更新された供給不足状況を示しています。
ある時点での供給不足の全体的状況は「供給関連情報」に定期的にアップします。
米国
- 2025.10.13
Generic Name Shortage Status Revision Date Rocuronium Injection Current Shortages 9-Oct-25 Budesonide Suspension for Inhalation Current Shortages 7-Oct-25 Difluprednate Ophthalmic Emulsion Current Shortages 7-Oct-25 Magnesium Sulfate Injection Current Shortages 7-Oct-25 Oseltamivir Oral Suspension and Capsules Current Shortages 7-Oct-25 Remifentanil Injection Current Shortages 7-Oct-25 Triamcinolone Acetonide Injectable Suspension Current Shortages 7-Oct-25 Bupivacaine Injection Current Shortages 6-Oct-25 Dulaglutide Injection Current Shortages 6-Oct-25 Leucovorin Calcium Injection Current Shortages 6-Oct-25 Lidocaine Hydrochloride Oral Topical Solution (Viscous) 2% Current Shortages 6-Oct-25 Mometasone Furoate and Formoterol Fumarate Inhalation Aerosol Current Shortages 6-Oct-25 Oxycodone Hydrochloride and Acetaminophen Tablets Current Shortages 6-Oct-25 Paricalcitol Capsules Current Shortages 6-Oct-25 Sodium Bicarbonate Injection Current Shortages 6-Oct-25 Vancomycin Hydrochloride Injection Current Shortages 6-Oct-25 - 2025.10.13
New
October 10, 2025
- Pemetrexed Disodium Injection (Discontinuation)
October 09, 2025
- Adalimumab-afzb Injection (Discontinuation)
- Hydrocortisone Sodium Succinate Injection (Currently in Shortage)
- Omeprazole Delayed Release Capsule (Discontinuation)
October 07, 2025
- Cobicistat Tablet (Discontinuation)
- Paricalcitol Capsule (Discontinuation)
Updatede
October 09, 2025
- Dexmedetomidine Hydrochloride Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
October 08, 2025
- Azacitidine Injection (Currently in Shortage)
- Bupivacaine Hydrochloride Injection (Currently in Shortage)
- Carboplatin Injection (Currently in Shortage)
- Dexamethasone Sodium Phosphate Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Penicillin G Benzathine Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Ropivacaine Hydrochloride Injection (Currently in Shortage)
October 06, 2025
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- 2025.10.05
- 2025.10.05
New
October 01, 2025
- Hydrochlorothiazide; Quinapril Hydrochloride Tablet (Discontinuation)
- Quinapril Hydrochloride Tablet (Discontinuation)
September 30, 2025
- Oseltamivir Phosphate Capsule (Discontinuation)
September 29, 2025
- Fondaparinux Sodium Injection (Discontinuation)
- Tafamidis Meglumine Capsule (Discontinuation)
- Triazolam Tablet (Discontinuation)
Updated
October 03, 2025
- Lactated Ringers Injection (Resolved)
- Lactated Ringers Injection (Discontinuation)
October 02, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Azacitidine Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methylphenidate Film, Extended Release (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
October 01, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Currently in Shortage)
- Epinephrine Bitartrate, Lidocaine Hydrochloride Injection (Currently in Shortage)
- Fentanyl Citrate Injection (Currently in Shortage)
- Heparin Sodium Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Naltrexone Hydrochloride Tablet (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
September 29, 2025
- Desmopressin Acetate Spray (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Metronidazole Injection (Currently in Shortage)
カナダ
カナダの情報はありません。
オーストラリア
- 2025.10.13
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated tramadol hydrochloride Capsule 50 mg Resolved Available Manufacturing 10/10/2025 topiramate Tablet, film coated 50 mg Anticipated Available Manufacturing 10/10/2025 ciprofloxacin hydrochloride Tablet, film coated 832.5 mg Anticipated Available Manufacturing 10/10/2025 tetrabenazine Tablet, uncoated 25 mg Resolved Available Manufacturing 10/10/2025 venlafaxine hydrochloride Capsule, modified release 169.71 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 10/10/2025 fosaprepitant dimeglumine Injection, powder for 257.6 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 10/10/2025 temozolomide Capsule, hard 5 mg Current Limited Availability Manufacturing 10/10/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 10/10/2025 galantamine hydrobromide Capsule, modified release 30.756 mg Current Unavailable Manufacturing 10/10/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 10/10/2025 raloxifene hydrochloride Tablet, film coated 60 mg Current Unavailable Manufacturing 10/10/2025 quetiapine fumarate Tablet, film coated 115.12 mg Anticipated Available Commercial Changes / Commercial viability 10/10/2025 quetiapine fumarate Tablet, film coated 345.36 mg Anticipated Available Commercial Changes / Commercial viability 10/10/2025 cisatracurium besilate Injection, solution 7.04 mg Current Limited Availability Manufacturing 10/10/2025 mebeverine hydrochloride Tablet, film coated 135 mg Current Unavailable Manufacturing 10/10/2025 ropinirole hydrochloride