril/Amlodipine Denk 8 mg/10 mg tablets Clopidogrel besylate Change notification 07.10.2025 Other Clopidogrel Denk 75 mg film-coated tablets Methylphenidate hydrochloride Change notification 07.10.2025 Other Methylphenidate AL 36 mg prolonged-release tablets Methylphenidate hydrochloride Change notification 07.10.2025 Other Methylphenidate AL 27 mg prolonged-release tablets Epirubicin hydrochloride Change notification 07.10.2025 Production problem Epirubicin Hikma 2 mg/ml concentrate for solution for infusion Trimipramine mesylate Change notification 06.10.2025 Other Trimipramine – 1 A Pharma 40 mg/ml oral drops, solution Tenofovir disoproxil Initial report 06.10.2025 Other Tenofovir disoproxil Viatris 245 mg film-coated tablets – OP30 Tenofovir disoproxil Change notification 06.10.2025 Other Tenofovir disoproxil Mylan 245 mg film-coated tablets – OP90(3×30) Imiquimod Change notification 06.10.2025 Production problem Aldara 5% cream – OP24 Dacarbazine citrate Change notification 06.10.2025 Other Dacarbazine Lipomed 500 mg powder for solution for infusion Prednisolone acetate Change notification 06.10.2025 Production problem Prednifluid 10 mg/ml eye drop suspension Sevelamer Change notification 06.10.2025 Other Renagel 800 mg film-coated tablets – OP(1×180) Methylphenidate hydrochloride Change notification 06.10.2025 Other Methylphenidate hydrochloride-neuraxpharm 27 mg prolonged-release tablets Phenylephrine hydrochloride Change notification 06.10.2025 Production problem Neosynephrine-POS 10% Gentamicin sulfate Change notification 06.10.2025 Production problem Gentamicin-POS Beclometasone dipropionate (Ph.Eur.) Change notification 06.10.2025 Other Beclorhinol aquosum 50 micrograms - 2025.10.05
Active ingredients Message type Date of last message Type of reason AM designation Enalapril maleate; hydrochlorothiazide Change notification 03.10.2025 Production problem Renacor Methyldopa (Ph.Eur.) Initial report 03.10.2025 Production problem Presinol 500 Cefaclor monohydrate Change notification 02.10.2025 Other Cefaclor 125 TS – 1 A Pharma Cefpodoxime proxetil Initial report 02.10.2025 Other Cefpodoxime – 1 A Pharma 40 mg/5 ml powder for oral suspension Morphine hemisulfate 2.5 hydrate Initial report 02.10.2025 Production problem Substitol 30 mg hard capsules, delayed release Oxycodone hydrochloride (Ph.Eur.) Change notification 02.10.2025 Production problem Oxygesic 5 mg Rifampicin Change notification 02.10.2025 Other EREMFAT 150 mg Oxycodone hydrochloride Change notification 02.10.2025 Other OXYGESIC 10 mg Pyrazinamide Initial report 02.10.2025 Production problem Pyrafat 500 mg Azithromycin dihydrate Change notification 02.10.2025 Other Azithromycin AL 250 mg film-coated tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 200 mg prolonged-release tablets Calcium acetate hydrate (with information on water content (1:x)) Initial report 01.10.2025 Production problem Calcium acetate-Nefro 950mg Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 150 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 50 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 400 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 300 mg prolonged-release tablets Vinorelbine tartrate Initial report 01.10.2025 Production problem Bendarelbin 10 mg/ml concentrate for solution for infusion Sodium perchlorate 1 H<2>O Change notification 30.09.2025 Other Irenat drops Galantamine hydrobromide Change notification 30.09.2025 Production problem Galantamine Heumann 8 mg hard capsules, delayed release Galantamine hydrobromide Change notification 30.09.2025 Production problem Galantamine Heumann 16 mg hard capsules, delayed release Galantamine hydrobromide Change notification 30.09.2025 Production problem Galantamine Heumann 24 mg hard capsules, delayed release Clomethiazole hemidisilate Change notification 30.09.2025 Other Distraneurin mixture Pramipexole dihydrochloride monohydrate Change notification 30.09.2025 Other Pramipexole HEXAL 0.26 mg prolonged-release tablets Pramipexole dihydrochloride monohydrate Change notification 30.09.2025 Other Pramipexole HEXAL 0.52 mg prolonged-release tablets Phenoxymethylpenicillin potassium Change notification 30.09.2025 Other Pen Mega – 1 A Pharma Rifampicin sodium Initial report 30.09.2025 Other Eremfat i.v. 600mg Ascorbic