更新された供給不足状況を示しています。
ある時点での供給不足の全体的状況は「供給関連情報」に定期的にアップします。
米国
- 2025.09.28
- 2025.09.28
New
September 26, 2025
- Irinotecan Hydrochloride Injection (Discontinuation)
Updated
September 23, 2025
- Amino Acid Injection (Currently in Shortage)
- Clindamycin Phosphate Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Heparin Sodium Injection (Currently in Shortage)
- Nitroglycerin Injection (Currently in Shortage)
- Sterile Water Irrigant (Currently in Shortage)
September 22, 2025
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Lisdexamfetamine Dimesylate Tablet, Chewable (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Metronidazole Injection (Currently in Shortage)
- Naltrexone Hydrochloride Tablet (Currently in Shortage)
- Technetium TC-99M Pyrophosphate Kit Injection (Currently in Shortage)
- 2025.09.22
- 2025.09.22
New
September 19, 2025
- Obeticholic Acid Tablet (Discontinuation)
- Pilocarpine Hydrochloride Tablet (Discontinuation)
September 18, 2025
- Desonide Lotion (Discontinuation)
- Fluphenazine Hydrochloride Tablet (Discontinuation)
Updated
September 18, 2025
- Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Currently in Shortage)
- Epinephrine Bitartrate, Lidocaine Hydrochloride Injection (Currently in Shortage)
September 17, 2025
- Carboplatin Injection (Currently in Shortage)
- Hydroxypropyl Cellulose (1600000 Wamw) Insert (Currently in Shortage)
- Streptozocin Powder, For Solution (Currently in Shortage)
September 16, 2025
- Amino Acid Injection (Currently in Shortage)
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Azacitidine Injection (Currently in Shortage)
- Sodium Acetate Injection (Currently in Shortage)
September 15, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Azacitidine Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Lisdexamfetamine Dimesylate Tablet, Chewable (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Naltrexone Hydrochloride Tablet (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- 2025.09.15
- 2025.09.15
New
September 11, 2025
- Gemcitabine Hydrochloride Injection (Discontinuation)
- Homatropine Methylbromide and Hydrocodone Bitartrate Syrup (Discontinuation)
- Oxycodone Hydrochloride Oral Solution (Discontinuation)
September 09, 2025
- Azithromycin Injection (Discontinuation)
- Vancomycin Hydrochloride Injection (Discontinuation)
September 08, 2025
- Sumatriptan Nasal Spray (Discontinuation)
- Vecuronium Bromide Injection (Discontinuation)
この期間中のUpdated情報はありません。
- 2025.09.08
Generic Name Shortage Status Revision Date Created Date Acetylcysteine Oral and Inhalation Solution Resolved Shortages 5-Sep-25 8-Jun-15 Adenosine Injection Current Shortages 5-Sep-25 3-Apr-23 Amphetamine Mixed Salts, Immediate-Release Tablets Current Shortages 5-Sep-25 27-Jul-22 Clindamycin Phosphate Injection Current Shortages 5-Sep-25 25-Jun-15 Dimenhydrinate Injection Current Shortages 5-Sep-25 14-Aug-25 Furosemide Injection Current Shortages 5-Sep-25 18-May-17 Liraglutide Injection Current Shortages 5-Sep-25 20-Jul-23 Methylphenidate Immediate-Release Tablets Current Shortages 5-Sep-25 31-Jul-23 Nitroglycerin Injection Current Shortages 5-Sep-25 24-Aug-23 Prednisone Oral Tablets Current Shortages 5-Sep-25 15-May-19 BCG Live Intravesical Current Shortages 4-Sep-25 15-Jan-19 Cefdinir Oral Presentations Current Shortages 4-Sep-25 29-Jun-23 Eptifibatide Injection Current Shortages 4-Sep-25 20-May-20 Hydroxyethyl Starch (Hetastarch) Current Shortages 4-Sep-25 9-Apr-25 Imatinib Mesylate Tablets Current Shortages 4-Sep-25 14-May-25 Insulin Glargine Injection (Recombinant) Current Shortages 4-Sep-25 19-Feb-25 Lidocaine Injection Current Shortages 4-Sep-25 23-Jun-15 Meperidine Hydrochloride Injection Current Shortages 4-Sep-25 20-Mar-24 Mercaptopurine Tablets Current Shortages 4-Sep-25 8-Jan-24 Nalbuphine Injection Current Shortages 4-Sep-25 8-Nov-22 Neomycin and Polymyxin B Sulfates Genitourinary Irrigant Current Shortages 4-Sep-25 26-Jun-23 Octreotide Intramuscular Injection Kits Current Shortages 4-Sep-25 4-Jun-25 Penicillin V Potassium Oral Presentations Current Shortages 4-Sep-25 17-May-23 Sucralfate Tablets Current Shortages 4-Sep-25 28-Oct-22 Varenicline tablets (Chantix) Current Shortages 4-Sep-25 24-Jun-21 50% Dextrose Injection Current Shortages 3-Sep-25 12-Dec-21 Acamprosate Calcium Tablets Current Shortages 3-Sep-25 30-Sep-24 Acetaminophen Injection Current Shortages 3-Sep-25 12-Mar-25 Bivalirudin Injection Current Shortages 3-Sep-25 12-Nov-24 Conjugated Estrogens Injection Current Shortages 3-Sep-25 21-May-25 Decitabine Injection Current Shortages 3-Sep-25 2-Aug-23 Dexamethasone Oral Solution/Elixir Current Shortages 3-Sep-25 16-Apr-25 Diltiazem Hydrochloride Injection Current Shortages 3-Sep-25 29-Jan-25 Dorzolamide Ophthalmic Solution Current Shortages 3-Sep-25 19-Jun-24 Leucovorin Calcium Injection Current Shortages 3-Sep-25 2-Jun-15 Magnesium Sulfate Injection Current Shortages 3-Sep-25 29-May-15 Metyrosine Capsules Current Shortages 3-Sep-25 3-Sep-25 Midazolam Injection Current Shortages 3-Sep-25 14-Jun-19 Mitomycin Injection Current Shortages 3-Sep-25 3-Mar-23 Mometasone Furoate Aerosol for Oral Inhalation Current Shortages 3-Sep-25 29-Jul-25 Morphine Oral Solution Current Shortages 3-Sep-25 19-Feb-25 Pantoprazole Injection Current Shortages 3-Sep-25 28-Mar-19 Phenytoin Sodium Injection Current Shortages 3-Sep-25 20-Dec-22 Propranolol Hydrochloride Injection Current Shortages 3-Sep-25 10-Apr-23 Propranolol Hydrochloride Oral Solution Current Shortages 3-Sep-25 25-Feb-25 Remifentanil Injection Current Shortages 3-Sep-25 22-Jun-22 Rocuronium Injection Current Shortages 3-Sep-25 9-Feb-17 Vasopressin Injection Current Shortages 3-Sep-25 27-Feb-24 Vecuronium Bromide Injection Current Shortages 3-Sep-25 8-Sep-15 - 2025.09.08
New
September 4, 2025
- Azelastine Hydrochloride; Fluticasone Propionate Nasal Spray (Discontinuation)
Updated
September 3, 2025
- Amino Acid Injection (Currently In Shortage)
- Dexmedetomidine Hydrochloride Injection (Currently In Shortage)
- Nitroglycerin Injection (Currently In Shortage)
- Ropivacaine Hydrochloride Injection (Currently In Shortage)
September 2, 2025
- Hydromorphone Hydrochloride Injection (Currently In Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently In Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently In Shortage)
- Morphine Sulfate Injection (Currently In Shortage)
- Naltrexone Hydrochloride Tablet (Currently In Shortage)
- Sodium Bicarbonate Injection (Currently In Shortage)
- 2025.09.01
- 2025.09.01
New
August 29, 2025
- Methotrexate Injection (Discontinuation)
August 27, 2025
- Dobutamine Hydrochloride Injection (Discontinuation)
- Dopamine Hydrochloride Injection (Discontinuation)
August 25, 2025
- Bumetanide Injection (Currently In Shortage)
Updated
August 29, 2025
- Lidocaine Hydrochloride Solution (Resolved)
August 28, 2025
- Somatropin Injection (Resolved)
August 26, 2025
- Indocyanine Green Injection (Resolved)
August 25, 2025
- Penicillin G Benzathine Injection (Currently In Shortage)
カナダ
カナダの情報はありません。
オーストラリア
- 2025.09.28
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated fentanyl Drug delivery system, transdermal 4.2 mg Discontinued Unavailable Manufacturing 26/09/2025 fentanyl Drug delivery system, transdermal 8.4 mg Discontinued Unavailable Manufacturing 26/09/2025 fentanyl Drug delivery system, transdermal 12.6 mg Discontinued Unavailable Manufacturing 26/09/2025 fentanyl Drug delivery system, transdermal 16.8 mg Discontinued Unavailable Manufacturing 26/09/2025 fentanyl Drug delivery system, transdermal 2.1 mg Discontinued Unavailable Manufacturing 26/09/2025 stannous chloride~etifenin Injection, powder for .42 mg~20 mg Current Unavailable Manufacturing 26/09/2025 nortriptyline Tablet, film coated 10 mg Resolved Available Manufacturing 26/09/2025 ceftazidime pentahydrate Injection, powder for 2.328 g Current Limited Availability Manufacturing 26/09/2025 finasteride Tablet, film coated 1 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 26/09/2025 olanzapine Tablet, orally disintegrating 5 mg Anticipated Available Manufacturing 26/09/2025 fentanyl Drug delivery system, transdermal 5.1 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 26/09/2025 fentanyl Drug delivery system, transdermal 2.55 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 26/09/2025 vecuronium bromide Injection, powder for 10 mg Current Limited Availability Manufacturing 26/09/2025 pioglitazone hydrochloride Tablet 49.9 mg Anticipated Available Manufacturing 26/09/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 26/09/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Manufacturing 26/09/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 26/09/2025 ondansetron hydrochloride dihydrate Tablet, film coated 4.986 mg Anticipated Available Manufacturing 26/09/2025 galantamine hydrobromide Capsule, modified release 10.252 mg Current Unavailable Manufacturing 26/09/2025 galantamine hydrobromide Capsule, modified release 30.756 mg Current Unavailable Manufacturing 26/09/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 26/09/2025 sildenafil citrate Tablet, film coated 28.1 mg Current Unavailable Manufacturing 26/09/2025 quetiapine fumarate Tablet, modified release 57.565 mg Anticipated Available Manufacturing 26/09/2025 pramipexole dihydrochloride monohydrate Tablet, modified release .375 mg Current Limited Availability Manufacturing 26/09/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Unexpected increase in consumer demand 26/09/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 26/09/2025 citalopram hydrobromide Tablet, film coated 12.495 mg Current Unavailable Manufacturing 26/09/2025 citalopram hydrobromide Tablet, film coated 49.98 mg Current Unavailable Manufacturing 26/09/2025 fluticasone propionate Inhalation, powder for 20 mg/g Resolved Available Manufacturing 26/09/2025 cidofovir Injection, concentrated 75 mg/mL Resolved Available Manufacturing 26/09/2025 ambrisentan Tablet, film coated 5 mg Anticipated Available Manufacturing 26/09/2025 lorazepam Tablet 1 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 26/09/2025 ezetimibe~rosuvastatin calcium Tablet~Tablet, film coated 10 mg~41.6 mg Resolved Available Manufacturing 26/09/2025 stannous chloride dihydrate Injection, powder for 19.2 microgram/mL Current Unavailable Manufacturing 26/09/2025 nizatidine Capsule, hard 300 mg Anticipated Available Manufacturing 26/09/2025 mesalazine Suppository, compressed 1000 mg Resolved Available Transport / Logistic issues / Storage capacity issues 26/09/2025 lidocaine hydrochloride~adrenaline (epinephrine) acid tartrate Injection, solution 20 mg/mL~9.1 microgram/mL Current Limited Availability Manufacturing 25/09/2025 sildenafil citrate Tablet, uncoated 35.1 mg Anticipated Available Manufacturing 25/09/2025 valaciclovir hydrochloride Tablet, film coated 556.275 mg Anticipated Available Manufacturing 25/09/2025 risperidone Tablet, film coated 2 mg Anticipated Available Manufacturing 25/09/2025 bisoprolol fumarate Tablet 2.5 mg Current Limited Availability Manufacturing 25/09/2025 bisoprolol fumarate Tablet 5 mg Anticipated Available Manufacturing 25/09/2025 bisoprolol fumarate Tablet 10 mg Anticipated Available Manufacturing 25/09/2025 sildenafil citrate Tablet, film coated 140.45 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 25/09/2025 ondansetron hydrochloride dihydrate Tablet, film coated 9.972 mg Current Limited Availability Manufacturing 25/09/2025 exemestane Tablet, sugar coated 25 mg Anticipated Available Manufacturing 25/09/2025 montelukast sodium Tablet, chewable 5.2 mg Resolved Available Unexpected increase in consumer demand 25/09/2025 linezolid Tablet, film coated 600 mg Current Unavailable Manufacturing 25/09/2025 carbidopa monohydrate~entacapone~levodopa Tablet, film coated 27 mg~200 mg~100 mg Current Limited Availability Unexpected increase in consumer demand 25/09/2025 carbidopa monohydrate~entacapone~levodopa Tablet, film coated 40.5 mg~200 mg~150 mg Current Limited Availability Unexpected increase in consumer demand 25/09/2025 levodopa~carbidopa monohydrate~entacapone Tablet, film coated 200 mg~54.1 mg~200 mg Current Limited Availability Unexpected increase in consumer demand 25/09/2025 irbesartan Tablet, film coated 150 mg Current Unavailable Manufacturing 25/09/2025 nizatidine Capsule, hard 150 mg Current