Tablet, film coated .285 mg Current Unavailable Manufacturing 10/10/2025 lacosamide Tablet, film coated 150 mg Current Limited Availability Manufacturing 10/10/2025 Trastuzumab Injection, powder for 156 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 10/10/2025 teriflunomide Tablet, film coated 14 mg Current Limited Availability Manufacturing 10/10/2025 rivaroxaban Tablet, film coated 10 mg Anticipated Available Manufacturing 10/10/2025 valaciclovir hydrochloride Tablet, film coated 1112 mg Current Limited Availability Manufacturing 10/10/2025 phenoxymethylpenicillin potassium Oral Liquid, powder for 28.284 mg/mL Current Unavailable Manufacturing 9/10/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Limited Availability Manufacturing 9/10/2025 chloramphenicol Eye Drops 5 mg/mL Resolved Available Manufacturing 9/10/2025 lansoprazole Tablet, orally disintegrating 15 mg Current Unavailable Manufacturing 9/10/2025 desvenlafaxine Tablet, modified release 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 9/10/2025 desvenlafaxine Tablet, modified release 50 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 9/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Unexpected increase in consumer demand 9/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Unexpected increase in consumer demand 9/10/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 9/10/2025 hydrocortisone Tablet, uncoated 4 mg Anticipated Available Manufacturing 9/10/2025 ezetimibe~simvastatin Tablet 10 mg~40 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 9/10/2025 fingolimod hydrochloride Capsule 560 microgram Anticipated Available Manufacturing 9/10/2025 estradiol Drug delivery system, transdermal .39 mg Current Unavailable Manufacturing 9/10/2025 estradiol Drug delivery system, transdermal .78 mg Current Unavailable Manufacturing 9/10/2025 estradiol Drug delivery system, transdermal 1.17 mg Current Unavailable Manufacturing 9/10/2025 estradiol Drug delivery system, transdermal 1.56 mg Current Unavailable Manufacturing 9/10/2025 lenalidomide Capsule 5 mg Current Limited Availability Manufacturing 9/10/2025 bleomycin sulfate Injection, powder for 15000 IU Anticipated Available Manufacturing 9/10/2025 doxorubicin hydrochloride Injection, concentrated 20 mg Resolved Available Manufacturing 9/10/2025 methylphenidate hydrochloride Tablet, modified release 18 mg Current Limited Availability Manufacturing 9/10/2025 methylphenidate hydrochloride Tablet, modified release 36 mg Current Limited Availability Manufacturing 9/10/2025 tranexamic acid Tablet, film coated 500 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 8/10/2025 galantamine hydrobromide Capsule, modified release 30.768 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 8/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 8/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 8/10/2025 valsartan~hydrochlorothiazide Tablet, film coated 320 mg~25 mg Resolved Available Manufacturing 8/10/2025 temozolomide Capsule, hard 20 mg Anticipated Available Manufacturing 8/10/2025 escitalopram oxalate Tablet, film coated 25.548 mg Anticipated Available Manufacturing 8/10/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Unavailable Manufacturing 8/10/2025 anastrozole Tablet, film coated 1 mg Current Limited Availability Manufacturing 8/10/2025 clonidine hydrochloride Tablet 100 microgram Resolved Available Manufacturing 8/10/2025 hydrochlorothiazide~irbesartan Tablet, film coated 12.5 mg~150 mg Current Unavailable Manufacturing 8/10/2025 hydrochlorothiazide~irbesartan Tablet, film coated 25 mg~300 mg Current Unavailable Manufacturing 8/10/2025 metformin hydrochloride Tablet, film coated 1000 mg Current Unavailable Unexpected increase in consumer demand 8/10/2025 Mecasermin Injection, solution 10 mg/mL Resolved Available Unexpected increase in consumer demand 8/10/2025 erlotinib hydrochloride Tablet, film coated 27.32 mg Current Unavailable Unexpected increase in consumer demand 8/10/2025 spironolactone Tablet, uncoated 25 mg Resolved Available Manufacturing 8/10/2025 bortezomib Injection, solution 3.5 mg Resolved Available Manufacturing 8/10/2025 paracetamol Tablet, modified release 665 mg Resolved Available Transport / Logistic issues / Storage capacity issues 8/10/2025 naproxen Tablet, uncoated 250 mg Resolved Available Manufacturing 8/10/2025 tranexamic acid Tablet, film coated 500 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 8/10/2025 trandolapril Capsule, hard 2 mg Resolved Available Manufacturing 8/10/2025 rifampicin Capsule, hard 300 mg Current Unavailable Manufacturing 8/10/2025 clindamycin phosphate Cream 22.8 mg/g Resolved Available Transport / Logistic issues / Storage capacity issues 8/10/2025 paclitaxel Injection, concentrated 6 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 8/10/2025 labetalol hydrochloride Tablet, film coated 