更新された供給不足状況を示しています。
ある時点での供給不足の全体的状況は「供給関連情報」に定期的にアップします。
2025年12月
- 2025.12.16
Medicine supply notification: Nifedipine (Fortipine® LA) 40mg modified-release tablets
2025年12月8日、保健・社会福祉省（Department of Health and Social Care：DHSC）は、Nifedipine (Fortipine® LA) 40mg徐放性錠の医薬品供給通知（medicine supply notification）を発出した。
- Nifedipine (Fortipine® LA)40mg徐放性錠剤は現在在庫切れ。再入荷日は未定。
- 他のブランドのNifedipin20mg徐放性錠剤は引き続き入手可能であり、需要増加に対応可能。
- Nifedipine (Coracten® SR) 20mg徐放性カプセルは引き続き入手可能であり、需要増加に対応可能。
- 2025.12.15
Active ingredients Message type Date of last message Type of reason AM designation Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y) Change notification 12.12.2025 Other Ferrlecit 40 mg Clomipramine hydrochloride Initial report 12.12.2025 Other Clomipramine-neuraxpharm 75 mg retard Epoetin zeta Initial report 12.12.2025 Other Retacrit 40,000 IU/1 ml solution for injection in pre-filled syringe Epoetin zeta Initial report 12.12.2025 Other Retacrit 40,000 IU/1 ml solution for injection in pre-filled syringe Atorvastatin calcium trihydrate (Ph.Eur.) Initial report 11.12.2025 Other Atorvastatin Micro Labs 10 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 11.12.2025 Other Atorvastatin Micro Labs 30 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 11.12.2025 Other Atorvastatin Micro Labs 60 mg film-coated tablets Fluoxetine hydrochloride Change notification 11.12.2025 Other Fluoxetine Micro Labs 60 mg hard capsules Fluoxetine hydrochloride Change notification 11.12.2025 Other Fluoxetine Micro Labs 30 mg hard capsules Quetiapine fumarate (Ph.Eur.) Change notification 11.12.2025 Other Quetiapine AL 200 mg prolonged-release tablets Prednicarbate Change notification 11.12.2025 Other Prednicarbate acis solution Zoledronic acid monohydrate Initial report 11.12.2025 Other Zoledronic acid AL 4 mg/100 ml infusion solution Ibandronate sodium monohydrate Initial report 11.12.2025 Other Ibandronic acid AL 3 mg solution for injection in a pre-filled syringe Fibrinogen, human Initial report 10.12.2025 Other Fibryga Sodium (hydrocortisone-21-succinate) Change notification 10.12.2025 Production problem Hydrocortisone PANPHARMA 100 mg Methylphenidate hydrochloride Change notification 10.12.2025 Other CONCERTA 54 mg prolonged-release tablets Methylphenidate hydrochloride Change notification 10.12.2025 Other CONCERTA 36 mg prolonged-release tablets Methylphenidate hydrochloride Change notification 10.12.2025 Other CONCERTA 27 mg prolonged-release tablets Methylphenidate hydrochloride Change notification 10.12.2025 Other CONCERTA 18 mg prolonged-release tablets Dimenhydrinate Initial report 10.12.2025 Production problem Dimenhydrinate PANPHARMA 6.2 mg/ml solution for injection (i.v.) Metformin hydrochloride Initial report 10.12.2025 Other Metformin 500 – 1 A Pharma Candesartan cilexetil Initial report 10.12.2025 Other Blopress 16 mg Colistimethate sodium Initial report 10.12.2025 Production problem Colistin CF Risperidone Change notification 10.12.2025 Production problem Risperidone-ratiopharm 50 mg powder and solvent for the preparation of a depot injection suspension Risperidone Change notification 10.12.2025 Production problem Risperidone-ratiopharm 37.5 mg powder and solvent for the preparation of a depot injection suspension Risperidone Change notification 10.12.2025 Production problem Risperidone-ratiopharm 25 mg powder and solvent for the preparation of a depot injection suspension Ribavirin Change notification 10.12.2025 Production problem Ribavirin-ratiopharm 200 mg film-coated tablets Ribavirin Change notification 10.12.2025 Other Ribavirin-ratiopharm 400 mg film-coated tablets Levothyroxine sodium Initial report 10.12.2025 Other L-thyroxine-Na-ratiopharm 50 microgram tablets Levothyroxine sodium Initial report 10.12.2025 Other L-Thyroxine-Na-ratiopharm 25 microgram tablets Isoniazid; pyridoxine hydrochloride Initial report 09.12.2025 Other Isozid comp. 200 mg N Isoniazid Initial report 09.12.2025 Other Isozid 0.5 N Pyrazinamide Initial report 09.12.2025 Production problem Pyrafat 500mg Dapsone Initial report 09.12.2025 Production problem Dapson-Fatol Filgrastim Initial report 09.12.2025 Other Nivestim 12 million E/0.2 ml injection/infusion solution – OP (5×0.2 ml) Adalimumab Initial report 09.12.2025 Other Amsparity Adalimumab Initial report 09.12.2025 Other Amsparity Adalimumab Initial report 09.12.2025 Other Amsparity Adalimumab Initial report 09.12.2025 Other Amsparity Risedronate sodium 2.5 hydrate (Ph.Eur.) Initial report 09.12.2025 Other Risedronate Aurobindo once weekly 35 mg film-coated tablets Terazosin hydrochloride dihydrate Change notification 09.12.2025 Other Heitrin 1mg Terazosin hydrochloride dihydrate Change notification 09.12.2025 Other Heitrin 5mg Terazosin hydrochloride dihydrate Change notification 09.12.2025 Other Heitrin 2 mg Metamizole sodium monohydrate Initial report 08.12.2025 Production problem Novaminsulfon – 1 A Pharma Drops Methylphenidate hydrochloride Initial report 08.12.2025 Other Equasym Retard 40 mg hard capsules with modified release Atorvastatin calcium trihydrate (Ph.Eur.) Initial report 08.12.2025 Other Atorvastatin – 1A Pharma 40 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Initial report 08.12.2025 Other Atorvastatin – 1A Pharma 10 mg film-coated tablets Quetiapine fumarate (Ph.Eur.) Change notification 08.12.2025 Other Seroquel Prolong 50 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 08.12.2025 Other Seroquel Prolong 300 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 08.12.2025 Other Seroquel Prolong 200 mg prolonged-release tablets - 2025.12.15
Active ingredients Status Update Specialty propranolol hydrochloride Supply tension 12/12/2025 Propranolol 40 mg tablets prednisolone (sodium metasulfobenzoate) Return to availability 12/12/2025 Prednisolone 5 mg and 20 mg, orodispersible tablet and effervescent tablet prednisone Return to availability 12/12/2025 Prednisone 5 mg and 20 mg, breakable tablet danazol Return to availability 12/12/2025 Danatrol 200 mg, capsule prednisolone (acetate) Return to availability 11/12/2025 Hydrocortancyl 2.5 percent, injectable suspension bromfenac sodium sesquihydrate Return to availability 11/12/2025 Yellox 0.9 mg/mL, eye drops, solution pristinamycin Return to availability 10/12/2025 Pyostacin 500 mg, film-coated tablet fluorouracil Supply tension 09/12/2025 Fluorouracil Accord 50 mg/mL, solution for dilution for infusion, 5 mL, 20 mL, and 100 mL vials ifosfamide Supply tension 08/12/2025 Holoxan 2000 mg, powder for parenteral use Normal human immunoglobulin (IgG) Supply tension 08/12/2025 Normal human immunoglobulin IV and SC (based on) lithium (carbonate) Supply tension 08/12/2025 Teralithe 250 mg, breakable tablet clomipramine (hydrochloride) Return to availability 08/12/2025 Anafranil 25 mg, coated tablet varenicline (tartrate) Supply tension 08/12/2025 Champix 0.5 mg and 1 mg, film-coated tablet - 2025.12.15
Ingredients Product Name Formulation Report Category Report Date Penciclovir Penciclovir Cream (Penciclovir) Skin Cream Supply Discontinuation 2025-12-12 Temozolomide Temozolomide Capsules 20 milligrams (Temozolomide) Hard Capsule, Powder Supply Shortage 2025-12-11 Bambuterol Hydrochloride Bambec Tablet 10mg (Bambuterol Hydrochloride) Najeong Supply Discontinuation 2025-12-10 Piperonyl butoxide, Pyrethrin extract Gammarin Diac Shampoo Supply Discontinuation 2025-12-09 Hydrocortisone Hydrocortisone Cream (Export Name: Hydrocortisone 1% Cream Max Strength, Hydrocortisone Cream) Skin Cream Supply Discontinuation 2025-12-09 House Dust Mite Extract Challergan Sublingual Solution (House Dust Mite Extract) (Maintenance Therapy) Oral Solution Supply Discontinuation 2025-12-08 House Dust Mite Extract Challergan Sublingual Solution (House Dust Mite Tablet Extract) (Initiation Therapy) Oral Solution Supply Discontinuation 2025-12-08 - 2025.12.15
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated gabapentin Capsule, hard 400 mg Current Limited Availability Manufacturing 12/12/2025 prazosin hydrochloride Tablet, uncoated 5.476 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 12/12/2025 clindamycin phosphate Injection, solution 0 QS Anticipated Available Manufacturing 12/12/2025 aripiprazole Tablet, uncoated 10 mg Anticipated Available Manufacturing 12/12/2025 tacrolimus monohydrate Capsule, hard 5.112 mg Anticipated Available Manufacturing 12/12/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Limited Availability Manufacturing 12/12/2025 montelukast sodium Tablet, chewable 5.2 mg Anticipated Available Manufacturing 12/12/2025 cisatracurium besilate Injection, solution 14.07 mg Current Limited Availability Manufacturing 12/12/2025 citalopram hydrobromide Tablet, film coated 49.98 mg Anticipated Available Manufacturing 12/12/2025 carbidopa monohydrate~levodopa~entacapone Tablet, film coated 54.1 mg~200 mg~200 mg Current Unavailable Unexpected increase in consumer demand 12/12/2025 Pegvisomant Injection, powder for 10 mg Anticipated Available Manufacturing 12/12/2025 amlodipine besilate~olmesartan medoxomil Tablet, film coated 6.935 mg~40 mg Anticipated Available Manufacturing 12/12/2025 lacosamide Tablet, film coated 150 mg Anticipated Available Manufacturing 12/12/2025 lorazepam Tablet 1 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 12/12/2025 timolol maleate~latanoprost Eye Drops, solution 6.83 mg/mL~.05 mg/mL Current Limited Availability Manufacturing 12/12/2025 paroxetine hydrochloride Tablet, film coated 22.22 mg Current Limited Availability Manufacturing 12/12/2025 ciprofloxacin hydrochloride Tablet, film coated 582.21 mg Anticipated Available Manufacturing 12/12/2025 lamotrigine Tablet, chewable 100 mg Current Unavailable Manufacturing 12/12/2025 lamotrigine Tablet, chewable 200 mg Anticipated Available Manufacturing 12/12/2025 nitrofurantoin Capsule, hard 100 mg Current Limited Availability Unexpected increase in consumer demand 12/12/2025 tofacitinib citrate Solution 1.62 mg/mL Anticipated Available Manufacturing 12/12/2025 ondansetron hydrochloride dihydrate Tablet, film coated 4.986 mg Anticipated Available Manufacturing 12/12/2025 doxepin hydrochloride Capsule, hard 28.25 mg Current Limited Availability Manufacturing 12/12/2025 clonidine hydrochloride Tablet, uncoated 150 microgram Current Limited Availability Manufacturing 12/12/2025 salbutamol sulfate Inhalation, conventional 3 mg Current Unavailable Manufacturing 11/12/2025 salbutamol sulfate Inhalation, conventional 6 mg Current Unavailable Manufacturing 11/12/2025 salbutamol sulfate Inhalation 2.4 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 11/12/2025 nortriptyline Tablet, film coated 10 mg Resolved Available Manufacturing 11/12/2025 bisoprolol fumarate Tablet 2.5 mg Current Unavailable Manufacturing 11/12/2025 ondansetron hydrochloride dihydrate Tablet, film coated 9.972 mg Current Limited Availability Manufacturing 11/12/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Resolved Available Manufacturing 11/12/2025 indapamide hemihydrate Tablet, sugar coated 2.5 mg Current Unavailable Manufacturing 11/12/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 11/12/2025 enalapril maleate Tablet 5 mg Current Unavailable Manufacturing 11/12/2025 levodopa~carbidopa monohydrate~entacapone Tablet, film coated 100 mg~27 mg~200 mg Current Unavailable Unexpected increase in consumer demand 11/12/2025 ezetimibe Tablet, uncoated 10 mg Current Limited Availability Unexpected increase in consumer demand 11/12/2025 irbesartan Tablet, film coated 150 mg Anticipated Available Manufacturing 11/12/2025 tobramycin Inhalation, conventional 60 mg/mL Anticipated Available Manufacturing 11/12/2025 bimatoprost Eye Drops .3 mg/mL Anticipated Available Manufacturing 11/12/2025 erenumab Injection, solution 70 mg Current Limited Availability Unexpected increase in consumer demand 11/12/2025 crisaborole Ointment 2 % w/w Anticipated Available Unexpected increase in consumer demand 11/12/2025 gabapentin Tablet, film coated 600 mg Resolved Available Manufacturing 11/12/2025 sitagliptin hydrochloride monohydrate~metformin hydrochloride Tablet, modified release 56.685 mg~1000 mg Current Unavailable Manufacturing 11/12/2025 nitrofurantoin Capsule, hard 50 mg Anticipated Available Manufacturing 11/12/2025 Teriparatide Injection, solution .25 mg/mL Anticipated Available Manufacturing 11/12/2025 levothyroxine sodium Tablet, uncoated .05 mg Resolved Available Manufacturing 11/12/2025 rifampicin Oral Liquid 20 mg/mL Anticipated Available Unexpected increase in consumer demand 10/12/2025 metformin hydrochloride Tablet, film coated 850 mg Current Unavailable Manufacturing 10/12/2025 lansoprazole Capsule, enteric 30 mg Current Limited Availability Manufacturing 10/12/2025 lamivudine Tablet, film coated 300 mg Current Limited Availability Manufacturing 10/12/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Limited Availability Manufacturing 10/12/2025 isotretinoin Capsule, soft 20 mg Current Unavailable Manufacturing 10/12/2025 azithromycin Injection, powder for 500 mg Current Unavailable Commercial Changes / Commercial viability 10/12/2025 ropivacaine hydrochloride Injection, solution 75 mg Resolved Available Transport / Logistic issues / Storage capacity issues 10/12/2025 ropivacaine hydrochloride Injection, solution 200 mg Resolved Available Transport / Logistic issues / Storage capacity issues 10/12/2025 lurasidone hydrochloride Tablet, film coated 80 mg Discontinued Unavailable Commercial Changes / Commercial viability 10/12/2025 metformin hydrochloride Tablet, film coated 1000 mg Current Unavailable Manufacturing 10/12/2025 isotretinoin Capsule, soft 10 mg Current Limited Availability Manufacturing 10/12/2025 fluorouracil Injection, solution 50 mg/mL Resolved Available Manufacturing 10/12/2025 doxepin hydrochloride Capsule, hard 11.3 mg Current Limited Availability Manufacturing 10/12/2025 aprepitant Capsule, hard 165 mg Anticipated Available Manufacturing 10/12/2025 montelukast sodium Tablet, chewable 5.2 mg Current Unavailable Manufacturing 10/12/2025 isotretinoin Capsule, soft 10 mg Current Unavailable Manufacturing 10/12/2025 perindopril erbumine Tablet, uncoated 2 mg Discontinued Unavailable Commercial Changes / Commercial viability 10/12/2025 perindopril erbumine Tablet, uncoated 4 mg Discontinued Unavailable Commercial Changes / Commercial viability 10/12/2025 levothyroxine sodium Tablet, uncoated 75 microgram Current Unavailable Manufacturing 10/12/2025 levothyroxine sodium Tablet, uncoated 200 microgram Current Unavailable Manufacturing 10/12/2025 tetrabenazine Tablet, uncoated 25 mg Current Unavailable Manufacturing 10/12/2025 isotretinoin Capsule, soft 20 mg Current Unavailable Manufacturing 10/12/2025 isotretinoin Capsule, soft 10 mg Current Limited Availability Manufacturing 10/12/2025 stannous chloride dihydrate Injection, powder for 19.2 microgram/mL Anticipated Available Manufacturing 10/12/2025 perindopril erbumine Tablet, uncoated 8 mg Discontinued Unavailable Commercial Changes / Commercial viability 10/12/2025 ceftazidime pentahydrate Injection, powder for 2.328 g Resolved Available Manufacturing 9/12/2025 hydromorphone hydrochloride Injection, solution 10 mg/mL Discontinued Unavailable Commercial Changes / Commercial viability 9/12/2025 prasugrel Tablet, film coated 5 mg Resolved Available Commercial Changes / Commercial viability 9/12/2025 dantrolene sodium hemiheptahydrate Capsule 25 mg Current Unavailable Manufacturing 9/12/2025 dantrolene sodium hemiheptahydrate Capsule 50 mg Current Unavailable Manufacturing 9/12/2025 eptifibatide Injection, solution 20 mg Current Unavailable Manufacturing 9/12/2025 mefloquine hydrochloride Tablet, uncoated 274.09 mg Anticipated Available Transport / Logistic issues / Storage capacity issues 9/12/2025 alprostadil Injection, solution 500 microgram/mL Anticipated Available Manufacturing 9/12/2025 labetalol hydrochloride Tablet, film coated 100 mg Resolved Available Manufacturing 9/12/2025 desferrioxamine mesilate Injection, powder for 2 g Anticipated Available Manufacturing 9/12/2025 betiatide Injection, powder for 1 mg Current Unavailable Manufacturing 8/12/2025 drospirenone~ethinylestradiol Tablet 3 mg~30 microgram Resolved Available Manufacturing 8/12/2025 milrinone Injection, concentrated 10 mg Current Unavailable Manufacturing 8/12/2025 temozolomide Capsule, hard 20 mg Anticipated Available Manufacturing 8/12/2025 paclitaxel Injection, concentrated 300 mg Resolved Available Manufacturing 8/12/2025 citalopram hydrobromide Tablet, film coated 12.495 mg Current Limited Availability Manufacturing 8/12/2025 pregabalin Capsule, hard 25 mg Resolved Available Manufacturing 8/12/2025 lamotrigine Tablet, uncoated 100 mg Current Unavailable Manufacturing 8/12/2025 hydrocortisone Tablet, uncoated 4 mg Resolved Available Manufacturing 8/12/2025 levothyroxine sodium Tablet, uncoated 100 microgram Current Unavailable Manufacturing 8/12/2025 levothyroxine sodium Tablet, uncoated 50 microgram Current Unavailable Manufacturing 8/12/2025 thiotepa Injection, powder for 15 mg Current Unavailable Commercial Changes / Commercial viability 8/12/2025 thiotepa Injection, powder for 100 mg Current Unavailable Commercial Changes / Commercial viability 8/12/2025 thiotepa Injection, powder for 400 mg Current Unavailable Commercial Changes / Commercial viability 8/12/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 8/12/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 8/12/2025 bleomycin sulfate Injection, powder for 15000 IU Resolved Available Manufacturing 8/12/2025 dexamethasone~framycetin sulfate~gramicidin Ear Drops .5 mg/mL~5 mg/mL~.05 mg/mL Current Limited Availability Manufacturing 8/12/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated .125 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 8/12/2025 midazolam Injection, solution 1 mg/mL Current Unavailable Manufacturing 8/12/2025 simvastatin Tablet, film coated 5 mg Current Limited Availability Manufacturing 8/12/2025 - 2025.12.15
- 2025.12.15
New
December 10, 2025
- Doxercalciferol Injection (Discontinuation)
- Spironolactone Tablet (Discontinuation)
December 08, 2025
- Ampicillin Sodium Injection (Discontinuation)
Updated
December 11, 2025
- Dextrose Monohydrate 10% Injection (Currently in Shortage)
- Dextrose Monohydrate 5% Injection (Currently in Shortage)
- Ropivacaine Hydrochloride Injection (Currently in Shortage)
- Sterile Water Injection (Currently in Shortage)
December 09, 2025
- Dexmedetomidine Hydrochloride Injection (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
December 08, 2025
- Azacitidine Injection (Currently in Shortage)
- Bupivacaine Hydrochloride Injection (Currently in Shortage)
- Dexamethasone Sodium Phosphate Injection (Currently in Shortage)
- Etomidate Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Ropivacaine Hydrochloride Injection (Currently in Shortage)
- 2025.12.08
Ingredients Product Name Formulation Report Category Report Date Polycalcium Perbon Injection 30 Milligrams (Polynate Calcium) Solution for Injection Supply Shortage 2025-12-04 Tobramycin, Dexamethasone Toveson Eye Drops (Tobramycin, Dexamethasone) Suspension Eye Drops Supply Discontinuation 2025-12-02 Dexamethasone (Undifferentiated) Dexa-Hi Tablets 4 Milligrams (Dexamethasone) Najeong Supply Shortage 2025-12-01 Mesalazine Pentasa Extended-Release Granules 1 Gram (Mesalazine) Sustained-Release Granules Supply Shortage 2025-11-26 Hydrocortisone Succinate Sodium Cortisol (Hydrocortisone Succinate Sodium) Freeze-Dried Powder for Suspension Injection Supply Discontinuation 2025-11-25 Pegvisomant SomaVert Injection 15 Milligrams (Pegvisomant) Freeze-Dried Powder for Solution for Injection Supply Shortage 2025-11-20 Pegvisomant SomaVert Injection 10 Milligrams (Pegvisomant) Freeze-Dried Powder for Solution for Injection Supply Shortage 2025-11-20 Pegvisomant Somafert Injection 30 Milligrams (Pegvisomant) Freeze-Dried Powder for Solution for Injection Supply Shortage 2025-11-20 Fentanyl Citrate Actic Oral Tablets 400 Micrograms (Fentanyl Citrate) Trokyze Supply Shortage 2025-11-06 Fentanyl Citrate Actic Oral Tablet 200 Micrograms (Fentanyl Citrate) Trokyze Supply Shortage 2025-11-06 - 2025.12.08
供給不足データベースLieferengpass Datenbankenが一時的にダウンしているようです（12月8日）。
- 2025.12.08
- 2025.12.08