Unavailable Manufacturing 25/09/2025 nitisinone Tablet 10 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 25/09/2025 nitisinone Tablet 5 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 25/09/2025 lamotrigine Tablet, chewable 50 mg Anticipated Available Manufacturing 25/09/2025 lamotrigine Tablet, chewable 100 mg Current Limited Availability Manufacturing 25/09/2025 naltrexone hydrochloride Tablet, film coated 50 mg Resolved Available Manufacturing 25/09/2025 desvenlafaxine Tablet, modified release 100 mg Resolved Available Manufacturing 25/09/2025 valaciclovir hydrochloride Tablet, film coated 1112 mg Anticipated Available Manufacturing 25/09/2025 methyl aminolevulinate hydrochloride Cream 200 mg/g Resolved Available Manufacturing 25/09/2025 terbinafine hydrochloride Tablet, uncoated 281.25 mg Current Limited Availability Manufacturing 24/09/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.9 mg Current Limited Availability Unexpected increase in consumer demand 24/09/2025 indapamide hemihydrate~perindopril erbumine Tablet 1.25 mg~4 mg Current Unavailable Manufacturing 24/09/2025 tobramycin Capsule, hard 28 mg Anticipated Available Manufacturing 24/09/2025 valsartan~hydrochlorothiazide Tablet, film coated 320 mg~25 mg Current Unavailable Manufacturing 24/09/2025 ezetimibe~rosuvastatin calcium Tablet~Tablet, film coated 10 mg~41.583 mg Resolved Available Manufacturing 24/09/2025 entecavir Tablet, film coated 1 mg Anticipated Available Manufacturing 24/09/2025 anastrozole Tablet, film coated 1 mg Current Limited Availability Manufacturing 24/09/2025 carbidopa monohydrate~levodopa Tablet, uncoated 27 mg~100 mg Current Limited Availability Manufacturing 24/09/2025 cabazitaxel Injection, concentrated 60 mg Current Limited Availability Manufacturing 24/09/2025 oxaliplatin Injection, concentrated 100 mg Resolved Available Manufacturing 24/09/2025 sugammadex sodium Injection, solution 217.6 mg Current Unavailable Manufacturing 24/09/2025 trandolapril Capsule, hard 2 mg Current Unavailable Manufacturing 24/09/2025 Tiger snake antivenom Injection, concentrated 3000 U Resolved Available Manufacturing 24/09/2025 fluvastatin sodium Tablet, modified release 84.24 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 24/09/2025 prazosin hydrochloride Tablet, uncoated 2.19 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 23/09/2025 bromocriptine mesilate Tablet, uncoated 2.87 mg Current Unavailable Manufacturing 23/09/2025 Somatropin Injection, powder for 12 mg/mL Anticipated Available Unexpected increase in consumer demand 23/09/2025 fluticasone propionate~salmeterol xinafoate Inhalation, pressurised 125 microgram/actuation~36.3 microgram/actuation Resolved Available Unexpected increase in consumer demand 23/09/2025 capecitabine Tablet, film coated 500 mg Resolved Available Unexpected increase in consumer demand 23/09/2025 Rabies virus Injection, powder for 2.5 IU Current Limited Availability Unexpected increase in consumer demand 23/09/2025 letrozole Tablet, film coated 2.5 mg Current Limited Availability Manufacturing 23/09/2025 posaconazole Tablet, modified release 100 mg Current Unavailable Manufacturing 23/09/2025 Adalimumab Injection, solution 20 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 23/09/2025 Adalimumab Injection, solution 40 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 23/09/2025 metronidazole Tablet, film coated 400 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 23/09/2025 carbidopa monohydrate~levodopa Tablet, uncoated 26.9 mg~100 mg Current Limited Availability Manufacturing 23/09/2025 spironolactone Tablet, film coated 100 mg Current Limited Availability Manufacturing 23/09/2025 bupivacaine hydrochloride monohydrate Injection, solution 52.7 mg Resolved Available Manufacturing 22/09/2025 sertraline hydrochloride Tablet, film coated 56 mg Discontinued Unavailable Commercial Changes / Commercial viability 22/09/2025 sertraline hydrochloride Tablet, film coated 112 mg Discontinued Unavailable Commercial Changes / Commercial viability 22/09/2025 varenicline tartrate~varenicline tartrate Tablet, film coated 1.71 mg~.85 mg Discontinued Unavailable Manufacturing 22/09/2025 varenicline tartrate Tablet, film coated 1.71 mg Discontinued Unavailable Manufacturing 22/09/2025 fludarabine phosphate Injection, powder for 50 mg Current Limited Availability Manufacturing 22/09/2025 aripiprazole Tablet, uncoated 30 mg Resolved Available Manufacturing 22/09/2025 methylphenidate hydrochloride Capsule, modified release 10 mg Current Limited Availability Manufacturing 22/09/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.9 mg Resolved Available Unexpected increase in consumer demand 22/09/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Anticipated Available Manufacturing 22/09/2025 ropivacaine hydrochloride Injection, solution 2 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 22/09/2025 ropivacaine hydrochloride Injection, solution 7.5 mg/mL Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 22/09/2025 ropivacaine hydrochloride Injection, solution 100 mg Resolved Available Transport / Logistic issues / Storage capacity issues 22/09/2025 quetiapine fumarate Tablet, modified release 345.39 mg Current Limited Availability Manufacturing 22/09/2025 quetiapine fumarate Tablet, modified release 345.39 mg Anticipated Available Manufacturing 22/09/2025 quetiapine fumarate Tablet, modified release 230.26 mg Anticipated Available Manufacturing 22/09/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Unexpected increase in consumer demand 22/09/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Manufacturing 22/09/2025 metformin hydrochloride Tablet, film coated 1000 mg Current Unavailable Unexpected increase in consumer demand 22/09/2025 solifenacin succinate Tablet, film coated 5 mg Current Unavailable Manufacturing 22/09/2025 Mecasermin Injection, solution 10 mg/mL Anticipated Available Unexpected increase in consumer demand 22/09/2025 naloxone hydrochloride dihydrate Injection 440 microgram Resolved Available Unexpected increase in consumer demand 22/09/2025 midazolam maleate Solution 10.2 mg Resolved Available Manufacturing 22/09/2025 nitrofurantoin Capsule, hard 100 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 22/09/2025 palonosetron hydrochloride~fosnetupitant chloride hydrochloride Injection, concentrated 280 microgram~260 mg Anticipated Available Manufacturing 22/09/2025 thiotepa Injection, powder for 15 mg Current Unavailable Commercial Changes / Commercial viability 22/09/2025 thiotepa Injection, powder for 100 mg Current Unavailable Commercial Changes / Commercial viability 22/09/2025 thiotepa Injection, powder for 400 mg Current Unavailable Commercial Changes / Commercial viability 22/09/2025 nitrofurantoin Capsule, hard 100 mg Current Limited Availability Manufacturing 22/09/2025 clindamycin phosphate Cream 22.8 mg/g Current Limited Availability Transport / Logistic issues / Storage capacity issues 22/09/2025 midazolam Injection, solution 1 mg/mL Current Unavailable Manufacturing 22/09/2025 methylphenidate hydrochloride Capsule, modified release 20 mg Current Limited Availability Manufacturing 22/09/2025 galantamine hydrobromide~galantamine Capsule, modified release 20.51 mg~16 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 22/09/2025 - 2025.09.22
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated aripiprazole Tablet, uncoated 30 mg Resolved Available Manufacturing 22/09/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.9 mg Current Unavailable Unexpected increase in consumer demand 22/09/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.9 mg Resolved Available Unexpected increase in consumer demand 22/09/2025 quetiapine fumarate Tablet, modified release 345.39 mg Current Limited Availability Manufacturing 22/09/2025 quetiapine fumarate Tablet, modified release 345.39 mg Anticipated Available Manufacturing 22/09/2025 quetiapine fumarate Tablet, modified release 230.26 mg Anticipated Available Manufacturing 22/09/2025 metformin hydrochloride Tablet, film coated 1000 mg Current Unavailable Unexpected increase in consumer demand 22/09/2025 solifenacin succinate Tablet, film coated 5 mg Current Unavailable Manufacturing 22/09/2025 naloxone hydrochloride dihydrate Injection 440 microgram Resolved Available Unexpected increase in consumer demand 22/09/2025 nitrofurantoin Capsule, hard 100 mg Current Limited Availability Manufacturing 22/09/2025 methylphenidate hydrochloride Capsule, modified release 20 mg Current Limited Availability Manufacturing 22/09/2025 sertraline hydrochloride Tablet, film coated 55.96 mg Anticipated Available Manufacturing 19/09/2025 risperidone Tablet 1 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 19/09/2025 ceftazidime pentahydrate Injection, powder for 2.328 g Anticipated Available Manufacturing 19/09/2025 bisoprolol fumarate Tablet 2.5 mg Current Limited Availability Manufacturing 19/09/2025 bisoprolol fumarate Tablet 5 mg Anticipated Available Manufacturing 19/09/2025 bisoprolol fumarate Tablet 10 mg Anticipated Available Manufacturing 19/09/2025 pioglitazone hydrochloride Tablet, uncoated 16.53 mg Resolved Available Manufacturing 19/09/2025 lamivudine Tablet, film coated 300 mg Anticipated Available Manufacturing 19/09/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 19/09/2025 temozolomide Capsule, hard 5 mg Anticipated Available Manufacturing 19/09/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Anticipated Available Manufacturing 19/09/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Anticipated Available Manufacturing 19/09/2025 montelukast sodium Tablet, film coated 10.4 mg Resolved Available Manufacturing 19/09/2025 pramipexole dihydrochloride monohydrate Tablet, modified release .75 mg Current Limited Availability Manufacturing 19/09/2025 pramipexole dihydrochloride monohydrate Tablet, modified release .375 mg Anticipated Available Manufacturing 19/09/2025 pramipexole dihydrochloride monohydrate Tablet, modified release 1.5 mg Current Limited Availability Manufacturing 19/09/2025 tranexamic acid Tablet, film coated 500 mg Current Unavailable Manufacturing 19/09/2025 ambrisentan Tablet, film coated 5 mg Anticipated Available Manufacturing 19/09/2025 montelukast sodium Tablet, chewable 5.2 mg Current Unavailable Manufacturing 19/09/2025 spironolactone Tablet, uncoated 25 mg Current Limited Availability Manufacturing 19/09/2025 naltrexone hydrochloride Tablet, film coated 50 mg Anticipated Available Manufacturing 19/09/2025 furosemide Injection, solution 20 mg Anticipated Available Manufacturing 19/09/2025 aripiprazole monohydrate Injection, powder for 416.07 mg Current Unavailable Manufacturing 19/09/2025 lamotrigine Tablet, chewable 100 mg Current Unavailable Manufacturing 18/09/2025 lamotrigine Tablet, chewable 200 mg Current Unavailable Manufacturing 18/09/2025 sildenafil citrate Tablet, film coated 140.45 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 18/09/2025 ondansetron hydrochloride dihydrate Tablet, film coated 9.972 mg Current Limited Availability Manufacturing 18/09/2025 metronidazole Tablet, uncoated 400 mg Current Limited Availability Manufacturing 18/09/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Current Unavailable Manufacturing 18/09/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Anticipated Available Manufacturing 18/09/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 18/09/2025 indapamide hemihydrate Tablet, sugar coated 2.5 mg Anticipated Available Manufacturing 18/09/2025 montelukast sodium Tablet, chewable 5.2 mg Resolved Available Manufacturing 18/09/2025 montelukast sodium Tablet, chewable 5.2 mg Current Unavailable Unexpected increase in consumer demand 18/09/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 18/09/2025 ciprofloxacin hydrochloride Tablet, film coated 277.5 mg Resolved Available Manufacturing 18/09/2025 ciprofloxacin hydrochloride Tablet, film coated 555 mg Resolved Available Manufacturing 18/09/2025 ciprofloxacin hydrochloride Tablet, film coated 832.5 mg Resolved Available Manufacturing 18/09/2025 ropivacaine hydrochloride Injection, solution 40 mg Resolved Available Transport / Logistic issues / Storage capacity issues 18/09/2025 ropivacaine hydrochloride Injection, solution 150 mg Resolved Available Transport / Logistic issues / Storage capacity issues 18/09/2025 