100 mg Current Limited Availability Manufacturing 8/10/2025 dosulepin hydrochloride Tablet, film coated 75 mg Current Limited Availability Manufacturing 8/10/2025 metformin hydrochloride Tablet, film coated 1000 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 8/10/2025 acetylcysteine Injection, concentrated 2 g Current Limited Availability Manufacturing 7/10/2025 topiramate Tablet, film coated 25 mg Current Unavailable Manufacturing 7/10/2025 ciprofloxacin hydrochloride Tablet, film coated 277.5 mg Current Unavailable Manufacturing 7/10/2025 acetazolamide sodium Injection, powder for 549.5 mg Current Unavailable Manufacturing 7/10/2025 lamotrigine Tablet, chewable 50 mg Anticipated Available Manufacturing 7/10/2025 lamotrigine Tablet, chewable 100 mg Current Unavailable Manufacturing 7/10/2025 olanzapine Tablet, film coated 5 mg Current Unavailable Manufacturing 7/10/2025 methylphenidate hydrochloride Capsule, modified release 10 mg Current Limited Availability Manufacturing 7/10/2025 levetiracetam Tablet, film coated 500 mg Current Limited Availability Manufacturing 7/10/2025 sildenafil citrate Tablet, film coated 140.45 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 7/10/2025 sulfamethoxazole~trimethoprim Tablet, uncoated 800 mg~160 mg Resolved Available Manufacturing 7/10/2025 exemestane Tablet, sugar coated 25 mg Anticipated Available Manufacturing 7/10/2025 olanzapine Tablet, orally disintegrating 10 mg Anticipated Available Manufacturing 7/10/2025 olanzapine Tablet, orally disintegrating 5 mg Anticipated Available Manufacturing 7/10/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Current Unavailable Manufacturing 7/10/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Anticipated Available Manufacturing 7/10/2025 galantamine hydrobromide Capsule, modified release 10.252 mg Current Unavailable Manufacturing 7/10/2025 galantamine hydrobromide Capsule, modified release 30.756 mg Current Unavailable Manufacturing 7/10/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 7/10/2025 indapamide hemihydrate Tablet, sugar coated 2.5 mg Current Limited Availability Manufacturing 7/10/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 7/10/2025 isotretinoin Capsule, soft 10 mg Current Unavailable Manufacturing 7/10/2025 isotretinoin Capsule, soft 20 mg Current Unavailable Manufacturing 7/10/2025 enalapril maleate Tablet 5 mg Anticipated Available Manufacturing 7/10/2025 phenobarbital Tablet, uncoated 30 mg Anticipated Available Manufacturing 7/10/2025 metformin hydrochloride Tablet, film coated 1000 mg Current Unavailable Manufacturing 7/10/2025 citalopram hydrobromide Tablet, film coated 49.98 mg Resolved Available Manufacturing 7/10/2025 ezetimibe Tablet, uncoated 10 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 7/10/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Manufacturing 7/10/2025 ivabradine hydrochloride Tablet, film coated 8.085 mg Resolved Available Manufacturing 7/10/2025 teriflunomide Tablet, film coated 14 mg Current Unavailable Manufacturing 7/10/2025 pregabalin Capsule, hard 300 mg Anticipated Available Manufacturing 7/10/2025 oseltamivir phosphate Capsule, hard 98.524 mg Current Limited Availability Manufacturing 7/10/2025 sitagliptin hydrochloride monohydrate~metformin hydrochloride Tablet, modified release 56.685 mg~1000 mg Anticipated Available Manufacturing 7/10/2025 Teriparatide Injection, solution .25 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 7/10/2025 Teriparatide Injection, solution 250 microgram/mL Current Unavailable Manufacturing 7/10/2025 minocycline hydrochloride dihydrate Tablet, film coated 54 mg Resolved Available Manufacturing 7/10/2025 olanzapine Injection, powder for 10 mg Resolved Available Unexpected increase in consumer demand 7/10/2025 ciprofloxacin hydrochloride Tablet, film coated 873.32 mg Current Limited Availability Manufacturing 7/10/2025 methylphenidate hydrochloride Capsule, modified release 30 mg Current Limited Availability Manufacturing 7/10/2025 amoxicillin trihydrate Oral Liquid, powder for 28.7 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 6/10/2025 - 2025.10.05
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated trandolapril~verapamil hydrochloride Tablet, film coated 4 mg~240 mg Current Limited Availability Manufacturing 3/10/2025 acetylcholine chloride Solution, powder for irrigation 10 mg/mL Resolved Available Manufacturing 3/10/2025 ramipril Tablet, uncoated 1.25 mg Anticipated Available Manufacturing 3/10/2025 Equine antithymocyte immunoglobulin Injection, solution 50 mg/mL Resolved Available Manufacturing 3/10/2025 bromocriptine mesilate Tablet, uncoated 2.87 mg Resolved Available Manufacturing 3/10/2025 buprenorphine hydrochloride Injection, solution 324 microgram/mL Current Unavailable Manufacturing 3/10/2025 iopromide Injection, solution 498.72 mg/mL Current Unavailable