更新された供給不足状況を示しています。
ある時点での供給不足の全体的状況は「供給関連情報」に定期的にアップします。
米国
- 2025.08.18
Generic Name Shortage Status Revision Date Created Date Imatinib Mesylate Tablets Current Shortages 15-Aug-25 14-May-25 Lidocaine with Epinephrine Injection Current Shortages 15-Aug-25 25-Jun-15 Liraglutide Injection Current Shortages 15-Aug-25 20-Jul-23 Minoxidil 2.5 mg Tablets Current Shortages 15-Aug-25 28-Nov-23 Ribavirin Inhalation Current Shortages 15-Aug-25 23-May-23 Cefdinir Oral Presentations Current Shortages 14-Aug-25 29-Jun-23 Dimenhydrinate Injection Current Shortages 14-Aug-25 14-Aug-25 Heparin Lock Flush Syringes Resolved Shortages 14-Aug-25 18-Dec-24 Lidocaine Injection Current Shortages 14-Aug-25 23-Jun-15 Lorazepam Tablets Current Shortages 14-Aug-25 4-Oct-18 Mometasone Furoate Aerosol for Oral Inhalation Current Shortages 14-Aug-25 29-Jul-25 Morphine Sulfate Extended-Release Tablets Current Shortages 14-Aug-25 12-Dec-24 Morphine Sulfate Immediate-Release Tablets Current Shortages 14-Aug-25 6-Apr-25 Acetaminophen Injection Current Shortages 13-Aug-25 12-Mar-25 Adenosine Injection Current Shortages 13-Aug-25 3-Apr-23 Dextran Low Molecular Weight (Dextran 40), 10% Injection Current Shortages 13-Aug-25 13-Aug-25 Pyridostigmine Bromide Extended-Release Tablets Current Shortages 13-Aug-25 7-Feb-25 Remifentanil Injection Current Shortages 13-Aug-25 22-Jun-22 Valproate Sodium Injection Current Shortages 13-Aug-25 13-Aug-25 Atropine Sulfate Injection Current Shortages 12-Aug-25 8-Jun-15 Dexmedetomidine Hydrochloride 100 mcg/mL Vials for Injection Current Shortages 12-Aug-25 3-Jul-24 Dexmedetomidine Hydrochloride 4 mcg/mL Premix for Injection Current Shortages 12-Aug-25 2-Jun-25 Leucovorin Calcium Injection Current Shortages 12-Aug-25 2-Jun-15 Lorazepam Injection Current Shortages 12-Aug-25 23-Jun-15 Mesna Injection Resolved Shortages 12-Aug-25 21-Feb-24 Metoprolol Injection Current Shortages 12-Aug-25 7-Nov-17 Metronidazole Hydrochloride Injection Current Shortages 12-Aug-25 20-Oct-21 Midazolam Injection Current Shortages 12-Aug-25 14-Jun-19 Morphine Injection Current Shortages 12-Aug-25 3-Jun-15 Nalbuphine Injection Current Shortages 12-Aug-25 8-Nov-22 Orphenadrine Citrate Injection Resolved Shortages 12-Aug-25 16-Jul-24 Phenytoin Sodium Injection Current Shortages 12-Aug-25 20-Dec-22 Propofol Emulsion Injection Current Shortages 12-Aug-25 2-Apr-20 Sodium Bicarbonate Injection Current Shortages 12-Aug-25 17-Feb-17 - 2025.08.18
New
August 15, 2025
- Celecoxib Capsule (Discontinuation)
August 13, 2025
- Palivizumab Injection (Discontinuation)
August 12, 2025
- Desipramine Hydrochloride Tablet (Discontinuation)
Updated
August 15, 2025
- Cromolyn Sodium Concentrate (Currently In Shortage)
August 11, 2025
- Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Currently In Shortage)
- Dexamethasone Sodium Phosphate Injection (Currently In Shortage)
- Dextrose Monohydrate 10% Injection (Currently In Shortage)
- Fentanyl Citrate Injection (Currently In Shortage)
- Hydromorphone Hydrochloride Injection (Currently In Shortage)
- Morphine Sulfate Injection (Currently In Shortage)
- Rocuronium Bromide Injection (Currently In Shortage)
- Sodium Bicarbonate Injection (Currently In Shortage)
- 2025.08.11
Generic Name Shortage Status Revision Date Created Date Alteplase Injection Current Shortages 9-Aug-25 22-Nov-24 Amphetamine Mixed Salts, Immediate-Release Tablets Current Shortages 9-Aug-25 27-Jul-22 Difluprednate Ophthalmic Emulsion Current Shortages 9-Aug-25 17-Apr-24 Dihydroergotamine Mesylate Injection Current Shortages 9-Aug-25 8-Aug-24 Epinephrine Auto-Injectors Current Shortages 9-Aug-25 3-May-18 Heparin Injection Current Shortages 9-Aug-25 12-Oct-17 Peginterferon Alfa-2a Injection Current Shortages 9-Aug-25 8-Jan-25 Bupivacaine Injection Current Shortages 8-Aug-25 14-Sep-15 Conjugated Estrogens Injection Current Shortages 8-Aug-25 21-May-25 Lanthanum Carbonate Oral Presentations Current Shortages 8-Aug-25 2-Apr-25 Methylphenidate Extended Release Oral Presentations Current Shortages 8-Aug-25 15-Dec-22 Oxycodone Hydrochloride and Acetaminophen Tablets Current Shortages 8-Aug-25 19-Jul-23 Oxycodone Hydrochloride Immediate-Release Tablets Current Shortages 8-Aug-25 16-Mar-23 Amphetamine Extended-Release Oral Presentations Current Shortages 7-Aug-25 22-Aug-22 Capecitabine Tablets Current Shortages 7-Aug-25 1-Feb-23 Dexmethylphenidate Extended Release Capsules Current Shortages 7-Aug-25 26-May-23 Dextroamphetamine Extended-Release Capsules Current Shortages 7-Aug-25 16-Jul-25 Meperidine Hydrochloride Injection Current Shortages 7-Aug-25 20-Mar-24 Methylprednisolone Sodium Succinate Injection Current Shortages 7-Aug-25 23-Mar-23 Remifentanil Injection Current Shortages 7-Aug-25 22-Jun-22 0.9% Sodium Chloride Large Volume Bags Resolved Shortages 6-Aug-25 4-Oct-24 50% Dextrose Injection Current Shortages 6-Aug-25 12-Dec-21 Amino Acid Products Current Shortages 6-Aug-25 15-May-19 Antivenin Latrodectus Mactans (Black Widow Spider Antivenin) Current Shortages 6-Aug-25 11-Jun-15 Cefdinir Oral Presentations Current Shortages 6-Aug-25 29-Jun-23 Clonazepam Oral Tablets Current Shortages 6-Aug-25 10-Apr-23 Dextran Low Molecular Weight (Dextran 40), 10% Injection Resolved Shortages 6-Aug-25 30-Oct-24 Diazepam Injection Current Shortages 6-Aug-25 11-Jan-24 Diltiazem Hydrochloride Injection Current Shortages 6-Aug-25 29-Jan-25 Dobutamine Injection Current Shortages 6-Aug-25 1-Mar-17 Dopamine Hydrochloride Injection Current Shortages 6-Aug-25 9-Mar-22 Erythromycin Lactobionate Injection Current Shortages 6-Aug-25 21-Apr-25 Fentanyl Citrate Injection Current Shortages 6-Aug-25 8-May-17 Furosemide Injection Current Shortages 6-Aug-25 18-May-17 Hydrocortisone Sodium Succinate Injection Current Shortages 6-Aug-25 1-Mar-23 Insulin Degludec Injection Resolved Shortages 6-Aug-25 13-Mar-25 Insulin Glargine Injection (Recombinant) Current Shortages 6-Aug-25 19-Feb-25 Mannitol Injection Current Shortages 6-Aug-25 9-Oct-24 Mercaptopurine Tablets Current Shortages 6-Aug-25 8-Jan-24 Mitomycin Injection Current Shortages 6-Aug-25 3-Mar-23 Oxymorphone Immediate-Release Tablets Resolved Shortages 6-Aug-25 24-Oct-23 Potassium Chloride Injection Current Shortages 6-Aug-25 3-Nov-24 Acetaminophen Injection Current Shortages 5-Aug-25 12-Mar-25 Acetylcysteine Oral and Inhalation Solution Current Shortages 5-Aug-25 8-Jun-15 Adenosine Injection Current Shortages 5-Aug-25 3-Apr-23 Amiodarone Injection Current Shortages 5-Aug-25 6-Jan-18 Chlorothiazide Sodium Injection Current Shortages 5-Aug-25 12-Mar-25 Cisplatin Injection Current Shortages 5-Aug-25 10-Jan-23 Clindamycin Phosphate Injection Current Shortages 5-Aug-25 25-Jun-15 Sufentanil Injection Resolved Shortages 5-Aug-25 15-Apr-25 Triamcinolone Acetonide Injectable Suspension Current Shortages 5-Aug-25 2-Jun-25 Fluocinolone Acetonide Intravitreal Implant Current Shortages 4-Aug-25 4-Aug-25 Lanreotide Acetate Injection Current Shortages 4-Aug-25 9-Oct-24 Lenalidomide Capsules Current Shortages 4-Aug-25 11-Jan-24 Naltrexone Tablets Current Shortages 4-Aug-25 7-Feb-24 Penicillin V Potassium Oral Presentations Current Shortages 4-Aug-25 17-May-23 - 2025.08.11
New
August 8, 2025
- Amphotericin B Injection (Discontinuation)
Updated
August 8, 2025
- Bupivacaine Hydrochloride Injection (Currently In Shortage)
- Dexamethasone Sodium Phosphate Injection (Currently In Shortage)