acid; biotin; cholecalciferol; cyanocobalamin; dexpanthenol; folic acid hydrate ((with information on water content (1:x))); Nicotinamide; pyridoxine hydrochloride; retinol palmitate; riboflavin phosphate sodium; thiamine hydrochloride; all-rac-phytomenadione; all-rac-alpha-tocopherol Initial report 30.09.2025 Production problem Viant powder for solution for infusion Tropicamide Change notification 30.09.2025 Production problem Mydriaticum Stulln UD Ipratropium bromide (Ph.Eur.); salbutamol sulfate Change notification 30.09.2025 Production problem COMBIPRASAL 0.5 mg / 2.5 mg solution for nebulizer Ipratropium bromide Change notification 30.09.2025 Production problem Ipratropium bromide 250 micrograms / 1 ml Stulln Paliperidone palmitate Change notification 30.09.2025 Other Paliperidone AL 25 mg depot injection suspension in a pre-filled syringe Methylphenidate hydrochloride Change notification 30.09.2025 Other Methylphenidate AL 36 mg prolonged-release tablets Paliperidone palmitate Change notification 30.09.2025 Other Paliperidone AL 50 mg Depot injection suspension in a pre-filled syringe Beclomethasone dipropionate (Ph.Eur.) Change notification 29.09.2025 Other Beclorhinol aquosum 50 micrograms Insulin glargine Change notification 29.09.2025 Other Semglee 100 units/ml injection solution in pre-filled pen – OP(5x3ml) Insulin glargine Change notification 29.09.2025 Other Semglee Methylphenidate hydrochloride Initial report 29.09.2025 Other Equasym Retard 40 mg hard capsules with modified release
フランス
- 2025.10.27
Active ingredients Statut Update Specialty Synthetic vitamin A concentrate, oily form Marketing discontinuation 24/10/2025 Vitamin A Dulcis 25,000 I.U. per 100 g, ophthalmic ointment bumetanide Return to availability 24/10/2025 Burinex 2 mg/4 ml IV, solution for injection in ampoule methylphenidate hydrochloride Stock shortage 23/10/2025 Concerta LP, extendedrelease tablet paclitaxel Supply tension 23/10/2025 Paclitaxel AHCL 6 mg/ml, dilutable solution for infusion 50 ml and 100 ml vials lithium (carbonate of) Supply tension 23/10/2025 Teralithe 250 mg, scored tablet venlafaxine Supply tension 23/10/2025 Specialties based on Venlafaxine LP 37.5 mg and LP 75 mg sustainedrelease capsules carbamazepine Return to availability 23/10/2025 Carbamazepine Viatris L.P. 200 mg, scored sustainedrelease tablet carbamazepine Return to availability 23/10/2025 Carbamazepine Viatris L.P. 400 mg, scored sustainedrelease tablet chlorpromazine (hydrochloride) Stock shortage 22/10/2025 Largactil 100 mg, scored filmcoated tablet fluorouracil Supply tension 21/10/2025 Fluorouracil Accord 50 mg/ml, solution for diluted infusion, 5 ml and 100 ml bottles fluorouracil Stock shortage 21/10/2025 Fluorouracil Pfizer 50 mg/ml, dilutable solution for infusion 20 ml and 100 ml bottle mitomycin Supply tension 21/10/2025 Mitomycin Accord 20 mg, powder for solution for injection / infusion or intravesical use varenicline (tartrate) Stock shortage 20/10/2025 Champix 0.5 mg and 1 mg, filmcoated tablet liothyronine sodium Supply tension 20/10/2025 Cynomel 0.025 mg, scored tablet emtricitabine/tenofovir disoproxil Return to availability 20/10/2025 Speciality based on emtricitabine/tenofovir disoproxil 200 mg/245 mg, filmcoated tablet - 2025.10.20
Active ingredients Statut Update Specialty digoxine Supply tension 10/17/2025 Digoxine Nativelle 5 µg/0.1 ml, solution buvable en gouttes pyrantel (embonate of) Supply tension 10/17/2025 Combantrin 125 mg, tablet rifamycin sodium Supply tension 10/17/2025 Rifamycin Chibret 1000 000 IU per cent, eye drops solution risperidone Supply tension 10/17/2025 Risperidone 0.5 mg, 1 mg, 2 mg and 3 mg orodispersible tablet risperidone Out of stock 10/17/2025 Risperidone 4 mg Orodispersible tablet olipudase alfa Supply tension 15/10/2025 Xenpozyme 20 mg, powder for solution to be diluted for infusion pertuzumab/trastuzumab Out of stock 15/10/2025 Phesgo 1200 mg/600 mg, solution injectable risperidone Out of stock 15/10/2025 RisperdalConsta L.P. 37.5 mg/2 ml, powder and solvent for prolongedrelease suspension for injection in prefilled syringe risperidone Supply tension 15/10/2025 RisperdalConsta L.P. 50 mg/2 ml and 25 mg/2 ml, powder and solvent for prolongedrelease suspension for injection in prefilled syringe risperidone Out