Manufacturing 3/10/2025 silver sulfadiazine Cream 10 mg/g Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 3/10/2025 silver sulfadiazine Cream 10 mg/g Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 3/10/2025 risperidone Tablet, film coated 2 mg Anticipated Available Manufacturing 3/10/2025 pioglitazone hydrochloride Tablet 49.9 mg Anticipated Available Manufacturing 3/10/2025 hydrocortisone sodium succinate Injection, powder for 134 mg Anticipated Available Manufacturing 3/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 3/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Manufacturing 3/10/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 3/10/2025 trandolapril Capsule, hard .5 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 trandolapril Capsule, hard 1 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 trandolapril Capsule, hard 2 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 trandolapril Capsule, hard 4 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 metoprolol succinate Tablet, modified release 95 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 metoprolol succinate Tablet, modified release 47.5 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 metoprolol succinate Tablet, modified release 190 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 metoprolol succinate Tablet, modified release 23.75 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 paclitaxel Injection, concentrated 300 mg Current Unavailable Manufacturing 3/10/2025 adrenaline (epinephrine) acid tartrate~articaine hydrochloride Injection, solution 18.2 microgram/mL~40 mg/mL Resolved Available Transport / Logistic issues / Storage capacity issues 3/10/2025 citalopram hydrobromide Tablet, film coated 12.495 mg Current Limited Availability Manufacturing 3/10/2025 bimatoprost Eye Drops .3 mg/mL Current Unavailable Manufacturing 3/10/2025 methylphenidate hydrochloride Capsule, modified release 60 mg Current Unavailable Manufacturing 3/10/2025 hydrochlorothiazide~irbesartan Tablet, film coated 12.5 mg~300 mg Current Unavailable Manufacturing 3/10/2025 nizatidine Capsule, hard 150 mg Current Unavailable Manufacturing 3/10/2025 ambrisentan Tablet, film coated 10 mg Anticipated Available Manufacturing 3/10/2025 mefenamic acid Capsule, hard 250 mg Current Unavailable Manufacturing 3/10/2025 dabigatran etexilate mesilate Capsule, hard 126.83 mg Current Limited Availability Manufacturing 3/10/2025 posaconazole Tablet, modified release 100 mg Resolved Available Manufacturing 3/10/2025 sacubitril~valsartan Tablet, film coated 48.6 mg~51.4 mg Resolved Available Manufacturing 3/10/2025 valsartan~sacubitril Tablet, film coated 102.8 mg~97.2 mg Resolved Available Manufacturing 3/10/2025 carboplatin Injection, solution 10 mg/mL Resolved Available Unexpected increase in demand due to other sponsors unable to supply 3/10/2025 iotroxate meglumine Injection, solution 105.46 mg/mL Current Unavailable Transport / Logistic issues / Storage capacity issues 3/10/2025 methylphenidate hydrochloride Capsule, modified release 20 mg Current Limited Availability Manufacturing 3/10/2025 methylphenidate hydrochloride Capsule, modified release 40 mg Current Unavailable Manufacturing 3/10/2025 Measles virus~Rubella virus~Mumps virus Injection, powder for 1000 CCID50~1000 CCID50~5000 CCID50 Resolved Available Unexpected increase in consumer demand 3/10/2025 prazosin hydrochloride Tablet, uncoated 1.095 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 2/10/2025 prazosin hydrochloride Tablet, uncoated 5.476 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 2/10/2025 metformin hydrochloride Tablet, film coated 500 mg Current Unavailable Manufacturing 2/10/2025 valsartan~hydrochlorothiazide Tablet, film coated 320 mg~25 mg Current Limited Availability Manufacturing 2/10/2025 risperidone Tablet, film coated .5 mg Current Unavailable Manufacturing 2/10/2025 entecavir Tablet, film coated .5 mg Current Unavailable Manufacturing 2/10/2025 entecavir Tablet, film coated 1 mg Anticipated Available Manufacturing 2/10/2025 Trastuzumab Injection, solution 600 mg Resolved Available Manufacturing 2/10/2025 rosuvastatin calcium Tablet, film coated 20.84 mg Current Limited Availability Unexpected increase in consumer demand 2/10/2025 azacitidine Injection, powder for 100 mg Resolved Available Manufacturing 2/10/2025 tranexamic acid Tablet, film coated 500 mg Current Unavailable Manufacturing 2/10/2025 ambrisentan Tablet, film coated 5 mg Anticipated Available Manufacturing 2/10/2025 deferasirox Tablet, film coated 90 mg Current Limited Availability Manufacturing 2/10/2025 deferasirox Tablet, film coated 360 mg Current Limited Availability Manufacturing 2/10/2025 metoprolol succinate Tablet, modified release 23.75 mg Current Limited Availability Manufacturing 2/10/2025 sitagliptin hydrochloride monohydrate~metformin hydrochloride