- Heparin Sodium Injection (Currently In Shortage)
- Lidocaine Hydrochloride Injection (Currently In Shortage)
- Methylprednisolone Acetate Injection (Currently In Shortage)
- Rocuronium Bromide Injection (Currently In Shortage)
- Ropivacaine Hydrochloride Injection (Currently In Shortage)
- Sodium Chloride 0.9% Injection (Resolved)
- 2025.08.04
- 2025.08.04
New
August 1, 2025
- Clindamycin Phosphate; Benzoyl Peroxide Gel (Discontinuation)
July 29, 2025
- Adefovir Dipivoxil Tablet (Discontinuation)
- Esterified Estrogens Tablet (Discontinuation)
July 28, 2025
- Voriconazole Tablet (Discontinuation)
Updated
August 1, 2025
- Indocyanine Green Injection (Currently In Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently In Shortage)
- Methamphetamine Hydrochloride Tablet (Currently In Shortage)
July 31, 2025
- Bupivacaine Hydrochloride Injection (Currently In Shortage)
- Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Currently In Shortage)
- Clindamycin Phosphate Injection (Currently In Shortage)
- Dobutamine Hydrochloride Injection (Currently In Shortage)
- Dopamine Hydrochloride Injection (Currently In Shortage)
- Furosemide Injection (Currently In Shortage)
- Hydrocortisone Sodium Succinate Injection (Currently In Shortage)
- Hydromorphone Hydrochloride Injection (Currently In Shortage)
- Lidocaine Hydrochloride Injection (Currently In Shortage)
- Lorazepam Injection (Currently In Shortage)
- Meperidine Hydrochloride Injection (Currently In Shortage)
- Methotrexate Sodium Injection (Currently In Shortage)
- Methylprednisolone Acetate Injection (Currently In Shortage)
- Midazolam Hydrochloride Injection (Currently In Shortage)
- Morphine Sulfate Injection (Currently In Shortage)
- Penicillin G Benzathine Injection (Currently In Shortage)
- Sodium Bicarbonate Injection (Currently In Shortage)
- Sodium Chloride 0.9% Injection (Currently In Shortage)
- Sterile Water Injection (Currently In Shortage)
- Sufentanil Citrate Injection (Currently In Shortage)
July 28, 2025
- Carboplatin Injection (Currently In Shortage)
カナダ
カナダの情報はありません。
オーストラリア
- 2025.08.18
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated naproxen Tablet, modified release 750 mg Anticipated Available Manufacturing 15/08/2025 Measles virus~Rubella virus~live varicella vaccine~Mumps virus Injection, powder for 1000 CCID50~1000 CCID50~1995 PFU~25119 CCID50 Current Limited Availability Manufacturing 15/08/2025 propofol Injection, emulsion 1000 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 15/08/2025 aripiprazole Tablet, uncoated 30 mg Current Limited Availability Manufacturing 15/08/2025 bisoprolol fumarate Tablet 2.5 mg Anticipated Available Manufacturing 15/08/2025 bisoprolol fumarate Tablet 5 mg Anticipated Available Manufacturing 15/08/2025 bisoprolol fumarate Tablet 10 mg Anticipated Available Manufacturing 15/08/2025 ondansetron hydrochloride dihydrate Tablet, film coated 9.972 mg Current Limited Availability Manufacturing 15/08/2025 indapamide hemihydrate Tablet, sugar coated 2.5 mg Anticipated Available Manufacturing 15/08/2025 milrinone Injection, concentrated 10 mg Current Limited Availability Manufacturing 15/08/2025 clopidogrel besilate Tablet, film coated 112.1 mg Current Unavailable Manufacturing 15/08/2025 Pneumococcal purified capsular polysaccharides Injection, solution 50 microgram/mL Resolved Available Unexpected increase in consumer demand 15/08/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Limited Availability Unexpected increase in consumer demand 15/08/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Unexpected increase in consumer demand 15/08/2025 live varicella vaccine Injection, powder for 4000 PFU/mL Resolved Available Unexpected increase in demand due to other sponsors unable to supply 15/08/2025 nizatidine Capsule, hard 150 mg Current Unavailable Manufacturing 15/08/2025 sildenafil citrate Tablet, film coated 140.48 mg Current Limited Availability Manufacturing 15/08/2025 sildenafil citrate Tablet, film coated 70.24 mg Current Unavailable Unexpected increase in consumer demand 15/08/2025 sildenafil citrate Tablet, film coated 140.48 mg Current Limited Availability Manufacturing 15/08/2025 melatonin Capsule, hard 2 mg Resolved Available Unexpected increase in consumer demand 15/08/2025 reboxetine mesilate Tablet, uncoated 5.224 mg Resolved Available Manufacturing 15/08/2025 propofol Injection, emulsion 500 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 14/08/2025 risperidone Tablet, film coated 1 mg Anticipated Available Manufacturing 14/08/2025 propofol Injection, emulsion 500 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 14/08/2025 mycophenolate mofetil Capsule 250 mg Current Unavailable Manufacturing 14/08/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Manufacturing 14/08/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Current Unavailable Manufacturing 14/08/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 14/08/2025 ondansetron Tablet, orally disintegrating 8 mg Resolved Available Manufacturing 14/08/2025 atorvastatin calcium trihydrate~amlodipine besilate Tablet, film coated 43.376 mg~13.88 mg Anticipated Available Manufacturing 14/08/2025 docetaxel Injection, concentrated 80 mg Anticipated Available Manufacturing 14/08/2025 carboplatin Injection, solution 450 mg Anticipated Available Manufacturing 14/08/2025 citalopram hydrobromide Tablet, film coated 49.98 mg Current Limited Availability Manufacturing 14/08/2025 bimatoprost Eye Drops .3 mg/mL Current Unavailable Manufacturing 14/08/2025 linezolid Tablet, film coated 600 mg Current Unavailable Manufacturing 14/08/2025 ezetimibe Tablet, uncoated 10 mg Current Limited Availability Unexpected increase in consumer demand 14/08/2025 azacitidine Injection, powder for 100 mg Current Unavailable Manufacturing 14/08/2025 irbesartan Tablet, film coated 75 mg Anticipated Available Manufacturing 14/08/2025 tadalafil Tablet, film coated 10 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 14/08/2025 nizatidine Capsule, hard 150 mg Current Unavailable Manufacturing 14/08/2025 ivabradine hydrochloride Tablet, film coated 5.39 mg Current Unavailable Manufacturing 14/08/2025 mebeverine hydrochloride Tablet, film coated 135 mg Current Limited Availability Manufacturing 14/08/2025 metformin hydrochloride Tablet, film coated 1000 mg Resolved Available Manufacturing 14/08/2025 paclitaxel Injection, powder for 100 mg Current Unavailable Manufacturing 14/08/2025 pomalidomide Capsule, hard 2 mg Resolved Available Manufacturing 14/08/2025 avatrombopag maleate Tablet, film coated 23.6 mg Resolved Available Manufacturing 14/08/2025 levothyroxine sodium Tablet 100 microgram Current Unavailable Unexpected increase in consumer demand 14/08/2025 metformin hydrochloride~sitagliptin hydrochloride monohydrate Tablet, film coated 500 mg~56.69 mg Current Unavailable Manufacturing 14/08/2025 sitagliptin hydrochloride monohydrate~metformin hydrochloride Tablet, film coated 56.69 mg~850 mg Current Unavailable Manufacturing 14/08/2025 sirolimus Oral Liquid, solution 1 mg/mL Resolved Available Manufacturing 14/08/2025 ciprofloxacin hydrochloride Tablet, film coated 873.32 mg Anticipated Available Manufacturing 14/08/2025 Somatropin Injection, powder for 12 mg/mL Anticipated Available Unexpected increase in consumer demand 13/08/2025 acetylcysteine Injection, concentrated 2 g Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 13/08/2025 bosentan monohydrate Tablet, film coated 129.082 mg Resolved Available Manufacturing 13/08/2025 tobramycin Eye Ointment 3 mg/g Resolved Available Manufacturing 13/08/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Resolved Available Manufacturing 13/08/2025 levodopa~carbidopa monohydrate Tablet, uncoated 100 mg~27 mg Anticipated Available Manufacturing 13/08/2025 flucloxacillin sodium monohydrate Injection, powder for 544.1 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 13/08/2025 lanreotide acetate Injection, solution 133.33 mg Resolved Available Manufacturing 13/08/2025 cefalexin monohydrate Capsule, hard 275 mg Resolved Available Manufacturing 13/08/2025 propofol Injection, emulsion 10 mg/mL Resolved Available Manufacturing 13/08/2025 terbinafine hydrochloride Tablet, uncoated 281.25 mg Anticipated Available Manufacturing 12/08/2025 prazosin hydrochloride Tablet, uncoated 1.095 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 12/08/2025 prazosin hydrochloride Tablet, uncoated 5.476 mg Anticipated Available Unexpected increase in consumer demand 12/08/2025 acetylcholine chloride Solution, powder for irrigation 10 mg/mL Current Unavailable Manufacturing 12/08/2025 tetrabenazine Tablet, uncoated 25 mg Anticipated Available Manufacturing 12/08/2025 ondansetron hydrochloride dihydrate Injection, solution 5 mg Current Limited Availability Manufacturing 12/08/2025 propranolol hydrochloride Tablet, film coated 40 mg Current Unavailable Manufacturing 12/08/2025 trimethoprim~sulfamethoxazole Tablet, uncoated 160 mg~800 mg Current Limited Availability Manufacturing 12/08/2025 ezetimibe~atorvastatin calcium trihydrate Tablet, multilayer 10 mg~10.9 mg Anticipated Available Manufacturing 12/08/2025 Infliximab Injection, powder for 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 12/08/2025 methylphenidate hydrochloride Capsule, modified release 60 mg Current Unavailable Manufacturing 12/08/2025 solifenacin succinate Tablet, film coated 5 mg Current Unavailable Manufacturing 12/08/2025 ezetimibe~simvastatin Tablet 10 mg~40 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 12/08/2025 spironolactone Tablet, uncoated 100 mg Current Limited Availability Manufacturing 12/08/2025 Teriparatide Injection, solution .25 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 12/08/2025 levothyroxine sodium Tablet 75 microgram Current Unavailable Manufacturing 12/08/2025 lorazepam Tablet 1 mg Current Limited Availability Manufacturing 12/08/2025 Teriparatide Injection, solution 250 microgram/mL Current Limited Availability Manufacturing 12/08/2025 albendazole Tablet, chewable 400 mg Resolved Available Manufacturing 12/08/2025 fampridine Tablet, modified release 10 mg Anticipated Available Transport / Logistic issues / Storage capacity issues 11/08/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 11/08/2025 ciprofloxacin hydrochloride Tablet, film coated 277.5 mg Current Unavailable Manufacturing 11/08/2025 ciprofloxacin hydrochloride Tablet, film coated 555 mg Current Unavailable Manufacturing 11/08/2025 ciprofloxacin hydrochloride Tablet, film coated 832.5 mg Current Unavailable Manufacturing 11/08/2025 metoprolol succinate Tablet, modified release 95 mg Current Unavailable Manufacturing 11/08/2025 metoprolol succinate Tablet, modified release 47.5 mg Current Unavailable Manufacturing 11/08/2025 metoprolol succinate Tablet, modified release 190 mg Current Unavailable Manufacturing 11/08/2025 metoprolol succinate Tablet, modified release 23.75 mg Current Unavailable Manufacturing 11/08/2025 entecavir Tablet, film coated .5 mg Current Unavailable Manufacturing 11/08/2025 esomeprazole Capsule, enteric 20 mg Resolved Available Manufacturing 11/08/2025 celecoxib Capsule, hard 100 mg Current Unavailable Manufacturing 11/08/2025 alprazolam Tablet, uncoated 2 mg Resolved Available Manufacturing 11/08/2025 rifampicin Capsule, hard 300 mg Current Limited Availability Manufacturing 11/08/2025 - 2025.08.11
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated nortriptyline Tablet, film coated 10 mg Anticipated Available Manufacturing 8/08/2025 midazolam Injection, solution 15 mg Current Limited Availability Manufacturing 8/08/2025 midazolam Injection, solution 50 mg Current Limited Availability Manufacturing 8/08/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.9 mg Current Limited Availability Unexpected increase in consumer demand 8/08/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 8/08/2025 levodopa~entacapone~carbidopa monohydrate Tablet, film coated 75 mg~200 mg~20.25 mg Current Limited Availability Manufacturing 8/08/2025 quetiapine fumarate Tablet, modified release 460.52 mg Resolved Available Manufacturing 8/08/2025 ivermectin Cream 10 mg/g Resolved Available Manufacturing 8/08/2025 adrenaline (epinephrine) acid tartrate~articaine hydrochloride Injection, solution 18.2 microgram/mL~40 mg/mL Anticipated Available Transport / Logistic issues / Storage capacity issues 8/08/2025 tobramycin Eye Ointment 3 mg/g Anticipated Available Manufacturing 8/08/2025 phenytoin sodium Capsule, hard 30 mg Anticipated Available Manufacturing 8/08/2025 nitrofurantoin Capsule, hard 100 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 8/08/2025 bortezomib Injection, solution 3.5 mg Current Unavailable Manufacturing 8/08/2025 hydralazine hydrochloride Injection, powder for 20 mg Current Unavailable Manufacturing 8/08/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 8/08/2025 methylphenidate hydrochloride Tablet, uncoated 10 mg Anticipated Available Manufacturing 7/08/2025 lamotrigine Tablet, chewable 200 mg Anticipated Available Manufacturing 7/08/2025 metformin hydrochloride Tablet, film coated 500 mg Current Unavailable Manufacturing 7/08/2025 Pancreatic extract Capsule, enteric 300 mg Anticipated Available Unexpected increase in consumer demand 7/08/2025 methylphenidate hydrochloride Capsule, modified release 10 mg Current Limited Availability Manufacturing 7/08/2025 Choriogonadotropin alfa Injection, solution 250 microgram Current Limited Availability Unexpected increase in consumer demand 7/08/2025 indapamide hemihydrate Tablet, sugar coated 2.5 mg Anticipated Available Manufacturing 7/08/2025 metformin hydrochloride Tablet, film coated 1000 mg Current Unavailable Manufacturing 7/08/2025 oxytocin Injection, solution 5 IU/mL Current Limited Availability Unexpected increase in consumer demand 7/08/2025 capecitabine Tablet, film coated 500 mg Current Limited Availability Unexpected increase in consumer demand 7/08/2025 lansoprazole Tablet, orally disintegrating 15 mg Anticipated Available Manufacturing 7/08/2025 pramipexole dihydrochloride monohydrate Tablet, modified release .75 mg Anticipated Available Manufacturing 7/08/2025 pramipexole dihydrochloride monohydrate Tablet, modified release 1.5 mg Anticipated Available Manufacturing 7/08/2025 pramipexole dihydrochloride monohydrate Tablet, modified release 2.25 mg Current Limited Availability Manufacturing 7/08/2025 methylphenidate hydrochloride Capsule, modified release 60 mg Current Limited Availability Manufacturing 7/08/2025 atomoxetine hydrochloride Capsule, hard 45.72 mg Current Unavailable Manufacturing 7/08/2025 metformin hydrochloride Tablet, film coated 1000 mg Current Unavailable Unexpected increase in consumer demand 7/08/2025 