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated levothyroxine sodium Tablet, uncoated 100 microgram Current Unavailable Manufacturing 8/12/2025 levothyroxine sodium Tablet, uncoated 50 microgram Current Unavailable Manufacturing 8/12/2025 thiotepa Injection, powder for 15 mg Current Unavailable Commercial Changes / Commercial viability 8/12/2025 thiotepa Injection, powder for 100 mg Current Unavailable Commercial Changes / Commercial viability 8/12/2025 thiotepa Injection, powder for 400 mg Current Unavailable Commercial Changes / Commercial viability 8/12/2025 simvastatin Tablet, film coated 5 mg Current Limited Availability Manufacturing 8/12/2025 trandolapril Capsule 2 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 5/12/2025 topiramate Tablet, film coated 25 mg Current Unavailable Manufacturing 5/12/2025 pioglitazone hydrochloride Tablet 49.9 mg Resolved Available Manufacturing 5/12/2025 hydrochlorothiazide~valsartan Tablet, film coated 12.5 mg~160 mg Anticipated Available Manufacturing 5/12/2025 phenobarbital Tablet, uncoated 30 mg Current Unavailable Manufacturing 5/12/2025 quetiapine fumarate Tablet, film coated 115.12 mg Resolved Available Commercial Changes / Commercial viability 5/12/2025 quetiapine fumarate Tablet, film coated 345.36 mg Resolved Available Commercial Changes / Commercial viability 5/12/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Unexpected increase in consumer demand 5/12/2025 citalopram hydrobromide Tablet, film coated 12.495 mg Current Limited Availability Manufacturing 5/12/2025 ezetimibe Tablet, uncoated 10 mg Discontinued Reduction in supply until supply is exhausted Unexpected increase in consumer demand 5/12/2025 ezetimibe Tablet, uncoated 10 mg Current Unavailable Unexpected increase in consumer demand 5/12/2025 ezetimibe Tablet, uncoated 10 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 5/12/2025 moxonidine Tablet, film coated 200 microgram Current Limited Availability Commercial Changes / Commercial viability 5/12/2025 mebeverine hydrochloride Tablet, film coated 135 mg Resolved Available Manufacturing 5/12/2025 eplerenone Tablet, film coated 50 mg Current Limited Availability Manufacturing 5/12/2025 eplerenone Tablet, film coated 25 mg Current Limited Availability Manufacturing 5/12/2025 lacosamide Tablet, film coated 50 mg Resolved Available Manufacturing 5/12/2025 lacosamide Tablet, film coated 150 mg Current Unavailable Manufacturing 5/12/2025 amlodipine besilate~olmesartan medoxomil~hydrochlorothiazide Tablet, film coated 13.9 mg~40 mg~12.5 mg Resolved Available Manufacturing 5/12/2025 montelukast sodium Tablet, film coated 10.4 mg Current Limited Availability Manufacturing 5/12/2025 atracurium besilate Injection, solution 10 mg/mL Current Limited Availability Manufacturing 5/12/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated 1 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 5/12/2025 flunitrazepam Tablet, film coated 1 mg Current Limited Availability Manufacturing 5/12/2025 tobramycin Injection, solution 80 mg Current Emergency Supply Only Manufacturing 4/12/2025 phenytoin sodium Injection, solution 250 mg Current Unavailable Manufacturing 4/12/2025 phenytoin sodium Injection, solution 100 mg Current Unavailable Manufacturing 4/12/2025 methylprednisolone sodium succinate Injection, powder for 663.13 mg Anticipated Available Manufacturing 4/12/2025 dantrolene sodium hemiheptahydrate Injection, powder for 20 mg Anticipated Available Manufacturing 4/12/2025 nortriptyline Tablet, film coated 10 mg Anticipated Available Manufacturing 4/12/2025 midazolam Injection, solution 15 mg Current Limited Availability Manufacturing 4/12/2025 midazolam Injection, solution 50 mg Resolved Available Manufacturing 4/12/2025 trimethoprim~sulfamethoxazole Injection, concentrated 16 mg/mL~80 mg/mL Current Unavailable Manufacturing 4/12/2025 bisoprolol fumarate Tablet 5 mg Resolved Available Manufacturing 4/12/2025 rocuronium bromide Injection, solution 50 mg Anticipated Available Manufacturing 4/12/2025 sildenafil citrate Tablet, film coated 140.45 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 4/12/2025 omeprazole Capsule, enteric 20 mg Current Limited Availability Manufacturing 4/12/2025 indapamide hemihydrate~perindopril erbumine Tablet 1.25 mg~4 mg Current Unavailable Manufacturing 4/12/2025 simvastatin~ezetimibe Tablet 10 mg~10 mg Current Unavailable Manufacturing 4/12/2025 simvastatin~ezetimibe Tablet 80 mg~10 mg Anticipated Available Manufacturing 4/12/2025 ezetimibe~simvastatin Tablet 10 mg~20 mg Current Unavailable Manufacturing 4/12/2025 ezetimibe~simvastatin Tablet 10 mg~40 mg Anticipated Available Manufacturing 4/12/2025 acarbose Tablet 50 mg Discontinued Unavailable Commercial Changes / Commercial viability 4/12/2025 acarbose Tablet 100 mg Discontinued Unavailable Commercial Changes / Commercial viability 4/12/2025 paclitaxel Injection, powder for 100 mg Resolved Available Manufacturing 4/12/2025 paroxetine hydrochloride Tablet, film coated 22.22 mg Current Limited Availability Manufacturing 4/12/2025 atorvastatin calcium trihydrate Tablet, film coated 86.751 mg Current Limited Availability Manufacturing 4/12/2025 lamotrigine Tablet, chewable 100 mg Current Unavailable Manufacturing 4/12/2025 daptomycin Injection, powder for 500 mg Current Unavailable Manufacturing 4/12/2025 daptomycin Inhalation, powder for 350 mg Current Unavailable Manufacturing 4/12/2025 isotretinoin Capsule, soft 10 mg Current Limited Availability Manufacturing 4/12/2025 alprostadil Injection, solution 500 microgram/mL Anticipated Available Manufacturing 4/12/2025 rifampicin Capsule, hard 150 mg Resolved Available Manufacturing 4/12/2025 rifampicin Capsule, hard 300 mg Resolved Available Manufacturing 4/12/2025 Insulin lispro Injection, solution 100 IU/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 4/12/2025 Alteplase Diluent, not applicable 10 mg Resolved Available Unexpected increase in consumer demand 4/12/2025 heparin sodium Injection, solution 10 IU/mL Current Unavailable Manufacturing 4/12/2025 nizatidine Capsule 300 mg Current Limited Availability Manufacturing 4/12/2025 sertraline hydrochloride Tablet, film coated 56 mg Anticipated Available Manufacturing 4/12/2025 sertraline hydrochloride Tablet, film coated 112 mg Anticipated Available Manufacturing 4/12/2025 dinoprostone Gel .3333 mg/g Current Emergency Supply Only Manufacturing 4/12/2025 dinoprostone Gel .6667 mg/g Current Emergency Supply Only Manufacturing 4/12/2025 venlafaxine Capsule, modified release 150 mg Current Unavailable Manufacturing 3/12/2025 insulin Injection, suspension 100 IU/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 3/12/2025 insulin Injection, solution 100 IU/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 3/12/2025 glipizide Tablet, uncoated 5 mg Anticipated Available Manufacturing 3/12/2025 ropivacaine hydrochloride Injection, solution 2 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 3/12/2025 ropivacaine hydrochloride Injection, solution 7.5 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 3/12/2025 lansoprazole Tablet, orally disintegrating 15 mg Resolved Available Unexpected increase in consumer demand 3/12/2025 tranexamic acid Tablet, film coated 500 mg Current Unavailable Manufacturing 3/12/2025 tranexamic acid Tablet, film coated 500 mg Current Unavailable Manufacturing 3/12/2025 lamotrigine Tablet, uncoated 100 mg Current Unavailable Manufacturing 3/12/2025 icatibant acetate Injection, solution 31.38 mg Resolved Available Manufacturing 3/12/2025 insulin Injection, suspension 100 IU/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 3/12/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 3/12/2025 ropivacaine hydrochloride Injection, solution 2 mg/mL Current Unavailable Manufacturing 3/12/2025 mianserin hydrochloride Tablet, film coated 20 mg Resolved Available Manufacturing 3/12/2025 labetalol hydrochloride Tablet, film coated 100 mg Current Unavailable Manufacturing 3/12/2025 spironolactone Tablet, film coated 25 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 3/12/2025 tranexamic acid Tablet, film coated 500 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 2/12/2025 sodium nitroprusside Injection, solution 50 mg Resolved Available Manufacturing 2/12/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Limited Availability Manufacturing 2/12/2025 nicorandil Tablet 20 mg Resolved Available Manufacturing 2/12/2025 nicorandil Tablet 10 mg Resolved Available Manufacturing 2/12/2025 hydrocortisone Tablet, uncoated 4 mg Current Unavailable Manufacturing 2/12/2025 daptomycin Injection, powder for 500 mg Resolved Available Manufacturing 2/12/2025 methyldopa sesquihydrate Tablet, film coated 283 mg Resolved Available Manufacturing 2/12/2025 dapsone Tablet, uncoated 25 mg Anticipated Available Manufacturing 1/12/2025 dapsone Tablet, uncoated 100 mg Anticipated Available Manufacturing 1/12/2025 indometacin Suppository, moulded 100 mg Resolved Available Manufacturing 1/12/2025 metoprolol tartrate Injection, solution 1 mg/mL Anticipated Available Manufacturing 1/12/2025 drospirenone~ethinylestradiol Tablet 3 mg~30 microgram Current Limited Availability Manufacturing 1/12/2025 finasteride Tablet, film coated 5 mg Current Limited Availability Manufacturing 1/12/2025 paclitaxel Injection, concentrated 300 mg Current Unavailable Manufacturing 1/12/2025 codeine phosphate hemihydrate Oral Liquid 5 mg/mL Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 1/12/2025 peramivir Injection, concentrated 10 mg/mL Current Unavailable Commercial Changes / Commercial viability 1/12/2025 moxonidine Tablet, film coated 200 microgram Anticipated Available Commercial Changes / Commercial viability 1/12/2025 lacosamide Tablet, film coated 100 mg Current Limited Availability Manufacturing 1/12/2025 lacosamide Tablet, film coated 50 mg Current Limited Availability Manufacturing 1/12/2025 aprepitant Capsule, hard 165 mg Anticipated Available Manufacturing 1/12/2025 montelukast sodium Tablet, chewable 5.2 mg Current Unavailable Manufacturing 1/12/2025 oseltamivir phosphate Capsule, hard 98.524 mg Resolved Available Manufacturing 1/12/2025 finasteride Tablet, film coated 1 mg Current Unavailable Manufacturing 1/12/2025 levothyroxine sodium Tablet, uncoated .05 mg Current Limited Availability Manufacturing 1/12/2025 tetrabenazine Tablet, uncoated 25 mg Current Unavailable Manufacturing 1/12/2025 lidocaine hydrochloride Injection, solution 10 mg/mL Current Limited Availability Manufacturing 1/12/2025 ropivacaine hydrochloride Injection, solution 10 mg/mL Current Limited Availability Manufacturing 1/12/2025 ropivacaine hydrochloride Injection, solution 7.5 mg/mL Current Limited Availability Manufacturing 1/12/2025 ropivacaine hydrochloride Injection, solution 7.5 mg/mL Current Unavailable Manufacturing 1/12/2025 cabergoline Tablet, uncoated 1 mg Anticipated Available Manufacturing 1/12/2025 dalteparin sodium Injection, solution 18000 anti-Xa IU Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 1/12/2025 dosulepin hydrochloride Tablet, film coated 75 mg Resolved Available Manufacturing 1/12/2025 reboxetine mesilate Tablet, uncoated 5.224 mg Anticipated Available Commercial Changes / Commercial viability 1/12/2025 - 2025.12.08
- 2025.12.08
New
December 04, 2025
- Calcitriol Capsule (Discontinuation)
December 03, 2025
- Sodium Chloride 0.9% Injection (Discontinuation)
December 02, 2025
- Posaconazole Injection (Discontinuation)
December 01, 2025
- Nilutamide Tablet (Discontinuation)
- Phenoxybenzamine Hydrochloride Capsule (Discontinuation)
Updated
December 04, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Azacitidine Injection (Currently in Shortage)
- Carboplatin Injection (Currently in Shortage)
- Clindamycin Phosphate Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Ketorolac Tromethamine Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Nitroglycerin Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Streptozocin Powder, For Solution (Currently in Shortage)
December 03, 2025
- Dextrose Monohydrate 5% Injection (Discontinuation)
- Parathyroid Hormone Injection (Currently in Shortage)
December 02, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Carboplatin Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Remifentanil Hydrochloride Injection (Currently in Shortage)
December 01, 2025
- Carboplatin Injection (Discontinuation)
- Sodium Bicarbonate Injection (Currently in Shortage)
- Sterile Water Injection (Currently in Shortage)
- 2025.12.01
Active ingredients Message type Date of last message Type of reason AM designation Moxifloxacin hydrochloride (Ph.Eur.) ((with information on water content (1:x))) Change notification 28.11.2025 Other Moxifloxacin Micro Labs 400 mg film-coated tablets Levothyroxine sodium Change notification 28.11.2025 Production problem L-thyroxine Henning 50 Levothyroxine sodium Change notification 28.11.2025 Production problem L-Thyroxine Aventis 150 microgram tablets Ivermectin Initial report 28.11.2025 Other DRIPONIN 3 mg tablets Escitalopram oxalate Initial report 28.11.2025 Production problem Escitalopram STADA 20 mg film-coated tablets Rifampicin sodium Change notification 28.11.2025 Other Eremfat i.v. 600mg Insulin glargine Change notification 28.11.2025 Other Semglee Insulin glargine Change notification 28.11.2025 Other Semglee 100 units/ml solution for injection in pre-filled pen – OP(5x3ml) Posaconazole Initial report 28.11.2025 Production problem Noxafil Olanzapine Initial report 27.11.2025 Production problem Zyprexa 2.5 mg coated tablets – OP70 (blister pack) Ibuprofen Initial report 27.11.2025 Production problem Ibuprofen Kabi 400 mg solution for infusion Adenosine Change notification 27.11.2025 Production problem Adenosine Altamedics 3 mg/ml solution for injection Adenosine Change notification 27.11.2025 Production problem Adenosine Altamedics 30 mg/10 ml solution for infusion Tacrolimus monohydrate Change notification 27.11.2025 Other Tacrolimus AL 3 mg hard capsules, delayed release Tacrolimus monohydrate Change notification 27.11.2025 Other Tacrolimus AL 0.5 mg hard capsules, delayed release Tacrolimus monohydrate Change notification 27.11.2025 Other Tacrolimus AL 1 mg hard capsules, delayed release Tacrolimus monohydrate Change notification 27.11.2025 Other Tacrolimus AL 5 mg hard capsules, delayed release Quetiapine fumarate (Ph.Eur.) Initial report 27.11.2025 Other Seroquel 25 mg film-coated tablets Quetiapine fumarate (Ph.Eur.) Change notification 27.11.2025 Other Seroquel Prolong 200 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 27.11.2025 Other Seroquel Prolong 300 mg prolonged-release tablets Tolterodine tartrate Change notification 27.11.2025 Other Detrusitol 2 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 27.11.2025 Other Atorvastatin Aristo 80 mg film-coated tablets Primidone Change notification 27.11.2025 Production problem Mylepsinum Doxepin hydrochloride (Ph.Eur.) Change notification 26.11.2025 Production problem Doxepin 25 Holsten Doxepin hydrochloride (Ph.Eur.) Change notification 26.11.2025 Production problem Doxepin 75 Holsten Amlodipine besylate; hydrochlorothiazide; valsartan Change notification 26.11.2025 Other Amlodipine/Valsartan/HCT Holsten 5 mg/160 mg/12.5 mg film-coated tablets Gabapentin Change notification 26.11.2025 Production problem Gabapentin Holsten 800 mg film-coated tablets Prednicarbat Initial report 26.11.2025 Production problem Prednicarbat acis solution Haloperidol decanoate Change notification 26.11.2025 Production problem Haloperidol-neuraxpharm decanoate 100 mg/ml Haloperidol decanoate Change notification 26.11.2025 Production problem Haloperidol-neuraxpharm decanoate 50 mg/ml Dexketoprofen trometamol Change notification 26.11.2025 Production problem Sympal inject 50 mg solution for injection/infusion Pramipexole dihydrochloride monohydrate Change notification 26.11.2025 Other Pramipexole Mylan 3.15 mg prolonged-release tablets Isosorbide mononitrate Change notification 26.11.2025 Production problem ISMN STADA 40 mg tablets Isosorbide mononitrate Change notification 26.11.2025 Production problem ISMN STADA 20 mg tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 25.11.2025 Other Atorvastatin PUREN 40 mg film-coated tablets Rivastigmine hydrogen tartrate Change notification 25.11.2025 Production problem Rivastigmine Aurobindo 6 mg hard capsules Prasugrel Change notification 25.11.2025 Production problem Prasugrel PUREN 5 mg film-coated tablets Nevirapine Change notification 25.11.2025 Other Nevirapine Aurobindo 400 mg prolonged-release tablets Flucloxacillin sodium 1 H<2>O Change notification 25.11.2025 Production problem Staphylex 250 mg capsules Moxifloxacin hydrochloride (Ph.Eur.) ((with information on water content (1:x))) Change notification 25.11.2025 Other Moxifloxacin Holsten 400 mg film-coated tablets Oxazepam Change notification 25.11.2025 Other Oxazepam AL 10 Methylphenidate hydrochloride Change notification 25.11.2025 Other Metiphenal 10 mg modified-release hard capsules Mannitol (Ph.Eur.) Initial report 25.11.2025 Other Bronchitol 40 mg hard capsule with powder for inhalation – OP10(1×10) Alprazolam Initial report 25.11.2025 Other Alprazolam – 1 A Pharma 0.5 mg tablets Gabapentin Change notification 25.11.2025 Other Gabapentin Holsten 100 mg hard capsules Oxycodone hydrochloride Change notification 24.11.2025 Other OXYGESIC 10 mg Olipudase alfa Initial report 24.11.2025 Production problem Xenpozyme Benzylpenicillin benzathine tetrahydrate (Ph.Eur.) ((with information on the dispersing or suspending agent)) Initial report 24.11.2025 Production problem Tardocillin 1200 Benperidol Initial report 24.11.2025 Production problem Glianimon 2 ml Mivacurium chloride Initial report 24.11.2025 Production problem Mivacron 20mg Pregabalin Change notification 24.11.2025 Other Pregabalin PUREN 100 mg hard capsules Quetiapine fumarate (Ph.Eur.) Change notification 24.11.2025 Production problem Quetiapine – 1 A Pharma 150 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 24.11.2025 Production problem Quetiapine HEXAL 150 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 24.11.2025 Production problem Quetiapine HEXAL 50 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 24.11.2025 Production problem Quetiapine HEXAL 400 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 24.11.2025 Production problem Quetiapine – 1 A Pharma 300 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 24.11.2025 Production problem Quetiapine – 1 A Pharma 400 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 24.11.2025 Production problem Quetiapine – 1 A Pharma 50 mg prolonged-release tablets Salbutamol sulfate Change notification 24.11.2025 Other Bronchospray novo Quetiapine fumarate (Ph.Eur.) Change notification 24.11.2025 Production problem Quetiapine – 1 A Pharma 600 mg prolonged-release tablets Cefaclor monohydrate Change notification 24.11.2025 Other Cefaclor 125 TS – 1 A Pharma Progesterone Change notification 24.11.2025 Production problem LUTINUS 100 mg vaginal tablets Tinzaparin sodium Initial report 24.11.2025 Production problem innohep 4,500 Anti-Xa I.E. Solution for injection Vancomycin hydrochloride Change notification 24.11.2025 Other Vancomycin “Lederle” 1000mg - 2025.12.01
Active ingredients Status Update Specialty trientine (dihydrochloride) Supply tension 28/11/2025 Cufence 200 mg, capsule desmopressin acetate trihydrate Stock shortage 28/11/2025 Octim 150 micrograms/dose, nasal spray solution cyamemazine Stock shortage 28/11/2025 Tercian 50 mg/5 mL, injectable solution in ampoule adrenaline Return to availability 28/11/2025 Epipen, injectable solution in a pre-filled pen phenylephrine Stock shortage 28/11/2025 Neosynephrine 10% Faure, eye drops in single-dose container methylphenidate (hydrochloride) Stock shortage 27/11/2025 Concerta LP, extended-release tablet bromfenac sodium sesquihydrate Supply tension 27/11/2025 Yellox 0.9 mg/mL, eye drops, solution methylphenidate (hydrochloride) Supply tension 27/11/2025 Biogaran Methylphenidate, extended-release tablet ritonavir Return to availability 27/11/2025 Ritonavir Arrow 100 mg, film-coated tablet betamethasone (dipropionate), betamethasone (sodium phosphate) Return to availability 27/11/2025 Diprostene, injectable suspension in pre-filled syringe tolvaptan Stock shortage 27/11/2025 Tolvaptan Teva 15 mg tablet + Tolvaptan Teva 45 mg tablet mesalazine Stock shortage 26/11/2025 Fivasa 400 mg, gastro-resistant coated tablet Normal human immunoglobulin (IgG) Supply tension 26/11/2025 Normal human immunoglobulin IV and SC (based on) dipotassium clorazepate Stock shortage 26/11/2025 Tranxene 20 mg/2 mL, lyophilisate and solution for parenteral use isoniazid, rifampicin Supply tension 26/11/2025 Rifinah 300 mg/150 mg, coated tablet isoniazid, pyrazinamid, rifampicin Supply tension 26/11/2025 Rifater, coated tablet rifampicin Supply tension 26/11/2025 Rifadine 300 mg, capsule rifampicin Return to availability 26/11/2025 Rifadine IV 600 mg, powder and solvent for solution for infusion iron (in the form of ferrous sulfate heptahydrate) Supply tension 24/11/2025 AP-HP Iron 2.5 mg infant capsule – rifamycin sodium Supply tension 24/11/2025 Rifamycin Chibret 1,000,000 IU per cent, eye drops solution - 2025.12.01