risperidone Tablet, film coated .5 mg Current Unavailable Manufacturing 18/09/2025 amlodipine besilate~atorvastatin calcium trihydrate Tablet, film coated 6.94 mg~43.376 mg Current Unavailable Manufacturing 18/09/2025 amlodipine besilate~atorvastatin calcium trihydrate Tablet, film coated 13.88 mg~10.844 mg Current Unavailable Manufacturing 18/09/2025 amlodipine besilate~atorvastatin calcium trihydrate Tablet, film coated 13.88 mg~43.376 mg Current Limited Availability Manufacturing 18/09/2025 citalopram hydrobromide Tablet, film coated 12.495 mg Current Unavailable Manufacturing 18/09/2025 citalopram hydrobromide Tablet, film coated 49.98 mg Current Unavailable Manufacturing 18/09/2025 nizatidine Capsule, hard 150 mg Current Unavailable Manufacturing 18/09/2025 ivabradine hydrochloride Tablet, film coated 8.085 mg Current Unavailable Manufacturing 18/09/2025 bimatoprost Eye Drops .3 mg/mL Anticipated Available Manufacturing 18/09/2025 eplerenone Tablet, film coated 25 mg Anticipated Available Manufacturing 18/09/2025 lacosamide Tablet, film coated 50 mg Anticipated Available Manufacturing 18/09/2025 risperidone Oral Liquid, solution 1 mg/mL Current Unavailable Manufacturing 18/09/2025 montelukast sodium Tablet, chewable 5.2 mg Resolved Available Manufacturing 18/09/2025 lamotrigine Tablet, chewable 50 mg Anticipated Available Manufacturing 18/09/2025 lamotrigine Tablet, chewable 100 mg Anticipated Available Manufacturing 18/09/2025 lamotrigine Tablet, chewable 200 mg Current Unavailable Manufacturing 18/09/2025 rivaroxaban Tablet, film coated 10 mg Anticipated Available Manufacturing 18/09/2025 rivaroxaban Tablet, film coated 10 mg Anticipated Available Manufacturing 18/09/2025 dosulepin hydrochloride Tablet, film coated 75 mg Anticipated Available Manufacturing 18/09/2025 minocycline hydrochloride dihydrate Tablet, film coated 54 mg Current Limited Availability Manufacturing 18/09/2025 ciprofloxacin hydrochloride Tablet, film coated 873.32 mg Anticipated Available Manufacturing 18/09/2025 betamethasone valerate Cream 1.21 mg/g Current Limited Availability Manufacturing 17/09/2025 bromocriptine mesilate Tablet, uncoated 2.87 mg Current Unavailable Manufacturing 17/09/2025 fentanyl Drug delivery system, transdermal 16.8 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 17/09/2025 mycophenolate mofetil Tablet, film coated 500 mg Current Limited Availability Manufacturing 17/09/2025 entacapone~carbidopa monohydrate~levodopa Tablet, film coated 200 mg~13.5 mg~50 mg Current Limited Availability Manufacturing 17/09/2025 midazolam Injection, solution 50 mg Anticipated Available Manufacturing 17/09/2025 hydromorphone hydrochloride Injection, solution 2 mg/mL Discontinued Unavailable Commercial Changes / Commercial viability 17/09/2025 rifampicin Capsule, hard 150 mg Current Limited Availability Manufacturing 17/09/2025 rifampicin Capsule, hard 300 mg Current Unavailable Manufacturing 17/09/2025 methylphenidate hydrochloride Capsule, modified release 40 mg Current Limited Availability Manufacturing 17/09/2025 Epoetin beta Injection 16666.67 IU/mL Discontinued Reduction in supply until supply is exhausted Transport / Logistic issues / Storage capacity issues 16/09/2025 lidocaine hydrochloride Injection, solution 20 mg/mL Current Unavailable Manufacturing 16/09/2025 tetrabenazine Tablet, uncoated 25 mg Current Unavailable Manufacturing 16/09/2025 montelukast sodium Tablet, chewable 5.2 mg Current Unavailable Manufacturing 16/09/2025 phenoxymethylpenicillin potassium Tablet, film coated 560 mg Current Limited Availability Manufacturing 16/09/2025 fluticasone propionate Inhalation, powder for 20 mg/g Current Limited Availability Manufacturing 16/09/2025 cidofovir Injection, concentrated 75 mg/mL Current Limited Availability Manufacturing 16/09/2025 levodopa~carbidopa monohydrate Tablet, uncoated 100 mg~27 mg Current Limited Availability Manufacturing 16/09/2025 aciclovir Eye Ointment .135 g Resolved Available Manufacturing 16/09/2025 ropivacaine hydrochloride Injection, solution 7.5 mg/mL Current Limited Availability Manufacturing 16/09/2025 ropivacaine hydrochloride Injection, solution 7.5 mg/mL Current Unavailable Manufacturing 16/09/2025 norethisterone~ethinylestradiol Tablet, uncoated 500 microgram~36 microgram Anticipated Available Manufacturing 16/09/2025 mesalazine Suppository, compressed 1000 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 16/09/2025 primidone Tablet, uncoated 250 mg Anticipated Available Manufacturing 15/09/2025 lidocaine hydrochloride~adrenaline (epinephrine) acid tartrate Injection, solution 20 mg/mL~9.1 microgram/mL Current Unavailable Manufacturing 15/09/2025 benzathine benzylpenicillin tetrahydrate Injection, suspension 1200000 USP Unit Current Limited Availability Manufacturing 15/09/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Resolved Available Manufacturing 15/09/2025 valsartan~hydrochlorothiazide Tablet, film coated 160 mg~12.5 mg Resolved Available Manufacturing 15/09/2025 ropivacaine hydrochloride Injection, solution 200 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 15/09/2025 quetiapine fumarate Tablet, modified release 57.565 mg Resolved Available Unexpected increase in consumer demand 15/09/2025 salmeterol xinafoate~fluticasone propionate Inhalation, pressurised 36.3 microgram/actuation~125 microgram/actuation Current Limited Availability Unexpected increase in consumer demand 15/09/2025 entecavir Tablet, film coated 1 mg Anticipated Available Manufacturing 15/09/2025 tadalafil Tablet, film coated 5 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 15/09/2025 hydrocortisone Tablet, uncoated 4 mg Resolved Available Manufacturing 15/09/2025 benzathine benzylpenicillin tetrahydrate Injection, suspension 600000 USP Unit Current Unavailable Manufacturing 15/09/2025 metronidazole Injection, solution 500 mg Resolved Available Transport / Logistic issues / Storage capacity issues 15/09/2025 methylphenidate hydrochloride Tablet, modified release 18 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 15/09/2025 lorazepam Tablet 1 mg Resolved Available Manufacturing 15/09/2025 carboplatin Injection, solution 10 mg/mL Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 15/09/2025 framycetin sulfate Eye and Ear Drops 5 mg/mL Resolved Available Transport / Logistic issues / Storage capacity issues 15/09/2025 nizatidine Capsule 150 mg Resolved Available Manufacturing 15/09/2025 - 2025.09.15
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated codeine phosphate hemihydrate Oral Liquid, solution 5 mg/mL Current Unavailable Manufacturing 12/09/2025 ciprofloxacin hydrochloride Tablet, film coated 277.5 mg Current Unavailable Manufacturing 12/09/2025 nortriptyline Tablet, film coated 10 mg Anticipated Available Manufacturing 12/09/2025 bethanechol chloride Tablet, uncoated 10 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 12/09/2025 levetiracetam Tablet, film coated 1000 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 12/09/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 12/09/2025 sildenafil citrate Tablet, film coated 28.1 mg Current Unavailable Manufacturing 12/09/2025 quetiapine fumarate Tablet, modified release 230.26 mg Anticipated Available Manufacturing 12/09/2025 adefovir dipivoxil Tablet 10 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 12/09/2025 donepezil hydrochloride Tablet, film coated 5 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 12/09/2025 acarbose Tablet 100 mg Current Limited Availability Manufacturing 12/09/2025 levetiracetam Solution 100 mg/mL Current Limited Availability Manufacturing 12/09/2025 ezetimibe Tablet, uncoated 10 mg Current Unavailable Unexpected increase in consumer demand 12/09/2025 ezetimibe Tablet, uncoated 10 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 12/09/2025 irbesartan Tablet, film coated 150 mg Current Unavailable Manufacturing 12/09/2025 hydrochlorothiazide~irbesartan Tablet, film coated 12.5 mg~300 mg Current Unavailable Manufacturing 12/09/2025 ivabradine hydrochloride Tablet, film coated 8.085 mg Current Unavailable Manufacturing 12/09/2025 mebeverine hydrochloride Tablet, film coated 135 mg Current Unavailable Manufacturing 12/09/2025 latanoprost Eye Drops, solution .05 mg/mL Anticipated Available Manufacturing 12/09/2025 eplerenone Tablet, film coated 25 mg Anticipated Available Manufacturing 12/09/2025 midazolam maleate Solution 10.2 mg Current Limited Availability Manufacturing 12/09/2025 ramipril Tablet, uncoated 1.25 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 12/09/2025 indocyanine green Injection, powder for 25 mg Resolved Available Manufacturing 12/09/2025 phenytoin sodium Injection, solution 250 mg Anticipated Available Manufacturing 12/09/2025 levodopa~carbidopa monohydrate Tablet, uncoated 100 mg~26.9 mg Current Limited Availability Manufacturing 12/09/2025 dosulepin hydrochloride Tablet, film coated 75 mg Anticipated Available Manufacturing 12/09/2025 valaciclovir hydrochloride Tablet, film coated 1112 mg Anticipated Available Manufacturing 12/09/2025 trandolapril Capsule 4 mg Current Limited Availability Manufacturing 12/09/2025 naproxen Tablet, modified release 750 mg Resolved Available Manufacturing 11/09/2025 propranolol hydrochloride Tablet, film coated 10 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 11/09/2025 propranolol hydrochloride Tablet, film coated 40 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 11/09/2025 risperidone Tablet, film coated 1 mg Current Unavailable Manufacturing 11/09/2025 olsalazine sodium Capsule 250 mg Current Unavailable Manufacturing 11/09/2025 octreotide Injection, solution 500 microgram Current Limited Availability Manufacturing 11/09/2025 tramadol hydrochloride Tablet, modified release 200 mg Resolved Available Manufacturing 11/09/2025 olanzapine Tablet, orally disintegrating 20 mg Current Limited Availability Manufacturing 11/09/2025 phenoxymethylpenicillin potassium Oral Liquid, powder for 28.284 mg/mL Current Limited Availability Manufacturing 11/09/2025 fluorouracil Injection, solution 5000 mg Current Unavailable Unexpected increase in consumer demand 11/09/2025 riluzole Tablet, film coated 50 mg Resolved Available Manufacturing 11/09/2025 allopurinol Tablet 300 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 11/09/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 11/09/2025 acamprosate calcium Tablet, enteric coated 333 mg Resolved Available Manufacturing 11/09/2025 fenofibrate Tablet, film coated 145 mg Resolved Available Manufacturing 11/09/2025 lacosamide Tablet, film coated 100 mg Current Limited Availability Manufacturing 11/09/2025 metoprolol succinate Tablet, modified release 47.5 mg Resolved Available Manufacturing 11/09/2025 Teriparatide Injection, solution .25 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 11/09/2025 rivaroxaban Tablet, film coated 10 mg Anticipated Available Manufacturing 11/09/2025 Teriparatide Injection, solution 250 microgram/mL Current Unavailable Manufacturing 11/09/2025 metformin hydrochloride~sitagliptin hydrochloride monohydrate Tablet, film coated 1000 mg~56.69 mg Current Unavailable Manufacturing 11/09/2025 olsalazine sodium Tablet, uncoated 500 mg Current Unavailable Manufacturing 11/09/2025 estradiol hemihydrate Drug delivery system, transdermal 3.09 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 11/09/2025 venlafaxine Capsule, modified release 75 mg Current Unavailable Manufacturing 10/09/2025 venlafaxine Capsule, modified release 150 mg Current Unavailable Manufacturing 10/09/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 10/09/2025 methylphenidate hydrochloride Capsule, modified release 10 mg Current Limited Availability Manufacturing 10/09/2025 ciprofloxacin hydrochloride Tablet, film coated 277.5 mg Current Unavailable Manufacturing 10/09/2025 ciprofloxacin hydrochloride Tablet, film coated 832.5 mg Current Unavailable Manufacturing 10/09/2025 ropivacaine hydrochloride Injection, solution 200 mg Anticipated Available Transport / Logistic issues / Storage capacity issues 10/09/2025 capecitabine Tablet, film coated 500 mg Discontinued Unavailable Manufacturing 10/09/2025 ezetimibe~simvastatin Tablet 10 mg~10 mg Current Unavailable Manufacturing 10/09/2025 simvastatin~ezetimibe Tablet 20 mg~10 mg Current Unavailable Manufacturing 10/09/2025 methylphenidate hydrochloride