lacosamide Tablet, film coated 50 mg Anticipated Available Manufacturing 7/08/2025 Pancreatic extract Capsule 420 mg Anticipated Available Unexpected increase in consumer demand 7/08/2025 midazolam maleate Solution 10.2 mg Current Limited Availability Manufacturing 7/08/2025 lanreotide acetate Injection, solution 133.33 mg Current Unavailable Manufacturing 7/08/2025 levothyroxine sodium Tablet 100 microgram Current Unavailable Unexpected increase in consumer demand 7/08/2025 Teriparatide Injection, solution 250 microgram/mL Anticipated Available Manufacturing 7/08/2025 methylphenidate hydrochloride Capsule, modified release 20 mg Current Limited Availability Manufacturing 7/08/2025 methylphenidate hydrochloride Capsule, modified release 40 mg Current Limited Availability Manufacturing 7/08/2025 flecainide acetate Injection, solution 10 mg/mL Current Unavailable Manufacturing 6/08/2025 metformin hydrochloride Tablet, film coated 850 mg Current Unavailable Manufacturing 6/08/2025 brimonidine tartrate Eye Drops, solution 1.5 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 6/08/2025 letrozole Tablet, film coated 2.5 mg Current Limited Availability Manufacturing 6/08/2025 phenobarbital sodium Injection, solution 219 mg/mL Resolved Available Manufacturing 6/08/2025 sumatriptan succinate Tablet, film coated 139.98 mg Resolved Available Manufacturing 6/08/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Limited Availability Manufacturing 6/08/2025 hydromorphone hydrochloride Injection, solution 2 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 6/08/2025 cinacalcet hydrochloride Tablet, film coated 99 mg Resolved Available Manufacturing 6/08/2025 lurasidone hydrochloride Tablet, film coated 80 mg Current Unavailable Manufacturing 6/08/2025 methylphenidate hydrochloride Capsule, hard 40 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 6/08/2025 methylphenidate hydrochloride Capsule, hard 10 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 6/08/2025 methylphenidate hydrochloride Capsule, hard 60 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 6/08/2025 sirolimus Oral Liquid, solution 1 mg/mL Current Limited Availability Manufacturing 6/08/2025 lorazepam Tablet, uncoated 1 mg Resolved Available Manufacturing 5/08/2025 phenoxymethylpenicillin potassium Oral Liquid, powder for 28.284 mg/mL Anticipated Available Manufacturing 5/08/2025 olanzapine Tablet, orally disintegrating 5 mg Resolved Available Manufacturing 5/08/2025 amoxicillin trihydrate Capsule, hard 286.95 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 5/08/2025 encorafenib Capsule, hard 50 mg Current Unavailable Manufacturing 5/08/2025 daptomycin Injection, powder for 350 mg Current Limited Availability Manufacturing 5/08/2025 montelukast sodium Tablet, chewable 5.2 mg Current Unavailable Manufacturing 5/08/2025 deferasirox Tablet, film coated 360 mg Current Limited Availability Manufacturing 5/08/2025 methylphenidate hydrochloride Capsule, hard 30 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 5/08/2025 levothyroxine sodium Tablet 200 microgram Current Unavailable Unexpected increase in consumer demand 5/08/2025 melatonin Capsule, hard 2 mg Current Unavailable Unexpected increase in consumer demand 5/08/2025 mirtazapine Tablet, film coated 30 mg Current Limited Availability Manufacturing 5/08/2025 propofol Injection, emulsion 200 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 4/08/2025 phenoxymethylpenicillin potassium Tablet, film coated 560 mg Anticipated Available Manufacturing 4/08/2025 atorvastatin calcium trihydrate~ezetimibe Tablet, film coated 82.725 mg~10 mg Resolved Available Manufacturing 4/08/2025 naloxone hydrochloride dihydrate Injection 440 microgram Current Unavailable Unexpected increase in consumer demand 4/08/2025 levothyroxine sodium Tablet, uncoated .1 mg Resolved Available Manufacturing 4/08/2025 enoxaparin sodium Injection, solution 60 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 4/08/2025 flecainide acetate Tablet, uncoated 100 mg Resolved Available Manufacturing 4/08/2025 metformin hydrochloride Tablet, film coated 850 mg Resolved Available Manufacturing 4/08/2025 pioglitazone hydrochloride Tablet, uncoated 49.59 mg Current Unavailable Commercial Changes / Commercial viability 4/08/2025 - 2025.08.04
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated metformin hydrochloride Tablet, film coated 500 mg Current Unavailable Manufacturing 1/08/2025 prilocaine~lidocaine Gel 42.5 mg~42.5 mg Resolved Available Transport / Logistic issues / Storage capacity issues 1/08/2025 temozolomide Capsule, hard 5 mg Anticipated Available Manufacturing 1/08/2025 isotretinoin Capsule, soft 10 mg Current Unavailable Manufacturing 1/08/2025 isotretinoin Capsule, soft 20 mg Current Limited Availability Manufacturing 1/08/2025 entacapone~levodopa~carbidopa monohydrate Tablet, film coated 200 mg~200 mg~54 mg Current Unavailable Manufacturing 1/08/2025 quetiapine fumarate Tablet, modified release 172.695 mg Anticipated Available Manufacturing 1/08/2025 milrinone Injection, concentrated 10 mg Current Limited Availability Manufacturing 1/08/2025 salmeterol xinafoate~fluticasone propionate Inhalation, powder for 72.5 microgram/actuation~250 microgram/actuation Anticipated Available Unexpected increase in consumer demand 1/08/2025 Follitropin alfa Injection, solution 150 IU Resolved Available Manufacturing 1/08/2025 isotretinoin Capsule, soft 10 mg Current Limited Availability Manufacturing 1/08/2025 nicorandil Tablet, uncoated 10 mg Current Limited Availability Manufacturing 1/08/2025 tobramycin Inhalation, conventional 300 mg Discontinued Reduction in supply until supply is exhausted Manufacturing 1/08/2025 atorvastatin calcium trihydrate Tablet, film coated 86.751 mg Resolved Available Manufacturing 1/08/2025 omeprazole Capsule 20 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 1/08/2025 Peginterferon alfa2a Injection, solution 135 microgram Current Unavailable Unexpected increase in consumer demand 1/08/2025 Peginterferon alfa2a Injection, solution 180 microgram Current Unavailable Unexpected increase in consumer demand 1/08/2025 terbinafine hydrochloride Tablet, uncoated 281.25 mg Anticipated Available Manufacturing 31/07/2025 tramadol hydrochloride Capsule 50 mg Current Limited Availability Manufacturing 31/07/2025 indapamide hemihydrate Tablet, modified release 1.5 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 31/07/2025 letrozole Tablet, film coated 2.5 mg Current Limited Availability Manufacturing 31/07/2025 pioglitazone hydrochloride Tablet 16.63 mg Current Limited Availability Manufacturing 31/07/2025 exemestane Tablet, film coated 25 mg Resolved Available Manufacturing 31/07/2025 olanzapine Tablet, orally disintegrating 5 mg Current Unavailable Manufacturing 31/07/2025 trimethoprim~sulfamethoxazole Tablet, uncoated 160 mg~800 mg Anticipated Available Manufacturing 31/07/2025 levodopa~carbidopa monohydrate~entacapone Tablet, film coated 100 mg~27 mg~200 mg Current Unavailable Manufacturing 31/07/2025 carbidopa monohydrate~entacapone~levodopa Tablet, film coated 33.75 mg~200 mg~125 mg Current Limited Availability Manufacturing 31/07/2025 carbidopa monohydrate~levodopa~entacapone Tablet, film coated 40.5 mg~150 mg~200 mg Current Unavailable Manufacturing 31/07/2025 trandolapril Capsule, hard 1 mg Current Unavailable Manufacturing 