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated phenytoin sodium Injection, solution 250 mg Current Unavailable Manufacturing 28/11/2025 phenytoin sodium Injection, solution 100 mg Current Unavailable Manufacturing 28/11/2025 codeine phosphate hemihydrate Oral Liquid, solution 5 mg/mL Current Unavailable Manufacturing 28/11/2025 topiramate Tablet, film coated 25 mg Current Unavailable Manufacturing 28/11/2025 midazolam Injection, solution 5 mg/mL Current Limited Availability Manufacturing 28/11/2025 metformin hydrochloride Tablet, film coated 500 mg Resolved Available Manufacturing 28/11/2025 olanzapine Tablet, film coated 5 mg Current Unavailable Manufacturing 28/11/2025 olanzapine Tablet, film coated 7.5 mg Current Unavailable Manufacturing 28/11/2025 donepezil hydrochloride Tablet, film coated 5 mg Anticipated Available Manufacturing 28/11/2025 lamivudine Tablet, film coated 300 mg Anticipated Available Manufacturing 28/11/2025 levetiracetam Tablet, film coated 1000 mg Resolved Available Manufacturing 28/11/2025 sildenafil citrate Tablet, film coated 140.45 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 28/11/2025 ondansetron hydrochloride dihydrate Tablet, film coated 9.972 mg Current Limited Availability Manufacturing 28/11/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Resolved Available Manufacturing 28/11/2025 indapamide hemihydrate Tablet, sugar coated 2.5 mg Current Unavailable Manufacturing 28/11/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 28/11/2025 montelukast sodium Tablet, film coated 10.4 mg Anticipated Available Manufacturing 28/11/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 28/11/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 28/11/2025 finasteride Tablet, film coated 1 mg Resolved Available Manufacturing 28/11/2025 nystatin Oral Liquid, suspension 100000 IU/mL Resolved Available Unexpected increase in consumer demand 28/11/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 28/11/2025 ezetimibe Tablet, uncoated 10 mg Resolved Available Unexpected increase in consumer demand 28/11/2025 ezetimibe Tablet, uncoated 10 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 28/11/2025 lamotrigine Tablet, uncoated 25 mg Current Limited Availability Commercial Changes / Commercial viability 28/11/2025 cyproterone acetate Tablet, uncoated 100 mg Anticipated Available Manufacturing 28/11/2025 tobramycin Inhalation, conventional 60 mg/mL Anticipated Available Manufacturing 28/11/2025 nizatidine Capsule, hard 150 mg Resolved Available Manufacturing 28/11/2025 Semaglutide Injection, solution 1.34 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 28/11/2025 prasugrel Tablet, film coated 5 mg Current Unavailable Commercial Changes / Commercial viability 28/11/2025 lanreotide acetate Injection, solution 100 mg Anticipated Available Manufacturing 28/11/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 28/11/2025 naltrexone hydrochloride Tablet, film coated 50 mg Anticipated Available Manufacturing 28/11/2025 levothyroxine sodium Tablet 200 microgram Resolved Available Unexpected increase in consumer demand 28/11/2025 atracurium besilate Injection, solution 10 mg/mL Anticipated Available Manufacturing 28/11/2025 mivacurium chloride Injection, solution 2.14 mg/mL Current Unavailable Manufacturing 28/11/2025 framycetin sulfate~gramicidin~dexamethasone Ear Drops 5 mg/mL~.05 mg/mL~.5 mg/mL Anticipated Available Manufacturing 28/11/2025 phenytoin sodium Injection, solution 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 28/11/2025 phenytoin sodium Injection, solution 250 mg Current Limited Availability Manufacturing 28/11/2025 cisatracurium besilate Injection, solution 6.7 mg/mL Anticipated Available Manufacturing 28/11/2025 naratriptan hydrochloride Tablet, film coated 2.78 mg Current Limited Availability Manufacturing 28/11/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated 1 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 28/11/2025 valaciclovir hydrochloride Tablet, film coated 1112 mg Resolved Available Manufacturing 28/11/2025 risperidone Injection, modified release 50 mg Resolved Available Manufacturing 28/11/2025 verapamil hydrochloride Tablet, modified release 240 mg Resolved Available Manufacturing 27/11/2025 glimepiride Tablet, uncoated 2 mg Anticipated Available Manufacturing 27/11/2025 acetazolamide sodium Injection, powder for 549.5 mg Current Unavailable Manufacturing 27/11/2025 pentetic acid Injection, powder for 5 mg Current Unavailable Manufacturing 27/11/2025 lamotrigine Tablet, chewable 100 mg Current Limited Availability Manufacturing 27/11/2025 risperidone Tablet, film coated 2 mg Current Limited Availability Manufacturing 27/11/2025 methylphenidate hydrochloride Capsule, modified release 10 mg Resolved Available Manufacturing 27/11/2025 bisoprolol fumarate Tablet 2.5 mg Current Unavailable Manufacturing 27/11/2025 bisoprolol fumarate Tablet 10 mg Current Limited Availability Manufacturing 27/11/2025 levetiracetam Tablet, film coated 500 mg Current Limited Availability Manufacturing 27/11/2025 ropivacaine hydrochloride Injection, solution 2 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 27/11/2025 ropivacaine hydrochloride Injection, solution 7.5 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 27/11/2025 cobicistat~atazanavir Tablet, film coated 150 mg~300 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 27/11/2025 methylphenidate hydrochloride Capsule, modified release 60 mg Current Limited Availability Manufacturing 27/11/2025 risperidone Tablet, film coated 1 mg Anticipated Available Manufacturing 27/11/2025 risperidone Tablet, film coated 2 mg Anticipated Available Manufacturing 27/11/2025 letrozole Tablet, film coated 2.5 mg Resolved Available Manufacturing 27/11/2025 paclitaxel Injection, powder for 100 mg Current Limited Availability Manufacturing 27/11/2025 methylphenidate hydrochloride Capsule, hard 40 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 27/11/2025 methylphenidate hydrochloride Capsule, hard 20 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 27/11/2025 methylphenidate hydrochloride Capsule, hard 30 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 27/11/2025 methylphenidate hydrochloride Capsule, hard 10 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 27/11/2025 methylphenidate hydrochloride Capsule, hard 60 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 27/11/2025 methylphenidate hydrochloride Capsule, modified release 40 mg Current Unavailable Manufacturing 27/11/2025 lamotrigine Tablet, dispersible 100 mg Current Limited Availability Manufacturing 27/11/2025 lamotrigine Tablet, dispersible 200 mg Current Unavailable Manufacturing 27/11/2025 verapamil hydrochloride Tablet, film coated 240 mg Current Limited Availability Manufacturing 26/11/2025 valaciclovir Tablet, film coated 500 mg Current Limited Availability Manufacturing 26/11/2025 sodium pyrophosphate Injection, powder for 30 mg Current Unavailable Manufacturing 26/11/2025 risperidone Tablet 1 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 26/11/2025 losartan potassium Tablet, film coated 50 mg Current Unavailable Manufacturing 26/11/2025 losartan potassium Tablet, film coated 25 mg Current Unavailable Manufacturing 26/11/2025 mycophenolate mofetil Tablet, film coated 500 mg Current Limited Availability Manufacturing 26/11/2025 nystatin Oral Liquid 100000 IU/mL Resolved Available Commercial Changes / Commercial viability 26/11/2025 letrozole Tablet, film coated 2.5 mg Current Unavailable Manufacturing 26/11/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Current Unavailable Manufacturing 26/11/2025 amlodipine besilate~atorvastatin calcium trihydrate Tablet, film coated 13.88 mg~10.844 mg Resolved Available Manufacturing 26/11/2025 midazolam Injection, solution 50 mg Current Unavailable Manufacturing 26/11/2025 flecainide acetate Tablet, uncoated 50 mg Current Limited Availability Manufacturing 26/11/2025 rosuvastatin calcium Tablet, film coated 20.84 mg Current Unavailable Unexpected increase in consumer demand 26/11/2025 pregabalin Capsule, hard 150 mg Current Limited Availability Unexpected increase in consumer demand 26/11/2025 pregabalin Capsule, hard 25 mg Resolved Available Manufacturing 26/11/2025 levetiracetam Solution 100 mg/mL Current Limited Availability Manufacturing 26/11/2025 atomoxetine hydrochloride Capsule, hard 20.57 mg Current Unavailable Manufacturing 26/11/2025 dabigatran etexilate mesilate Capsule, hard 172.95 mg Current Unavailable Manufacturing 26/11/2025 metaraminol tartrate Injection, solution 19 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 26/11/2025 tamoxifen citrate Tablet 30.34 mg Anticipated Available Manufacturing 26/11/2025 sunitinib Capsule 12.5 mg Anticipated Available Manufacturing 26/11/2025 tofacitinib citrate Solution 1.62 mg/mL Anticipated Available Manufacturing 26/11/2025 risperidone Oral Liquid, solution 1 mg/mL Current Unavailable Manufacturing 26/11/2025 ropivacaine hydrochloride Injection, solution 2 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 26/11/2025 vinorelbine tartrate Injection, concentrated 13.85 mg/mL Discontinued Unavailable Commercial Changes / Commercial viability 26/11/2025 vinorelbine tartrate Injection, concentrated 13.85 mg/mL Discontinued Unavailable Commercial Changes / Commercial viability 26/11/2025 clonidine hydrochloride Tablet, uncoated 150 microgram Anticipated Available Manufacturing 26/11/2025 methylphenidate hydrochloride Capsule, modified release 20 mg Current Limited Availability Manufacturing 26/11/2025 methylphenidate hydrochloride Capsule, modified release 30 mg Current Limited Availability Manufacturing 26/11/2025 flecainide acetate Injection, solution 10 mg/mL Resolved Available Transport / Logistic issues / Storage capacity issues 25/11/2025 lidocaine hydrochloride Gel 20 mg/g Resolved Available Manufacturing 25/11/2025 medronic acid Injection, powder for 10 mg Current Unavailable Manufacturing 25/11/2025 sodium fluoride Injection, concentrated 1 mg/mL Current Unavailable Manufacturing 25/11/2025 phenoxymethylpenicillin potassium Tablet, film coated 560 mg Resolved Available Manufacturing 25/11/2025 armodafinil Tablet, uncoated 150 mg Anticipated Available Transport / Logistic issues / Storage capacity issues 25/11/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Unexpected increase in consumer demand 25/11/2025 enalapril maleate Tablet 5 mg Anticipated Available Manufacturing 24/11/2025 phenobarbital Tablet, uncoated 30 mg Current Unavailable Manufacturing 24/11/2025 hydrochlorothiazide~candesartan cilexetil Tablet, uncoated 12.5 mg~16 mg Anticipated Available Manufacturing 24/11/2025 lansoprazole Tablet, orally disintegrating 15 mg Current Unavailable Manufacturing 24/11/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Unavailable Manufacturing 24/11/2025 tranexamic acid Tablet, film coated 500 mg Current Unavailable Manufacturing 24/11/2025 nizatidine Capsule, hard 150 mg Current Unavailable Manufacturing 24/11/2025 metformin hydrochloride Tablet, film coated 1000 mg Resolved Available Unexpected increase in consumer demand 24/11/2025 ondansetron hydrochloride dihydrate Tablet, film coated 9.972 mg Anticipated Available Manufacturing 24/11/2025 fenofibrate Tablet, film coated 145 mg Anticipated Available Manufacturing 24/11/2025 escitalopram oxalate Tablet, film coated 12.74 mg Resolved Available Commercial Changes / Commercial viability 24/11/2025 escitalopram oxalate Tablet, film coated 25.47 mg Resolved Available Manufacturing 24/11/2025 eplerenone Tablet, film coated 25 mg Current Limited Availability Manufacturing 24/11/2025 Rabies virus Injection, powder for 2.5 IU Resolved Available Unexpected increase in consumer demand 24/11/2025 metaraminol tartrate Injection, solution 19 mg Current Unavailable Manufacturing 24/11/2025 Tocilizumab Injection, solution 162 mg Resolved Available Manufacturing 24/11/2025 lanreotide acetate Injection, solution 66.67 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 24/11/2025 hydrocortisone hydrogen succinate Injection, powder for 127.6 mg Current Limited Availability Manufacturing 24/11/2025 mupirocin Ointment 20 mg/g Current Unavailable Manufacturing 24/11/2025 labetalol hydrochloride Tablet, film coated 100 mg Current Unavailable Manufacturing 24/11/2025 flunitrazepam Tablet, film coated 1 mg Current Limited Availability Manufacturing 24/11/2025 ciprofloxacin hydrochloride Tablet, film coated 582.21 mg Anticipated Available Manufacturing 24/11/2025 nizatidine Capsule, hard 300 mg Current Limited Availability Manufacturing 24/11/2025 - 2025.12.01
Generic Name Shortage Status Revision Date Acetazolamide Injection Current Shortages 26-Nov-25 Adenosine Injection Current Shortages 26-Nov-25 Albuterol sulfate and Ipratropium Bromide Inhalation Solution Current Shortages 26-Nov-25 Diazepam Injection Current Shortages 26-Nov-25 Dipyridamole Injection Current Shortages 26-Nov-25 Eptifibatide Injection Current Shortages 26-Nov-25 Etomidate Injection Current Shortages 26-Nov-25 Fludarabine Injection Current Shortages 26-Nov-25 Hydroxyethyl Starch (Hetastarch) Current Shortages 26-Nov-25 Minoxidil 2.5 mg Tablets Resolved Shortages 26-Nov-25 Prednisone Oral Tablets Current Shortages 26-Nov-25 Imatinib Mesylate Tablets Current Shortages 25-Nov-25 Insulin Premixed Solution for Injection (Myxredlin) Current Shortages 25-Nov-25 Leucovorin Calcium Tablets Current Shortages 25-Nov-25 Lanreotide Acetate Injection Current Shortages 24-Nov-25 Lisdexamfetamine Dimesylate Capsules Current Shortages 24-Nov-25 - 2025.12.01
New
この間、新しい不足情報は公開されていません。
Updated
この間、更新された不足情報は公開されていません。
2025年11月
- 2025.11.25
Medicine supply notification: Ibandronic acid 150mg tablets
イバンドロン酸150mg錠剤(唯一の認可済み月用ビスホスホネート)は2026年3月まで限定的に供給されています。アレンドロン酸70mg錠剤およびリセドロン酸ナトリウム35mg錠剤(週1回のビスホスホネート投与)は引き続き入手可能で、需要の増加を支えることができます
- 2025.11.24
Active ingredients Message type Date of last message Type of reason AM designation Levothyroxine sodium Initial report 21.11.2025 Production problem L-thyroxine Aventis 150 microgram tablets Levothyroxine sodium Change notification 21.11.2025 Production problem L-Thyroxine Henning 50 Sevelamer carbonate Change notification 21.11.2025 Other Renvela 0.8 g powder for oral suspension – OP(90×842.32mg) Rizatriptan benzoate Change notification 21.11.2025 Production problem Rizatriptan Glenmark 5 mg orodispersible tablets Moxifloxacin hydrochloride (Ph.Eur.) ((with information on water content (1:x))) Initial report 20.11.2025 Other Moxifloxacin Micro Labs 400 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 20.11.2025 Other Atorvastatin Micro Labs 60 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Initial report 20.11.2025 Other Atorvastatin Micro Labs 40 mg film-coated tablets Sunitinib Initial report 20.11.2025 Other Sunitinib AL 37.5 mg hard capsules Sunitinib Initial report 20.11.2025 Other Sunitinib AL 12.5 mg hard capsules Atorvastatin calcium trihydrate (Ph.Eur.) Initial report 20.11.2025 Other Atorvastatin Micro Labs 30 mg film-coated tablets Isoniazid Initial report 20.11.2025 Other Isozid 100 mg Diazepam Initial report 20.11.2025 Other Diazepam-ratiopharm 10 mg/2 ml solution for injection Rifampicin sodium Initial report 20.11.2025 Other Eremfat i.v. 300mg Alprazolam Initial report 20.11.2025 Other Alprazolam AbZ 0.5 mg tablets Alprazolam Initial report 20.11.2025 Other Alprazolam-ratiopharm 0.5 mg tablets Trandolapril; verapamil hydrochloride Change notification 20.11.2025 Other Tarka 180 mg/2 mg modified-release tablets Morphine hemisulfate 2.5 hydrate Initial report 19.11.2025 Production problem Substitol 30 mg hard capsules, delayed release Hydromorphone hydrochloride Change notification 19.11.2025 Production problem Palladon injection 2 mg Aprepitant Change notification 19.11.2025 Other Aprepitant AL 125 mg and 80 mg hard capsules Quetiapine fumarate (Ph.Eur.) Change notification 19.11.2025 Other Quetiapine AL 300 mg film-coated tablets Beclomethasone dipropionate (Ph.Eur.) Change notification 19.11.2025 Other Beclorhinol aquosum 50 micrograms Nitrendipine Change notification 19.11.2025 Other Nitrendipine AL 20 Vinflunine bis[(R,R)-tartrate] Change notification 18.11.2025 Production problem Javlor 25 mg/ml concentrate for solution for infusion – OP(1x2ml) Chlortalidone Change notification 18.11.2025 Other Chlortalidone HEXAL 12.5 mg tablets Calcium trisodium pentetate (with information on water content, if applicable) Change notification 18.11.2025 Other Technescan DTPA Medium-chain triglycerides; omega-3 acid triglycerides (with information on origin and/or composition); refined soybean oil (Ph.Eur.) Change notification 18.11.2025 Production problem Lipidem Emulsion for infusion Aprepitant Change notification 18.11.2025 Production problem Aprepitant STADA 125 mg and 80 mg hard capsules Aprepitant Change notification 18.11.2025 Production problem Aprepitant STADA 80 mg hard capsules Aprepitant Change notification 18.11.2025 Production problem Aprepitant STADA 125 mg hard capsules Misoprostol Change notification 17.11.2025 Other Angusta 25 microgram tablets Insulin glargine Initial report 17.11.2025 Other ABASAGLAR 100 IU/ml solution for injection in pre-filled pen – OP (5x3ml) Posaconazole Change notification 17.11.2025 Other Posaconazole HEXAL 40 mg/ml oral suspension Lidocaine hydrochloride monohydrate Change notification 17.11.2025 Other Xylocaine Gel 2% Vancomycin hydrochloride Change notification 17.11.2025 Other Vancomycin “Lederle” 1000mg - 2025.11.24
Active ingredients Status Update Specialty olanzapine (pamoate) monohydrate Supply tension 21/11/2025 Zypadhera, powder and solvent for extended-release suspension for injection risperidone Supply tension 21/11/2025 Risperidone 0.5 mg, orodispersible tablet risperidone Stock shortage 21/11/2025 Risperidone 4 mg orodispersible tablet risperidone Stock shortage 21/11/2025 Risperidone 3 mg orodispersible tablet risperidone Return to availability 21/11/2025 Risperidone 1 mg and 2 mg, orodispersible tablet chlorpromazine (hydrochloride) Stock shortage 20/11/2025 Largactil 100 mg, film-coated tablet phenylephrine Stock shortage 19/11/2025 Neosynephrine 10% Faure, eye drops in single-dose container phenylephrine Supply tension 19/11/2025 Neosynephrine 10% Faure, eye drops solution phenylephrine Supply tension 19/11/2025 Neosynephrine 5% Faure, eye drops solution methylphenidate (hydrochloride) Supply tension 19/11/2025 Methylphenidate EG LP, extended-release tablet ornidazole Stock shortage 18/11/2025 Tiberal 1 g, solution for injection for infusion colchicine, opium (powder), tiemonium (methyl sulfate) Supply tension 18/11/2025 Colchimax, breakable film-coated tablet, and Colchicine Opocalcium 1 mg, breakable tablet lenalidomide Stock shortage 18/11/2025 Lenalidomide Mylan, capsule adrenaline (tartrate) Return to availability 17/11/2025 Jext 300 micrograms, injectable solution in pre-filled pen - 2025.11.24