Capsule, modified release 60 mg Current Unavailable Manufacturing 10/09/2025 naproxen Tablet, modified release 1000 mg Resolved Available Manufacturing 10/09/2025 naproxen Tablet, modified release 750 mg Resolved Available Manufacturing 10/09/2025 atenolol Tablet, film coated 50 mg Current Unavailable Manufacturing 10/09/2025 azacitidine Injection, powder for 100 mg Discontinued Unavailable Commercial Changes / Commercial viability 10/09/2025 rifampicin Capsule, hard 150 mg Current Limited Availability Manufacturing 10/09/2025 rifampicin Capsule, hard 300 mg Current Unavailable Manufacturing 10/09/2025 methylphenidate hydrochloride Capsule, modified release 20 mg Current Limited Availability Manufacturing 10/09/2025 methylphenidate hydrochloride Capsule, modified release 30 mg Current Unavailable Manufacturing 10/09/2025 methylphenidate hydrochloride Capsule, modified release 40 mg Current Unavailable Manufacturing 10/09/2025 tramadol hydrochloride Capsule 50 mg Current Limited Availability Manufacturing 9/09/2025 acetylcysteine Injection, concentrated 2 g Anticipated Available Manufacturing 9/09/2025 octreotide Injection, solution 100 microgram Current Limited Availability Manufacturing 9/09/2025 octreotide Injection, solution 50 microgram Current Limited Availability Manufacturing 9/09/2025 leflunomide Tablet, film coated 20 mg Anticipated Available Manufacturing 9/09/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 9/09/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 9/09/2025 ceftaroline fosamil Injection, powder for 600 mg Current Limited Availability Manufacturing 9/09/2025 amlodipine besilate~atorvastatin calcium trihydrate Tablet, film coated 6.94 mg~43.376 mg Current Unavailable Manufacturing 9/09/2025 atorvastatin calcium trihydrate~amlodipine besilate Tablet, film coated 10.844 mg~13.88 mg Current Unavailable Manufacturing 9/09/2025 atorvastatin calcium trihydrate~amlodipine besilate Tablet, film coated 43.376 mg~13.88 mg Current Limited Availability Manufacturing 9/09/2025 midazolam Injection, solution 50 mg Anticipated Available Manufacturing 9/09/2025 clonidine hydrochloride Tablet 100 microgram Current Limited Availability Unexpected increase in consumer demand 9/09/2025 amiodarone hydrochloride Tablet, uncoated 100 mg Current Unavailable Manufacturing 9/09/2025 spironolactone Tablet, uncoated 25 mg Current Unavailable Manufacturing 9/09/2025 spironolactone Tablet, uncoated 100 mg Current Limited Availability Manufacturing 9/09/2025 proguanil hydrochloride~atovaquone Tablet, film coated 100 mg~250 mg Resolved Available Manufacturing 9/09/2025 labetalol hydrochloride Tablet, film coated 100 mg Current Limited Availability Manufacturing 9/09/2025 citalopram hydrobromide Tablet, film coated 49.96 mg Resolved Available Manufacturing 9/09/2025 nizatidine Capsule 150 mg Current Limited Availability Manufacturing 9/09/2025 galantamine hydrobromide Capsule, modified release 20.512 mg Resolved Available Manufacturing 8/09/2025 propranolol hydrochloride Tablet, film coated 40 mg Resolved Available Manufacturing 8/09/2025 ropivacaine hydrochloride Injection, solution 100 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 8/09/2025 carboplatin Injection, solution 450 mg Resolved Available Manufacturing 8/09/2025 Trastuzumab Injection, solution 600 mg Anticipated Available Manufacturing 8/09/2025 lacosamide Tablet, film coated 150 mg Current Limited Availability Manufacturing 8/09/2025 sildenafil citrate Tablet, film coated 70.24 mg Current Limited Availability Commercial Changes / Commercial viability 8/09/2025 desmopressin acetate Spray, solution .1 mg/mL Current Unavailable Product recall 8/09/2025 spironolactone Tablet, film coated 100 mg Anticipated Available Manufacturing 8/09/2025 methyl aminolevulinate hydrochloride Cream 200 mg/g Current Limited Availability Manufacturing 8/09/2025 - 2025.09.08
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated Epoetin beta Injection 6666.66 IU/mL Discontinued Reduction in supply until supply is exhausted Transport / Logistic issues / Storage capacity issues 5/09/2025 Epoetin beta Injection 10000 IU/mL Discontinued Reduction in supply until supply is exhausted Transport / Logistic issues / Storage capacity issues 5/09/2025 Epoetin beta Injection 13333.33 IU/mL Discontinued Reduction in supply until supply is exhausted Transport / Logistic issues / Storage capacity issues 5/09/2025 Epoetin beta Injection 16666.67 IU/mL Discontinued Reduction in supply until supply is exhausted Transport / Logistic issues / Storage capacity issues 5/09/2025 Epoetin beta Injection 20000 IU/mL Discontinued Reduction in supply until supply is exhausted Transport / Logistic issues / Storage capacity issues 5/09/2025 Epoetin beta Injection 16666.67 IU/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 5/09/2025 prazosin hydrochloride Tablet, uncoated 2.19 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 5/09/2025 bromocriptine mesilate Tablet, uncoated 2.87 mg Current Unavailable Manufacturing 5/09/2025 topiramate Tablet, film coated 25 mg Current Limited Availability Manufacturing 5/09/2025 ciprofloxacin hydrochloride Tablet, film coated 277.5 mg Current Unavailable Manufacturing 5/09/2025 tetrabenazine Tablet, uncoated 25 mg Anticipated Available Manufacturing 5/09/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 5/09/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Manufacturing 5/09/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Anticipated Available Manufacturing 5/09/2025 galantamine hydrobromide Capsule, modified release 30.756 mg Current Unavailable Manufacturing 5/09/2025 galantamine hydrobromide Capsule, modified release 30.756 mg Current Unavailable Manufacturing 5/09/2025 montelukast sodium Tablet, chewable 5.2 mg Current Limited Availability Manufacturing 5/09/2025 montelukast sodium Tablet, chewable 5.2 mg Current Unavailable Unexpected increase in consumer demand 5/09/2025 ceftaroline fosamil Injection, powder for 600 mg Current Limited Availability Manufacturing 5/09/2025 ropivacaine hydrochloride Injection, solution 100 mg Anticipated Available Transport / Logistic issues / Storage capacity issues 5/09/2025 raloxifene hydrochloride Tablet, film coated 60 mg Current Unavailable Manufacturing 5/09/2025 quetiapine fumarate Tablet, modified release 345.39 mg Anticipated Available Manufacturing 5/09/2025 quetiapine fumarate Tablet, modified release 460.52 mg Current Limited Availability Manufacturing 5/09/2025 quetiapine fumarate Tablet, modified release 345.39 mg Anticipated Available Manufacturing 5/09/2025 Trastuzumab Injection, solution 600 mg Anticipated Available Manufacturing 5/09/2025 linezolid Tablet, film coated 600 mg Current Unavailable Manufacturing 5/09/2025 fenofibrate Tablet, film coated 145 mg Anticipated Available Manufacturing 5/09/2025 oseltamivir phosphate Capsule, hard 98.524 mg Current Limited Availability Manufacturing 5/09/2025 carboplatin Injection, solution 450 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 5/09/2025 permethrin Cream 50 mg/g Resolved Available Commercial Changes / Commercial viability 5/09/2025 abacavir sulfate~lamivudine Tablet, film coated 702 mg~300 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 5/09/2025 calcitonin salmon Injection, solution 100 IU/mL Resolved Available Commercial Changes / Commercial viability 4/09/2025 pentetic acid Injection, powder for 5 mg Current Unavailable Manufacturing 4/09/2025 medronic acid Injection, powder for 10 mg Current Unavailable Manufacturing 4/09/2025 lamotrigine Tablet, chewable 50 mg Anticipated Available Manufacturing 4/09/2025 nystatin Oral Liquid 100000 IU/mL Current Unavailable Commercial Changes / Commercial viability 4/09/2025 pioglitazone hydrochloride Tablet 16.63 mg Resolved Available Manufacturing 4/09/2025 fampridine Tablet, modified release 10 mg Resolved Available Transport / Logistic issues / Storage capacity issues 4/09/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Current Limited Availability Manufacturing 4/09/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Resolved Available Manufacturing 4/09/2025 ciprofloxacin hydrochloride Tablet, film coated 555 mg Current Unavailable Manufacturing 4/09/2025 phenobarbital Tablet, uncoated 30 mg Anticipated Available Manufacturing 4/09/2025 quetiapine fumarate Tablet, modified release 172.695 mg Anticipated Available Manufacturing 4/09/2025 salmeterol xinafoate~fluticasone propionate Inhalation, pressurised 36.3 microgram/actuation~125 microgram/actuation Anticipated Available Unexpected increase in consumer demand 4/09/2025 ropinirole hydrochloride Tablet, film coated .285 mg Current Limited Availability Manufacturing 4/09/2025 oxaliplatin Injection, concentrated 100 mg Current Limited Availability Manufacturing 4/09/2025 lacosamide Tablet, film coated 100 mg Current Limited Availability Manufacturing 4/09/2025 GluureaLys(ahx)hbedCC Injection, powder for 25 microgram Current Unavailable Manufacturing 4/09/2025 midazolam Injection, solution 1 mg/mL Current Limited Availability Manufacturing 4/09/2025 estradiol hemihydrate Drug delivery system, transdermal 2.32 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 4/09/2025 sodium valproate Tablet, uncoated 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 3/09/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 3/09/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 3/09/2025 praziquantel Tablet, film coated 600 mg Discontinued Reduction in supply until supply is exhausted Manufacturing 3/09/2025 ciprofloxacin hydrochloride Tablet, film coated 832.5 mg Current Unavailable Manufacturing 3/09/2025 leuprorelin acetate~bicalutamide Injection, modified release~Tablet, film coated 7.5 mg~50 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 3/09/2025 allopurinol Tablet, uncoated 100 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/09/2025 tadalafil Tablet, film coated 5 mg Current Limited Availability Manufacturing 3/09/2025 fluorouracil Injection, solution 50 mg/mL Current Unavailable Manufacturing 3/09/2025 metaraminol tartrate Injection, solution 19 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 3/09/2025 ramipril Tablet, uncoated 1.25 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 3/09/2025 sitagliptin hydrochloride monohydrate~metformin hydrochloride Tablet, film coated 56.69 mg~1000 mg Current Unavailable Manufacturing 3/09/2025 framycetin sulfate Eye and Ear Drops 5 mg/mL Current Limited Availability Transport / Logistic issues / Storage capacity issues 3/09/2025 imipramine hydrochloride Tablet, sugar coated 25 mg Current Unavailable Manufacturing 3/09/2025 pantoprazole sodium sesquihydrate Tablet, enteric coated 45.4 mg Current Limited Availability Unexpected increase in consumer demand 2/09/2025 midazolam Injection, solution 5 mg Current Limited Availability Manufacturing 2/09/2025 doxorubicin hydrochloride Injection, concentrated 2 mg/mL Resolved Available Manufacturing 2/09/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in consumer demand 2/09/2025 rosuvastatin calcium Tablet, film coated 41.68 mg Current Limited Availability Manufacturing 2/09/2025 pregabalin Capsule, hard 75 mg Current Limited Availability Manufacturing 2/09/2025 levetiracetam Solution 100 mg/mL Anticipated Available Manufacturing 2/09/2025 clonidine hydrochloride Tablet 100 microgram Current Limited Availability Unexpected increase in consumer demand 2/09/2025 solifenacin succinate Tablet 10 mg Resolved Available Manufacturing 2/09/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Current Unavailable Manufacturing 2/09/2025 moxonidine Tablet, film coated 400 microgram Anticipated Available Commercial Changes / Commercial viability 2/09/2025 moxonidine Tablet, film coated 200 microgram Anticipated Available Commercial Changes / Commercial viability 2/09/2025 dabigatran etexilate mesilate Capsule, hard 172.95 mg Current Unavailable Manufacturing 2/09/2025 teriflunomide Tablet, film coated 14 mg Current Limited Availability Manufacturing 2/09/2025 amiodarone hydrochloride Tablet, uncoated 100 mg Current Unavailable Manufacturing 2/09/2025 spironolactone Tablet, uncoated 25 mg Current Unavailable Manufacturing 2/09/2025 spironolactone Tablet, uncoated 100 mg Current Limited Availability Manufacturing 2/09/2025 flecainide acetate Tablet 50 mg Current Unavailable Manufacturing 2/09/2025 sacubitril~valsartan Tablet, film coated 48.6 mg~51.4 mg Current Unavailable Manufacturing 2/09/2025 sacubitril~valsartan Tablet, film coated 97.2 mg~102.8 mg Current Unavailable Manufacturing 2/09/2025 sugammadex sodium Injection, solution 217.6 mg Current Limited Availability Manufacturing 2/09/2025 tetrabenazine Tablet, uncoated 25 mg Current Limited Availability Manufacturing 2/09/2025 rifampicin Capsule, hard 150 mg Current Limited Availability Manufacturing 2/09/2025 rocuronium bromide Injection, solution 50 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 1/09/2025 dopamine hydrochloride Injection, concentrated 40 mg/mL Resolved Available Unexpected increase in consumer demand 1/09/2025 propranolol hydrochloride Tablet, film coated 40 mg Current Unavailable Manufacturing 1/09/2025 meloxicam Capsule, hard 7.5 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 1/09/2025 meloxicam Capsule, hard 15 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 1/09/2025 atorvastatin calcium trihydrate~ezetimibe Tablet, multilayer 10.9 mg~10 mg Current Limited Availability Manufacturing 1/09/2025 prochlorperazine maleate Tablet, uncoated 5 mg Current Unavailable Commercial Changes / Commercial viability 1/09/2025 celecoxib Capsule, hard 100 mg Resolved Available Manufacturing 1/09/2025 atovaquone~proguanil hydrochloride Tablet, film coated 250 mg~100 mg Current Limited Availability Manufacturing 1/09/2025 stannous chloride dihydrate Injection, powder for 19.2 microgram/mL Current Limited Availability Manufacturing 1/09/2025 citalopram hydrobromide Tablet, film coated 49.96 mg Current Unavailable Manufacturing 1/09/2025 galantamine~galantamine hydrobromide Capsule, modified release 16 mg~20.51 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 1/09/2025 - 2025.09.01