31/07/2025 trandolapril Capsule, hard 2 mg Current Unavailable Manufacturing 31/07/2025 trandolapril Capsule, hard 4 mg Current Unavailable Manufacturing 31/07/2025 bosentan monohydrate Tablet, film coated 129.082 mg Current Unavailable Manufacturing 31/07/2025 entecavir Tablet, film coated .5 mg Current Unavailable Manufacturing 31/07/2025 esomeprazole Capsule, enteric 20 mg Current Unavailable Manufacturing 31/07/2025 ezetimibe Tablet, uncoated 10 mg Current Unavailable Unexpected increase in consumer demand 31/07/2025 ezetimibe Tablet, uncoated 10 mg Anticipated Available Unexpected increase in consumer demand 31/07/2025 emtricitabine~tenofovir disoproxil maleate Tablet, film coated 200 mg~300 mg Resolved Available Manufacturing 31/07/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Current Limited Availability Manufacturing 31/07/2025 mebeverine hydrochloride Tablet, film coated 135 mg Current Limited Availability Manufacturing 31/07/2025 encorafenib Capsule, hard 50 mg Current Limited Availability Manufacturing 31/07/2025 atorvastatin calcium trihydrate Tablet, film coated 86.751 mg Resolved Available Manufacturing 31/07/2025 chloramphenicol Eye Drops, solution 5 mg/mL Resolved Available Manufacturing 31/07/2025 lanreotide acetate Injection, solution 133.33 mg Current Unavailable Manufacturing 31/07/2025 levothyroxine sodium Tablet 75 microgram Current Unavailable Manufacturing 31/07/2025 trandolapril Capsule, hard 2 mg Current Unavailable Manufacturing 31/07/2025 risperidone Tablet, film coated 1 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 31/07/2025 risperidone Tablet, film coated 3 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 31/07/2025 risperidone Tablet, film coated 4 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 31/07/2025 risperidone Tablet, film coated 2 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 31/07/2025 imipramine hydrochloride Tablet, sugar coated 25 mg Current Unavailable Manufacturing 31/07/2025 risperidone Tablet, film coated .5 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 31/07/2025 citalopram hydrobromide Tablet, film coated 49.96 mg Current Unavailable Manufacturing 31/07/2025 nizatidine Capsule 150 mg Current Limited Availability Manufacturing 31/07/2025 phenobarbital sodium Injection, solution 219 mg/mL Current Unavailable Manufacturing 30/07/2025 sumatriptan succinate Tablet, film coated 139.98 mg Current Unavailable Manufacturing 30/07/2025 bazedoxifene acetate~conjugated estrogens Tablet, modified release 22.56 mg~.45 mg Current Unavailable Commercial Changes / Commercial viability 30/07/2025 azacitidine Injection, powder for 100 mg Current Unavailable Manufacturing 30/07/2025 cidofovir Injection, concentrated 75 mg/mL Anticipated Available Manufacturing 30/07/2025 neratinib maleate Tablet, film coated 48.31 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 30/07/2025 ceftazidime pentahydrate~avibactam sodium Injection, powder for 2329.7 mg~543.5 mg Resolved Available Unexpected increase in consumer demand 30/07/2025 teriflunomide Tablet, film coated 14 mg Current Limited Availability Manufacturing 30/07/2025 Trastuzumab Injection, powder for 60 mg Current Unavailable Manufacturing 30/07/2025 Trastuzumab Injection, powder for 150 mg Current Unavailable Manufacturing 30/07/2025 letrozole Tablet, film coated 2.5 mg Anticipated Available Manufacturing 30/07/2025 erlotinib hydrochloride Tablet, film coated 27.32 mg Current Unavailable Unexpected increase in consumer demand 30/07/2025 flucloxacillin sodium monohydrate Injection, powder for 544.1 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 30/07/2025 pomalidomide Capsule, hard 2 mg Current Unavailable Manufacturing 30/07/2025 bortezomib Injection, solution 3.5 mg Current Unavailable Manufacturing 30/07/2025 nitrofurantoin Capsule, hard 100 mg Anticipated Available Manufacturing 30/07/2025 levothyroxine sodium Tablet 200 microgram Current Unavailable Unexpected increase in consumer demand 30/07/2025 glyceryl trinitrate Drug delivery system, transdermal 54 mg Discontinued Unavailable Commercial Changes / Commercial viability 30/07/2025 labetalol hydrochloride Tablet, film coated 100 mg Current Limited Availability Manufacturing 30/07/2025 flecainide acetate Tablet, uncoated 100 mg Current Unavailable Manufacturing 30/07/2025 metformin hydrochloride Tablet, film coated 850 mg Current Unavailable Manufacturing 30/07/2025 albendazole Tablet, chewable 400 mg Current Unavailable Manufacturing 30/07/2025 ramipril Tablet, uncoated 1.25 mg Anticipated Available Manufacturing 29/07/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Emergency Supply Only Unexpected increase in demand due to other sponsors unable to supply 29/07/2025 bicalutamide Tablet, film coated 50 mg Resolved Available Unexpected increase in consumer demand 29/07/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.9 mg Current Limited Availability Unexpected increase in consumer demand 29/07/2025 acetylcysteine Injection, concentrated 2 g Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 29/07/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Current Limited Availability Manufacturing 29/07/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in consumer demand 29/07/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 29/07/2025 ezetimibe~simvastatin Tablet 10 mg~10 mg Current Limited Availability Manufacturing 29/07/2025 ezetimibe~simvastatin Tablet 10 mg~20 mg Current Limited Availability Manufacturing 29/07/2025 clopidogrel besilate Tablet, film coated 112.1 mg Current Unavailable Manufacturing 29/07/2025 lacosamide Tablet, film coated 200 mg Resolved Available Manufacturing 29/07/2025 dexmedetomidine hydrochloride Injection, concentrated 118 microgram/mL Resolved Available Manufacturing 29/07/2025 topotecan hydrochloride Injection, concentrated 4.346 mg Anticipated Available Unexpected increase in consumer demand 29/07/2025 methylphenidate hydrochloride Capsule, hard 20 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 29/07/2025 Teriparatide Injection, solution .25 mg/mL Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 29/07/2025 framycetin sulfate Eye and Ear Drops 5 mg/mL Current Limited Availability Transport / Logistic issues / Storage capacity issues 29/07/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 29/07/2025 phenoxybenzamine hydrochloride Capsule, hard 10 mg Current Unavailable Manufacturing 28/07/2025 tetrabenazine Tablet, uncoated 25 mg Anticipated Available Manufacturing 28/07/2025 ondansetron hydrochloride dihydrate Tablet, film coated 9.972 mg Current Limited Availability Manufacturing 28/07/2025 metronidazole Tablet, uncoated 400 mg Current Limited Availability Manufacturing 28/07/2025 hydrochlorothiazide~irbesartan Tablet, film coated 12.5 mg~300 mg Resolved Available Manufacturing 28/07/2025 linezolid Tablet, film coated 600 mg Current Unavailable Manufacturing 28/07/2025 hydrocortisone Tablet, uncoated 20 mg Resolved Available Manufacturing 28/07/2025 nizatidine Capsule, hard 150 mg Current Unavailable Manufacturing 28/07/2025 hydrocortisone Tablet, uncoated 20 mg Resolved Available Manufacturing 28/07/2025 larotrectinib sulfate Capsule, hard 30.7 mg Current Limited Availability Unexpected increase in consumer demand 28/07/2025 montelukast sodium Tablet, film coated 10.4 mg Resolved Available Manufacturing 28/07/2025 dorzolamide hydrochloride~timolol maleate Eye Drops, solution 22.26 mg/mL~6.83 mg/mL Resolved Available Manufacturing 28/07/2025 heparin sodium Injection, solution 5000 IU Resolved Available Transport / Logistic issues / Storage capacity issues 28/07/2025 methylphenidate hydrochloride Capsule, modified release 20 mg Current Limited Availability Manufacturing 28/07/2025