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated primidone Tablet, uncoated 250 mg Resolved Available Manufacturing 21/11/2025 trandolapril Capsule 2 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 21/11/2025 olanzapine pamoate monohydrate Injection, powder for 690 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 21/11/2025 nortriptyline Tablet, film coated 10 mg Anticipated Available Manufacturing 21/11/2025 lamotrigine Tablet, chewable 50 mg Current Unavailable Manufacturing 21/11/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 21/11/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 21/11/2025 ondansetron hydrochloride dihydrate Tablet, film coated 4.986 mg Anticipated Available Manufacturing 21/11/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 21/11/2025 lansoprazole Tablet, orally disintegrating 15 mg Current Limited Availability Unexpected increase in consumer demand 21/11/2025 quetiapine fumarate Tablet, modified release 345.39 mg Current Limited Availability Manufacturing 21/11/2025 quetiapine fumarate Tablet, modified release 460.52 mg Current Limited Availability Manufacturing 21/11/2025 quetiapine fumarate Tablet, modified release 345.39 mg Current Limited Availability Manufacturing 21/11/2025 mesalazine Granules, modified release 4 g Resolved Available Transport / Logistic issues / Storage capacity issues 21/11/2025 olmesartan medoxomil~hydrochlorothiazide Tablet 20 mg~12.5 mg Current Limited Availability Manufacturing 21/11/2025 acamprosate calcium Tablet, enteric coated 333 mg Anticipated Available Manufacturing 21/11/2025 latanoprost Eye Drops, solution .05 mg/mL Current Limited Availability Manufacturing 21/11/2025 latanoprost Eye Drops, solution .05 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 21/11/2025 benzathine benzylpenicillin tetrahydrate Injection, suspension 600000 USP Unit Current Unavailable Manufacturing 21/11/2025 ropinirole hydrochloride Tablet, film coated .285 mg Current Unavailable Manufacturing 21/11/2025 paroxetine hydrochloride Tablet, film coated 22.22 mg Anticipated Available Manufacturing 21/11/2025 lamotrigine Tablet, chewable 50 mg Current Limited Availability Manufacturing 21/11/2025 lamotrigine Tablet, chewable 100 mg Current Unavailable Manufacturing 21/11/2025 lamotrigine Tablet, chewable 200 mg Current Unavailable Manufacturing 21/11/2025 lamotrigine Tablet, chewable 200 mg Anticipated Available Manufacturing 21/11/2025 betahistine dihydrochloride Tablet 16 mg Current Limited Availability Manufacturing 21/11/2025 ondansetron hydrochloride dihydrate Tablet, film coated 4.986 mg Anticipated Available Manufacturing 21/11/2025 Alteplase Diluent, not applicable 10 mg Current Limited Availability Unexpected increase in consumer demand 21/11/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated .125 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 21/11/2025 desferrioxamine mesilate Injection, powder for 2 g Anticipated Available Manufacturing 21/11/2025 linezolid Injection, solution 2 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 21/11/2025 ciprofloxacin hydrochloride Tablet, film coated 873.32 mg Current Unavailable Manufacturing 21/11/2025 lamotrigine Tablet, dispersible 100 mg Current Limited Availability Manufacturing 21/11/2025 rifampicin Oral Liquid 20 mg/mL Anticipated Available Unexpected increase in consumer demand 20/11/2025 imipramine hydrochloride Tablet, sugar coated 10 mg Anticipated Available Manufacturing 20/11/2025 lidocaine hydrochloride Gel 20 mg/g Current Limited Availability Manufacturing 20/11/2025 benzathine benzylpenicillin tetrahydrate Injection, suspension 1200000 USP Unit Current Emergency Supply Only Manufacturing 20/11/2025 ondansetron hydrochloride dihydrate Injection, solution 10 mg Current Limited Availability Manufacturing 20/11/2025 galantamine hydrobromide Capsule, modified release 20.512 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 20/11/2025 galantamine hydrobromide Capsule, modified release 30.768 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 20/11/2025 temozolomide Capsule, hard 5 mg Current Limited Availability Manufacturing 20/11/2025 Alteplase Injection, powder for 50 mg Resolved Available Unexpected increase in consumer demand 20/11/2025 tobramycin Capsule, hard 28 mg Current Emergency Supply Only Manufacturing 20/11/2025 desvenlafaxine Tablet, modified release 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 20/11/2025 desvenlafaxine Tablet, modified release 50 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 20/11/2025 entecavir Tablet, film coated .5 mg Current Unavailable Manufacturing 20/11/2025 entecavir Tablet, film coated 1 mg Current Limited Availability Manufacturing 20/11/2025 armodafinil Tablet, uncoated 250 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 20/11/2025 rifampicin Capsule 150 mg Current Emergency Supply Only Manufacturing 20/11/2025 rifampicin Capsule 300 mg Current Limited Availability Manufacturing 20/11/2025 atomoxetine hydrochloride Capsule, hard 20.57 mg Anticipated Available Manufacturing 20/11/2025 hydroxocobalamin acetate Injection, solution 1.044 mg Anticipated Available Unexpected increase in consumer demand 20/11/2025 doxepin hydrochloride Capsule, hard 11.3 mg Current Limited Availability Manufacturing 20/11/2025 levodopa~carbidopa monohydrate Tablet, uncoated 100 mg~27 mg Resolved Available Manufacturing 20/11/2025 deferasirox Tablet, film coated 90 mg Current Limited Availability Manufacturing 20/11/2025 deferasirox Tablet, film coated 360 mg Current Unavailable Manufacturing 20/11/2025 escitalopram oxalate Tablet, film coated 25.548 mg Current Limited Availability Manufacturing 20/11/2025 ropivacaine hydrochloride Injection, solution 7.5 mg/mL Current Limited Availability Manufacturing 20/11/2025 ropivacaine hydrochloride Injection, solution 7.5 mg/mL Current Unavailable Manufacturing 20/11/2025 ropivacaine hydrochloride Injection, solution 2 mg/mL Anticipated Available Manufacturing 20/11/2025 olanzapine Tablet, film coated 5 mg Resolved Available Transport / Logistic issues / Storage capacity issues 20/11/2025 dosulepin hydrochloride Tablet, film coated 75 mg Current Limited Availability Manufacturing 20/11/2025 olanzapine Wafer 5 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 20/11/2025 risperidone Injection, modified release 50 mg Current Limited Availability Manufacturing 20/11/2025 nizatidine Capsule 300 mg Current Limited Availability Manufacturing 20/11/2025 perindopril erbumine~indapamide hemihydrate Tablet, uncoated 4 mg~1.25 mg Discontinued Unavailable Commercial Changes / Commercial viability 20/11/2025 sertraline hydrochloride Tablet, film coated 55.96 mg Resolved Available Manufacturing 19/11/2025 minoxidil Tablet, uncoated 10 mg Current Limited Availability Manufacturing 19/11/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Manufacturing 19/11/2025 pregabalin Capsule, hard 25 mg Current Limited Availability Manufacturing 19/11/2025 hydrochlorothiazide~olmesartan medoxomil Tablet 12.5 mg~40 mg Current Limited Availability Manufacturing 19/11/2025 sacubitril~valsartan Tablet, film coated 97.2 mg~102.8 mg Current Unavailable Manufacturing 19/11/2025 tetrabenazine Tablet, uncoated 25 mg Current Unavailable Manufacturing 19/11/2025 chlorhexidine gluconate~cetrimide Solution, irrigation 15 mg~150 mg Anticipated Available Manufacturing 19/11/2025 chlorhexidine gluconate~cetrimide Solution, irrigation 4.5 mg~45 mg Anticipated Available Manufacturing 19/11/2025 betiatide Injection, powder for 1 mg Current Unavailable Manufacturing 18/11/2025 phenytoin sodium Injection, solution 250 mg Current Limited Availability Manufacturing 18/11/2025 phenytoin sodium Injection, solution 100 mg Current Unavailable Manufacturing 18/11/2025 olanzapine Tablet, orally disintegrating 5 mg Current Unavailable Manufacturing 18/11/2025 ropivacaine hydrochloride Injection, solution 2 mg/mL Discontinued Unavailable Commercial Changes / Commercial viability 18/11/2025 ropivacaine hydrochloride Injection, solution 2 mg/mL Discontinued Unavailable Commercial Changes / Commercial viability 18/11/2025 atorvastatin calcium trihydrate~amlodipine besilate Tablet, film coated 43.376 mg~6.94 mg Resolved Available Manufacturing 18/11/2025 hydromorphone hydrochloride Injection, solution 10 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 18/11/2025 Tocilizumab Injection, solution 162 mg Anticipated Available Manufacturing 18/11/2025 phenytoin sodium Injection, solution 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 18/11/2025 phenytoin sodium Injection, solution 250 mg Current Limited Availability Manufacturing 18/11/2025 dinoprostone Gel .3333 mg/g Current Emergency Supply Only Manufacturing 18/11/2025 dinoprostone Gel .6667 mg/g Current Emergency Supply Only Manufacturing 18/11/2025 flecainide acetate Injection, solution 10 mg/mL Current Unavailable Transport / Logistic issues / Storage capacity issues 17/11/2025 prazosin hydrochloride Tablet, uncoated 1.095 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 17/11/2025 prazosin hydrochloride Tablet, uncoated 5.476 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 17/11/2025 tobramycin Injection, solution 80 mg Anticipated Available Manufacturing 17/11/2025 mupirocin Ointment 22 mg/g Resolved Available Unexpected increase in consumer demand 17/11/2025 glimepiride Tablet, uncoated 1 mg Current Unavailable Manufacturing 17/11/2025 risperidone Tablet, film coated 3 mg Current Unavailable Manufacturing 17/11/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 17/11/2025 galantamine hydrobromide Capsule, modified release 10.252 mg Current Unavailable Manufacturing 17/11/2025 galantamine hydrobromide Capsule, modified release 10.252 mg Current Unavailable Manufacturing 17/11/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 17/11/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 17/11/2025 tranexamic acid Injection, solution 1000 mg Current Unavailable Commercial Changes / Commercial viability 17/11/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Resolved Available Manufacturing 17/11/2025 flecainide acetate Tablet, uncoated 50 mg Anticipated Available Manufacturing 17/11/2025 bimatoprost Eye Drops .3 mg/mL Current Unavailable Manufacturing 17/11/2025 anastrozole Tablet, film coated 1 mg Resolved Available Manufacturing 17/11/2025 tenofovir disoproxil maleate~efavirenz~emtricitabine Tablet, film coated 300 mg~600 mg~200 mg Current Unavailable Manufacturing 17/11/2025 escitalopram oxalate Tablet, film coated 12.74 mg Current Unavailable Commercial Changes / Commercial viability 17/11/2025 escitalopram oxalate Tablet, film coated 25.47 mg Current Limited Availability Manufacturing 17/11/2025 ambrisentan Tablet, film coated 10 mg Current Limited Availability Manufacturing 17/11/2025 risperidone Tablet, film coated 1 mg Anticipated Available Manufacturing 17/11/2025 dimethyl fumarate Capsule, enteric 240 mg Anticipated Available Manufacturing 17/11/2025 fingolimod hydrochloride Capsule 560 microgram Current Limited Availability Manufacturing 17/11/2025 oseltamivir phosphate Capsule, hard 98.524 mg Current Limited Availability Manufacturing 17/11/2025 lamotrigine Tablet, chewable 100 mg Current Unavailable Manufacturing 17/11/2025 rivaroxaban Tablet, film coated 10 mg Resolved Available Manufacturing 17/11/2025 rivaroxaban Tablet, film coated 15 mg Current Limited Availability Manufacturing 17/11/2025 sitagliptin hydrochloride monohydrate~metformin hydrochloride Tablet, modified release 56.685 mg~1000 mg Current Unavailable Manufacturing 17/11/2025 nitrofurantoin Capsule, hard 50 mg Anticipated Available Manufacturing 17/11/2025 patisiran sodium Injection, concentrated 10.5 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 17/11/2025 bleomycin sulfate Injection, powder for 15000 IU Current Emergency Supply Only Manufacturing 17/11/2025 bumetanide Tablet, uncoated 1 mg Resolved Available Manufacturing 17/11/2025 ethinylestradiol~norethisterone Tablet, uncoated 36 microgram~500 microgram Current Limited Availability Manufacturing 17/11/2025 voriconazole Injection, powder for 200 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 17/11/2025 galantamine hydrobromide~galantamine Capsule, modified release 20.51 mg~16 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 17/11/2025 - 2025.11.24
Generic Name Shortage Status Revision Date Amoxicillin Oral Presentations Current Shortages 21-Nov-25 Dextroamphetamine Extended-Release Capsules Current Shortages 21-Nov-25 Lanthanum Carbonate Oral Presentations Current Shortages 21-Nov-25 Liraglutide Injection Current Shortages 21-Nov-25 Lorazepam Tablets Current Shortages 21-Nov-25 Oxacillin Sodium Injection Current Shortages 21-Nov-25 Bivalirudin Injection Current Shortages 20-Nov-25 Epinephrine Auto-Injectors Current Shortages 20-Nov-25 Haloperidol Lactate Injection Current Shortages 20-Nov-25 Cromolyn Oral Solution Current Shortages 19-Nov-25 Mercaptopurine Tablets Current Shortages 19-Nov-25 Carboplatin Solution for Injection Current Shortages 18-Nov-25 Dronabinol Capsules Current Shortages 18-Nov-25 Erythromycin Lactobionate Injection Current Shortages 18-Nov-25 Potassium Chloride Injection Current Shortages 18-Nov-25 Quinapril Tablets Current Shortages 18-Nov-25 Sterile Water for Irrigation Current Shortages 18-Nov-25 Succinylcholine Injection Current Shortages 18-Nov-25 50% Dextrose Injection Resolved Shortages 17-Nov-25 Ascorbic Acid Injection Current Shortages 17-Nov-25 Budesonide Suspension for Inhalation Current Shortages 17-Nov-25 Chlorothiazide Oral Suspension Current Shortages 17-Nov-25 Cisplatin Injection Current Shortages 17-Nov-25 Clindamycin Phosphate Injection Current Shortages 17-Nov-25 Dimenhydrinate Injection Current Shortages 17-Nov-25 Rocuronium Injection Current Shortages 17-Nov-25 Ropivacaine Injection Current Shortages 17-Nov-25 Triamcinolone Hexacetonide Injection Current Shortages 17-Nov-25 - 2025.11.24
New
November 21, 2025
- Potassium Chloride Tablet, Extended Release (Discontinuation)
- Verapamil Hydrochloride Injection (Discontinuation)
November 19, 2025
- Anagrelide Hydrochloride Capsule (Discontinuation)
- Hydrochlorothiazide Capsule (Discontinuation)
- Valsartan Tablet (Discontinuation)
November 17, 2025
- Montelukast Sodium Tablet, Chewable (Discontinuation)
Updated
November 20, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Carboplatin Injection (Currently in Shortage)
- Heparin Sodium Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Nitroglycerin Injection (Currently in Shortage)
- Streptozocin Powder, For Solution (Currently in Shortage)
November 19, 2025
- Epinephrine Bitartrate, Lidocaine Hydrochloride Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
November 18, 2025
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Metronidazole Injection (Discontinuation)
November 17, 2025
- Flurazepam Hydrochloride Capsule (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- 2025.11.18
Medicine supply notification: Propranolol 80mg and 160mg modified release capsules
プロプラノロール80mgのM/Rカプセルは2026年3月初旬まで在庫切れ、160mgのM/Rカプセルは2026年11月下旬から1月中旬から下旬まで在庫切れです。I/Rの40mgおよび80mgのタブがあり、需要の増加にも対応できます。経口用溶液は利用可能ですが、需要の増加には対応できません
- 2025.11.18
Active ingredients Message type Date of last message Type of reason AM designation Hydromorphone hydrochloride Initial report 14.11.2025 Production problem Palladon inject 2 mg Sevelamer carbonate Initial report 14.11.2025 Other Renvela 0.8 g powder for oral suspension – OP(90×842.32mg) Pirfenidone Change notification 14.11.2025 Production problem Pirfenidone Accord 801 mg film-coated tablets Dinoprostone Initial report 14.11.2025 Other Minprostin E2 vaginal gel 2 mg Dinoprostone Initial report 14.11.2025 Other Minprostin E2 vaginal gel 1 mg Sertraline hydrochloride Change notification 14.11.2025 Other Sertraline TAD 100 mg film-coated tablets Sertraline hydrochloride Change notification 14.11.2025 Other Sertraline TAD 50 mg film-coated tablets Methyldopa (Ph.Eur.) Change notification 14.11.2025 Other Dopegyt tablets Quetiapine fumarate (Ph.Eur.) Change notification 14.11.2025 Other Seroquel Prolong 150 mg prolonged-release tablets Trandolapril; verapamil hydrochloride Change notification 13.11.2025 Other Tarka 240 mg/4 mg modified-release tablets Posaconazole Change notification 13.11.2025 Other Posaconazole AL 40 mg/ml oral suspension Methylphenidate hydrochloride Change notification 13.11.2025 Other Metiphenal 10 mg modified-release hard capsules Quetiapine fumarate (Ph.Eur.) Change notification 13.11.2025 Other Quetiapine AL 150 mg prolonged-release tablets Proxymetacaine hydrochloride Initial report 12.11.2025 Production problem Proparacaine-POS 0.5% Quetiapine fumarate (Ph.Eur.) Change notification 12.11.2025 Other Seroquel Prolong 50 mg prolonged-release tablets Tamsulosin hydrochloride Initial report 12.11.2025 Other Tamsulosin hydrochloride PUREN 0.4 mg prolonged-release capsules Pregabalin Change notification 12.11.2025 Other Pregabalin Aurobindo 25 mg hard capsules Ibuprofen Initial report 12.11.2025 Production problem Ibuprofen PUREN 600 mg film-coated tablets Gabapentin Initial report 12.11.2025 Other Gabapentin Aurobindo 600 mg film-coated tablets Urapidil Initial report 12.11.2025 Other Urapidil PUREN 60 mg prolonged-release capsules Urapidil Initial report 12.11.2025 Other Urapidil PUREN 30 mg prolonged-release capsules Fentanyl Change notification 12.11.2025 Production problem Fentanyl PUREN 25 micrograms/h transdermal patch Lamotrigine Initial report 12.11.2025 Production problem Lamotrigine Aurobindo 5 mg tablets for oral suspension Rizatriptan benzoate Change notification 12.11.2025 Production problem Rizatriptan PUREN 5 mg tablets Sitagliptin hydrochloride monohydrate Initial report 12.11.2025 Other Sitagliptin PUREN 25 mg film-coated tablets Gemcitabine hydrochloride Initial report 12.11.2025 Other Gemcitabine Aurobindo 40 mg/ml concentrate for solution for infusion Mesalazine Change notification 12.11.2025 Production problem Claversal Micropellets 1.5 g Risperidone Initial report 12.11.2025 Other Risperidone PUREN 3 mg film-coated tablets Risperidone Initial report 12.11.2025 Other Risperidone PUREN 0.5 mg film-coated tablets Mesalazine Initial report 12.11.2025 Other Claversal 500 mg tablets Propranolol hydrochloride Initial report 12.11.2025 Other Propranolol PUREN 10 mg film-coated tablets Buprenorphine hydrochloride Initial report 12.11.2025 Other Buprenorphine PUREN 8 mg sublingual tablets Oxycodone hydrochloride (Ph.Eur.) Initial report 12.11.2025 Other Oxycodone hydrochloride Puren 10 mg prolonged-release tablets Levetiracetam Initial report 12.11.2025 Other Levetiracetam PUREN 1000 mg film-coated tablets Levetiracetam Initial report 12.11.2025 Other Levetiracetam Aurobindo 1000 mg film-coated tablets Lamotrigine Initial report 12.11.2025 Other Lamotrigine Aurobindo 25 mg tablets Efavirenz; emtricitabine; tenofovir disoproxil fumarate Initial report 12.11.2025 Other Efavirenz/emtricitabine/tenofovir disoproxil PUREN 600 mg/200 mg/245 mg film-coated tablets Linezolid Initial report 12.11.2025 Other Linezolid PUREN 600 mg film-coated tablets Risperidone Initial report 12.11.2025 Other Risperidone Aurobindo 1 mg film-coated tablets Olanzapine embonate monohydrate Initial report 11.11.2025 Production problem ZYPADHERA 405 mg powder and solvent for the preparation of a depot injection suspension – OP(931mg+3ml) Aprepitant Change notification 11.11.2025 Other Aprepitant AL 125 mg hard capsules Oxazepam Change notification 11.11.2025 Other Oxazepam AL 10 Ciprofloxacin hydrochloride (1:1) 1 H<2>O Change notification 11.11.2025 Other Ciprohexal 100 mg Ciprofloxacin hydrochloride (1:1) 1 H<2>O Change notification 11.11.2025 Other Cipro-1 A Pharma 100mg Terbutaline sulfate (Ph.Eur.) Change notification 11.11.2025 Production problem BRICANYL 0.5 mg Nimodipine Change notification 10.11.2025 Other Nimodipine Hexal 30mg Insulin lispro Initial report 10.11.2025 Other Liprolog 100 E/ml solution for injection in cartridge – OP[2x(5x3ml)] Human insulin (with manufacturing details) Initial report 10.11.2025 Other Huminsulin Normal KwikPen 100 IU/ml solution for injection Calcium trisodium pentetate (with information on water content, if applicable) Initial report 10.11.2025 Other Technescan DTPA Sevelamer Change notification 10.11.2025 Other Renagel 800 mg film-coated tablets – OP(1×180) Tenofovir disoproxil fumarate Initial report 10.11.2025 Other Tenofovir disoproxil PUREN 245 mg film-coated tablets Lidocaine Initial report 10.11.2025 Other XYLOCAIN PUMP SPRAY Vinflunine bis[(R,R)-tartrate] Initial report 10.11.2025 Production problem Javlor 25 mg/ml concentrate for solution for infusion – OP (1x2ml) Ipratropium bromide (Ph.Eur.); salbutamol sulfate Change notification 10.11.2025 Production problem Ipratropium/salbutamol Cipla 0.5 mg/2.5 mg solution for nebulizer Valsartan Initial report 10.11.2025 Production problem Valsartan STADA 80 mg film-coated tablets Valsartan Initial report 10.11.2025 Production problem Valsartan STADA 160 mg film-coated tablets Aprepitant Initial report 10.11.2025 Other EMEND 125 mg powder for oral suspension – OPXXXXmg Amikacin sulfate Change notification 10.11.2025 Production problem Amikacin B. Braun 2.5 mg/ml solution for infusion Amikacin sulfate Change notification 10.11.2025 Production problem Amikacin B. Braun 5 mg/ml solution for infusion Tolterodine tartrate Change notification 10.11.2025 Other Detrusitol 2 mg film-coated tablets Ipratropium bromide Change notification 10.11.2025 Production problem Ipratropium bromide 125 micrograms/1 ml Stulln Duloxetine hydrochloride Initial report 10.11.2025 Other Cymbalta 60 mg gastro-resistant hard capsules – OP28 - 2025.11.18