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated methylphenidate hydrochloride Tablet, uncoated 10 mg Resolved Available Manufacturing 29/08/2025 lincomycin hydrochloride monohydrate Injection, solution 340.26 mg/mL Discontinued Unavailable Commercial Changes / Commercial viability 29/08/2025 risperidone Tablet, film coated 1 mg Current Unavailable Manufacturing 29/08/2025 midazolam Injection, solution 5 mg/mL Current Limited Availability Manufacturing 29/08/2025 olanzapine pamoate monohydrate Injection, powder for 483 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 29/08/2025 benzathine benzylpenicillin tetrahydrate Injection, suspension 1200000 USP Unit Current Limited Availability Manufacturing 29/08/2025 galantamine hydrobromide Capsule, modified release 20.512 mg Current Unavailable Manufacturing 29/08/2025 galantamine hydrobromide Capsule, modified release 30.768 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 29/08/2025 midazolam Injection, solution 50 mg Current Limited Availability Manufacturing 29/08/2025 vecuronium bromide Injection, powder for 10 mg Anticipated Available Manufacturing 29/08/2025 Somatropin Injection, powder for 12 mg/mL Anticipated Available Unexpected increase in consumer demand 29/08/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.9 mg Current Unavailable Unexpected increase in consumer demand 29/08/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 29/08/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 29/08/2025 ketorolac trometamol Injection, solution 30 mg/mL Discontinued Unavailable Commercial Changes / Commercial viability 29/08/2025 cisatracurium besilate Injection, solution 7.04 mg Anticipated Available Manufacturing 29/08/2025 lamotrigine Tablet, uncoated 200 mg Current Limited Availability Manufacturing 29/08/2025 cyproterone acetate Tablet, uncoated 50 mg Current Limited Availability Manufacturing 29/08/2025 atorvastatin calcium trihydrate Tablet, film coated 10.845 mg Resolved Available Manufacturing 29/08/2025 moxonidine Tablet, film coated 400 microgram Anticipated Available Commercial Changes / Commercial viability 29/08/2025 moxonidine Tablet, film coated 200 microgram Anticipated Available Commercial Changes / Commercial viability 29/08/2025 posaconazole Tablet, modified release 100 mg Current Unavailable Manufacturing 29/08/2025 mesalazine Tablet, enteric coated 1.6 g Resolved Available Transport / Logistic issues / Storage capacity issues 29/08/2025 midazolam maleate Solution 10.2 mg Current Limited Availability Manufacturing 29/08/2025 lorazepam Tablet 1 mg Current Limited Availability Manufacturing 29/08/2025 tamoxifen citrate Tablet, uncoated 15.2 mg Current Unavailable Manufacturing 29/08/2025 tamoxifen citrate Tablet, uncoated 30.4 mg Current Unavailable Manufacturing 29/08/2025 trandolapril Capsule, hard 2 mg Current Unavailable Manufacturing 29/08/2025 lidocaine hydrochloride monohydrate Injection, solution 10 mg/mL Current Limited Availability Manufacturing 29/08/2025 terbinafine hydrochloride Tablet, uncoated 281.25 mg Current Limited Availability Manufacturing 28/08/2025 live varicella vaccine Injection, powder for 2700 PFU/mL Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 28/08/2025 glimepiride Tablet, uncoated 1 mg Current Unavailable Manufacturing 28/08/2025 risperidone Tablet, film coated 2 mg Current Unavailable Manufacturing 28/08/2025 risperidone Tablet, film coated 3 mg Current Unavailable Manufacturing 28/08/2025 topiramate Tablet, film coated 25 mg Current Limited Availability Manufacturing 28/08/2025 ciprofloxacin hydrochloride Tablet, film coated 277.5 mg Current Unavailable Manufacturing 28/08/2025 lamotrigine Tablet, chewable 200 mg Current Limited Availability Manufacturing 28/08/2025 fentanyl Drug delivery system, transdermal 16.8 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 28/08/2025 risperidone Tablet, film coated 2 mg Anticipated Available Manufacturing 28/08/2025 bisoprolol fumarate Tablet 2.5 mg Anticipated Available Manufacturing 28/08/2025 pioglitazone hydrochloride Tablet, uncoated 49.59 mg Resolved Available Manufacturing 28/08/2025 mycophenolate mofetil Capsule 250 mg Resolved Available Manufacturing 28/08/2025 levetiracetam Tablet, film coated 500 mg Anticipated Available Manufacturing 28/08/2025 ondansetron hydrochloride dihydrate Tablet, film coated 9.972 mg Current Limited Availability Manufacturing 28/08/2025 metronidazole Tablet, uncoated 400 mg Current Limited Availability Manufacturing 28/08/2025 galantamine hydrobromide Capsule, modified release 10.252 mg Current Unavailable Manufacturing 28/08/2025 montelukast sodium Tablet, chewable 5.2 mg Current Unavailable Unexpected increase in consumer demand 28/08/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 28/08/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 28/08/2025 sumatriptan succinate Tablet, film coated 69.99 mg Anticipated Available Manufacturing 28/08/2025 finasteride Tablet, film coated 1 mg Current Unavailable Manufacturing 28/08/2025 ciprofloxacin hydrochloride Tablet, film coated 277.5 mg Current Unavailable Manufacturing 28/08/2025 ciprofloxacin hydrochloride Tablet, film coated 555 mg Current Unavailable Manufacturing 28/08/2025 trandolapril Capsule, hard 1 mg Current Unavailable Manufacturing 28/08/2025 trandolapril Capsule, hard 2 mg Current Unavailable Manufacturing 28/08/2025 trandolapril Capsule, hard 4 mg Current Unavailable Manufacturing 28/08/2025 lansoprazole Tablet, orally disintegrating 15 mg Anticipated Available Manufacturing 28/08/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Limited Availability Manufacturing 28/08/2025 citalopram hydrobromide Tablet, film coated 49.98 mg Current Limited Availability Manufacturing 28/08/2025 linezolid Tablet, film coated 600 mg Current Unavailable Manufacturing 28/08/2025 anastrozole Tablet, film coated 1 mg Current Unavailable Manufacturing 28/08/2025 solifenacin succinate Tablet 10 mg Current Unavailable Manufacturing 28/08/2025 irbesartan Tablet, film coated 300 mg Resolved Available Manufacturing 28/08/2025 hydrochlorothiazide~irbesartan Tablet, film coated 12.5 mg~300 mg Current Unavailable Manufacturing 28/08/2025 tadalafil Tablet, film coated 20 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 28/08/2025 nizatidine Capsule, hard 150 mg Current Unavailable Manufacturing 28/08/2025 acamprosate calcium Tablet, enteric coated 333 mg Current Unavailable Manufacturing 28/08/2025 bimatoprost Eye Drops .3 mg/mL Anticipated Available Manufacturing 28/08/2025 phenytoin sodium Capsule, hard 30 mg Current Limited Availability Manufacturing 28/08/2025 ropinirole hydrochloride Tablet, film coated .285 mg Anticipated Available Manufacturing 28/08/2025 metaraminol tartrate Injection, solution 19 mg Current Limited Availability Manufacturing 28/08/2025 atorvastatin calcium trihydrate Tablet, film coated 43.376 mg Resolved Available Manufacturing 28/08/2025 atorvastatin calcium trihydrate Tablet, film coated 43.376 mg Resolved Available Manufacturing 28/08/2025 flucloxacillin sodium monohydrate Injection, powder for 544.1 mg Resolved Available Transport / Logistic issues / Storage capacity issues 28/08/2025 lamotrigine Tablet, chewable 100 mg Anticipated Available Manufacturing 28/08/2025 buprenorphine hydrochloride Tablet, uncoated .216 mg Resolved Available Manufacturing 28/08/2025 hyoscine butylbromide Injection, solution 20 mg Current Limited Availability Manufacturing 28/08/2025 sugammadex sodium Injection, solution 217.6 mg Current Limited Availability Manufacturing 28/08/2025 naltrexone hydrochloride Tablet, film coated 50 mg Anticipated Available Manufacturing 28/08/2025 rivaroxaban Tablet, film coated 10 mg Anticipated Available Manufacturing 28/08/2025 metformin hydrochloride~sitagliptin hydrochloride monohydrate Tablet, film coated 500 mg~56.69 mg Resolved Available Manufacturing 28/08/2025 metformin hydrochloride~sitagliptin hydrochloride monohydrate Tablet, film coated 850 mg~56.69 mg Resolved Available Manufacturing 28/08/2025 carboplatin Injection, solution 10 mg/mL Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 28/08/2025 phenytoin sodium Injection, solution 250 mg Anticipated Available Manufacturing 28/08/2025 silver sulfadiazine Cream 10 mg/g Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 27/08/2025 silver sulfadiazine Cream 10 mg/g Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 27/08/2025 doxylamine succinate Tablet, uncoated 25 mg Current Limited Availability Unexpected increase in consumer demand 27/08/2025 docetaxel Injection, concentrated 80 mg Anticipated Available Manufacturing 27/08/2025 azacitidine Injection, powder for 100 mg Current Limited Availability Manufacturing 27/08/2025 metronidazole Injection, solution 500 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 27/08/2025 sertraline hydrochloride Tablet, film coated 112 mg Current Limited Availability Commercial Changes / Commercial viability 26/08/2025 sodium pyrophosphate Injection, powder for 30 mg Current Unavailable Manufacturing 26/08/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Emergency Supply Only Unexpected increase in demand due to other sponsors unable to supply 26/08/2025 pantoprazole sodium sesquihydrate Tablet, enteric coated 45.4 mg Current Limited Availability Unexpected increase in consumer demand 26/08/2025 sulfamethoxazole~trimethoprim Injection, concentrated 80 mg/mL~16 mg/mL Current Limited Availability Manufacturing 26/08/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.9 mg Current Limited Availability Unexpected increase in consumer demand 26/08/2025 sulfamethoxazole~trimethoprim Tablet, uncoated 800 mg~160 mg Current Limited Availability Manufacturing 26/08/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 26/08/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in consumer demand 26/08/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 26/08/2025 clopidogrel besilate Tablet, film coated 112.1 mg Current Unavailable Manufacturing 26/08/2025 midazolam hydrochloride Injection, solution 5.56 mg/mL Current Unavailable Commercial Changes / Commercial viability 26/08/2025 rosuvastatin calcium Tablet, film coated 10.42 mg Current Unavailable Manufacturing 26/08/2025 pregabalin Capsule, hard 150 mg Current Limited Availability Manufacturing 26/08/2025 pregabalin Capsule, hard 75 mg Current Unavailable Manufacturing 26/08/2025 daptomycin Injection, powder for 350 mg Resolved Available Manufacturing 26/08/2025 topotecan hydrochloride Injection, concentrated 4.346 mg Current Limited Availability Unexpected increase in consumer demand 26/08/2025 paclitaxel Injection, powder for 100 mg Current Unavailable Manufacturing 26/08/2025 metoprolol succinate Tablet, modified release 47.5 mg Current Unavailable Manufacturing 26/08/2025 daptomycin Injection, powder for 500 mg Current Unavailable Manufacturing 26/08/2025 daptomycin Inhalation, powder for 350 mg Current Unavailable Manufacturing 26/08/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 26/08/2025 indocyanine green Injection, powder for 25 mg Current Unavailable Manufacturing 26/08/2025 labetalol hydrochloride Tablet, film coated 100 mg Current Limited Availability Manufacturing 26/08/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 26/08/2025 betiatide Injection, powder for 1 mg Resolved Available Manufacturing 25/08/2025 irinotecan hydrochloride trihydrate Injection, concentrated 100 mg Resolved Available Manufacturing 25/08/2025 carboplatin Injection, solution 450 mg Current Limited Availability Manufacturing 25/08/2025 articaine hydrochloride~adrenaline (epinephrine) acid tartrate Injection, solution 40 mg/mL~18.2 microgram/mL Current Unavailable Transport / Logistic issues / Storage capacity issues 25/08/2025 escitalopram oxalate Tablet, film coated 12.74 mg Current Unavailable Commercial Changes / Commercial viability 25/08/2025 methylphenidate hydrochloride Capsule, hard 20 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 25/08/2025 carboplatin Injection, solution 450 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 25/08/2025