ドイツ
- 2025.08.18
Active ingredients Report type Date of last message Type of reason AM designation Sertraline hydrochloride Change notification 15.08.2025 Other Sertraline TAD 100 mg film-coated tablets Sertraline hydrochloride Change notification 15.08.2025 Other Sertraline TAD 50 mg film-coated tablets Phenoxybenzamine hydrochloride Change notification 15.08.2025 Other Dibenzyran 10 Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 15.08.2025 Other Atorvastatin Micro Labs 20 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 15.08.2025 Other Atorvastatin Micro Labs 40 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 15.08.2025 Other Atorvastatin Micro Labs 80 mg film-coated tablets Rifampicin Change notification 15.08.2025 Production problem EREMFAT 450 mg Acetylcholine chloride Change notification 15.08.2025 Production problem Miochol-E powder and solvent for the preparation of an instillation solution for intraocular use Azithromycin dihydrate Change notification 15.08.2025 Other Azithromycin AL 250 mg film-coated tablets Galantamine hydrobromide Change notification 14.08.2025 Production problem Galantamine Heumann 24 mg hard capsules, delayed release Quetiapine fumarate (Ph.Eur.) Change notification 14.08.2025 Production problem Quetiapine Heumann retard 200 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 14.08.2025 Production problem Quetiapine Heumann retard 150 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 14.08.2025 Production problem Quetiapine Heumann retard 50 mg prolonged-release tablets Sodium diphosphate decahydrate for the manufacture of radioactive medicinal products Initial 14.08.2025 Other Technescan PYP Tobramycin Change notification 14.08.2025 Production problem TOBI Podhaler 28 mg hard capsules with powder for inhalation – OP224(4×56) Alprazolam Initial 14.08.2025 Other Alprazolam-ratiopharm 1.0 mg tablets Emtricitabine; tenofovir disoproxil maleate Change notification 14.08.2025 Other Emtricitabine/tenofovir disoproxil Mylan 200 mg/245 mg film-coated tablets – OP30(Fl) Naloxegol oxalate Initial 13.08.2025 Other Moventig 25 mg film-coated tablets – OP100(100×1) Isoniazid Change notification 13.08.2025 Other Isozid 200 mg Methyl (5-amino-4-oxopentanoate) hydrochloride Change notification 12.08.2025 Other Metvix 160 mg/g cream Olanzapine Initial 12.08.2025 Production problem Olanzapine Glenmark 5 mg tablets – OP70 Olanzapine Initial 12.08.2025 Production problem Olanzapine Glenmark 2.5 mg tablets – OP70 Olanzapine Initial 12.08.2025 Production problem Olanzapine Glenmark 2.5 mg tablets – OP56 Olanzapine Initial 12.08.2025 Production problem Olanzapine Glenmark 10 mg tablets – OP70 Olanzapine Initial 12.08.2025 Production problem Olanzapine Glenmark 10 mg tablets – OP56 Trazodone hydrochloride Change notification 12.08.2025 Production problem Trazodone Glenmark 100 mg tablets Rizatriptan benzoate Change notification 12.08.2025 Production problem Rizatriptan Glenmark 10 mg tablets Rizatriptan benzoate Change notification 12.08.2025 Production problem Rizatriptan Glenmark 10 mg orodispersible tablets Rizatriptan benzoate Change notification 12.08.2025 Production problem Rizatriptan Glenmark 5 mg orodispersible tablets Rizatriptan benzoate Change notification 12.08.2025 Production problem Rizatriptan Glenmark 5 mg tablets Quetiapine fumarate (Ph.Eur.) Initial 12.08.2025 Production problem Quetiapine Glenmark 300 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 12.08.2025 Production problem Quetiapine Glenmark 400 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 12.08.2025 Production problem Quetiapine Glenmark 200 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 12.08.2025 Production problem Quetiapine Glenmark 150 mg prolonged-release tablets Mometasone furoate (Ph.Eur.) Change notification 12.08.2025 Production problem Mometasone Glenmark 1 mg/g ointment Linezolid Change notification 12.08.2025 Production problem Linezolid Glenmark 600 mg film-coated tablets Galantamine hydrobromide Change notification 12.08.2025 Production problem Galantamine Glenmark 24 mg hard capsules, delayed release Galantamine hydrobromide Change notification 12.08.2025 Production problem Galantamine Glenmark 8 mg hard capsules, delayed release Galantamine hydrobromide Change notification 12.08.2025 Production problem Galantamine Glenmark 16 mg hard capsules, delayed release Pirfenidone Initial 12.08.2025 Production problem Pirfenidone Accord 801 mg film-coated tablets Ezetimibe; Simvastatin Initial 12.08.2025 Production problem Ezetimibe/Simvastatin Glenmark 10 mg/20 mg tablets Alprazolam Initial 12.08.2025 Other Alprazolam – 1 A Pharma 1 mg tablets Alprazolam Initial 12.08.2025 Other Alprazolam – 1 A Pharma 0.5 mg tablets Gabapentin Initial 12.08.2025 Production problem Gabapentin Holsten 800 mg film-coated tablets Gabapentin Initial 12.08.2025 Other Gabapentin Holsten 100 mg hard capsules Doxepine hydrochloride (Ph.Eur.) Initial 12.08.2025 Other Doxepin 75 Holsten Zoledronic acid monohydrate Change notification 12.08.2025 Production problem Zoledronic acid Mylan 4 mg/5 ml concentrate for solution for infusion – OP5ml Rifampicin Initial 12.08.2025 Other EREMFAT 300 mg Vancomycin hydrochloride Initial 12.08.2025 Other Vancomycin “Lederle” 1000 mg Urapidil Change notification 12.08.2025 Other Urapidil PUREN 90 mg prolonged-release capsules Topiramate Change notification 12.08.2025 Production problem Topiramate PUREN 100 mg film-coated tablets Sitagliptin hydrochloride monohydrate Change notification 12.08.2025 Production problem Sitagliptin PUREN 50 mg film-coated tablets Sitagliptin hydrochloride monohydrate Change notification 12.08.2025 Production problem Sitagliptin Aurobindo 25 mg film-coated tablets Rizatriptan benzoate Change notification 12.08.2025 Production problem Rizatriptan PUREN 5 mg tablets Rizatriptan benzoate Change notification 12.08.2025 Other Rizatriptan PUREN 10 mg tablets Rizatriptan benzoate Change notification 12.08.2025 Other Rizatriptan Aurobindo 10 mg orodispersible tablets Risperidone Change notification 12.08.2025 Other Risperidone PUREN 1 mg film-coated tablets Risperidone Change notification 12.08.2025 Other Risperidone Aurobindo 1 mg film-coated tablets Docetaxel Change notification 12.08.2025 Other Docetaxel Aurobindo 20 mg/ml concentrate for solution for infusion Nevirapine Change notification 12.08.2025 Other Nevirapine Aurobindo 400 mg prolonged-release tablets Moxifloxacin hydrochloride (Ph.Eur.) (with information on water content (1:x)) Change notification 12.08.2025 Production problem Moxifloxacin Aurobindo 400 mg film-coated tablets Moxifloxacin hydrochloride (Ph.Eur.) (with information on water content (1:x)) Change notification 12.08.2025 Production problem Moxifloxacin PUREN 400 mg film-coated tablets Ibuprofen Change notification 12.08.2025 Other IBU-PUREN acute 400 mg film-coated tablets Oxycodone hydrochloride (Ph.Eur.) Change notification 11.08.2025 Other Oxygesic 5 mg Paliperidone palmitate Change