of stock 15/10/2025 Risperidone L.P. 25 mg/2 ml, 37.5 mg/2 ml and 50 mg/2 ml, powder and solvent for prolongedrelease suspension for injection in prefilled syringe lenalidomide Out of stock 15/10/2025 Lenalidomide Mylan, capsule dipyridamole Supply tension 15/10/2025 Persantine 10 mg/2 mL, solution injectable, ampoule chlorpromazine (hydrochloride) Supply tension 13/10/2025 Largactil 25 mg, filmcoated tablet VaricellaZoster Virus (VZV) glycoprotein E antigen (recombinant, adjuvanted) (mammalian/hamster/CHO cells) Supply tension 13/10/2025 Shingrix, powder and suspension for injectable suspension. Varicella zoster vaccine (recombinant, adjuvanted) esketamine (hydrochloride) Return to availability 13/10/2025 Eskesia 5 mg/mL, solution for injection/infusion 10 glass ampoule(s) of 5 ml - 2025.10.13
Active ingredients Statut Update Specialty betamethasone (dipropionate), betamethasone (sodium phosphate) Supply tension 09/10/2025 Diprostene, suspension for injection in pre-filled syringe pancreas powder Supply tension 08/10/2025 Eurobiol 40 000 U, gastroresistant capsule liothyronine sodium Supply tension 07/10/2025 Cynomel 0.025 mg, scored tablet furosemide Marketing discontinuation 06/10/2025 Lasilix Retard 60 mg, capsule peginterferon alfa-2a Return to availability 06/10/2025 Pegasys 90 micrograms, 135 micrograms and 180 micrograms solution for injection in prefilled syringes - 2025.10.05
Active ingredients Statut Update Specialty tranexamic acid Return to availability 03/10/2025 Exacyl 500 mg, film-coated tablet chlorpromazine (hydrochloride) Out of stock 03/10/2025 Largactil 100 mg, scored film-coated tablet praziquantel Out of stock 02/10/2025 Biltricide 600 mg, film-coated quadrisectible tablet fluorouracil Out of stock 02/10/2025 Fluorouracil Pfizer 50 mg/ml, dilutable solution for infusion20 ml and 100 ml bottle atropine (sulfate) Supply tension 02/10/2025 Atropine 0.3%, eye drops Immunoglobulin normal human (IgG) Supply tension 01/10/2025 Immunoglobulin normal human IV and SC (based on) propofol Out of stock 29/09/2025 Diprivan 10 mg/mL, emulsion for injection in pre-filled syringe propofol Supply tension 29/09/2025 Diprivan 20 mg/mL, emulsion for injection in pre-filled syringe
英国
- 2025.10.28
Medicine supply notification: Amiodarone 100mg and 200mg tablets
Amiodarone 100mg and 200mg tablets are in limited supply until the week commencing 17 November 2025. Amiodarone suspension remains available (specials), and unlicensed imports of amiodarone of 100mg and 200mg tablets have been sourced (lead times vary).
Source: Community Pharmacy England
Medicine supply notification: Antimicrobial agents used in tuberculosis (TB) treatment
Following the national patient safety alert issued on 29 July 2025, the supply situation for antimicrobial medicines used to treat tuberculosis has significantly improved, and updated information in this medicines supply notification supersedes the alert.
Source: Community Pharmacy England
Mometasone (Asmanex Twisthaler®) dry powder inhalers are being discontinued (200 microgram per dose, 60 dose from Oct 2025; 200 microgram per dose 60 dose and 400 microgram per dose 30 and 60 dose from Feb 2026). Alternative corticosteroid inhalers are can bridge supply gap.
Source: Community Pharmacy England
SSPs for cefalexin oral suspensions sugar free further extended
SSPs for cefalexin 125mg/5ml oral suspension sugar free (SSP077) and cefalexin 250mg/5ml oral suspension sugar free (SSP078) were due to expire on 24 October 2025 but they have now been further extended to Friday 28 November 2025.
Source: Community Pharmacy England
- 2025.10.21
Medicine supply notification: Dalivit® oral drops
Dalivit® oral drops are out of stock until further notice. Abidec® multivitamin drops remain available and can support increased demand, but as it contains arachis oil (peanut oil), it should not be taken by patients with peanut or soya allergy.
Medicine supply notification: Exenatide (Bydureon® BCise®) 2mg/0.85ml prolonged-release suspension for injection pre-filled pen
Exenatide (Bydureon® BCise®) 2mg/0.85ml prolonged-release suspension for injection pre-filled pens have been discontinued with supplies now exhausted. Alternative GLP-1 RAs and dual GIP/GLP-1 RA remain available and can support increased demand.
EU
EUの情報はありません。