Tablet, film coated 56.69 mg~1000 mg Resolved Available Manufacturing 2/10/2025 quinagolide hydrochloride Tablet, uncoated .0819 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 2/10/2025 prazosin hydrochloride Tablet, uncoated 1.1 mg Current Unavailable Manufacturing 2/10/2025 sertraline hydrochloride Tablet, film coated 56 mg Current Unavailable Manufacturing 2/10/2025 sertraline hydrochloride Tablet, film coated 112 mg Current Limited Availability Manufacturing 2/10/2025 mirtazapine Tablet, film coated 30 mg Resolved Available Manufacturing 2/10/2025 live varicella vaccine Injection, powder for 2700 PFU/mL Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 1/10/2025 sertraline hydrochloride Tablet, film coated 55.96 mg Current Unavailable Manufacturing 1/10/2025 risperidone Tablet 1 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 1/10/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Current Limited Availability Manufacturing 1/10/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Current Limited Availability Manufacturing 1/10/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Current Unavailable Manufacturing 1/10/2025 ceftaroline fosamil Injection, powder for 600 mg Resolved Available Manufacturing 1/10/2025 clopidogrel hydrogen sulfate~aspirin Tablet 97.87 mg~100 mg Resolved Available Manufacturing 1/10/2025 live varicella vaccine Injection, powder for 4000 PFU/mL Current Only available under NIP or government programs Unexpected increase in consumer demand 1/10/2025 mesalazine Tablet, enteric coated 800 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 1/10/2025 Rabies virus Injection, powder for 2.5 IU Current Emergency Supply Only Unexpected increase in consumer demand 1/10/2025 teriflunomide Tablet, film coated 14 mg Current Limited Availability Manufacturing 1/10/2025 Mecasermin Injection, solution 10 mg/mL Current Limited Availability Unexpected increase in consumer demand 1/10/2025 estradiol~estradiol~norethisterone acetate Drug delivery system, transdermal .78 mg~.62 mg~2.7 mg Resolved Available Manufacturing 1/10/2025 GluureaLys(ahx)hbedCC Injection, powder for 25 microgram Current Unavailable Manufacturing 1/10/2025 tranexamic acid Tablet, film coated 500 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 1/10/2025 rifampicin Capsule, hard 150 mg Current Limited Availability Manufacturing 1/10/2025 lidocaine hydrochloride monohydrate Injection, solution 20 mg/mL Resolved Available Manufacturing 1/10/2025 prazosin hydrochloride Tablet, uncoated 2.2 mg Current Unavailable Manufacturing 1/10/2025 prazosin hydrochloride Tablet, uncoated 5.5 mg Current Unavailable Manufacturing 1/10/2025 primidone Tablet, uncoated 250 mg Current Limited Availability Manufacturing 30/09/2025 lidocaine hydrochloride Gel 20 mg/g Current Limited Availability Manufacturing 30/09/2025 pantoprazole sodium sesquihydrate Tablet, enteric coated 45.4 mg Current Limited Availability Unexpected increase in consumer demand 30/09/2025 midazolam Injection, solution 50 mg Resolved Available Manufacturing 30/09/2025 midazolam Injection, solution 50 mg Current Limited Availability Manufacturing 30/09/2025 docetaxel Injection, concentrated 80 mg Resolved Available Manufacturing 30/09/2025 rosuvastatin calcium Tablet, film coated 41.68 mg Current Limited Availability Manufacturing 30/09/2025 rosuvastatin calcium Tablet, film coated 10.42 mg Current Unavailable Manufacturing 30/09/2025 pregabalin Capsule, hard 75 mg Current Limited Availability Manufacturing 30/09/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Current Unavailable Manufacturing 30/09/2025 dabigatran etexilate mesilate Capsule, hard 172.95 mg Current Unavailable Manufacturing 30/09/2025 oseltamivir phosphate Capsule, hard 98.524 mg Current Limited Availability Manufacturing 30/09/2025 cabazitaxel Injection, concentrated 60 mg Current Limited Availability Manufacturing 30/09/2025 fentanyl citrate Injection, solution 785 microgram Current Unavailable Manufacturing 30/09/2025 ropivacaine hydrochloride Injection, solution 10 mg/mL Current Unavailable Manufacturing 30/09/2025 gefitinib Tablet, film coated 250 mg Discontinued Unavailable Commercial Changes / Commercial viability 30/09/2025 betamethasone valerate Cream 1.21 mg/g Resolved Available Manufacturing 29/09/2025 fludarabine phosphate Injection, powder for 50 mg Current Limited Availability Manufacturing 29/09/2025 finasteride Tablet, film coated 1 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 29/09/2025 sulfamethoxazole~trimethoprim Tablet, uncoated 800 mg~160 mg Current Limited Availability Manufacturing 29/09/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in consumer demand 29/09/2025 chloramphenicol Eye Drops 5 mg/mL Current Unavailable Manufacturing 29/09/2025 phenobarbital Tablet, uncoated 30 mg Anticipated Available Manufacturing 29/09/2025 quetiapine