notification 11.08.2025 Production problem Paliperidone Advanz Pharma 25 mg Depot injection suspension in a pre-filled syringe Paliperidone palmitate Change notification 11.08.2025 Production problem Paliperidone Advanz Pharma 50 mg depot injection suspension in a pre-filled syringe Hydromorphone hydrochloride Change notification 11.08.2025 Other Hydromorphone HEXAL 2.6 mg hard capsules Insulin aspart Initial 11.08.2025 Other NovoRapid PumpCart 100 E/ml injection solution in cartridge – OP[5x(5×1.6ml)] Chlortalidone Change notification 11.08.2025 Other Chlortalidone HEXAL 25 mg tablets Chlortalidone Change notification 11.08.2025 Other Chlortalidone HEXAL 50 mg tablets Sufentanil Initial 11.08.2025 Production problem Sufentanil-hameln 50 micrograms/ml injection/infusion solution Oxycodone hydrochloride (Ph.Eur.) Initial 11.08.2025 Other Oxycodone-HCl HEXAL 40 mg prolonged-release tablets Oxycodone hydrochloride (Ph.Eur.) Initial 11.08.2025 Other Oxycodone-HCl HEXAL 20 mg prolonged-release tablets Oxycodone hydrochloride (Ph.Eur.) Initial 11.08.2025 Other Oxycodone-HCl HEXAL 10 mg prolonged-release tablets Oxycodone hydrochloride (Ph.Eur.) Initial 11.08.2025 Other Oxycodone-HCl HEXAL 5 mg prolonged-release tablets Hydromorphone hydrochloride Change notification 11.08.2025 Other Hydromorphone HCl PUREN 4 mg hard capsules, delayed release Escitalopram oxalate Change notification 11.08.2025 Other Escitalopram Aurobindo 10 mg film-coated tablets Etoricoxib Change notification 11.08.2025 Other Etoricoxib PUREN 120 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 11.08.2025 Other Atorvastatin PUREN 40 mg film-coated tablets Gabapentin Change notification 11.08.2025 Other Gabapentin Aurobindo 400 mg hard capsules Prasugrel Change notification 11.08.2025 Production problem Prasugrel PUREN 5 mg film-coated tablets Lamotrigine Change notification 11.08.2025 Production problem Lamotrigine Aurobindo 50 mg tablets Ramipril Change notification 11.08.2025 Other Ramipril PUREN 5 mg tablets Pregabalin Change notification 11.08.2025 Other Pregabalin Aurobindo 25 mg hard capsules Pregabalin Change notification 11.08.2025 Other Pregabalin PUREN 100 mg hard capsules - 2025.08.11
Active ingredients Report type Date of last message Type of reason AM designation Pramipexole dihydrochloride monohydrate Change notification 10.08.2025 Other Pramipexole PUREN 0.18 mg tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 10.08.2025 Other Atorvastatin PUREN 10 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 10.08.2025 Other Atorvastatin PUREN 20 mg film-coated tablets Paliperidone palmitate Change notification 08.08.2025 Other Paliperidone AL 150 mg depot injection suspension in a pre-filled syringe Quetiapine fumarate (Ph.Eur.) Change notification 08.08.2025 Other Quetiapine-neuraxpharm 600 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 08.08.2025 Other Quetiapine-neuraxpharm 400 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 08.08.2025 Other Quetiapine-neuraxpharm 300 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 08.08.2025 Other Quetiapine-neuraxpharm 200 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 08.08.2025 Other Quetiapine-neuraxpharm 150 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 08.08.2025 Other Quetiapine-neuraxpharm 50 mg prolonged-release tablets Levomepromazine hydrochloride Initial report 08.08.2025 Other Levomepromazine-neuraxpharm 25 mg/ml solution for injection Phenobarbital Change notification 08.08.2025 Production problem Phenobarbital-neuraxpharm 100 mg Phenobarbital Change notification 08.08.2025 Production problem Phenobarbital-neuraxpharm 15 mg Methylphenidate hydrochloride Change notification 08.08.2025 Other Methylphenidate hydrochloride-neuraxpharm 27 mg prolonged-release tablets Haloperidol decanoate Change notification 08.08.2025 Production problem Haloperidol-neuraxpharm decanoate 100 mg/ml Haloperidol decanoate Change notification 08.08.2025 Production problem Haloperidol-neuraxpharm decanoate 50 mg/ml Galantamine hydrobromide Change notification 08.08.2025 Other Galantamine-neuraxpharm 24 mg hard capsules, delayed release Galantamine hydrobromide Change notification 08.08.2025 Other Galantamine-neuraxpharm 16 mg Hard capsules, delayed release Galantamine hydrobromide Change notification 08.08.2025 Other Galantamine-neuraxpharm 8 mg hard capsules, delayed release Atomoxetine hydrochloride Change notification 08.08.2025 Production problem Atomoxetine-neuraxpharm 100 mg hard capsules Atomoxetine hydrochloride Change notification 08.08.2025 Production problem Atomoxetine-neuraxpharm 80 mg hard capsules Atomoxetine hydrochloride Change notification 08.08.2025 Production problem Atomoxetine-neuraxpharm 40 mg hard capsules Atomoxetine hydrochloride Change notification 08.08.2025 Production problem Atomoxetine-neuraxpharm 25 mg hard capsules Atomoxetine hydrochloride Change notification 08.08.2025 Production problem Atomoxetine-neuraxpharm 18 mg hard capsules Atomoxetine hydrochloride Change notification 08.08.2025 Production problem Atomoxetine-neuraxpharm 10 mg hard capsules Atomoxetine hydrochloride Change notification 08.08.2025 Production problem Atomoxetine-neuraxpharm 60 mg hard capsules Nintedanib Initial report 07.08.2025 Other Ofev Von Willebrand factor Initial report 07.08.2025 Other WILLFACT 1000 IU Fusidic acid (Ph.Eur.) Change notification 07.08.2025 Production problem Fucithalmic 10 mg/g eye drops Calcium acetate hydrate ((with information on water content (1:x))) Change notification 07.08.2025 Production problem Renacet 950 mg Quetiapine fumarate (Ph.Eur.) Change notification 07.08.2025 Other Seroquel Prolong 50 mg prolonged-release tablets Fluoxetine hydrochloride Initial report 06.08.2025 Other Fluoxetine Micro Labs 60 mg hard capsules Fluoxetine hydrochloride Initial report 06.08.2025 Other Fluoxetine Micro Labs 40 mg hard capsules Fluoxetine hydrochloride Initial report 06.08.2025 Other Fluoxetine Micro Labs 30 mg hard capsules Fluoxetine hydrochloride Initial report 06.08.2025 Other Fluoxetine Micro Labs 20 mg hard capsules Fluoxetine hydrochloride Initial report 06.08.2025 Other Fluoxetine Micro Labs 10 mg hard capsules Trandolapril; verapamil hydrochloride Change notification 06.08.2025 Other Tarka 180 mg/ 2 mg modified-release tablets Brivaracetam Change notification 06.08.2025 Production problem Briviact 50 mg film-coated tablets – OP56 Quetiapine fumarate (Ph.Eur.) Change notification 06.08.2025 Other Seroquel Prolong 400 mg prolonged-release tablets Cinacalcet hydrochloride Change notification 06.08.2025 Other Cinacalcet-ratiopharm 30 mg film-coated tablets Atorvastatin hemicalcium Change notification 06.08.2025 Other Atorvastatin – 1A Pharma 80 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Initial 06.08.2025 Other Atorvastatin-1A Pharma 20 mg film-coated tablets Pramipexole dihydrochloride monohydrate Change notification 05.08.2025 Production problem Pramipexole STADA 0.52 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 05.08.2025 Other Seroquel Prolong 300 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 05.08.2025 Other Seroquel Prolong 200 mg prolonged-release tablets Ipratropium bromide (Ph.Eur.); salbutamol sulfate Change notification 05.08.2025 Production problem COMBIPRASAL 0.5 mg / 2.5 mg solution for nebulizer Reproterol hydrochloride Change notification 