Active ingredients Status Update Specialty dopamine (hydrochloride) Supply tension 14/11/2025 Dopamine Viatris 40 mg/mL, solution for infusion dipotassium clorazepate Stock shortage 14/11/2025 Tranxene 20 mg/2 mL, lyophilisate and solution for parenteral use cyamemazine Stock shortage 14/11/2025 Tercian 50 mg/5 mL, injectable solution in ampoule temozolomide Return to availability 14/11/2025 Temodal 2.5 mg/mL, powder for solution for infusion propofol Return to availability 14/11/2025 Diprivan 20 mg/mL, injectable emulsion in pre-filled syringe propofol Return to availability 14/11/2025 Diprivan 10 mg/mL, injectable emulsion in pre-filled syringe megestrol (acetate) Stock shortage 13/11/2025 Megace 160 mg, tablet methylphenidate (hydrochloride) Supply tension 13/11/2025 Methylphenidate EG LP 18 mg and 36 mg, extended-release tablet fluorouracil Supply tension 13/11/2025 Fluorouracil Pfizer 50 mg/mL, solution for dilution for infusion – 20 mL and 100 mL vials valproic acid, sodium (valproate) Supply tension 13/11/2025 Micropakine L.P., extended-release granules in single-dose sachets tolvaptan Stock shortage 10/11/2025 Tolvaptan Biogaran 15 mg, tablet + Tolvaptan Biogaran 45 mg, tablet – tolvaptan Stock shortage 10/11/2025 Tolvaptan Teva 15 mg tablet + Tolvaptan Teva 45 mg tablet - 2025.11.18
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated atracurium besilate Injection, intravenous infusion 10 mg/mL Current Unavailable Manufacturing 14/11/2025 lamotrigine Tablet, chewable 100 mg Current Unavailable Manufacturing 14/11/2025 bisoprolol fumarate Tablet 5 mg Current Limited Availability Manufacturing 14/11/2025 bisoprolol fumarate Tablet 10 mg Current Limited Availability Manufacturing 14/11/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Current Unavailable Manufacturing 14/11/2025 atorvastatin calcium trihydrate~amlodipine besilate Tablet, film coated 43.376 mg~13.88 mg Resolved Available Manufacturing 14/11/2025 quetiapine fumarate Tablet, modified release 345.39 mg Current Limited Availability Manufacturing 14/11/2025 linezolid Tablet, film coated 600 mg Current Unavailable Manufacturing 14/11/2025 amlodipine besilate~olmesartan medoxomil Tablet, film coated 6.935 mg~20 mg Anticipated Available Manufacturing 14/11/2025 pregabalin Capsule, hard 300 mg Resolved Available Manufacturing 14/11/2025 hydrochlorothiazide~olmesartan medoxomil~amlodipine besilate Tablet, film coated 12.5 mg~40 mg~13.9 mg Current Unavailable Manufacturing 14/11/2025 lamotrigine Tablet, chewable 50 mg Anticipated Available Manufacturing 14/11/2025 flecainide acetate Tablet 50 mg Resolved Available Manufacturing 14/11/2025 tofacitinib citrate Solution 1.62 mg/mL Anticipated Available Manufacturing 14/11/2025 mivacurium chloride Injection, solution 2.14 mg/mL Current Unavailable Manufacturing 14/11/2025 rifampicin Capsule, hard 300 mg Current Emergency Supply Only Manufacturing 14/11/2025 benzathine benzylpenicillin tetrahydrate Injection, suspension 1200000 USP Unit Current Emergency Supply Only Manufacturing 13/11/2025 ropivacaine hydrochloride Injection, solution 75 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 13/11/2025 escitalopram oxalate Tablet, film coated 12.774 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 13/11/2025 escitalopram oxalate Tablet, film coated 25.548 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 13/11/2025 acarbose Tablet 100 mg Resolved Available Manufacturing 13/11/2025 irbesartan Tablet, film coated 300 mg Anticipated Available Manufacturing 13/11/2025 irbesartan Tablet, film coated 150 mg Anticipated Available Manufacturing 13/11/2025 bimatoprost Eye Drops .3 mg/mL Anticipated Available Manufacturing 13/11/2025 escitalopram oxalate Tablet, film coated 12.774 mg Anticipated Available Manufacturing 13/11/2025 nitrofurantoin Capsule, hard 100 mg Current Unavailable Unexpected increase in consumer demand 13/11/2025 mitomycin Injection, powder for 20 mg Current Limited Availability Manufacturing 13/11/2025 tobramycin Injection, solution 40 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 13/11/2025 ephedrine sulfate Injection, solution 30 mg/mL Resolved Available Manufacturing 12/11/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Resolved Available Unexpected increase in consumer demand 12/11/2025 mesalazine Granules, modified release 4 g Current Limited Availability Transport / Logistic issues / Storage capacity issues 12/11/2025 levetiracetam Solution 100 mg/mL Current Limited Availability Manufacturing 12/11/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Manufacturing 12/11/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Resolved Available Manufacturing 12/11/2025 metformin hydrochloride Tablet, film coated 1000 mg Current Unavailable Unexpected increase in consumer demand 12/11/2025 lacosamide Tablet, film coated 100 mg Current Limited Availability Manufacturing 12/11/2025 lacosamide Tablet, film coated 50 mg Current Limited Availability Manufacturing 12/11/2025 montelukast sodium Tablet, chewable 5.2 mg Current Unavailable Manufacturing 12/11/2025 isotretinoin Capsule, soft 10 mg Current Unavailable Manufacturing 12/11/2025 adrenaline (epinephrine) Injection, solution 500 microgram Current Unavailable Manufacturing 12/11/2025 daptomycin Injection, powder for 500 mg Current Unavailable Manufacturing 12/11/2025 daptomycin Inhalation, powder for 350 mg Current Unavailable Manufacturing 12/11/2025 spironolactone Tablet, film coated 25 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 12/11/2025 flunitrazepam Tablet, film coated 1 mg Current Limited Availability Manufacturing 12/11/2025 dienogest~ethinylestradiol Tablet, sugar coated 2 mg~.03 mg Discontinued Reduction in supply until supply is exhausted Manufacturing 11/11/2025 nortriptyline Tablet, film coated 10 mg Anticipated Available Manufacturing 11/11/2025 insulin Injection, suspension 100 IU/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 11/11/2025 insulin Injection, solution 100 IU/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 11/11/2025 doxylamine succinate Tablet, uncoated 25 mg Resolved Available Unexpected increase in consumer demand 11/11/2025 milrinone Injection, concentrated 10 mg Current Unavailable Manufacturing 11/11/2025 lamotrigine Tablet, uncoated 100 mg Current Limited Availability Manufacturing 11/11/2025 prasugrel Tablet, film coated 5 mg Current Unavailable Commercial Changes / Commercial viability 11/11/2025 insulin Injection, suspension 100 IU/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 11/11/2025 Insulin lispro Injection, solution 100 IU/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 11/11/2025 cisatracurium besilate Injection, solution 2.68 mg/mL Current Unavailable Manufacturing 11/11/2025 vinorelbine tartrate Injection, concentrated 13.85 mg/mL Discontinued Unavailable Commercial Changes / Commercial viability 11/11/2025 sertraline hydrochloride Tablet, film coated 55.96 mg Current Unavailable Manufacturing 10/11/2025 olanzapine pamoate monohydrate Injection, powder for 690 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 10/11/2025 bethanechol chloride Tablet, uncoated 10 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 10/11/2025 riluzole Tablet, film coated 50 mg Anticipated Available Manufacturing 10/11/2025 cyproterone acetate Tablet, uncoated 50 mg Current Unavailable Manufacturing 10/11/2025 cyproterone acetate Tablet, uncoated 100 mg Anticipated Available Manufacturing 10/11/2025 ambrisentan Tablet, film coated 10 mg Anticipated Available Manufacturing 10/11/2025 acamprosate calcium Tablet, enteric coated 333 mg Anticipated Available Manufacturing 10/11/2025 paroxetine hydrochloride Tablet, film coated 22.22 mg Anticipated Available Manufacturing 10/11/2025 hyoscine butylbromide Injection, solution 20 mg Resolved Available Manufacturing 10/11/2025 ondansetron hydrochloride dihydrate Tablet, film coated 4.986 mg Anticipated Available Manufacturing 10/11/2025 isotretinoin Capsule, soft 10 mg Anticipated Available Manufacturing 10/11/2025 rifampicin Capsule, hard 150 mg Current Limited Availability Manufacturing 10/11/2025 - 2025.11.18
- 2025.11.18
New
November 14, 2025
- Ceftazidime Injection (Discontinuation)
- Palonosetron Hydrochloride Injection (Discontinuation)
- Somatropin Injection (Discontinuation)
- Vancomycin Hydrochloride Injection (Discontinuation)
November 13, 2025
- Adalimumab-ryvk Kit (Discontinuation)
- Cetrorelix Acetate Injection (Discontinuation)
- Guanfacine Hydrochloride Tablet, Extended Release (Discontinuation)
November 12, 2025
- Frovatriptan Succinate Tablet (Discontinuation)
Updated
November 14, 2025
- Bupivacaine Hydrochloride Injection (Currently in Shortage)
- Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Currently in Shortage)
- Carboplatin Injection (Currently in Shortage)
- Clindamycin Phosphate Injection (Currently in Shortage)
- Dextrose Monohydrate 5% Injection (Currently in Shortage)
- Dobutamine Hydrochloride Injection (Currently in Shortage)
- Dopamine Hydrochloride Injection (Currently in Shortage)
- Epinephrine Bitartrate, Lidocaine Hydrochloride Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Ketorolac Tromethamine Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Lorazepam Injection (Currently in Shortage)
- Meperidine Hydrochloride Injection (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Penicillin G Benzathine Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- Sterile Water Injection (Currently in Shortage)
- Sufentanil Citrate Injection (Currently in Shortage)
November 13, 2025
- Azacitidine Injection (Currently in Shortage)
- Bumetanide Injection (Currently in Shortage)
- Cefotaxime Sodium Powder, for Solution (Currently in Shortage)
- Dexamethasone Sodium Phosphate Injection (Currently in Shortage)
- Dopamine Hydrochloride Injection (Currently in Shortage)
- Fentanyl Citrate Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Ketorolac Tromethamine Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Liraglutide Injection (Currently in Shortage)
- Lorazepam Injection (Currently in Shortage)
- Midazolam Hydrochloride Injection (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Promethazine Hydrochloride Injection (Currently in Shortage)
- Propranolol Hydrochloride Injection (Currently in Shortage)
- Remifentanil Hydrochloride Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Sterile Water Injection (Currently in Shortage)
- Sufentanil Citrate Injection (Currently in Shortage)
- Valproate Sodium Injection (Currently in Shortage)
November 10, 2025
- Amino Acid Injection (Currently in Shortage)
- Clindamycin Phosphate Injection (Currently in Shortage)
- Dexmedetomidine Hydrochloride Injection (Currently in Shortage)
- Dextrose Monohydrate 5% Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Heparin Sodium Injection (Currently in Shortage)
- Ketorolac Tromethamine Injection (Currently in Shortage)
- Nitroglycerin Injection (Currently in Shortage)
- Sterile Water Irrigant (Currently in Shortage)
- 2025.11.10
Active ingredients Message type Date of last message Type of reason AM designation Darifenacin hydrobromide Initial report 07.11.2025 Other Darifenacin Aristo 15 mg prolonged-release tablets Tolterodine tartrate Initial report 07.11.2025 Other Tolterodine Aristo 1 mg film-coated tablets Tolterodine tartrate Initial report 07.11.2025 Other Tolterodine-Aristo 2 mg film-coated tablets Posaconazole Change notification 07.11.2025 Other Posaconazole HEXAL 40 mg/ml oral suspension Tolterodine tartrate Initial report 07.11.2025 Other Detrusitol 1 mg film-coated tablets Beclomethasone dipropionate (Ph.Eur.) Change notification 07.11.2025 Other Beclorhinol aquosum 50 micrograms Paliperidone palmitate Change notification 06.11.2025 Other XEPLION 25 mg prolonged-release suspension for injection – OP1ml Rifampicin sodium Change notification 06.11.2025 Other Eremfat i.v. 600mg Nitrendipine Initial report 06.11.2025 Other Nitrendipine AL 10 Urapidil Initial report 06.11.2025 Other Urapidil AL 90 mg hard capsules, delayed release Urapidil Initial report 06.11.2025 Other Urapidil AL 30 mg hard capsules, delayed release Imiquimod Change notification 06.11.2025 Production problem Aldara 5% cream – OP24 Calcium folinate hydrate Change notification 06.11.2025 Production problem Calcium folinate onkovis 10 mg/ml solution for injection Quetiapine fumarate (Ph.Eur.) Change notification 06.11.2025 Other Quetiapine AL 100 mg film-coated tablets Salbutamol sulfate Initial report 05.11.2025 Other Bronchospray Autohaler Imiquimod Change notification 05.11.2025 Production problem Imikeraderm 50 mg/g cream Sodium mycophenolate Initial report 05.11.2025 Other Mycophenolic acid HEXAL 180 mg gastro-resistant tablets Sodium mycophenolate Change notification 05.11.2025 Other Mycophenolic acid HEXAL 360 mg gastro-resistant tablets Sitagliptin hydrochloride monohydrate Change notification 05.11.2025 Production problem Sitagliptin PUREN 50 mg film-coated tablets Nimodipine Change notification 05.11.2025 Other Nimodipine Hexal 30 mg Propranolol hydrochloride Initial report 05.11.2025 Other Propra-ratiopharm 40 mg film-coated tablets Propranolol hydrochloride Initial report 05.11.2025 Other Propra-ratiopharm 10 mg film-coated tablets Dexamethasone dihydrogen phosphate disodium (Ph.Eur.) Initial report 05.11.2025 Other Dexa-ratiopharm 4 mg solution for injection Ipratropium bromide (Ph.Eur.) Change notification 05.11.2025 Production problem Ipratropium Teva 250 micrograms/1 ml solution for nebulizer Buprenorphine Change notification 05.11.2025 Other Buprenorphine AWD Matrix 52.5 micrograms/h Transdermal patch Buprenorphine Change notification 05.11.2025 Other Buprenorphine AWD Matrix 70 micrograms/h Transdermal patch Methylphenidate hydrochloride Change notification 05.11.2025 Other Methylphenidate-ratiopharm 10 mg modified-release hard capsules Galantamine hydrobromide Change notification 05.11.2025 Other Galantamine-ratiopharm 8 mg hard capsules, delayed release Carbamazepine Change notification 05.11.2025 Other Carbamazepine-ratiopharm 200 mg prolonged-release tablets Buprenorphine Change notification 05.11.2025 Other Buprenorphine-ratiopharm 70 micrograms/h transdermal patch Buprenorphine Change notification 05.11.2025 Other Buprenorphine-ratiopharm 52.5 micrograms/h Transdermal patch Buprenorphine Change notification 05.11.2025 Other Buprenorphine-ratiopharm 35 micrograms/h transdermal patch Alprazolam Change notification 05.11.2025 Other Alprazolam-ratiopharm 1.0 mg tablets Methylphenidate hydrochloride Change notification 05.11.2025 Other Methylphenidate-ratiopharm 40 mg modified-release hard capsules Doxepine hydrochloride (Ph.Eur.) Change notification 04.11.2025 Production problem Doxepin 25 Holsten Doxepine hydrochloride (Ph.Eur.) Change notification 04.11.2025 Other Doxepin 50 Holsten Doxepine hydrochloride (Ph.Eur.) Change notification 04.11.2025 Production problem Doxepin 75 Holsten Gabapentin Change notification 04.11.2025 Other Gabapentin Holsten 300 mg hard capsules Gabapentin Change notification 04.11.2025 Production problem Gabapentin Holsten 600 mg film-coated tablets Gabapentin Change notification 04.11.2025 Other Gabapentin Holsten 800 mg film-coated tablets Mercaptopurine Change notification 04.11.2025 Other Mercaptopurine Holsten 50 mg tablets Levetiracetam Change notification 04.11.2025 Other Levetiracetam Holsten 250 mg film-coated tablets Ipratropium bromide (Ph.Eur.); salbutamol sulfate Change notification 04.11.2025 Production problem COMBIPRASAL 0.5 mg / 2.5 mg solution for nebulizer Ipratropium bromide Change notification 04.11.2025 Production problem Ipratropium bromide 250 micrograms / 1 ml Stulln Levetiracetam Initial report 04.11.2025 Other Levetiracetam Holsten 750 mg film-coated tablets Amlodipine besylate; hydrochlorothiazide; valsartan Initial report 04.11.2025 Other Amlodipine/Valsartan/HCT Holsten 5 mg/160 mg/12.5 mg film-coated tablets Docetaxel Initial report 04.11.2025 Production problem Docetaxel Aurobindo 20 mg/ml concentrate for solution for infusion Venlafaxine hydrochloride Initial report 04.11.2025 Other Venlafaxine Aurobindo 75 mg hard capsule, delayed release Topiramate Initial report 04.11.2025 Other Topiramate PUREN 50 mg film-coated tablets Tranexamic acid Initial report 04.11.2025 Production problem Tranexamic acid PUREN 100 mg/ml solution for injection Duloxetine hydrochloride Initial report 04.11.2025 Other Duloxetine PUREN 60 mg gastro-resistant hard capsules Anastrozole Initial report 04.11.2025 Production problem AnastroPUREN 1 mg film-coated tablets Duloxetine hydrochloride Initial report 04.11.2025 Other Duloxetine PUREN 30 mg gastro-resistant hard capsules Quetiapine fumarate (Ph.Eur.) Change notification 04.11.2025 Other Seroquel Prolong 200 mg prolonged-release tablets Insulin lispro Initial report 04.11.2025 Other Humalog KwikPen 100 E/ml solution for injection – OP (5x3ml) Olanzapine Change notification 04.11.2025 Production problem ZYPREXA Ipratropium bromide (Ph.Eur.); salbutamol sulfate Initial report 04.11.2025 Other Ipratropium/salbutamol Cipla 0.5 mg/2.5 mg solution for nebulizer Cefazolin sodium Initial report 04.11.2025 Production problem Cefazolin Hikma 2 g powder for solution for injection/infusion Amiodarone hydrochloride Initial report 04.11.2025 Other Amiodarone PUREN 200 mg tablets Atorvastatin calcium trihydrate (Ph.Eur.) Initial report 04.11.2025 Other Atorvastatin PUREN 80 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 04.11.2025 Other Atorvastatin PUREN 20 mg film-coated tablets Methylphenidate hydrochloride Change notification 04.11.2025 Other Methylphenidate hydrochloride HEXAL 36 mg prolonged-release tablets Atomoxetine hydrochloride Change notification 04.11.2025 Other Atomoxe – 1 A Pharma 100 mg hard capsules Topiramate Change notification 04.11.2025 Production problem Topiramate PUREN 100 mg film-coated tablets Atomoxetine hydrochloride Change notification 04.11.2025 Other Atomoxe – 1 A Pharma 18 mg hard capsules Atomoxetine hydrochloride Change notification 04.11.2025 Other Atomoxe – 1 A Pharma 25 mg hard capsules Atomoxetine hydrochloride Change notification 04.11.2025 Other Atomoxe – 1 A Pharma 40 mg hard capsules Quetiapine fumarate (Ph.Eur.) Change notification 04.11.2025 Other Seroquel Prolong 400 mg prolonged-release tablets Atomoxetine hydrochloride Change notification 04.11.2025 Other Atomoxe – 1 A Pharma 60 mg hard capsules Atomoxetine hydrochloride Change notification 04.11.2025 Other Atomoxe – 1 A Pharma 80 mg hard capsules Urapidil Change notification 04.11.2025 Production problem Urapidil Bluefish 30 mg hard capsules, delayed release Urapidil Change notification 04.11.2025 Production problem Urapidil Bluefish 90 mg hard capsules, delayed release Quetiapine fumarate (Ph.Eur.) Initial report 04.11.2025 Other Seroquel Prolong 150 mg prolonged-release tablets Aprepitant Initial report 03.11.2025 Production problem Aprepitant Zentiva 80 mg hard capsules Aprepitant Initial report 03.11.2025 Production problem Aprepitant Zentiva 125 mg hard capsules Aprepitant Change notification 03.11.2025 Production problem Aprepitant Zentiva 80 mg and 125 mg hard capsules Dimenhydrinate Initial report 03.11.2025 Production problem Dimenhydrinate PANPHARMA 6.2 mg/ml solution for injection (i.v.) Zonisamide Initial report 03.11.2025 Production problem Zonisamide Glenmark 100 mg hard capsules Anastrozole Change notification 03.11.2025 Other Anastrozole Denk 1 mg film-coated tablets Perindopril tert-butylamine Initial report 03.11.2025 Other Perindopril Erbumine Glenmark 4 mg tablets Riluzole Initial report 03.11.2025 Other Glentek 50 mg film-coated tablets Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y) Change notification 03.11.2025 Other Ferrlecit 62.5 mg Clonidine hydrochloride Change notification 03.11.2025 Other Clonidine-ratiopharm 75 Rizatriptan benzoate Change notification 03.11.2025 Production problem Rizatriptan Glenmark 5 mg tablets Clonidine hydrochloride Change notification 03.11.2025 Other Clonidine-ratiopharm 150 Rizatriptan benzoate Change notification 03.11.2025 Production problem Rizatriptan Glenmark 5 mg orodispersible tablets Clonidine hydrochloride Change notification 03.11.2025 Other Clonidine-ratiopharm 300 Rizatriptan benzoate Change notification 03.11.2025 Production problem Rizatriptan Glenmark 10 mg orodispersible tablets Rizatriptan benzoate Change notification 03.11.2025 Production problem Rizatriptan Glenmark 10 mg tablets Quetiapine fumarate (Ph.Eur.) Change notification 03.11.2025 Production problem Quetiapine Glenmark 200 mg prolonged-release tablets Fusidic acid (Ph.Eur.) Change notification 03.11.2025 Production problem Fucithalmic 10 mg/g eye drops Dexketoprofen trometamol Change notification 03.11.2025 Production problem Sympal inject 50 mg solution for injection/infusion Hydrocortisone acetate (Ph.Eur.) Change notification 03.11.2025 Production problem Hydrocortisone-POS N 2.5% Dexamethasone dihydrogen phosphate disodium (Ph.Eur.); gentamicin sulfate Change notification 03.11.2025 Production problem Dexa-Gentamicin Prednisolone acetate Change notification 03.11.2025 Production problem Predni-POS 1% Aciclovir Change notification 03.11.2025 Production problem Virupos Fluorometholone Change notification 03.11.2025 Production problem Fluoropos Gentamicin sulfate Change notification 03.11.2025 Production problem Gentamicin-POS Phenylephrine hydrochloride Change notification 03.11.2025 Production problem Neosynephrine-POS 5% - 2025.11.10