fumarate Tablet, modified release 57.5 mg Anticipated Available Unexpected increase in consumer demand 29/09/2025 irbesartan Tablet, film coated 75 mg Current Limited Availability Manufacturing 29/09/2025 ivabradine hydrochloride Tablet, film coated 5.39 mg Resolved Available Manufacturing 29/09/2025 dimethyl fumarate Capsule, enteric 120 mg Resolved Available Manufacturing 29/09/2025 lurasidone hydrochloride Tablet, film coated 40 mg Current Unavailable Manufacturing 29/09/2025 lurasidone hydrochloride Tablet, film coated 80 mg Current Unavailable Manufacturing 29/09/2025 potassium chloride Tablet, modified release 600 mg Current Limited Availability Manufacturing 29/09/2025 spironolactone Tablet, uncoated 25 mg Current Limited Availability Manufacturing 29/09/2025 tetrabenazine Tablet, uncoated 25 mg Current Unavailable Manufacturing 29/09/2025 lidocaine hydrochloride Injection, solution 10 mg/mL Current Unavailable Manufacturing 29/09/2025 cisatracurium besilate Injection, solution 2.68 mg/mL Current Unavailable Manufacturing 29/09/2025 olanzapine Tablet, film coated 5 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 29/09/2025 olanzapine Wafer 5 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 29/09/2025
ドイツ
- 2025.10.13
Active ingredients Message type Date of last message Type of reason AM designation Tinzaparin sodium Change notification 10.10.2025 Production problem innohep 4,500 Anti-Xa I.E. Solution for injection Carbamazepine Initial report 09.10.2025 Production problem Carbamazepine Aristo 600 mg prolonged-release tablets Carbamazepine Initial report 09.10.2025 Production problem Carbamazepine Aristo 300 mg prolonged-release tablets Ezetimibe; simvastatin Change notification 09.10.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/80 mg tablets Ezetimibe; simvastatin Change notification 09.10.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/40 mg tablets Ezetimibe; simvastatin Change notification 09.10.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/20 mg tablets Ezetimibe; simvastatin Change notification 09.10.2025 Production problem EZETIMIBE/SIMVA BASICS 10 mg/10 mg tablets Esomeprazole hemimagnesium Change notification 09.10.2025 Production problem ESOMEPRAZOLE BASICS 40 mg gastro-resistant hard capsules Esomeprazole hemimagnesium Change notification 09.10.2025 Production problem ESOMEPRAZOLE BASICS 20 mg gastro-resistant hard capsules Moxifloxacin hydrochloride (Ph.Eur.) ((with information on water content (1:x))) Initial report 09.10.2025 Other Moxifloxacin Holsten 400 mg film-coated tablets Leflunomide Initial report 09.10.2025 Other Leflunomide Bluefish 20 mg film-coated tablets Methylphenidate hydrochloride Change notification 09.10.2025 Other METHYLPHENIDATE 20 mg tablets Methylphenidate hydrochloride Change notification 09.10.2025 Other METHYLPHENIDATE 5 mg tablets Leflunomide Initial report 09.10.2025 Other Leflunomide Bluefish 10 mg film-coated tablets Potassium canrenoate Change notification 09.10.2025 Production problem Aldactone 10 ml Canrenoate Urapidil Initial report 09.10.2025 Production problem Urapidil Bluefish 90 mg hard capsules, delayed release Urapidil Initial report 09.10.2025 Production problem Urapidil Bluefish 30 mg hard capsules, delayed release Methylphenidate hydrochloride Change notification 09.10.2025 Other Methylphenidate-ratiopharm 40 mg hard capsules with modified release Primidone Change notification 09.10.2025 Production problem Mylepsinum Quetiapine fumarate (Ph.Eur.) Change notification 09.10.2025 Other Quetiapine AbZ 150 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 09.10.2025 Other Quetiapine-ratiopharm 300 mg prolonged-release tablets Risperidone Change notification 09.10.2025 Production problem Risperidone-ratiopharm 25 mg powder and solvent for the preparation of a depot injection suspension Risperidone Change notification 09.10.2025 Production problem Risperidone-ratiopharm 37.5 mg powder and solvent for the preparation of a depot injection suspension Risperidone Change notification 09.10.2025 Production problem Risperidone-ratiopharm 50 mg powder and solvent for the preparation of a depot injection suspension Pramipexole dihydrochloride monohydrate Change notification 09.10.2025 Other Pramipexole-ratiopharm 0.52 mg prolonged-release tablets Pramipexole dihydrochloride monohydrate Change notification 09.10.2025 Other Pramipexole-ratiopharm 0.26 mg prolonged-release tablets Carbamazepine Change notification 09.10.2025 Other Carbamazepine-ratiopharm 400 mg prolonged-release tablets Carbamazepine Change notification 09.10.2025 Other Carbamazepine-ratiopharm 200 mg prolonged-release tablets Ribavirin Change notification 09.10.2025 Other Ribavirin-ratiopharm 400 mg film-coated tablets Ribavirin Change notification 09.10.2025 Other Ribavirin-ratiopharm 200 mg film-coated tablets Salbutamol sulfate Initial report 