ドイツ
- 2025.09.28
Active ingredients Message type Date of last message Type of reason AM designation Tinzaparin sodium Initial report 26.09.2025 Production problem innohep 4,500 Anti-Xa I.E. Solution for injection Paliperidone palmitate Change notification 26.09.2025 Other XEPLION 25 mg prolonged-release suspension for injection – OP1ml Quetiapine fumarate (Ph.Eur.) Change notification 26.09.2025 Other Seroquel Prolong 400 mg prolonged-release tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 25.09.2025 Other Atorvastatin Micro Labs 80 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 25.09.2025 Other Atorvastatin Micro Labs 40 mg film-coated tablets Aprepitant Initial report 25.09.2025 Other Aprepitant AL 125 mg and 80 mg hard capsules Isosorbide mononitrate Change notification 25.09.2025 Other ISMN AL40 retard Isosorbide mononitrate Change notification 25.09.2025 Other ISMN AL 100 retard Quetiapine fumarate (Ph.Eur.) Change notification 25.09.2025 Other Quetiapine AL 200 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 25.09.2025 Other Quetiapine AL 300 mg film-coated tablets Quetiapine fumarate (Ph.Eur.) Change notification 25.09.2025 Other Quetiapine AL 300 mg prolonged-release tablets Phenylephrine hydrochloride Change notification 25.09.2025 Production problem Neosynephrine-POS 5% Aprepitant Change notification 25.09.2025 Other Aprepitant AL 80 mg hard capsules Aprepitant Change notification 25.09.2025 Other Aprepitant AL 125 mg hard capsules Epirubicin hydrochloride Change notification 25.09.2025 Production problem Epirubicin Hikma 2 mg/ml concentrate for solution for infusion Rivastigmine hydrogen tartrate Change notification 25.09.2025 Production problem Rivastigmine Aurobindo 6 mg hard capsules Liraglutide Change notification 25.09.2025 Other Saxenda 6 mg/ml solution for injection in pre-filled pen – OP(5x3ml) Liraglutide Change notification 25.09.2025 Other Saxenda 6 mg/ml solution for injection in pre-filled pen – OP(3x3ml) Insulin aspart Initial report 24.09.2025 Production problem Fiasp Semaglutide Initial report 24.09.2025 Production problem Ozempic 0.5 mg solution for injection in a pre-filled pen – OP1.5 ml Progesterone Initial report 24.09.2025 Production problem LUTINUS 100 mg vaginal tablets Sodium perchlorate 1 H<2>O Change notification 24.09.2025 Other Irenat drops Rifampicin sodium Change notification 24.09.2025 Production problem Eremfat i.v. 300mg Methylphenidate hydrochloride Change notification 24.09.2025 Other Methylphenidate AL 27 mg prolonged-release tablets Azithromycin dihydrate Change notification 24.09.2025 Other Azithromycin AL 250 mg film-coated tablets Quetiapine fumarate (Ph.Eur.) Change notification 24.09.2025 Other Seroquel Prolong 150 mg prolonged-release tablets Clomipramine hydrochloride Change notification 23.09.2025 Production problem Anafranil 75mg prolonged-release Vibegron Initial report 23.09.2025 Production problem Obgemsa Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 23.09.2025 Other Atorvastatin Micro Labs 60 mg film-coated tablets Sevelamer Change notification 23.09.2025 Other Renagel 800 mg film-coated tablets – OP(1×180) Trimipramine mesylate Change notification 23.09.2025 Other Trimipramine – 1 A Pharma 40 mg/ml oral drops, solution Oxcarbazepine Change notification 23.09.2025 Other Oxcarbazepine – 1 A Pharma 60 mg/ml oral suspension Atomoxetine hydrochloride Change notification 23.09.2025 Other Atomoxe – 1 A Pharma 80 mg hard capsules Atomoxetine hydrochloride Change notification 23.09.2025 Other Atomoxe – 1 A Pharma 60 mg hard capsules Atomoxetine hydrochloride Change notification 23.09.2025 Other Atomoxe – 1 A Pharma 40 mg hard capsules Atomoxetine hydrochloride Change notification 23.09.2025 Other Atomoxe – 1 A Pharma 25 mg hard capsules Atomoxetine hydrochloride Change notification 23.09.2025 Other Atomoxe – 1 A Pharma 18 mg hard capsules Atomoxetine hydrochloride Change notification 23.09.2025 Other Atomoxe – 1 A Pharma 100 mg hard capsules Atomoxetine hydrochloride Change notification 23.09.2025 Other Atomoxe – 1 A Pharma 10 mg hard capsules Fosfomycin sodium (Ph.Eur.) Change notification 23.09.2025 Production problem Fosfomycin Eberth 4 g powder for solution for infusion Fosfomycin sodium (Ph.Eur.) Change notification 23.09.2025 Production problem Fosfomycin Eberth 2 g powder for solution for infusion Hydrocortisone Initial report 22.09.2025 Production problem Alkindi 5 mg granules for removal from capsule – OP50 Domperidone Change notification 22.09.2025 Production problem Motilium drops 10 mg/ml suspension Naloxone hydrochloride dihydrate; oxycodone hydrochloride (Ph.Eur.) Change notification 22.09.2025 Production problem Oxycodone/naloxone Krugmann 20 mg/10 mg prolonged-release tablets Naloxone hydrochloride dihydrate; oxycodone hydrochloride (Ph.Eur.) Change notification 22.09.2025 Production problem Oxycodone / Naloxone Krugmann 40 mg/20 mg prolonged-release tablets Oxycodone hydrochloride Change notification 22.09.2025 Other OXYGESIC 10 mg Hydromorphone hydrochloride Change notification 22.09.2025 Production problem Palladon inject 20 mg/ml solution for injection/infusion Calcium chloride dihydrate; histidine; histidine hydrochloride monohydrate; potassium hydrogen 2-oxopentanedioate; potassium chloride; magnesium chloride hexahydrate; mannitol (Ph.Eur.); sodium chloride; tryptophan Change notification 22.09.2025 Production problem Custodiol Beclomethasone dipropionate (Ph.Eur.) Change notification 22.09.2025 Other Beclorhinol aquosum 50 micrograms Imiquimod Initial report 22.09.2025 Production problem Imikeraderm 50 mg/g cream Trandolapril; verapamil hydrochloride Initial report 22.09.2025 Other Tarka 240 mg/4 mg modified-release tablets - 2025.09.22
Paliperidone palmitate Initial report 19.09.2025 Other XEPLION 25 mg depot injection suspension – OP1ml Beclomethasone dipropionate (Ph.Eur.) Change notification 19.09.2025 Other Beclorhinol aquosum 50 micrograms Quetiapine fumarate (Ph.Eur.) Initial report 19.09.2025 Other Seroquel Prolong 200 mg prolonged-release tablets Olanzapine embonate monohydrate Change notification 19.09.2025 Production problem ZYPADHERA 405 mg powder and solvent for the preparation of a prolonged-release suspension for injection – OP(931mg+3ml) Paliperidone palmitate Change notification 19.09.2025 Production problem Paliperidone Advanz Pharma 50 mg prolonged-action injection suspension in a pre-filled syringe Paliperidone palmitate Change notification 19.09.2025 Production problem Paliperidone Advanz Pharma 25 mg prolonged-release injection suspension in a pre-filled syringe Naloxegol oxalate Change notification 19.09.2025 Other Moventig 25 mg film-coated tablets – OP100(100×1) Naloxone hydrochloride dihydrate; oxycodone hydrochloride monohydrate Initial report 19.09.2025 Production problem Targin 60 mg/30 mg prolonged-release tablets Oxycodone hydrochloride Change notification 18.09.2025 Other OXYGESIC 10 mg Ciprofloxacin hydrochloride monohydrate Change notification 18.09.2025 Other CIPRO BASICS 250 mg film-coated tablets Ciprofloxacin hydrochloride monohydrate Initial report 18.09.2025 Other CIPRO BASICS 750 mg film-coated tablets Flecainide acetate Change notification 18.09.2025 Other Tambocor Tobramycin Change notification 18.09.2025 Production problem TOBI Podhaler 28 mg hard capsules with powder for inhalation – OP224(4×56) Azithromycin dihydrate Change notification 18.09.2025 Other Azithromycin AL 250 mg film-coated tablets Clonidine hydrochloride Initial report 18.09.2025 Production problem Clonistada 0.15 mg tablets Ipratropium bromide (Ph.Eur.) Change notification 18.09.2025 Production problem Ipratropium Teva 250 micrograms/1 ml solution for nebulizer Galantamine hydrobromide Change notification 18.09.2025 Other Galantamine-ratiopharm 8 mg hard capsules, delayed release Rizatriptan benzoate Change notification 17.09.2025 Production problem Rizatriptan Glenmark 5 mg tablets Rizatriptan benzoate Change notification 17.09.2025 Production problem Rizatriptan Glenmark 5 mg orodispersible tablets Rizatriptan benzoate Change notification 17.09.2025 Production problem Rizatriptan Glenmark 10 mg orodispersible tablets Rizatriptan benzoate Change notification 17.09.2025 Production problem Rizatriptan Glenmark 10 mg tablets Quetiapine fumarate (Ph.Eur.) Change notification 17.09.2025 Production problem Quetiapine Glenmark 200 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Initial report 17.09.2025 Production problem Quetiapine Glenmark 300 mg prolonged-release tablets Mometasone furoate (Ph.Eur.) Change notification 17.09.2025 Production problem Mometasone Glenmark 1 mg/g ointment Linezolid Change notification 17.09.2025 Production problem Linezolid Glenmark 600 mg film-coated tablets Nitrendipine Initial report 17.09.2025 Other Nitrendipine AbZ 20 mg tablets Nitrendipine Initial report 17.09.2025 Other Nitrendipine AbZ 10 mg tablets Nitrendipine Initial report 17.09.2025 Other Nitrendipine-ratiopharm 20 mg tablets Nitrendipine Initial report 17.09.2025 Other Nitrendipine-ratiopharm 10 mg tablets Nitrendipine Initial report 17.09.2025 Other Nitrendipine AL 20 Nitrendipine Initial report 17.09.2025 Other Nitrendipine AL 10 Misoprostol Initial report 17.09.2025 Other Angusta 25 microgram tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 17.09.2025 Other Atorvastatin Aristo 60 mg film-coated tablets Trandolapril Change notification 17.09.2025 Other Udrik 0.5 mg Fluoxetine hydrochloride Change notification 16.09.2025 Other Fluoxetine Micro Labs 10 mg hard capsules Fluoxetine hydrochloride Change notification 16.09.2025 Other Fluoxetine Micro Labs 20 mg hard capsules Fluoxetine hydrochloride Change notification 16.09.2025 Other Fluoxetine Micro Labs 30 mg hard capsules Fluoxetine hydrochloride Change notification 16.09.2025 Other Fluoxetine Micro Labs 40 mg hard capsules Fluoxetine hydrochloride Change notification 16.09.2025 Other Fluoxetine Micro Labs 60 mg hard capsules Aprepitant Change notification 16.09.2025 Other Aprepitant AL 125 mg hard capsules Rifampicin sodium Initial report 16.09.2025 Production problem Eremfat IV 300 mg Trandolapril; verapamil hydrochloride Change notification 16.09.2025 Other Tarka 180 mg/2 mg modified-release tablets Sufentanil citrate Change notification 15.09.2025 Production problem Sufenta 50 micrograms/ml solution for injection Isosorbide mononitrate Change notification 15.09.2025 Production problem ISMN STADA 20 mg tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 15.09.2025 Production problem Atorvastatin STADA 80 mg film-coated tablets Aprepitant Change notification 15.09.2025 Production problem Aprepitant STADA 125 mg hard capsules Doxylamine hydrogen succinate Change notification 15.09.2025 Production problem Hoggar Night 25 mg orodispersible tablets Flucloxacillin sodium 1 H<2>O Change notification 15.09.2025 Production problem Staphylex 250 mg capsules - 2025.09.15