Active ingredients Status Update Specialty diltiazem (hydrochloride) Supply tension 07/11/2025 Tildiem 25 mg, powder and solution for intravenous injection tolvaptan Supply tension 07/11/2025 Tolvaptan Biogaran 30 mg, tablet + Tolvaptan Biogaran 60 mg, tablet urokinase Return to availability 07/11/2025 Thérasolv 250,000 IU, powder for solution for injection/infusion diltiazem (hydrochloride) Marketing discontinuation 07/11/2025 Tildiem 100 mg, powder for solution for injection (IV) chlorpromazine (hydrochloride) Stock shortage 07/11/2025 Largactil 100 mg, film-coated tablet pertuzumab/trastuzumab Return to availability 07/11/2025 Phesgo 1200 mg/600 mg, solution for injection clomipramine (hydrochloride) Supply tension 06/11/2025 Clomipramine Viatris 25 mg, film-coated tablet ornidazole Return to availability 05/11/2025 Tiberal 500 mg, solution for infusion cyamemazine Stock shortage 03/11/2025 Tercian 50 mg/5 mL, injectable solution in ampoule - 2025.11.10
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated betiatide Injection, powder for 1 mg Current Emergency Supply Only Manufacturing 7/11/2025 tobramycin Injection, solution 80 mg Anticipated Available Manufacturing 7/11/2025 primidone Tablet, uncoated 250 mg Current Emergency Supply Only Manufacturing 7/11/2025 trandolapril Capsule 2 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 7/11/2025 topiramate Tablet, film coated 25 mg Current Unavailable Manufacturing 7/11/2025 sodium lactate~magnesium chloride hexahydrate~glucose~sodium chloride~calcium chloride dihydrate Solution, irrigation 4.48 g/L~50.8 mg/L~15 g/L~5.38 g/L~183 mg/L Resolved Available Manufacturing 7/11/2025 glucose~sodium chloride~sodium lactate~magnesium chloride hexahydrate~calcium chloride dihydrate Solution, irrigation 25 g/L~5.38 g/L~4.48 g/L~50.8 mg/L~183 mg/L Resolved Available Manufacturing 7/11/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 7/11/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Manufacturing 7/11/2025 ondansetron hydrochloride dihydrate Tablet, film coated 4.986 mg Anticipated Available Manufacturing 7/11/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Current Unavailable Manufacturing 7/11/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 7/11/2025 galantamine hydrobromide Capsule, modified release 30.756 mg Current Unavailable Manufacturing 7/11/2025 sumatriptan succinate Tablet, film coated 69.99 mg Current Limited Availability Manufacturing 7/11/2025 phenobarbital Tablet, uncoated 30 mg Current Unavailable Manufacturing 7/11/2025 carbidopa monohydrate~entacapone~levodopa Tablet, film coated 27 mg~200 mg~100 mg Current Limited Availability Unexpected increase in consumer demand 7/11/2025 levodopa~carbidopa monohydrate~entacapone Tablet, film coated 150 mg~40.5 mg~200 mg Current Unavailable Unexpected increase in consumer demand 7/11/2025 levodopa~carbidopa monohydrate~entacapone Tablet, film coated 200 mg~54.1 mg~200 mg Current Limited Availability Unexpected increase in consumer demand 7/11/2025 ezetimibe Tablet, uncoated 10 mg Current Limited Availability Unexpected increase in consumer demand 7/11/2025 ezetimibe Tablet, uncoated 10 mg Current Unavailable Unexpected increase in consumer demand 7/11/2025 mebeverine hydrochloride Tablet, film coated 135 mg Current Limited Availability Manufacturing 7/11/2025 latanoprost Eye Drops, solution .05 mg/mL Anticipated Available Manufacturing 7/11/2025 metaraminol tartrate Injection, solution 19 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 7/11/2025 aprepitant Capsule 165 mg Anticipated Available Manufacturing 7/11/2025 fingolimod hydrochloride Capsule 560 microgram Anticipated Available Manufacturing 7/11/2025 lamotrigine Tablet, chewable 100 mg Current Unavailable Manufacturing 7/11/2025 valsartan~sacubitril Tablet, film coated 51.4 mg~48.6 mg Current Unavailable Manufacturing 7/11/2025 sacubitril~valsartan Tablet, film coated 24.3 mg~25.7 mg Current Unavailable Manufacturing 7/11/2025 sitagliptin hydrochloride monohydrate~metformin hydrochloride Tablet, modified release 56.685 mg~1000 mg Current Limited Availability Manufacturing 7/11/2025 nitrofurantoin Capsule, hard 50 mg Anticipated Available Manufacturing 7/11/2025 naltrexone hydrochloride Tablet, film coated 50 mg Anticipated Available Manufacturing 7/11/2025 rivaroxaban Tablet, film coated 10 mg Resolved Available Manufacturing 7/11/2025 carbidopa monohydrate~levodopa Tablet, uncoated 26.9 mg~100 mg Resolved Available Manufacturing 7/11/2025 bumetanide Tablet, uncoated 1 mg Current Limited Availability Manufacturing 7/11/2025 diltiazem hydrochloride Capsule, modified release 360 mg Current Limited Availability Manufacturing 7/11/2025 magnesium chloride hexahydrate~calcium chloride dihydrate~sodium lactate~sodium chloride~icodextrin Solution, dialysis 51 mg/L~257 mg/L~4.5 g/L~5.4 g/L~75 g/L Resolved Available Manufacturing 7/11/2025 nizatidine Capsule, hard 300 mg Anticipated Available Manufacturing 7/11/2025 galantamine hydrobromide~galantamine Capsule, modified release 20.51 mg~16 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 7/11/2025 lamotrigine Tablet, dispersible 200 mg Current Limited Availability Manufacturing 7/11/2025 sodium amidotrizoate~amidotrizoate meglumine Oral Liquid, solution 100 mg/mL~660 mg/mL Discontinued Unavailable Seasonal depletion of stock 6/11/2025 live varicella vaccine Injection, powder for 2700 PFU/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 6/11/2025 minoxidil Tablet, uncoated 10 mg Anticipated Available Manufacturing 6/11/2025 ropivacaine hydrochloride Injection, solution 75 mg Anticipated Available Transport / Logistic issues / Storage capacity issues 6/11/2025 Infliximab Injection, powder for 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 6/11/2025 montelukast sodium Tablet, chewable 4.16 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 6/11/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 6/11/2025 verapamil hydrochloride Tablet, modified release 240 mg Current Limited Availability Manufacturing 5/11/2025 terbutaline sulfate Injection, solution .5 mg/mL Anticipated Available Manufacturing 5/11/2025 midazolam Injection, solution 5 mg/mL Resolved Available Manufacturing 5/11/2025 pantoprazole sodium sesquihydrate Tablet, enteric coated 45.4 mg Resolved Available Unexpected increase in consumer demand 5/11/2025 Alteplase Injection, powder for 50 mg Current Limited Availability Unexpected increase in consumer demand 5/11/2025 montelukast sodium Tablet, chewable 5.2 mg Resolved Available Manufacturing 5/11/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 5/11/2025 amlodipine besilate~atorvastatin calcium trihydrate Tablet, film coated 13.88 mg~10.844 mg Current Unavailable Manufacturing 5/11/2025 mesalazine Granules, modified release 4 g Current Limited Availability Transport / Logistic issues / Storage capacity issues 5/11/2025 dabigatran etexilate mesilate Capsule, hard 172.95 mg Current Unavailable Manufacturing 5/11/2025 doxepin hydrochloride Capsule, hard 11.3 mg Anticipated Available Manufacturing 5/11/2025 midodrine hydrochloride Tablet 5 mg Current Unavailable Manufacturing 5/11/2025 larotrectinib sulfate Capsule, hard 30.7 mg Resolved Available Unexpected increase in consumer demand 5/11/2025 tenofovir disoproxil succinate~emtricitabine Tablet, film coated 300.6 mg~200 mg Current Unavailable Manufacturing 5/11/2025 flecainide acetate Tablet 50 mg Current Unavailable Manufacturing 5/11/2025 rivaroxaban Tablet, film coated 10 mg Anticipated Available Manufacturing 5/11/2025 rivaroxaban Tablet, film coated 15 mg Anticipated Available Manufacturing 5/11/2025 furosemide Injection, solution 20 mg Resolved Available Manufacturing 5/11/2025 ethinylestradiol~norethisterone Tablet, uncoated 36 microgram~500 microgram Current Limited Availability Manufacturing 5/11/2025 Alteplase Diluent, not applicable 10 mg Current Limited Availability Unexpected increase in consumer demand 5/11/2025 fluorouracil Injection, solution 50 mg/mL Resolved Available Unexpected increase in consumer demand 5/11/2025 flunitrazepam Tablet, film coated 1 mg Anticipated Available Manufacturing 5/11/2025 indometacin Suppository, moulded 100 mg Current Unavailable Manufacturing 4/11/2025 ropivacaine hydrochloride Injection, solution 10 mg/mL Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 4/11/2025 ropivacaine hydrochloride Injection, solution 7.5 mg/mL Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 4/11/2025 alfentanil hydrochloride Injection, solution 1.0876 mg Resolved Available Transport / Logistic issues / Storage capacity issues 4/11/2025 nystatin Oral Liquid, suspension 100000 IU/mL Current Unavailable Unexpected increase in consumer demand 4/11/2025 pregabalin Capsule, hard 25 mg Current Unavailable Manufacturing 4/11/2025 escitalopram oxalate Tablet, film coated 12.74 mg Current Unavailable Commercial Changes / Commercial viability 4/11/2025 escitalopram oxalate Tablet, film coated 25.47 mg Current Limited Availability Manufacturing 4/11/2025 lacosamide Tablet, film coated 150 mg Current Limited Availability Manufacturing 4/11/2025 montelukast sodium Tablet, chewable 5.2 mg Current Unavailable Manufacturing 4/11/2025 levothyroxine sodium Tablet, uncoated .05 mg Current Limited Availability Manufacturing 4/11/2025 ramipril Tablet, uncoated 1.25 mg Resolved Available Transport / Logistic issues / Storage capacity issues 4/11/2025 ramipril Tablet, uncoated 2.5 mg Current Limited Availability Manufacturing 4/11/2025 ropivacaine hydrochloride Injection, solution 7.5 mg/mL Current Limited Availability Manufacturing 4/11/2025 ropivacaine hydrochloride Injection, solution 7.5 mg/mL Current Unavailable Manufacturing 4/11/2025 sertraline hydrochloride Tablet, film coated 55.96 mg Current Unavailable Manufacturing 3/11/2025 clozapine Oral Liquid, suspension 50 mg/mL Current Unavailable Manufacturing 3/11/2025 risperidone Tablet 1 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 3/11/2025 lamivudine Tablet, film coated 300 mg Anticipated Available Manufacturing 3/11/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 3/11/2025 olanzapine Tablet, orally disintegrating 10 mg Resolved Available Manufacturing 3/11/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 3/11/2025 finasteride Tablet, film coated 5 mg Current Limited Availability Manufacturing 3/11/2025 risperidone Tablet, film coated .5 mg Resolved Available Manufacturing 3/11/2025 entecavir Tablet, film coated 1 mg Anticipated Available Manufacturing 3/11/2025 primaquine phosphate Tablet, uncoated 13.2 mg Current Emergency Supply Only Manufacturing 3/11/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 3/11/2025 nicorandil Tablet, uncoated 20 mg Anticipated Available Manufacturing 3/11/2025 tobramycin Inhalation, conventional 60 mg/mL Anticipated Available Manufacturing 3/11/2025 phenytoin sodium Capsule, hard 30 mg Resolved Available Manufacturing 3/11/2025 bendamustine hydrochloride Injection, powder for 25 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 3/11/2025 finasteride Tablet, film coated 1 mg Anticipated Available Manufacturing 3/11/2025 Tocilizumab Injection, solution 162 mg Anticipated Available Manufacturing 3/11/2025 bleomycin sulfate Injection, powder for 15000 IU Anticipated Available Manufacturing 3/11/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated 1 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 3/11/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated .125 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 3/11/2025 - 2025.11.10
- 2025.11.10
New
November 07, 2025
- Atropine Sulfate Injection (Discontinuation)
- Calcium Chloride Injection (Discontinuation)
- Deferiprone Tablet (Discontinuation)
- Dextrose Monohydrate 50% Injection (Discontinuation)
- Epinephrine Injection (Discontinuation)
- Ketamine Hydrochloride Injection (Discontinuation)
- Lidocaine Hydrochloride Injection (Discontinuation)
- Sodium Bicarbonate Injection (Discontinuation)
November 03, 2025
- Acetaminophen; Oxycodone Hydrochloride Tablet (Discontinuation)
- Atazanavir Sulfate; Cobicistat Tablet (Discontinuation)
- Everolimus Tablet (Discontinuation)
- Lasmiditan Succinate Tablet (Discontinuation)
- Scopolamine Transdermal System (Discontinuation)
Updated
November 07, 2025
- Atropine Sulfate Injection (Currently in Shortage)
- Dextrose Monohydrate 50% Injection (Currently in Shortage)
- Hydrocortisone Sodium Succinate Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
November 06, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Azacitidine Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Remifentanil Hydrochloride Injection (Currently in Shortage)
November 05, 2025
- Carboplatin Injection (Currently in Shortage)
- Desmopressin Acetate Spray (Currently in Shortage)
- Epinephrine Bitartrate, Lidocaine Hydrochloride Injection (Currently in Shortage)
- Fentanyl Citrate Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Lorazepam Injection (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Sterile Water Injection (Currently in Shortage)
November 04, 2025
- Azacitidine Injection (Currently in Shortage)
- Carboplatin Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Metronidazole Injection (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
November 03, 2025
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- 2025.11.05
- 2025.11.03
Active ingredients Message type Date of last message Type of reason AM designation Nimodipine Change notification 31.10.2025 Other Nimotop S Galantamine hydrobromide Change notification 31.10.2025 Other Galantamine – 1A Pharma 24 mg delayed-release hard capsules Nimodipine Initial report 31.10.2025 Other Nimotop Galantamine hydrobromide Change notification 31.10.2025 Other Galantamine – 1A Pharma 16 mg delayed-release hard capsules Sertraline hydrochloride Initial report 31.10.2025 Other Zoloft 20 mg/ml concentrate for oral solution Ciprofloxacin hydrochloride monohydrate Change notification 30.10.2025 Other CIPRO BASICS 750 mg film-coated tablets Ciprofloxacin hydrochloride monohydrate Change notification 30.10.2025 Other CIPRO BASICS 250 mg film-coated tablets Atorvastatin calcium trihydrate (Ph.Eur.) Change notification 30.10.2025 Other ATORVASTATIN BASICS 80 mg film-coated tablets Ezetimibe; simvastatin Change notification 30.10.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/80 mg tablets Ezetimibe; simvastatin Change notification 30.10.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/40 mg tablets Ezetimibe; simvastatin Change notification 30.10.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/20 mg tablets Ezetimibe; simvastatin Change notification 30.10.2025 Production problem EZETIMIBE/SIMVA BASICS 10 mg/10 mg tablets Esomeprazole hemimagnesium Change notification 30.10.2025 Production problem ESOMEPRAZOLE BASICS 20 mg gastro-resistant hard capsules Esomeprazole hemimagnesium Change notification 30.10.2025 Production problem ESOMEPRAZOLE BASICS 40 mg gastro-resistant hard capsules Isotretinoin Change notification 30.10.2025 Other ISOTRETINOIN BASICS 10 mg soft capsules Isophan insulin suspension for injection (Ph.Eur.) Initial report 30.10.2025 Other Protaphane Penfill 100 IU/ml injection suspension in cylinder ampoule – OP(10x3ml) Flecainide acetate Change notification 30.10.2025 Other Tambocor Moxifloxacin hydrochloride (Ph.Eur.) ((with information on water content (1:x))) Change notification 30.10.2025 Other Moxifloxacin Holsten 400 mg film-coated tablets Doxepin hydrochloride (Ph.Eur.) Initial report 30.10.2025 Other Doxepin 50 Holsten Alprazolam Change notification 30.10.2025 Other Alprazolam – 1 A Pharma 1 mg tablets Oxcarbazepine Change notification 30.10.2025 Other Oxcarbazepine – 1 A Pharma 60 mg/ml oral suspension Flutamide Change notification 30.10.2025 Production problem FLUTA-cell 250 mg tablets Voriconazole Initial report 29.10.2025 Other VFEND 200 mg film-coated tablets Doxepin hydrochloride (Ph.Eur.) Change notification 29.10.2025 Other Doxepin 75 Holsten Doxepin hydrochloride (Ph.Eur.) Change notification 29.10.2025 Production problem Doxepin 25 Holsten Methylphenidate hydrochloride Change notification 29.10.2025 Other Methylphenidate AL 36 mg prolonged-release tablets Methylphenidate hydrochloride Change notification 29.10.2025 Other Metiphenal 10 mg modified-release hard capsules Posaconazole Change notification 29.10.2025 Other Posaconazole AL 40 mg/ml oral suspension Methylphenidate hydrochloride Change notification 29.10.2025 Other Methylphenidate AL 27 mg prolonged-release tablets Aprepitant Change notification 29.10.2025 Other Aprepitant AL 80 mg hard capsules Levothyroxine sodium Change notification 28.10.2025 Production problem L-thyroxine Henning 125 (4′-O-(13)C)Methacetin Change notification 28.10.2025 Production problem LiMAxetin 4 mg/ml solution for injection Besilesomab Initial report 28.10.2025 Production problem Scintimun Besilesomab Initial report 28.10.2025 Production problem Scintimun Levetiracetam Change notification 28.10.2025 Other Levetiracetam – 1 A Pharma 1500 mg film-coated tablets Olanzapine embonate monohydrate Initial report 28.10.2025 Production problem ZYPADHERA 210 mg powder and solvent for the preparation of a prolonged-release suspension for injection – OP(483mg+3ml) Paliperidone palmitate Initial report 28.10.2025 Other Paliperidone AL 25 mg prolonged-release injection suspension in a pre-filled syringe Paliperidone palmitate Change notification 28.10.2025 Other Paliperidone AL 50 mg depot injection suspension in a pre-filled syringe Olanzapine Change notification 28.10.2025 Production problem ZYPREXA Fluphenazine decanoate Change notification 28.10.2025 Production problem Fluphenazine-neuraxpharm D 50 mg/0.5 ml Fluphenazine decanoate Change notification 28.10.2025 Production problem Fluphenazine-neuraxpharm D 12.5 mg/0.5 ml Fluphenazine decanoate Change notification 28.10.2025 Production problem Fluphenazine-neuraxpharm D 25 mg/ml Fluphenazine decanoate Change notification 28.10.2025 Production problem Fluphenazine-neuraxpharm D 100 mg/ml Atomoxetine hydrochloride Change notification 28.10.2025 Production problem Atomoxetine-neuraxpharm 60 mg hard capsules Atomoxetine hydrochloride Change notification 28.10.2025 Production problem Atomoxetine-neuraxpharm 10 mg hard capsules Atomoxetine hydrochloride Change notification 28.10.2025 Production problem Atomoxetine-neuraxpharm 18 mg hard capsules Atomoxetine hydrochloride Change notification 28.10.2025 Production problem Atomoxetine-neuraxpharm 25 mg hard capsules Atomoxetine hydrochloride Change notification 28.10.2025 Production problem Atomoxetine-neuraxpharm 40 mg hard capsules Atomoxetine hydrochloride Change notification 28.10.2025 Production problem Atomoxetine-neuraxpharm 80 mg hard capsules Atomoxetine hydrochloride Change notification 28.10.2025 Production problem Atomoxetine-neuraxpharm 100 mg hard capsules Haloperidol decanoate Change notification 28.10.2025 Production problem Haloperidol-neuraxpharm decanoate 50 mg/ml Haloperidol decanoate Change notification 28.10.2025 Production problem Haloperidol-neuraxpharm decanoate 100 mg/ml Quetiapine fumarate (Ph.Eur.) Change notification 28.10.2025 Other Quetiapine-neuraxpharm 50 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 28.10.2025 Other Quetiapine-neuraxpharm 150 mg prolonged-release tablets Flutamide Change notification 28.10.2025 Other Flutamide AL 250 Quetiapine fumarate (Ph.Eur.) Change notification 28.10.2025 Other Quetiapine-neuraxpharm 200 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 28.10.2025 Other Quetiapine-neuraxpharm 300 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 28.10.2025 Other Quetiapine-neuraxpharm 400 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 28.10.2025 Other Quetiapine-neuraxpharm 600 mg prolonged-release tablets Biperiden hydrochloride Change notification 28.10.2025 Production problem Biperiden-neuraxpharm 2 mg Biperiden hydrochloride Change notification 28.10.2025 Production problem Biperiden-neuraxpharm 4 mg Methylphenidate hydrochloride Change notification 28.10.2025 Other Methylphenidate hydrochloride-neuraxpharm 27 mg prolonged-release tablets Sodium (methylprednisolone-21-succinate) Change notification 28.10.2025 Other Urbason soluble forte 1000 mg Isosorbide mononitrate Change notification 28.10.2025 Production problem ISMN STADA 50 mg hard capsules, delayed release Aprepitant Change notification 28.10.2025 Production problem Aprepitant STADA 125 mg and 80 mg hard capsules Pramipexole dihydrochloride monohydrate Change notification 28.10.2025 Production problem Pramipexole STADA 0.52 mg prolonged-release tablets Aprepitant Change notification 28.10.2025 Production problem Aprepitant STADA 80 mg hard capsules Aprepitant Change notification 28.10.2025 Production problem Aprepitant STADA 125 mg hard capsules Gabapentin Change notification 27.10.2025 Other Gabapentin Holsten 100 mg hard capsules Tetrabenazine Initial report 27.10.2025 Other Tetrabenazine Aristo 25 mg tablets Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y) Change notification 27.10.2025 Other Ferrlecit 62.5 mg Cefaclor monohydrate Change notification 27.10.2025 Other Cefaclor 125 TS – 1 A Pharma Methyldopa (Ph.Eur.) Change notification 27.10.2025 Other Dopegyt tablets Insulin glargine Change notification 27.10.2025 Other Semglee 100 units/ml solution for injection in pre-filled pen – OP(5x3ml) Sufentanil citrate Initial report 27.10.2025 Production problem Sufenta mite Arsenic(III) oxide Change notification 27.10.2025 Production problem Arsenic trioxide STADA 1 mg/ml concentrate for solution for infusion - 2025.11.03