09.10.2025 Other Sultanol metered-dose inhaler Aprepitant Change notification 09.10.2025 Production problem Aprepitant STADA 125 mg hard capsules Human insulin (with manufacturing details); isophane insulin suspension for injection (Ph.Eur.) Change notification 08.10.2025 Other Actraphane 30 FlexPen 100 IU/ml injection suspension in injector – OP(10x3ml) Isophane insulin suspension for injection (Ph.Eur.) Change notification 08.10.2025 Other Protaphane FlexPen 100 IU/ml injection suspension in injector – OP(10x3ml) Nitrendipine Change notification 08.10.2025 Other Nitrendipine AL 20 Aprepitant Change notification 08.10.2025 Other Aprepitant AL 125 mg hard capsules Oxazepam Change notification 08.10.2025 Other Oxazepam AL 10 Quetiapine fumarate (Ph.Eur.) Change notification 08.10.2025 Other Quetiapine AL 50 mg prolonged-release tablets Amoxicillin trihydrate Change notification 08.10.2025 Other Amoxicillin AL TS Doxepin hydrochloride (Ph.Eur.) Change notification 07.10.2025 Production problem Doxepin 25 Holsten Azithromycin dihydrate Change notification 07.10.2025 Other Azithromycin AL 250 mg film-coated tablets Lacosamide Initial report 07.10.2025 Production problem Lacosamide UCB 10 mg/ml syrup Aprepitant Change notification 07.10.2025 Production problem Aprepitant beta 80 mg hard capsules Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Production problem Quetiapine beta 50 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Production problem Quetiapine beta 300 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Production problem Quetiapine beta 200 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Production problem Quetiapine beta 150 mg prolonged-release tablets Atomoxetine hydrochloride Change notification 07.10.2025 Production problem Atomoxetine beta 80 mg hard capsules Aprepitant Change notification 07.10.2025 Production problem Aprepitant beta 125 mg and 80 mg hard capsules Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Other Seroquel Prolong 200 mg prolonged-release tablets Amlodipine besylate; Perindopril tert-butylamine Change notification 07.10.2025 Other Perindopril/amlodipine Denk 4 mg/5 mg tablets Amlodipine besylate; Perindopril tert-butylamine Change notification 07.10.2025 Other Perindopril/amlodipine Denk 4 mg/10 mg tablets Amlodipine besylate; Perindopril tert-butylamine Change notification 07.10.2025 Other Perindopril/Amlodipine Denk 8 mg/10 mg tablets Clopidogrel besylate Change notification 07.10.2025 Other Clopidogrel Denk 75 mg film-coated tablets Methylphenidate hydrochloride Change notification 07.10.2025 Other Methylphenidate AL 36 mg prolonged-release tablets Methylphenidate hydrochloride Change notification 07.10.2025 Other Methylphenidate AL 27 mg prolonged-release tablets Epirubicin hydrochloride Change notification 07.10.2025 Production problem Epirubicin Hikma 2 mg/ml concentrate for solution for infusion Trimipramine mesylate Change notification 06.10.2025 Other Trimipramine – 1 A Pharma 40 mg/ml oral drops, solution Tenofovir disoproxil Initial report 06.10.2025 Other Tenofovir disoproxil Viatris 245 mg film-coated tablets – OP30 Tenofovir disoproxil Change notification 06.10.2025 Other Tenofovir disoproxil Mylan 245 mg film-coated tablets – OP90(3×30) Imiquimod Change notification 06.10.2025 Production problem Aldara 5% cream – OP24 Dacarbazine citrate Change notification 06.10.2025 Other Dacarbazine Lipomed 500 mg powder for solution for infusion Prednisolone acetate Change notification 06.10.2025 Production problem Prednifluid 10 mg/ml eye drop suspension Sevelamer Change notification 06.10.2025 Other Renagel 800 mg film-coated tablets – OP(1×180) Methylphenidate hydrochloride Change notification 06.10.2025 Other Methylphenidate hydrochloride-neuraxpharm 27 mg prolonged-release tablets Phenylephrine hydrochloride Change notification 06.10.2025 Production problem Neosynephrine-POS 10% Gentamicin sulfate Change notification 06.10.2025 Production problem Gentamicin-POS Beclometasone dipropionate (Ph.Eur.) Change notification 06.10.2025 Other Beclorhinol aquosum 50 micrograms - 2025.10.05
Active ingredients Message type Date of last message Type of reason AM designation Enalapril maleate; hydrochlorothiazide Change notification 03.10.2025 Production problem Renacor Methyldopa (Ph.Eur.) Initial report 03.10.2025 Production problem Presinol 500 Cefaclor monohydrate Change notification 02.10.2025 Other Cefaclor 125 TS – 1 A Pharma Cefpodoxime proxetil Initial report 02.10.2025 Other Cefpodoxime – 1 A Pharma 40 mg/5 ml powder for oral suspension Morphine hemisulfate 2.5 hydrate Initial report 02.10.2025 Production problem Substitol 30 mg hard capsules, delayed release Oxycodone hydrochloride (Ph.Eur.) Change notification 02.10.2025 Production problem Oxygesic 5 mg Rifampicin Change notification 02.10.2025 Other EREMFAT 150 mg Oxycodone hydrochloride