Active ingredients Message type Date of last message Type of reason AM designation Hydrated dihydralazine sulfate (Ph.Eur.) Initial report 12.09.2025 Production problem Nepresol Doxepin hydrochloride (Ph.Eur.) Change notification 12.09.2025 Production problem Doxepin 75 Holsten Prednisolone acetate Change notification 12.09.2025 Production problem Predni-Ophtal Gel Indapamide; Perindopril arginine Initial report 12.09.2025 Other Perindopril arginine/indapamide Viatris 5 mg/1.25 mg film-coated tablets Indapamide; Perindopril tert-butylamine Initial report 12.09.2025 Other Perindopril-dura plus 2 mg/0.625 mg tablets Amantadine hemisulfate Change notification 12.09.2025 Other PK-Merz Infusion Trandolapril Initial report 12.09.2025 Other Udrik 0.5 mg Rosuvastatin calcium (Ph.Eur.) Initial report 11.09.2025 Other Rosuvastatin Aurobindo 20 mg film-coated tablets Atomoxetine hydrochloride Initial report 11.09.2025 Other Atomoxetine PUREN 10 mg hard capsules Atomoxetine hydrochloride Initial report 11.09.2025 Production problem Atomoxetine PUREN 80 mg hard capsules Amlodipine besylate; telmisartan Initial report 11.09.2025 Production problem TWYNSTA 80 mg/10 mg tablets – OP98 Amlodipine besylate; telmisartan Initial report 11.09.2025 Production problem TWYNSTA 40 mg/5 mg tablets – OP98 Terazosin hydrochloride dihydrate Change notification 11.09.2025 Other Heitrin 2mg Terazosin hydrochloride dihydrate Change notification 11.09.2025 Other Heitrin 5mg Terazosin hydrochloride dihydrate Change notification 11.09.2025 Other Heitrin 1 mg Oxazepam Change notification 11.09.2025 Other Oxazepam AL 10 Paliperidone palmitate Change notification 11.09.2025 Other Paliperidone AL 25 mg Depot injection suspension in a pre-filled syringe Azithromycin dihydrate Change notification 11.09.2025 Other Azithromycin AL 250 mg film-coated tablets Hydromorphone hydrochloride Change notification 11.09.2025 Other Hydromorphone PAINBREAK 4 mg prolonged-release tablets Hydromorphone hydrochloride Change notification 11.09.2025 Other Hydromorphone PAINBREAK 8 mg prolonged-release tablets Dexketoprofen trometamol Change notification 10.09.2025 Production problem Sympal inject 50 mg solution for injection/infusion Adenosine Initial report 09.09.2025 Production problem Adenosine Altamedics 3 mg/ml solution for injection Imiquimod Initial report 09.09.2025 Production problem Aldara 5% cream – OP24 Atorvastatin calcium trihydrate (Ph.Eur.) Initial report 09.09.2025 Other Sortis 20 mg chewable tablets Verteporfin Change notification 09.09.2025 Other Visudyne 15 mg powder for solution for infusion – OP1 Clonidine hydrochloride Initial report 09.09.2025 Other Clonidine-ratiopharm 300 Clonidine hydrochloride Initial report 09.09.2025 Other Clonidine-ratiopharm 150 Clonidine hydrochloride Initial report 09.09.2025 Other Clonidine-ratiopharm 75 Methylphenidate hydrochloride Change notification 09.09.2025 Other Methylphenidate-ratiopharm 40 mg hard capsules with modified release Methylphenidate hydrochloride Change notification 09.09.2025 Other Methylphenidate-ratiopharm 20 mg hard capsules with modified release Methylphenidate hydrochloride Initial report 09.09.2025 Other Methylphenidate-ratiopharm 30 mg hard capsules with modified release Methylphenidate hydrochloride Initial report 09.09.2025 Other Methylphenidate-ratiopharm 10 mg modified-release hard capsules Duloxetine Initial report 09.09.2025 Other Duloxetine Mylan 30 mg gastro-resistant hard capsules – OP100(Fl) Duloxetine Initial report 09.09.2025 Other Duloxetine Mylan 60 mg gastro-resistant hard capsules – OP100(Fl) Procaine hydrochloride Change notification 09.09.2025 Other Procaine 2% JENAPHARM Procaine hydrochloride Change notification 09.09.2025 Other Procaine 1% JENAPHARM Pramipexole dihydrochloride monohydrate Change notification 08.09.2025 Other Pramipexole – 1 A Pharma 0.52 mg prolonged-release tablets Sodium mycophenolate Change notification 08.09.2025 Other Mycophenolic acid HEXAL 360 mg gastro-resistant tablets Atomoxetine hydrochloride Change notification 08.09.2025 Production problem Atomoxetine beta 18 mg hard capsules Atomoxetine hydrochloride Change notification 08.09.2025 Production problem Atomoxetine beta 100 mg hard capsules Naloxone hydrochloride dihydrate; oxycodone hydrochloride (Ph.Eur.) Initial report 08.09.2025 Production problem Oxycodone/naloxone Krugmann 40 mg/20 mg prolonged-release tablets Naloxone hydrochloride dihydrate; oxycodone hydrochloride (Ph.Eur.) Initial report 08.09.2025 Production problem Oxycodone / Naloxone Krugmann 20 mg/10 mg prolonged-release tablets Oxycodone hydrochloride (Ph.Eur.) Change notification 08.09.2025 Production problem Oxygesic 5 mg Rosuvastatin Hemicalcium Change notification 08.09.2025 Other ROSUVASTATIN-ELPEN 40 mg film-coated tablets Rosuvastatin Hemicalcium Change notification 08.09.2025 Other ROSUVASTATIN-ELPEN 20 mg film-coated tablets Rosuvastatin Hemicalcium Change notification 08.09.2025 Other ROSUVASTATIN-ELPEN 10 mg film-coated tablets Rosuvastatin Hemicalcium Change notification 08.09.2025 Other ROSUVASTATIN-ELPEN 5 mg film-coated tablets Hydromorphone hydrochloride Initial report 08.09.2025 Production problem Palladon inject 20 mg/ml solution for injection/infusion Hydromorphone hydrochloride Initial report 08.09.2025 Production problem Palladon 2.6 mg hard capsules Oxycodone hydrochloride (Ph.Eur.) Change notification 08.09.2025 Other Oxygesic 5 mg Oxycodone hydrochloride Change notification 08.09.2025 Other OXYGESIC 10 mg Sugammadex sodium Change notification 08.09.2025 Production problem Sugammadex Amomed - 2025.09.08
Active ingredients Message type Date of last message Type of reason AM designation Amantadine hemisulfate Change notification 05.09.2025 Other PK-Merz Infusion Sodium (methylprednisolone-21-succinate) Change notification 05.09.2025 Other Urbason soluble forte 1000 mg Ipratropium bromide (Ph.Eur.); salbutamol sulfate Change notification 05.09.2025 Production problem COMBIPRASAL 0.5 mg / 2.5 mg solution for nebulizer Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y) Change notification 05.09.2025 Other Ferrlecit 40 mg Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y) Change notification 05.09.2025 Other Ferrlecit 62.5 mg Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 05.09.2025 Other Atorvastatin Micro Labs 10 mg film-coated tablets Esomeprazole hemimagnesium Change notification 04.09.2025 Production problem ESOMEPRAZOLE BASICS 20 mg gastro-resistant hard capsules Carbamazepine Initial report 04.09.2025 Production problem Tegretal 400 mg retard Olanzapine embonate monohydrate Change notification 04.09.2025 Production problem ZYPADHERA 300 mg powder and solvent for the preparation of a depot injection suspension – OP(690mg+3ml) Olanzapine Change notification 04.09.2025 Production problem Zyprexa 7.5 mg coated tablets – OP70(blister) Olanzapine Initial report 04.09.2025 Production problem ZYPREXA Olanzapine embonate monohydrate Change notification 04.09.2025 Production problem ZYPADHERA 405 mg powder and solvent for the preparation of a depot injection suspension – OP(931mg+3ml) Human insulin (with manufacturing information) Initial report 04.09.2025 Other Huminsulin Basal (NPH) for Pen 3 ml 100 IU/ml injection suspension in cartridge Betamethasone dipropionate (Ph.Eur.); gentamicin sulfate Initial report 04.09.2025 Other Diprogenta cream Methylphenidate hydrochloride Initial report 04.09.2025 Other Methylphenidate AL 36 mg prolonged-release tablets Paliperidone palmitate Change notification 04.09.2025 Other Paliperidone AL 50 mg depot injection suspension in a pre-filled syringe Insulin lispro Initial report 03.09.2025 Other Liprolog Mix50 100 /ml KwikPen injection suspension – OP[2x(5x3ml)] Human insulin (with manufacturing information) Initial report 03.09.2025 Other Huminsulin Basal (NPH) KwikPen 100 IU/ml injection suspension Fluorouracil Change notification 03.09.2025 Other Fluorouracil PhaRes 50 mg/ml solution for injection Phenytoin sodium Change notification 03.09.2025 Production problem Phenhydan Injection solution Methyl (5-amino-4-oxopentanoate) hydrochloride Change notification 03.09.2025 Other Metvix 160 mg/g cream Monosodium alendronate Change notification 03.09.2025 Other ALENDRONIC ACID BASICS once weekly 70 mg tablets Pramipexole dihydrochloride monohydrate Change notification 03.09.2025 Other Pramipexole-ratiopharm 0.26 mg prolonged-release tablets Dexamethasone; gentamicin sulfate Initial report 03.09.2025 Production problem Dexa-Gentamicin Gentamicin sulfate Change notification 03.09.2025 Production problem Gentamicin POS Ezetimibe; simvastatin Initial report 02.09.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/80 mg tablets Ezetimibe; simvastatin Initial report 02.09.2025 Production problem EZETIMIBE/SIMVA BASICS 10 mg/40 mg tablets Ezetimibe; simvastatin Initial report 02.09.2025 Production problem EZETIMIBE/SIMVA BASICS 10 mg/20 mg tablets Ezetimibe; simvastatin Initial report 02.09.2025 Production problem EZETIMIBE/SIMVA BASICS 10 mg/10 mg tablets Chorionic gonadotropin Initial report 02.09.2025 Other BREVACTID 5000 IU powder and solvent for solution for injection Oxycodone hydrochloride (Ph.Eur.) Change notification 02.09.2025 Other Oxycodone hydrochloride – 1 A Pharma 10 mg prolonged-release tablets Methylphenidate hydrochloride Change notification 02.09.2025 Other Methylphenidate AL 27 mg prolonged-release tablets Methylphenidate hydrochloride Change notification 02.09.2025 Other Methylphenidate AL 18 mg prolonged-release tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 02.09.2025 Other Atorvastatin PUREN 40 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 02.09.2025 Other Atorvastatin PUREN 10 mg film-coated tablets Urapidil Change notification 02.09.2025 Other Urapidil PUREN 90 mg prolonged-release capsules Nevirapine Change notification 02.09.2025 Other Nevirapine Aurobindo 400 mg prolonged-release tablets Risperidone Change notification 02.09.2025 Other Risperidone Aurobindo 1 mg film-coated tablets Risperidone Change notification 02.09.2025 Other Risperidone PUREN 1 mg film-coated tablets Pregabalin Change notification 02.09.2025 Other Pregabalin Aurobindo 25 mg hard capsules Rivastigmine hydrogen tartrate Change notification 02.09.2025 Production problem Rivastigmine Aurobindo 6 mg hard capsules Timolol maleate Initial report 01.09.2025 Production problem Tim-Ophtal 0.5% sine Trandolapril; verapamil hydrochloride Change notification 01.09.2025 Other Tarka 180 mg/2 mg modified-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.09.2025 Other Seroquel Prolong 50 mg prolonged-release tablets - 2025.09.01