Active ingredients Statut Update Specialty caffeine, opium (dry extract of), paracetamol Supply tension 31/10/2025 Lamaline, suppository mesalazine Supply tension 31/10/2025 Pentasa 1 g and 2 g, granules in sachets, and Pentasa 1 g, suppositories demeclocycline hydrochloride Stock shortage 31/10/2025 Alkonatrem 150 mg, capsule Immunoglobuline humaine rabique Marketing discontinuation 31/10/2025 Imogam Rage 150 UI/mL, solution injectable clarithromycin Return to availability 31/10/2025 Clarithromycin, 250 and 500 mg, modified-release film-coated tablet and film-coated tablet clarithromycin Return to availability 31/10/2025 Clarithromycin Arrow 25 mg/mL, granules for oral suspension clarithromycin Return to availability 31/10/2025 Clarithromycin 50 mg/mL, granules for oral suspension Return to availability 31/10/2025 Copper 6 mg/1 mL Histidine 117.20 mg/3 mL AP-HP, injectable solution, CIPH code 77772737 chlorpromazine (hydrochloride) Stock shortage 31/10/2025 Largactil 100 mg, film-coated tablet acide ascorbique Supply tension 10/30/2025 Laroscorbine 1 g/5 ml, solution injectable I.V. en ampoule tobramycin Supply tension 10/30/2025 Tobi Podhaler 28 mg, powder for inhalation in capsules cytarabine Return to availability 10/30/2025 Cytarabine Sandoz 100 mg/mL, solution for injection – 1 glass vial(s) of 50 mL varenicline (tartrate) Supply tension 10/30/2025 Champix 0.5 mg and 1 mg, film-coated tablet fluorouracil Supply tension 29/10/2025 Fluorouracil Accord 50 mg/mL, solution for dilution for infusion, 5 mL and 100 mL vials methylprednisolone (sodium hydrogen succinate) Return to availability 29/10/2025 Methylprednisolone Hikma 40 mg, powder for solution for injection lithium (carbonate) Supply tension 29/10/2025 Teralithe 250 mg, breakable tablet lithium (carbonate) Supply tension 29/10/2025 Teralithe LP 400 mg, extended-release breakable tablet bromfenac sodium sesquihydrate Supply tension 28/10/2025 Yellox 0.9 mg/mL, eye drops, solution epoetin beta Supply tension 28/10/2025 NeoRecormon range, injectable solution in pre-filled syringe temozolomide Supply tension 28/10/2025 Temodal 2.5 mg/mL, powder for solution for infusion methylprednisolone (sodium hydrogen succinate) Supply tension 28/10/2025 Methylprednisolone Hikma 500 mg, powder for solution for injection tolvaptan Supply tension 27/10/2025 Jinarc 15 mg tablet + Jinarc 45 mg tablet tolvaptan Stock shortage 27/10/2025 Tolvaptan Teva 15 mg tablet + Tolvaptan Teva 45 mg tablet cyanocobalamin Supply tension 27/10/2025 Vitamin B12 Delagrange 1000 micrograms/2 mL, injectable (IM) and oral solution tolvaptan Stock shortage 27/10/2025 Tolvaptan Biogaran 15 mg, tablet + Tolvaptan Biogaran 45 mg, tablet - 2025.11.03
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated clozapine Oral Liquid, suspension 50 mg/mL Current Unavailable Manufacturing 3/11/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 3/11/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 3/11/2025 bleomycin sulfate Injection, powder for 15000 IU Anticipated Available Manufacturing 3/11/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated 1 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 3/11/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated .125 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 3/11/2025 saxagliptin~dapagliflozin propanediol monohydrate Tablet 5 mg~12.3 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 1/11/2025 dinoprostone Gel .3333 mg/g Anticipated Available Manufacturing 1/11/2025 betiatide Injection, powder for 1 mg Anticipated Available Manufacturing 31/10/2025 phenylephrine hydrochloride Injection, solution 10 mg/mL Anticipated Available Manufacturing 31/10/2025 phenoxymethylpenicillin potassium Oral Liquid, powder for 28.284 mg/mL Resolved Available Manufacturing 31/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 31/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Manufacturing 31/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 31/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 31/10/2025 bisoprolol fumarate Tablet 2.5 mg Resolved Available Manufacturing 31/10/2025 phenobarbital Tablet, uncoated 30 mg Current Limited Availability Manufacturing 31/10/2025 escitalopram oxalate Tablet, film coated 25.548 mg Current Limited Availability Manufacturing 31/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Unexpected increase in consumer demand 31/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Unexpected increase in consumer demand 31/10/2025 bimatoprost Eye Drops .3 mg/mL Current Unavailable Manufacturing 31/10/2025 linezolid Tablet, film coated 600 mg Current Unavailable Manufacturing 31/10/2025 irbesartan Tablet, film coated 300 mg Anticipated Available Manufacturing 31/10/2025 irbesartan Tablet, film coated 150 mg Anticipated Available Manufacturing 31/10/2025 tranexamic acid Tablet, film coated 500 mg Current Unavailable Manufacturing 31/10/2025 olmesartan medoxomil~amlodipine besilate Tablet, film coated 20 mg~6.935 mg Anticipated Available Manufacturing 31/10/2025 rasagiline mesilate Tablet 1.56 mg Current Limited Availability Manufacturing 31/10/2025 rasagiline mesilate Tablet 1.56 mg Current Unavailable Manufacturing 31/10/2025 ambrisentan Tablet, film coated 5 mg Current Limited Availability Manufacturing 31/10/2025 lorazepam Tablet 1 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 31/10/2025 hyoscine butylbromide Injection, solution 20 mg Current Limited Availability Manufacturing 31/10/2025 daptomycin Injection, powder for 500 mg Current Limited Availability Manufacturing 31/10/2025 fentanyl citrate Injection, solution 785 microgram Resolved Available Manufacturing 31/10/2025 famciclovir Tablet, film coated 250 mg Resolved Available Manufacturing 31/10/2025 famciclovir Tablet, film coated 500 mg Resolved Available Manufacturing 31/10/2025 lidocaine hydrochloride monohydrate Injection, solution 10 mg/mL Resolved Available Manufacturing 31/10/2025 lidocaine hydrochloride monohydrate Injection, solution 10 mg/mL Current Limited Availability Manufacturing 31/10/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated .25 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 31/10/2025 lamotrigine Tablet, dispersible 200 mg Anticipated Available Manufacturing 31/10/2025 rifampicin Oral Liquid 20 mg/mL Anticipated Available Unexpected increase in consumer demand 30/10/2025 galantamine hydrobromide Capsule, modified release 20.512 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 30/10/2025 mesalazine Tablet, modified release 1 g Resolved Available Transport / Logistic issues / Storage capacity issues 30/10/2025 lansoprazole Capsule, enteric 30 mg Current Limited Availability Manufacturing 30/10/2025 ondansetron hydrochloride dihydrate Tablet, film coated 9.972 mg Current Limited Availability Manufacturing 30/10/2025 metronidazole Tablet, uncoated 400 mg Current Limited Availability Manufacturing 30/10/2025 naproxen Oral Liquid, suspension 25 mg/mL Resolved Available Manufacturing 30/10/2025 risperidone Tablet, film coated 3 mg Current Limited Availability Manufacturing 30/10/2025 quetiapine fumarate Tablet, modified release 345.39 mg Anticipated Available Manufacturing 30/10/2025 pramipexole dihydrochloride monohydrate Tablet, modified release .75 mg Resolved Available Manufacturing 30/10/2025 pramipexole dihydrochloride monohydrate Tablet, modified release .375 mg Resolved Available Manufacturing 30/10/2025 pramipexole dihydrochloride monohydrate Tablet, modified release 1.5 mg Resolved Available Manufacturing 30/10/2025 pramipexole dihydrochloride monohydrate Tablet, modified release 2.25 mg Resolved Available Manufacturing 30/10/2025 hydrochlorothiazide~irbesartan Tablet, film coated 12.5 mg~300 mg Resolved Available Manufacturing 30/10/2025 atenolol Tablet, film coated 50 mg Resolved Available Manufacturing 30/10/2025 latanoprost Eye Drops, solution .05 mg/mL Anticipated Available Manufacturing 30/10/2025 erlotinib hydrochloride Tablet, film coated 27.32 mg Current Unavailable Unexpected increase in consumer demand 30/10/2025 carvedilol Tablet, film coated 6.25 mg Resolved Available Manufacturing 30/10/2025 thiotepa Injection, powder for 15 mg Current Unavailable Commercial Changes / Commercial viability 30/10/2025 thiotepa Injection, powder for 100 mg Current Unavailable Commercial Changes / Commercial viability 30/10/2025 thiotepa Injection, powder for 400 mg Current Unavailable Commercial Changes / Commercial viability 30/10/2025 Teriparatide Injection, solution .25 mg/mL Resolved Available Unexpected increase in demand due to other sponsors unable to supply 30/10/2025 phenytoin sodium Injection, solution 250 mg Current Limited Availability Manufacturing 30/10/2025 mianserin hydrochloride Tablet, film coated 20 mg Current Limited Availability Manufacturing 30/10/2025 methyldopa sesquihydrate Tablet, film coated 283 mg Current Limited Availability Manufacturing 30/10/2025 pamidronate disodium Injection, concentrated 3 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 30/10/2025 nizatidine Capsule 300 mg Anticipated Available Manufacturing 30/10/2025 simvastatin Tablet, film coated 5 mg Anticipated Available Manufacturing 30/10/2025 verapamil hydrochloride~trandolapril Tablet, film coated 240 mg~4 mg Resolved Available Manufacturing 29/10/2025 calcium polystyrene sulfonate Powder 999.3 mg/g Anticipated Available Manufacturing 29/10/2025 risperidone Tablet, film coated 1 mg Resolved Available Manufacturing 29/10/2025 pentetic acid Injection, powder for 5 mg Current Unavailable Manufacturing 29/10/2025 medronic acid Injection, powder for 10 mg Current Unavailable Manufacturing 29/10/2025 sildenafil citrate Tablet, uncoated 35.1 mg Resolved Available Manufacturing 29/10/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 29/10/2025 ceftazidime pentahydrate Injection, powder for 2.328 g Current Limited Availability Manufacturing 29/10/2025 methylphenidate hydrochloride Capsule, modified release 10 mg Current Limited Availability Manufacturing 29/10/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.9 mg Current Unavailable Unexpected increase in consumer demand 29/10/2025 temozolomide Capsule, hard 5 mg Current Limited Availability Manufacturing 29/10/2025 sodium nitroprusside Injection, solution 50 mg Anticipated Available Manufacturing 29/10/2025 tobramycin Capsule, hard 28 mg Anticipated Available Manufacturing 29/10/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Limited Availability Manufacturing 29/10/2025 atorvastatin calcium trihydrate~amlodipine besilate Tablet, film coated 43.376 mg~13.88 mg Current Limited Availability Manufacturing 29/10/2025 phenoxymethylpenicillin potassium Tablet, film coated 560 mg Current Limited Availability Manufacturing 29/10/2025 rosuvastatin calcium Tablet, film coated 41.68 mg Current Unavailable Manufacturing 29/10/2025 pregabalin Capsule, hard 75 mg Resolved Available Manufacturing 29/10/2025 methylphenidate hydrochloride Capsule, modified release 60 mg Current Limited Availability Manufacturing 29/10/2025 mesalazine Tablet, enteric coated 800 mg Resolved Available Transport / Logistic issues / Storage capacity issues 29/10/2025 hydrocortisone Tablet, uncoated 4 mg Current Limited Availability Manufacturing 29/10/2025 tadalafil Tablet, film coated 5 mg Resolved Available Manufacturing 29/10/2025 risperidone Tablet, film coated .5 mg Anticipated Available Commercial Changes / Commercial viability 29/10/2025 risperidone Tablet, film coated 1 mg Current Unavailable Commercial Changes / Commercial viability 29/10/2025 risperidone Tablet, film coated 2 mg Current Unavailable Commercial Changes / Commercial viability 29/10/2025 risperidone Tablet, film coated 3 mg Current Unavailable Commercial Changes / Commercial viability 29/10/2025 risperidone Tablet, film coated 4 mg Current Unavailable Commercial Changes / Commercial viability 29/10/2025 fluorouracil Injection, solution 50 mg/mL Resolved Available Unexpected increase in consumer demand 29/10/2025 benzathine benzylpenicillin tetrahydrate Injection, suspension 600000 USP Unit Current Unavailable Manufacturing 29/10/2025 lurasidone hydrochloride Tablet, film coated 40 mg Resolved Available Manufacturing 29/10/2025 lurasidone hydrochloride Tablet, film coated 80 mg Resolved Available Manufacturing 29/10/2025 amiodarone hydrochloride Tablet, uncoated 100 mg Resolved Available Manufacturing 29/10/2025 spironolactone Tablet, uncoated 100 mg Resolved Available Manufacturing 29/10/2025 lenalidomide Capsule 5 mg Resolved Available Manufacturing 29/10/2025 sugammadex sodium Injection, solution 217.6 mg Resolved Available Manufacturing 29/10/2025 hydrocortisone hydrogen succinate Injection, powder for 127.6 mg Anticipated Available Manufacturing 29/10/2025 levothyroxine sodium Tablet 50 microgram Resolved Available Unexpected increase in consumer demand 29/10/2025 levothyroxine sodium Tablet 100 microgram Resolved Available Unexpected increase in consumer demand 29/10/2025 sodium chloride Injection, intravenous infusion 9 g/L Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 29/10/2025 dorzolamide hydrochloride Eye Drops, solution 22.26 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 29/10/2025 labetalol hydrochloride Tablet, film coated 100 mg Current Unavailable Manufacturing 29/10/2025 methylphenidate hydrochloride Capsule, modified release 20 mg Current Unavailable Manufacturing 29/10/2025 methylphenidate hydrochloride Capsule, modified release 30 mg Current Unavailable Manufacturing 29/10/2025 methylphenidate hydrochloride Capsule, modified release 40 mg Current Unavailable Manufacturing 29/10/2025 amoxicillin sodium Injection, powder for 1060 mg Resolved Available Manufacturing 29/10/2025 Rubella virus~Measles virus~live varicella vaccine~Mumps virus Injection, powder for 1000 CCID50~1000 CCID50~1995 PFU~25119 CCID50 Resolved Available Manufacturing 28/10/2025 prazosin hydrochloride Tablet, uncoated 2.19 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 28/10/2025 prazosin hydrochloride Tablet, uncoated 5.476 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 28/10/2025 salbutamol sulfate Inhalation, conventional 6 mg Current Unavailable Manufacturing 28/10/2025 stannous chloride~etifenin Injection, powder for .42 mg~20 mg Current Unavailable Manufacturing 28/10/2025 Somatropin Injection, powder for 12 mg/mL Current Limited Availability Unexpected increase in consumer demand 28/10/2025 hydrocortisone sodium succinate Injection, powder for 134 mg Resolved Available Manufacturing 28/10/2025 enalapril maleate Tablet 5 mg Current Limited Availability Manufacturing 28/10/2025 alfentanil hydrochloride Injection, solution 1.0876 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 28/10/2025 doxylamine succinate Tablet, uncoated 25 mg Current Limited Availability Unexpected increase in consumer demand 28/10/2025 quetiapine fumarate Tablet, modified release 57.5 mg Anticipated Available Unexpected increase in consumer demand 28/10/2025 peramivir Injection, concentrated 10 mg/mL Anticipated Available Commercial Changes / Commercial viability 28/10/2025 topotecan hydrochloride Injection, concentrated 4.346 mg Current Limited Availability Unexpected increase in consumer demand 28/10/2025 stannous chloride dihydrate Injection, powder for 19.2 microgram/mL Resolved Available Manufacturing 28/10/2025 Interferon gamma1b Injection, solution 4 million IU/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 28/10/2025 risperidone Injection, modified release 50 mg Anticipated Available Manufacturing 28/10/2025 Insulin glulisine Injection, solution 3.49 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 28/10/2025 lidocaine hydrochloride Injection, solution 10 mg/mL Resolved Available Manufacturing 27/10/2025 simvastatin~ezetimibe Tablet 80 mg~10 mg Anticipated Available Manufacturing 27/10/2025 ezetimibe~simvastatin Tablet 10 mg~40 mg Anticipated Available Manufacturing 27/10/2025 donepezil hydrochloride Tablet, film coated 5 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 27/10/2025 cyproterone acetate Tablet, uncoated 100 mg Anticipated Available Manufacturing 27/10/2025 fluorouracil Injection, solution 50 mg/mL Current Unavailable Manufacturing 27/10/2025 atorvastatin calcium trihydrate~ezetimibe Tablet, film coated 10.341 mg~10 mg Resolved Available Manufacturing 27/10/2025 emtricitabine~tenofovir disoproxil succinate Tablet, film coated 200 mg~300.6 mg Current Limited Availability Manufacturing 27/10/2025 pentamidine isetionate Injection, powder for 300 mg Anticipated Available Manufacturing 27/10/2025 flecainide acetate Tablet 50 mg Current Unavailable Manufacturing 27/10/2025 GluureaLys(ahx)hbedCC Injection, powder for 25 microgram Current Unavailable Manufacturing 27/10/2025 GluureaLys(ahx)hbedCC Injection, powder for 25 microgram Current Unavailable Manufacturing 27/10/2025 iotroxate meglumine Injection, solution 105.46 mg/mL Resolved Available Transport / Logistic issues / Storage capacity issues 27/10/2025 galantamine hydrobromide~galantamine Capsule, modified release 20.51 mg~16 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 27/10/2025 - 2025.11.03
- 2025.11.03
New
October 31, 2025
- Phenobarbital Tablet (Discontinuation)
October 29, 2025
- Moxifloxacin Injection (Discontinuation)
October 27, 2025
- Pramlintide Acetate Injection (Discontinuation)
Updated
期間中、新たな報告はありません。
2025年10月
- 2025.10.28
Medicine supply notification: Amiodarone 100mg and 200mg tablets
Amiodarone 100mg and 200mg tablets are in limited supply until the week commencing 17 November 2025. Amiodarone suspension remains available (specials), and unlicensed imports of amiodarone of 100mg and 200mg tablets have been sourced (lead times vary).
Source: Community Pharmacy England
Medicine supply notification: Antimicrobial agents used in tuberculosis (TB) treatment
Following the national patient safety alert issued on 29 July 2025, the supply situation for antimicrobial medicines used to treat tuberculosis has significantly improved, and updated information in this medicines supply notification supersedes the alert.
Source: Community Pharmacy England
Mometasone (Asmanex Twisthaler®) dry powder inhalers are being discontinued (200 microgram per dose, 60 dose from Oct 2025; 200 microgram per dose 60 dose and 400 microgram per dose 30 and 60 dose from Feb 2026). Alternative corticosteroid inhalers are can bridge supply gap.
Source: Community Pharmacy England
SSPs for cefalexin oral suspensions sugar free further extended
SSPs for cefalexin 125mg/5ml oral suspension sugar free (SSP077) and cefalexin 250mg/5ml oral suspension sugar free (SSP078) were due to expire on 24 October 2025 but they have now been further extended to Friday 28 November 2025.