Change notification 02.10.2025 Other OXYGESIC 10 mg Pyrazinamide Initial report 02.10.2025 Production problem Pyrafat 500 mg Azithromycin dihydrate Change notification 02.10.2025 Other Azithromycin AL 250 mg film-coated tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 200 mg prolonged-release tablets Calcium acetate hydrate (with information on water content (1:x)) Initial report 01.10.2025 Production problem Calcium acetate-Nefro 950mg Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 150 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 50 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 400 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 300 mg prolonged-release tablets Vinorelbine tartrate Initial report 01.10.2025 Production problem Bendarelbin 10 mg/ml concentrate for solution for infusion Sodium perchlorate 1 H<2>O Change notification 30.09.2025 Other Irenat drops Galantamine hydrobromide Change notification 30.09.2025 Production problem Galantamine Heumann 8 mg hard capsules, delayed release Galantamine hydrobromide Change notification 30.09.2025 Production problem Galantamine Heumann 16 mg hard capsules, delayed release Galantamine hydrobromide Change notification 30.09.2025 Production problem Galantamine Heumann 24 mg hard capsules, delayed release Clomethiazole hemidisilate Change notification 30.09.2025 Other Distraneurin mixture Pramipexole dihydrochloride monohydrate Change notification 30.09.2025 Other Pramipexole HEXAL 0.26 mg prolonged-release tablets Pramipexole dihydrochloride monohydrate Change notification 30.09.2025 Other Pramipexole HEXAL 0.52 mg prolonged-release tablets Phenoxymethylpenicillin potassium Change notification 30.09.2025 Other Pen Mega – 1 A Pharma Rifampicin sodium Initial report 30.09.2025 Other Eremfat i.v. 600mg Ascorbic acid; biotin; cholecalciferol; cyanocobalamin; dexpanthenol; folic acid hydrate ((with information on water content (1:x))); Nicotinamide; pyridoxine hydrochloride; retinol palmitate; riboflavin phosphate sodium; thiamine hydrochloride; all-rac-phytomenadione; all-rac-alpha-tocopherol Initial report 30.09.2025 Production problem Viant powder for solution for infusion Tropicamide Change notification 30.09.2025 Production problem Mydriaticum Stulln UD Ipratropium bromide (Ph.Eur.); salbutamol sulfate Change notification 30.09.2025 Production problem COMBIPRASAL 0.5 mg / 2.5 mg solution for nebulizer Ipratropium bromide Change notification 30.09.2025 Production problem Ipratropium bromide 250 micrograms / 1 ml Stulln Paliperidone palmitate Change notification 30.09.2025 Other Paliperidone AL 25 mg depot injection suspension in a pre-filled syringe Methylphenidate hydrochloride Change notification 30.09.2025 Other Methylphenidate AL 36 mg prolonged-release tablets Paliperidone palmitate Change notification 30.09.2025 Other Paliperidone AL 50 mg Depot injection suspension in a pre-filled syringe Beclomethasone dipropionate (Ph.Eur.) Change notification 29.09.2025 Other Beclorhinol aquosum 50 micrograms Insulin glargine Change notification 29.09.2025 Other Semglee 100 units/ml injection solution in pre-filled pen – OP(5x3ml) Insulin glargine Change notification 29.09.2025 Other Semglee Methylphenidate hydrochloride Initial report 29.09.2025 Other Equasym Retard 40 mg hard capsules with modified release
フランス
- 2025.10.13
Active ingredients Statut Update Specialty betamethasone (dipropionate), betamethasone (sodium phosphate) Supply tension 09/10/2025 Diprostene, suspension for injection in pre-filled syringe pancreas powder Supply tension 08/10/2025 Eurobiol 40 000 U, gastroresistant capsule liothyronine sodium Supply tension 07/10/2025 Cynomel 0.025 mg, scored tablet furosemide Marketing discontinuation 06/10/2025 Lasilix Retard 60 mg, capsule peginterferon alfa-2a Return to availability 06/10/2025 Pegasys 90 micrograms, 135 micrograms and 180 micrograms solution for injection in prefilled syringes - 2025.10.05
Active ingredients Statut Update Specialty tranexamic acid Return to availability 03/10/2025 Exacyl 500 mg, film-coated tablet chlorpromazine (hydrochloride) Out of stock 03/10/2025 Largactil 100 mg, scored film-coated tablet praziquantel Out of stock 02/10/2025 Biltricide 600 mg, film-coated quadrisectible tablet fluorouracil Out of stock 02/10/2025 Fluorouracil Pfizer 50 mg/ml, dilutable solution for infusion20 ml and 100 ml bottle atropine (sulfate) Supply tension 02/10/2025 Atropine 0.3%, eye drops Immunoglobulin normal human (IgG) Supply tension 01/10/2025 Immunoglobulin normal human IV and SC (based on) propofol Out of stock 29/09/2025 Diprivan 10 mg/mL, emulsion for injection in pre-filled syringe propofol Supply tension 29/09/2025 Diprivan 20 mg/mL, emulsion for injection in pre-filled syringe
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EU
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