Active ingredients AM designation Message type Date of last message Type of reason Epinephrine hydrochloride Suprarenin ampoules Change notification 29.08.2025 Production problem Norepinephrine hydrochloride/noradrenaline hydrochloride Arterenol 1 ml Change notification 29.08.2025 Production problem Isophane insulin suspension for injection (Ph.Eur.) Protaphane FlexPen 100 IU/ml injection suspension in injector – OP (10x3ml) Initial report 29.08.2025 Other Sodium (methylprednisolone-21-succinate) Urbason solubile forte 1000 mg Change notification 29.08.2025 Other Doxepin hydrochloride (Ph.Eur.) Doxepin 25 Holsten Change notification 29.08.2025 Production problem Olanzapine embonate monohydrate ZYPADHERA 405 mg powder and solvent for the preparation of a depot injection suspension – OP(931mg+3ml) Change notification 29.08.2025 Production problem Olanzapine embonate monohydrate ZYPADHERA 300 mg powder and solvent for the preparation of a prolonged-release injection suspension – OP(690mg+3ml) Change notification 29.08.2025 Production problem Terazosin hydrochloride dihydrate Tera TAD 2mg Change notification 28.08.2025 Other Terazosin hydrochloride dihydrate Tera TAD 5mg Change notification 28.08.2025 Other Terazosin hydrochloride dihydrate Tera TAD 10mg Change notification 28.08.2025 Other Oxcarbazepine Oxcarbazepine – 1 A Pharma 60 mg/ml oral suspension Initial report 28.08.2025 Other Quetiapine fumarate (Ph.Eur.) Quetiapine-Hormosan 200 mg prolonged-release tablets Change notification 28.08.2025 Other Quetiapine fumarate (Ph.Eur.) Quetiapine Hormosan 300 mg prolonged-release tablets Change notification 28.08.2025 Other Quetiapine fumarate (Ph.Eur.) Quetiapine-Hormosan 400 mg prolonged-release tablets Change notification 28.08.2025 Other Medium-chain triglycerides; omega-3 acid triglycerides (with information on origin and/or composition); refined soybean oil (Ph.Eur.) Lipidem Emulsion for infusion Initial report 28.08.2025 Production problem Quetiapine fumarate (Ph.Eur.) Seroquel Prolong 150 mg prolonged-release tablets Initial report 28.08.2025 Other Calcitriol Calcitriol KyraMed 0.25 micrograms Initial report 28.08.2025 Other Quetiapine fumarate (Ph.Eur.) Quetiapine – 1 A Pharma 600 mg prolonged-release tablets Change notification 28.08.2025 Production problem Quetiapine fumarate (Ph.Eur.) Quetiapine – 1 A Pharma 50 mg prolonged-release tablets Change notification 28.08.2025 Production problem Quetiapine fumarate (Ph.Eur.) Quetiapine – 1 A Pharma 400 mg prolonged-release tablets Change notification 28.08.2025 Production problem Quetiapine fumarate (Ph.Eur.) Quetiapine – 1 A Pharma 300 mg prolonged-release tablets Change notification 28.08.2025 Production problem Quetiapine fumarate (Ph.Eur.) Quetiapine – 1 A Pharma 200 mg prolonged-release tablets Change notification 28.08.2025 Production problem Quetiapine fumarate (Ph.Eur.) Quetiapine – 1 A Pharma 150 mg prolonged-release tablets Change notification 28.08.2025 Production problem Sevelamer Renagel 800 mg film-coated tablets – OP(1×180) Initial report 28.08.2025 Other Paliperidone palmitate Paliperidone AL 25 mg Depot injection suspension in a pre-filled syringe Change notification 28.08.2025 Other Paliperidone palmitate Paliperidone AL 150 mg depot injection suspension in a pre-filled syringe Change notification 28.08.2025 Other Duloxetine hydrochloride Duloxetine AL 120 mg gastro-resistant hard capsules Change notification 28.08.2025 Other Aprepitant Aprepitant STADA 80 mg hard capsules Change notification 28.08.2025 Production problem Methylphenidate hydrochloride Methylphenidate AL 18 mg prolonged-release tablets Change notification 28.08.2025 Other Ipratropium bromide (Ph.Eur.) Ipratropium Teva 250 micrograms/1 ml solution for nebulizer Change notification 28.08.2025 Production problem Oxazepam Oxa-CT 10 mg tablets Change notification 28.08.2025 Other Ribavirin Ribavirin-ratiopharm 200 mg film-coated tablets Change notification 28.08.2025 Other Ribavirin Ribavirin-ratiopharm 400 mg film-coated tablets Change notification 28.08.2025 Other Carbamazepine Carbamazepine-ratiopharm 200 mg prolonged-release tablets Change notification 28.08.2025 Other Oxazepam Oxazepam-ratiopharm 10 mg tablets Change notification 28.08.2025 Other Pramipexole dihydrochloride monohydrate Pramipexole-ratiopharm 0.52 mg prolonged-release tablets Change notification 28.08.2025 Other Rosuvastatin Hemicalcium Rosuvastatin Aristo 5 mg film-coated tablets Change notification 27.08.2025 Production problem Rosuvastatin Hemicalcium Rosuvastatin Aristo 20 mg film-coated tablets Change notification 27.08.2025 Other Rosuvastatin Hemicalcium Rosuvastatin Aristo 10 mg film-coated tablets Change notification 27.08.2025 Other Melperone hydrochloride Melperone Aristo 50 mg film-coated tablets Change notification 27.08.2025 Other Melperone hydrochloride Melperon Aristo 100 mg film-coated tablets Change notification 27.08.2025 Production problem Oxazepam Oxazepam AL 10 Change notification 27.08.2025 Other Atorvastatin calcium trihydrate (Ph.Eur.) Atorvastatin Aristo 60 mg film-coated tablets Change notification 27.08.2025 Other Codeine phosphate hemihydrate; caffeine; paracetamol Azur compositum Change notification 27.08.2025 Other Esomeprazole hemimagnesium ESOMEPRAZOLE BASICS 40 mg gastro-resistant hard capsules Change notification 27.08.2025 Production problem Esomeprazole hemimagnesium ESOMEPRAZOLE BASICS 20 mg gastro-resistant hard capsules Change notification 27.08.2025 Production problem Clarithromycin CLARITHROMYCIN BASICS 250 mg/5 ml granules for oral suspension Change notification 27.08.2025 Production problem Chlortalidone Chlortalidone HEXAL 50 mg tablets Change notification 27.08.2025 Other Chlortalidone Chlortalidone HEXAL 25 mg tablets Change notification 27.08.2025 Other Pramipexole dihydrochloride monohydrate Pramipexole Mylan 3.15 mg prolonged-release tablets Initial report 27.08.2025 Other Amikacin sulfate Amikacin B. Braun 5 mg/ml solution for infusion Initial report 27.08.2025 Production problem Amikacin sulfate Amikacin B. Braun 2.5 mg/ml solution for infusion Initial report 27.08.2025 Production problem Calcitriol Renatriol 0.25 µg Initial report 26.08.2025 Other Anastrozole Anastrozole Denk 1 mg film-coated tablets Initial report 26.08.2025 Other Clopidogrel besylate Clopidogrel Denk 75 mg film-coated tablets Change notification 26.08.2025 Other Ketotifen fumarate Ketotifen STADA 1 mg hard capsules Change notification 26.08.2025 Production problem Midodrine hydrochloride Gutron tablets Change notification 26.08.2025 Other Clomethiazole hemidisilate Distraneurin mixture Initial report 25.08.2025 Other Pramipexole dihydrochloride monohydrate Pramipexole – 1 A Pharma 0.26 mg prolonged-release tablets Change notification 25.08.2025 Other Sodium mycophenolate Mycophenolic acid HEXAL 360 mg gastro-resistant tablets Change notification 25.08.2025 Other Quetiapine fumarate (Ph.Eur.) Quetiapine HEXAL 50 mg prolonged-release tablets Change notification 25.08.2025 Production problem Quetiapine fumarate (Ph.Eur.) Quetiapine HEXAL 400 mg prolonged-release tablets Change notification 25.08.2025 Production problem Quetiapine fumarate (Ph.Eur.) Quetiapine HEXAL 300 mg prolonged-release tablets Change notification 25.08.2025 Production problem Quetiapine fumarate (Ph.Eur.) Quetiapine HEXAL 200 mg prolonged-release tablets Change notification 25.08.2025 Production problem Quetiapine fumarate (Ph.Eur.) Quetiapine HEXAL 150 mg prolonged-release tablets Change notification 25.08.2025 Production problem Methylphenidate hydrochloride Methylphenidate hydrochloride – 1 A Pharma 36 mg prolonged-release tablets Change notification 25.08.2025 Other Methylphenidate hydrochloride Methylphenidate hydrochloride HEXAL 36 mg prolonged-release tablets Change notification 25.08.2025 Other Insulin glargine Semglee 100 units/ml solution for injection in pre-filled pen – OP(5x3ml) Change notification 25.08.2025 Other Levetiracetam Levetiracetam – 1 A Pharma 1500 mg film-coated tablets Change notification 25.08.2025 Other
フランス
- 2025.09.28
Active ingredients Statut Update Specialty demeclocycline hydrochloride Out of stock 26/09/2025 Alkonatrem 150 mg, capsule lenalidomide Out of stock 26/09/2025 Lenalidomide Mylan, capsule methylphenidate hydrochloride Supply tension 24/09/2025 Methylphenidate Biogaran, extendedrelease tablet cyclophosphamide Supply tension 24/09/2025 Endoxan 50 mg, coated tablet adrenaline Supply tension 24/09/2025 Epipen, solution for injection in prefilled pen methotrexate Return to availability 23/09/2025 Viatris methotrexate 100 mg/ml, solution for injection (10 ml and 50 ml vials) tiapride (chlorhydrate de) Return to availability 23/09/2025 Tiapridal 100 mg/2 ml, solution injectable sertraline (hydrochloride) Return to availability 23/09/2025 Sertraline 25 mg and 50 mg, capsule sugammadex sodique Return to availability 23/09/2025 Sugammadex 100 mg/mL, solution injectable flacons de 5 ml Immunoglobulin normal human (IgG) Supply tension 22/09/2025 Immunoglobulin normal human IV and SC (based on) fluoroestradiol (18F) Return to availability 22/09/2025 Estrotep 500 MBq/mL, solution injectable potassium (bicarbonate) /potassium (citrate) Out of stock 22/09/2025 Sibnayal 8 mEq, sustainedrelease granules - 2025.09.22
Statut Update Specialty cyanocobalamin Supply tension 19/09/2025 Vitamin B12 Delagrange 1000 micrograms/2 mL, injectable (IM) and oral solution carmustine Return to availability 17/09/2025 Gliadel 7,7 mg, implant lenalidomide. Out of stock 17/09/2025 Lenalidomide Mylan, capsule alfacalcidol. Return to availability 16/09/2025 UnAlpha 1 microgram, oral capsules - 2025.09.15
Active ingredients Statut Update Specialty cyanocobalamine Supply tension 12/09/2025 Vitamine B12 Gerda 1000 µg/4 ml, solution injectable (IM) et buvable insulin aspart ((yeast/saccharomyces cerevisiae)) Supply tension 12/09/2025 Fiasp Flextouch 100 units/ml, solution for injection in prefilled pen methylphenidate hydrochloride Supply tension 11/09/2025 Methylphenidate Biogaran, extendedrelease tablet etoposide Return to availability 10/09/2025 Etoposide Teva, solution for infusion venlafaxine Supply tension 10/09/2025 Specialties based on Venlafaxine LP 37.5 mg and LP 75 mg sustainedrelease capsules sitagliptin Supply tension 10/09/2025 Specialties based on Sitagliptin 50 mg alglucosidase alfa ((mammalian/hamster/ cho cells)) Supply tension 09/09/2025 Myozyme 50 mg, powder for solution for diluted infusion Quinapril hydrochloride Discontinuation 09/09/2025 Acuitel 5 mg and 20 mg, scored coated tablet - 2025.09.08
Statut Update Specialty methylphenidate hydrochloride Return to availability 05/09/2025 Methylphenidate EG LP 18 mg, 36 mg and 54 mg, sustainedrelease tablet emtricitabine/tenofovir disoproxil Supply tension 05/09/2025 Speciality based on emtricitabine/tenofovir disoproxil 200 mg/245 mg, filmcoated tablet brimonidine Return to availability 03/09/2025 Specialties based on brimonidine 0.2% (2 mg/ml), eye drops solution lenalidomide Stock shortage 03/09/2025 Lenalidomide Mylan, capsule peginterferon alfa-2a Supply tension 02/09/2025 Pegasys 90 micrograms, 135 micrograms and 180 micrograms solution for injection in prefilled syringes carbamazepine Return to availability 02/09/2025 Tegretol L.P. 400 mg, extendedrelease scored filmcoated tablet alfacalcidol Supply tension 01/09/2025 UnAlfa 0.10 microgram, solution buvable en gouttes bosentan monohydrate Supply tension 01/09/2025 Bosentan Arrow 125 mg, scored filmcoated tablet bosentan monohydrate Return to availability 01/09/2025 Tracleer 125 mg, filmcoated tablet - 2025.09.01
Active ingredients Statut Update Specialty methylprednisolone (sodium hydrogen succinate) Supply tension 29/08/2025 Methylprednisolone Hikma 500 mg, powder for injectable solution dipyridamole Supply tension 29/08/2025 Persantine 10 mg/2 mL, solution injectable, ampoule VaricellaZoster Virus (VZV) glycoprotein E antigen (recombinant, adjuvanted) (mammalian/hamster/CHO cells) Supply tension 29/08/2025 Shingrix, powder and suspension for injectable suspension. Varicella zoster vaccine (recombinant, adjuvanted) fludarabine (phosphate) Return to availability 28/08/2025 Fludarabine Teva 25 mg/mL, diluent solution for injection/infusion atropine (sulfate) Supply tension 27/08/2025 Atropine 0.3%, eye drops methylphenidate hydrochloride Supply tension 27/08/2025 Concerta LP, extendedrelease tablet linezolid Return to availability 27/08/2025 Linezolid 2 mg/mL, solution for infusion venlafaxine Supply tension 27/08/2025 Specialties based on Venlafaxine LP 37.5 mg and LP 75 mg sustainedrelease capsules clomipramine (hydrochloride) Stock shortage 27/08/2025 Anafranil 25 mg, coated tablet cytarabine Supply tension 26/08/2025 Cytarabine Sandoz 100 mg/ml, solution for injection 1 glass bottle(s) of 50 ml glucagon (hydrochloride) Return to availability 26/08/2025 GlucaGen Kit 1 mg/ml, powder and solvent for solution for injection acetylcholine chloride Supply tension 26/08/2025 Miochole 20 mg, powder and solvent for intraocular solution sitagliptin Supply tension 26/08/2025 Specialties based on Sitagliptin 50 mg tobramycin Stock shortage 26/08/2025 Tobi Podhaler 28 mg, powder for inhalation capsule linezolid Return to availability 25/08/2025 Linezolid 600 mg, filmcoated tablet methylprednisolone (sodium hydrogen succinate) Supply tension 25/08/2025 Methylprednisolone Hikma 40 mg, powder for injectable solution
英国
- 2025.09.23
Medicine supply notification: Admelog® (insulin lispro)
Admelog® (insulin lispro) 100 units/ml solution for injection cartridges, pre-filled pens and vials are being discontinued with supplies anticipated to be exhausted by mid-March 2026, late March 2026 and mid-June 2026, respectively. Humalog® products can support increased demand.
Admelog®(インスリンリスプロ)は、注射カートリッジ、プレフィルドペン、バイアル用の100ユニット/ml溶液を製造中止しており、それぞれ2026年3月中旬、2026年3月下旬、2026年6月中旬までに供給がなくなる見込みです。Humalog®製品は、需要の増加に対応できます。
注：Admelogは、サノフィのバイオシミラー製剤。日本でも上市されている。
EU
EUの情報はありません。