05.08.2025 Production problem Bronchospasmin 10 ml solution for injection Tropicamide Change notification 05.08.2025 Production problem Mydriaticum Stulln UD Carbamazepine Initial 05.08.2025 Production problem Tegretal 200 mg retard Olanzapine embonate monohydrate Change notification 05.08.2025 Production problem ZYPADHERA 405 mg powder and solvent for the preparation of a depot injection suspension – OP (931 mg + 3 ml) Insulin aspart Change notification 05.08.2025 Other NovoMix 30 FlexPen 100 IU/ml injection suspension in pre-filled syringe – OP(10x3ml) Human insulin (with manufacturing details) Change notification 05.08.2025 Other Actrapid Penfill 100 IU/ml injection solution in cylinder ampoule – OP(10x3ml) Olanzapine embonate monohydrate Change notification 05.08.2025 Production problem ZYPADHERA 300 mg powder and solvent for the preparation of a depot injection suspension – OP(690mg+3ml) Isoniazid Initial 05.08.2025 Other Isozid 200 mg Prednisolone acetate Change notification 05.08.2025 Production problem Prednifluid 10 mg/ml eye drop suspension Atovaquone; proguanil hydrochloride Initial 04.08.2025 Other Malarone Junior film-coated tablets Mupirocin calcium (Ph.Eur.) Change notification 04.08.2025 Production problem Turixin Melperone hydrochloride Change notification 04.08.2025 Production problem Melperone Aristo 100 mg film-coated tablets Paliperidone palmitate Initial 04.08.2025 Other Paliperidone AL 50 mg depot injection suspension in a pre-filled syringe Iron (II) glycine sulfate complex Change notification 04.08.2025 Production problem Ferro sanol 30 mg/ml drops Clarithromycin Change notification 04.08.2025 Production problem CLARITHROMYCIN BASICS 250 mg/5 ml granules for oral suspension Esomeprazole hemimagnesium Change notification 04.08.2025 Production problem ESOMEPRAZOLE BASICS 40 mg gastro-resistant hard capsules Esomeprazole hemimagnesium Change notification 04.08.2025 Production problem ESOMEPRAZOLE BASICS 20 mg enteric-coated hard capsules Fluoxetine hydrochloride Change notification 04.08.2025 Production problem Fluoxetine Stada 20 mg tablets for oral suspension Gentamicin sulfate Change notification 04.08.2025 Production problem Gentamicin POS - 2025.08.04
フランス
- 2025.08.18
Active ingredients Statut Update Specialty bumetanide Supply tension 14/08/2025 Burinex 2 mg/4 ml IV, solution for injection in ampoule alglucosidase alfa ((mammalian/hamster/cho cells)) Supply tension 14/08/2025 Myozyme 50 mg, powder for solution for diluted infusion basiliximab (mammal/mouse/Sp2/O) Available for use 14/08/2025 Simulect 20 mg, powder and solvent for solution for injection or infusion glucagon (hydrochloride) Supply tension 14/08/2025 GlucaGen Kit 1 mg/ml, powder and solvent for solution for injection bezafibrate Supply tension 13/08/2025 Befizal L.P. 400 mg, sustainedrelease coated tablet methylphenidate hydrochloride Supply tension 13/08/2025 Concerta LP, extendedrelease tablet methylprednisolone (hydrogen succinate) Supply tension 13/08/2025 Methylprednisolone Viatris 40 mg, powder for solution for injection (IMIV) methylprednisolone (hydrogen succinate) Out of stock 13/08/2025 Methylprednisolone Viatris 20 mg, powder for solution for injection (IMIV) naloxegol (oxalate) Available for use 13/08/2025 Moventig 25 mg, filmcoated tablet naloxegol (oxalate) Available for use 13/08/2025 Moventig 12.5 mg, filmcoated tablet betamethasone (dipropionate), betamethasone (sodium phosphate) Supply tension 12/08/2025 Diprostene, suspension for injection in prefilled syringe chlorpromazine (hydrochloride) Supply tension 12/08/2025 Largactil 100 mg, scored filmcoated tablet medroxyprogesterone Supply tension 11/08/2025 Depo Prodasone 500 mg, injectable suspension – bromfenac sodium sesquihydrate Supply tension 11/08/2025 Yellox 0.9 mg/ml, eye drops solution methotrexate Available for use 11/08/2025 Methotrexate Teva 10 per cent (5 g/50 mL), solution for injection levofloxacin Available for use 11/08/2025 Specialties based on Levofloxacin 500 mg scored filmcoated tablet temozolomide Supply tension 11/08/2025 Temodal 2.5 mg/ml, powder for solution for infusion bosentan monohydrate Available for use 11/08/2025 Bosentan Viatris 125 mg, filmcoated tablet - 2025.08.11
Active ingredients Statut Update Specialty esketamine (hydrochloride) Supply voltage 08/08/2025 Eskesia 5 mg/mL, solution for injection/infusion 10 glass ampoule(s) of 5 ml tadalafil available again 08/08/2025 Tadalafil Quiver 20 mg, filmcoated tablet methylprednisolone (hydrogen succinate) Out of stock 08/08/2025 Methylprednisolone Viatris 40 mg, powder for solution for injection (IMIV) methylprednisolone (hydrogen succinate) Supply voltage 08/08/2025 Methylprednisolone Viatris 120 mg, powder for solution for injection (IMIV) pancreas powder Supply voltage 07/08/2025 Eurobiol 40 000 U, gastroresistant capsule ondansetron available again 07/08/2025 Zophren 4 mg/5 ml, syrup emtricitabine/tenofovir disoproxil Supply voltage 07/08/2025 Speciality based on emtricitabine/tenofovir disoproxil 200 mg/245 mg, filmcoated tablet arsenic trioxide Marketing discontinuation 04/08/2025 Arsenic Trioxide Accord 1 mg /ml, dilutable solution for infusion - 2025.08.04
Active ingredients Status Updated Specialty human protein C Supply tension 01/08/2025 Protexel 50 IU/mL, powder and solvent for solution for injection vincristine (sulfate) Supply tension 31/07/2025 Oncovin 1 mg, solution for injection demeclocycline hydrochloride Out of stock 31/07/2025 Alkonatrem 150 mg, capsule methylphenidate (hydrochloride) Supply tension 31/07/2025 Methylphenidate Viatris LP, extended release tablet maprotiline (hydrochloride) Out of stock 31/07/2025 Ludiomil 25 and 75 mg, film coated tablet bosentan monohydrate Supply tension 30/07/2025 Bosentan Viatris 125 mg, film coated tablet bosentan monohydrate Supply tension 30/07/2025 Tracleer 125 mg, film coated tablet bosentan monohydrate Out of stock 30/07/2025 Bosentan Arrow 125 mg, film coated tablet fusidic acid Readily available 30/07/2025 Fucithalmic 1%, ophthalmic gel methylphenidate (hydrochloride) Supply tension 30/07/2025 Methylphenidate Biogaran, extended release tablet glucagon (hydrochloride) Out of stock 30/07/2025 GlucaGen Kit 1 mg/ml, powder and solvent for solution for injection diazoxide Readily available 30/07/2025 Proglicem 25 mg, capsule adrenaline Supply tension 29/07/2025 Epipen, prefilled injectable solution timolol (maleate), travoprost Readily available 29/07/2025 Travoprost/Timolol 40 micrograms/mL + 5 mg/mL, eye drops, solution
英国
- 2025.08.05
Shortage of antimicrobial agents used in Tuberculosis (TB) treatment
The following antimicrobial medicines used to treat tuberculosis (TB) will be intermittently available until at least the end of 2025:
Rifampicin 150mg and 300mg capsules
Rifampicin 600mg IV solution for infusion
Rifampicin 100mg/5ml oral suspension
Rifinah® 300 tablets (rifampicin 300mg / isoniazid 150mg)
Rifater® tablets (rifampicin 120mg / isoniazid 50mg/ pyrazinamide 300mg)
Voractiv® tablets (rifampicin 150mg/ isoniazid 75mg / pyrazinamide 400mg / ethambutol 275mg)
Pyrazinamide 500mg tabletsEthambutol tablets, Isoniazid tablets, and Rifinah® 150 tablets (rifampicin 150 mg / isoniazid 100 mg) and Mycobutin® (rifabutin) 150mg capsules remain available but cannot support a full increase in demand.
Source: Department of Health and Social Care
EU
EUの情報はありません。