Source: Community Pharmacy England
- 2025.10.27
Active ingredients Message type Date of last message Type of reason AM designation Beclometasone dipropionate (Ph.Eur.) Initial report 24.10.2025 Other Beclorhinol aquosum 50 micrograms Rifampicin sodium Change notification 24.10.2025 Other Eremfat i.v. 600mg Nimodipine Initial report 24.10.2025 Other Nimodipine Hexal 30 mg Mivacurium chloride Change notification 23.10.2025 Production problem Mivacron 10mg Lorazepam Change notification 23.10.2025 Other Tavor 2.5 mg Expidet Quetiapine fumarate (Ph.Eur.) Change notification 23.10.2025 Other Quetiapine Hormosan 150 mg prolonged-release tablets Misoprostol Initial report 23.10.2025 Other Angusta 25 microgram tablets Epoetin beta Change notification 23.10.2025 Other NeoRecormon 5000 IU solution for injection in pre-filled syringe – OP6 Epoetin beta Change notification 23.10.2025 Other NeoRecormon 3000 IU solution for injection in pre-filled syringe – OP6 Epoetin beta Change notification 23.10.2025 Other NeoRecormon 4000 IU solution for injection in pre-filled syringe – OP6 Epoetin beta Change notification 23.10.2025 Other NeoRecormon 2000 IU solution for injection in pre-filled syringe – OP6 Insulin lispro Initial report 23.10.2025 Other Liprolog Mix25 100 IU/ml KwikPen injection suspension – OP[2x(5x3ml)] Thiamazole Initial report 22.10.2025 Other Thiamazole 5mg Henning Acetylcholine chloride Change notification 22.10.2025 Production problem Miochol-E Powder and solvent for the preparation of an instillation solution for intraocular use Thiamazole Initial report 22.10.2025 Other Thiamazole 20 mg Henning Quetiapine fumarate (Ph.Eur.) Initial report 22.10.2025 Production problem Quetiapine Accord 400 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Initial report 22.10.2025 Production problem Quetiapine Accord 200 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Initial report 22.10.2025 Production problem Quetiapine Accord 150 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 22.10.2025 Production problem Quetiapine Accord 50 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 22.10.2025 Production problem Quetiapine Accord 300 mg prolonged-release tablets Insulin glargine Change notification 22.10.2025 Other Semglee Pirfenidone Change notification 22.10.2025 Production problem Pirfenidone Accord 801 mg film-coated tablets Amikacin sulfate Change notification 22.10.2025 Production problem Amikacin B. Braun 5 mg/ml solution for infusion Amikacin sulfate Change notification 22.10.2025 Production problem Amikacin B. Braun 2.5 mg/ml solution for infusion Flutamide Initial report 22.10.2025 Other Flutamide AL 250 Carbamazepine Initial report 21.10.2025 Other Timonil Syrup Tinzaparin sodium Initial report 21.10.2025 Production problem innohep 20,000 Anti-Xa I.E./ml Vials Solution for injection Methylphenidate hydrochloride Change notification 21.10.2025 Other Equasym Retard 40 mg modified-release hard capsules Methyldopa (Ph.Eur.) Initial report 21.10.2025 Other Dopegyt tablets Ibuprofen Change notification 21.10.2025 Other IBU-PUREN acute 400 mg film-coated tablets Carbamazepine Change notification 21.10.2025 Other Carbadura 400 mg retard Methylphenidate hydrochloride Change notification 20.10.2025 Other METHYLPHENIDATE 20 mg tablets Human insulin (with manufacturing details) Initial report 20.10.2025 Other Berlinsulin H 30/70 3 ml pen Isotretinoin Initial report 20.10.2025 Other ISOTRETINOIN BASICS 10 mg soft capsules Fampridine Change notification 20.10.2025 Other FAMPRIDIN BASICS 10 mg prolonged-release tablets Pramipexole dihydrochloride monohydrate Change notification 20.10.2025 Other Pramipexole Mylan 0.26 mg prolonged-release tablets Pramipexole dihydrochloride monohydrate Change notification 20.10.2025 Other Pramipexole Mylan 0.52 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Initial report 20.10.2025 Other Seroquel Prolong 300 mg prolonged-release tablets Sodium (hydrocortisone-21-succinate) Change notification 20.10.2025 Production problem Hydrocortisone PANPHARMA 250 mg - 2025.10.27
Active ingredients Statut Update Specialty Synthetic vitamin A concentrate, oily form Marketing discontinuation 24/10/2025 Vitamin A Dulcis 25,000 I.U. per 100 g, ophthalmic ointment bumetanide Return to availability 24/10/2025 Burinex 2 mg/4 ml IV, solution for injection in ampoule methylphenidate hydrochloride Stock shortage 23/10/2025 Concerta LP, extendedrelease tablet paclitaxel Supply tension 23/10/2025 Paclitaxel AHCL 6 mg/ml, dilutable solution for infusion 50 ml and 100 ml vials lithium (carbonate of) Supply tension 23/10/2025 Teralithe 250 mg, scored tablet venlafaxine Supply tension 23/10/2025 Specialties based on Venlafaxine LP 37.5 mg and LP 75 mg sustainedrelease capsules carbamazepine Return to availability 23/10/2025 Carbamazepine Viatris L.P. 200 mg, scored sustainedrelease tablet carbamazepine Return to availability 23/10/2025 Carbamazepine Viatris L.P. 400 mg, scored sustainedrelease tablet chlorpromazine (hydrochloride) Stock shortage 22/10/2025 Largactil 100 mg, scored filmcoated tablet fluorouracil Supply tension 21/10/2025 Fluorouracil Accord 50 mg/ml, solution for diluted infusion, 5 ml and 100 ml bottles fluorouracil Stock shortage 21/10/2025 Fluorouracil Pfizer 50 mg/ml, dilutable solution for infusion 20 ml and 100 ml bottle mitomycin Supply tension 21/10/2025 Mitomycin Accord 20 mg, powder for solution for injection / infusion or intravesical use varenicline (tartrate) Stock shortage 20/10/2025 Champix 0.5 mg and 1 mg, filmcoated tablet liothyronine sodium Supply tension 20/10/2025 Cynomel 0.025 mg, scored tablet emtricitabine/tenofovir disoproxil Return to availability 20/10/2025 Speciality based on emtricitabine/tenofovir disoproxil 200 mg/245 mg, filmcoated tablet - 2025.10.27
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated prazosin hydrochloride Tablet, uncoated 1.095 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 prazosin hydrochloride Tablet, uncoated 2.19 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 prazosin hydrochloride Tablet, uncoated 5.476 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 ramipril Tablet, uncoated 1.25 mg Resolved Available Manufacturing 24/10/2025 trandolapril Capsule 2 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 risperidone Tablet, film coated 2 mg Current Limited Availability Manufacturing 24/10/2025 bisoprolol fumarate Tablet 2.5 mg Current Unavailable Manufacturing 24/10/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.9 mg Current Limited Availability Unexpected increase in consumer demand 24/10/2025 exemestane Tablet, sugar coated 25 mg Anticipated Available Manufacturing 24/10/2025 indapamide hemihydrate Tablet, sugar coated 2.5 mg Current Limited Availability Manufacturing 24/10/2025 ropivacaine hydrochloride Injection, solution 200 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 24/10/2025 clopidogrel besilate Tablet, film coated 112.1 mg Current Unavailable Manufacturing 24/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Unexpected increase in consumer demand 24/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Unexpected increase in consumer demand 24/10/2025 rosuvastatin calcium Tablet, film coated 10.42 mg Current Unavailable Manufacturing 24/10/2025 pregabalin Capsule, hard 150 mg Current Limited Availability Unexpected increase in consumer demand 24/10/2025 levetiracetam Solution 100 mg/mL Resolved Available Manufacturing 24/10/2025 clonidine hydrochloride Tablet 100 microgram Resolved Available Unexpected increase in consumer demand 24/10/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Manufacturing 24/10/2025 tranexamic acid Tablet, film coated 500 mg Current Unavailable Manufacturing 24/10/2025 cyproterone acetate Tablet, uncoated 50 mg Current Unavailable Manufacturing 24/10/2025 hydrocortisone Tablet, uncoated 4 mg Current Limited Availability Manufacturing 24/10/2025 nizatidine Capsule, hard 150 mg Resolved Available Manufacturing 24/10/2025 nizatidine Capsule, hard 150 mg Current Unavailable Manufacturing 24/10/2025 rasagiline mesilate Tablet 1.56 mg Anticipated Available Manufacturing 24/10/2025 ambrisentan Tablet, film coated 10 mg Anticipated Available Manufacturing 24/10/2025 teriflunomide Tablet, film coated 14 mg Current Limited Availability Manufacturing 24/10/2025 gabapentin Tablet, film coated 600 mg Anticipated Available Manufacturing 24/10/2025 hydrochlorothiazide~amlodipine besilate~olmesartan medoxomil Tablet, film coated 12.5 mg~13.9 mg~40 mg Current Limited Availability Manufacturing 24/10/2025 paclitaxel Injection, powder for 100 mg Current Limited Availability Manufacturing 24/10/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 ethinylestradiol~norethisterone Tablet, uncoated 36 microgram~500 microgram Anticipated Available Manufacturing 24/10/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated 1 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 24/10/2025 prazosin hydrochloride Tablet, uncoated 1.1 mg Current Unavailable Manufacturing 24/10/2025 prazosin hydrochloride Tablet, uncoated 2.2 mg Current Unavailable Manufacturing 24/10/2025 prazosin hydrochloride Tablet, uncoated 5.5 mg Current Unavailable Manufacturing 24/10/2025 trandolapril Capsule 4 mg Resolved Available Manufacturing 24/10/2025 dinoprostone Gel .6667 mg/g Anticipated Available Manufacturing 24/10/2025 risperidone Tablet, film coated 2 mg Resolved Available Manufacturing 23/10/2025 topiramate Tablet, film coated 25 mg Current Unavailable Manufacturing 23/10/2025 olanzapine Tablet, orally disintegrating 20 mg Resolved Available Manufacturing 23/10/2025 phenoxymethylpenicillin potassium Oral Liquid, powder for 28.284 mg/mL Current Unavailable Manufacturing 23/10/2025 levetiracetam Tablet, film coated 500 mg Current Unavailable Manufacturing 23/10/2025 levetiracetam Tablet, film coated 1000 mg Current Unavailable Manufacturing 23/10/2025 olanzapine Tablet, orally disintegrating 10 mg Current Unavailable Manufacturing 23/10/2025 olanzapine Tablet, orally disintegrating 5 mg Current Unavailable Manufacturing 23/10/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in consumer demand 23/10/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Limited Availability Manufacturing 23/10/2025 sildenafil citrate Tablet, film coated 28.1 mg Current Unavailable Manufacturing 23/10/2025 isotretinoin Capsule, soft 10 mg Current Unavailable Manufacturing 23/10/2025 isotretinoin Capsule, soft 20 mg Current Unavailable Manufacturing 23/10/2025 ezetimibe~simvastatin Tablet 10 mg~10 mg Current Unavailable Manufacturing 23/10/2025 ezetimibe~simvastatin Tablet 10 mg~20 mg Current Unavailable Manufacturing 23/10/2025 rosuvastatin calcium Tablet, film coated 20.84 mg Current Unavailable Unexpected increase in consumer demand 23/10/2025 ezetimibe Tablet, uncoated 10 mg Current Unavailable Unexpected increase in consumer demand 23/10/2025 irbesartan Tablet, film coated 150 mg Resolved Available Manufacturing 23/10/2025 cyproterone acetate Tablet, uncoated 100 mg Anticipated Available Manufacturing 23/10/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Current Unavailable Manufacturing 23/10/2025 efavirenz~tenofovir disoproxil maleate~emtricitabine Tablet, film coated 600 mg~300 mg~200 mg Current Unavailable Manufacturing 23/10/2025 olmesartan medoxomil~hydrochlorothiazide Tablet 20 mg~12.5 mg Anticipated Available Manufacturing 23/10/2025 bimatoprost Eye Drops .3 mg/mL Anticipated Available Manufacturing 23/10/2025 nitrofurantoin Capsule, hard 100 mg Resolved Available Manufacturing 23/10/2025 Teriparatide Injection, solution .25 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 23/10/2025 naltrexone hydrochloride Tablet, film coated 50 mg Anticipated Available Manufacturing 23/10/2025 levothyroxine sodium Tablet 200 microgram Current Unavailable Unexpected increase in consumer demand 23/10/2025 rivaroxaban Tablet, film coated 10 mg Anticipated Available Manufacturing 23/10/2025 tamoxifen citrate Tablet, uncoated 15.2 mg Current Unavailable Manufacturing 23/10/2025 tamoxifen citrate Tablet, uncoated 30.4 mg Current Unavailable Manufacturing 23/10/2025 isotretinoin Capsule, soft 20 mg Current Unavailable Manufacturing 23/10/2025 isotretinoin Capsule, soft 10 mg Anticipated Available Manufacturing 23/10/2025 mupirocin Ointment 20 mg/g Current Unavailable Manufacturing 23/10/2025 lidocaine hydrochloride Injection, solution 10 mg/mL Resolved Available Manufacturing 23/10/2025 ropivacaine hydrochloride Injection, solution 10 mg/mL Resolved Available Manufacturing 23/10/2025 phenylephrine hydrochloride Injection, solution 10 mg/mL Anticipated Available Manufacturing 22/10/2025 galantamine hydrobromide Capsule, modified release 30.768 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 22/10/2025 mycophenolate mofetil Tablet, film coated 500 mg Current Limited Availability Manufacturing 22/10/2025 letrozole Tablet, film coated 2.5 mg Current Unavailable Manufacturing 22/10/2025 atorvastatin calcium trihydrate~amlodipine besilate Tablet, film coated 43.376 mg~6.94 mg Current Unavailable Manufacturing 22/10/2025 atorvastatin calcium trihydrate~amlodipine besilate Tablet, film coated 10.844 mg~13.88 mg Current Unavailable Manufacturing 22/10/2025 milrinone Injection, concentrated 10 mg Current Unavailable Manufacturing 22/10/2025 fingolimod hydrochloride Capsule 560 microgram Anticipated Available Manufacturing 22/10/2025 phenytoin sodium Injection, solution 250 mg Current Limited Availability Manufacturing 22/10/2025 bromazepam Tablet, uncoated 6 mg Resolved Available Transport / Logistic issues / Storage capacity issues 22/10/2025 bisoprolol fumarate Tablet 2.5 mg Current Unavailable Manufacturing 21/10/2025 ropivacaine hydrochloride Injection, solution 10 mg/mL Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 21/10/2025 clindamycin hydrochloride Capsule, hard 162.87 mg Anticipated Available Manufacturing 21/10/2025 mesalazine Tablet, enteric coated 800 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 21/10/2025 acamprosate calcium Tablet, enteric coated 333 mg Anticipated Available Manufacturing 21/10/2025 moxonidine Tablet, film coated 400 microgram Current Limited Availability Manufacturing 21/10/2025 paroxetine hydrochloride Tablet, film coated 22.22 mg Anticipated Available Manufacturing 21/10/2025 carvedilol Tablet, film coated 6.25 mg Anticipated Available Manufacturing 21/10/2025 lamotrigine Tablet, chewable 100 mg Current Limited Availability Manufacturing 21/10/2025 lamotrigine Tablet, chewable 200 mg Anticipated Available Manufacturing 21/10/2025 ondansetron hydrochloride dihydrate Tablet, film coated 4.986 mg Anticipated Available Manufacturing 21/10/2025 famciclovir Tablet, film coated 250 mg Current Unavailable Manufacturing 21/10/2025 famciclovir Tablet, film coated 500 mg Current Unavailable Manufacturing 21/10/2025 ondansetron hydrochloride dihydrate Injection, solution 5 mg Current Unavailable Manufacturing 20/10/2025 midazolam Injection, solution 50 mg Current Limited Availability Manufacturing 20/10/2025 vecuronium bromide Injection, powder for 10 mg Resolved Available Manufacturing 20/10/2025 salmeterol xinafoate~fluticasone propionate Inhalation, powder for 72.5 microgram/actuation~250 microgram/actuation Resolved Available Unexpected increase in consumer demand 20/10/2025 desvenlafaxine Tablet, modified release 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 20/10/2025 desvenlafaxine Tablet, modified release 50 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 20/10/2025 methylphenidate hydrochloride Capsule, modified release 60 mg Current Limited Availability Manufacturing 20/10/2025 ezetimibe~simvastatin Tablet 10 mg~40 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 20/10/2025 amiodarone hydrochloride Tablet, uncoated 100 mg Current Unavailable Manufacturing 20/10/2025 sugammadex sodium Injection, solution 217.6 mg Current Unavailable Manufacturing 20/10/2025 risperidone Oral Liquid, solution 1 mg/mL Current Limited Availability Manufacturing 20/10/2025 rifampicin Capsule, hard 150 mg Current Limited Availability Manufacturing 20/10/2025 Peginterferon alfa2a Injection, solution 135 microgram Current Unavailable Unexpected increase in consumer demand 20/10/2025 Peginterferon alfa2a Injection, solution 180 microgram Current Unavailable Unexpected increase in consumer demand 20/10/2025 - 2025.10.27
Generic Name Shortage Status Revision Date Amiodarone Injection Current Shortages 22-Oct-25 Clindamycin Phosphate Injection Current Shortages 22-Oct-25 Dexamethasone Oral Solution/Elixir Current Shortages 22-Oct-25 Hydrocortisone Sodium Succinate Injection Resolved Shortages 22-Oct-25 Morphine Injection Current Shortages 22-Oct-25 Sodium Bicarbonate Injection Current Shortages 22-Oct-25 Vasopressin Injection Current Shortages 22-Oct-25 Vecuronium Bromide Injection Current Shortages 22-Oct-25 Albuterol sulfate and Ipratropium Bromide Inhalation Solution Current Shortages 21-Oct-25 Dorzolamide Ophthalmic Solution Current Shortages 21-Oct-25 Nalbuphine Injection Current Shortages 20-Oct-25 Nitroglycerin Injection Current Shortages 20-Oct-25 Penicillin G Benzathine Current Shortages 20-Oct-25 Potassium Chloride Injection Current Shortages 20-Oct-25 - 2025.10.27
New
October 24, 2025
- Busulfan Injection (Discontinuation)
- Insulin Glargine Injection (Discontinuation)
- Insulin Lispro Injection (Discontinuation)
- Insulin Lispro-aabc Injection (Discontinuation)
- Lorazepam Injection (Currently in Shortage)
October 21, 2025
- Tranylcypromine Sulfate Tablet (Discontinuation)
October 20, 2025
- Oxaliplatin Injection (Discontinuation)
Updated
October 24, 2025
- Dexamethasone Sodium Phosphate Injection (Currently in Shortage)
October 23, 2025
- Bupivacaine Hydrochloride Injection (Currently in Shortage)
- Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Lorazepam Injection (Currently in Shortage)
- Meperidine Hydrochloride Injection (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Penicillin G Benzathine Injection (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- Sterile Water Injection (Currently in Shortage)
- Sufentanil Citrate Injection (Currently in Shortage)
October 22, 2025
- Amino Acid Injection (Currently in Shortage)
- Clindamycin Phosphate Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Heparin Sodium Injection (Currently in Shortage)
- Nitroglycerin Injection (Currently in Shortage)
- Sterile Water Irrigant (Currently in Shortage)
October 21, 2025
- Dextrose Monohydrate 10% Injection (Currently in Shortage)
- Fentanyl Citrate Injection (Currently in Shortage)
- Heparin Sodium Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Lisdexamfetamine Dimesylate Tablet, Chewable (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Naltrexone Hydrochloride Tablet (Currently in Shortage)
- Remifentanil Hydrochloride Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Ropivacaine Hydrochloride Injection (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- Technetium TC-99M Pyrophosphate Kit Injection (Currently in Shortage)
- 2025.10.21
Medicine supply notification: Dalivit® oral drops
Dalivit® oral drops are out of stock until further notice. Abidec® multivitamin drops remain available and can support increased demand, but as it contains arachis oil (peanut oil), it should not be taken by patients with peanut or soya allergy.
Medicine supply notification: Exenatide (Bydureon® BCise®) 2mg/0.85ml prolonged-release suspension for injection pre-filled pen
Exenatide (Bydureon® BCise®) 2mg/0.85ml prolonged-release suspension for injection pre-filled pens have been discontinued with supplies now exhausted. Alternative GLP-1 RAs and dual GIP/GLP-1 RA remain available and can support increased demand.
- 2025.10.20
Active ingredients Message type Date of last message Type of reason AM designation Lidocaine hydrochloride monohydrate Change notification 17.10.2025 Other Xylocaine Gel 2% Estriol Initial report 17.10.2025 Other Ovestin 1 mg cream Mivacurium chloride Initial report 17.10.2025 Other Mivacron 10 mg Lidocaine Initial report 17.10.2025 Other XYLOCAIN PUMP SPRAY dental Salbutamol sulfate Change notification 17.10.2025 Other Sultanol forte ready-to-use inhalation solution Levothyroxine sodium Initial report 17.10.2025 Production problem L-thyroxine Henning 50 Levothyroxine sodium Initial report 17.10.2025 Production problem L-thyroxine Henning 125 Levothyroxine sodium Initial report 17.10.2025 Production problem L-Thyroxine Henning 75 Gentamicin sulfate Initial report 17.10.2025 Production problem Gentamicin-POS Phenylephrine hydrochloride Change notification 17.10.2025 Production problem Neosynephrine-POS 5% Fampridine Change notification 17.10.2025 Other FAMPRIDIN BASICS 10 mg prolonged-release tablets Atorvastatin calcium trihydrate (Ph.Eur.) Initial report 17.10.2025 Other ATORVASTATIN BASICS 80 mg film-coated tablets Olanzapine embonate monohydrate Initial report 17.10.2025 Other ZYPADHERA 405 mg powder and solvent for the preparation of a prolonged-release injection suspension – OP(931mg+3ml) Candesartan cilexetil Initial report 17.10.2025 Other ATACAND 16 mg Olanzapine embonate monohydrate Change notification 17.10.2025 Production problem ZYPADHERA 210 mg powder and solvent for the preparation of a prolonged-release suspension for injection – OP(483mg+3ml) Methyldopa (Ph.Eur.) Initial report 17.10.2025 Production problem Presinol 250 Insulin detemir Initial report 17.10.2025 Other Levemir 100 IU solution for injection in pre-filled pen – OP(10x3ml)(FlexPen) Insulin detemir Initial report 17.10.2025 Other Levemir 100 IU injection solution in cartridge – OP(10x3ml) Betamethasone dipropionate (Ph.Eur.); gentamicin sulfate Initial report 16.10.2025 Other Diprogenta Posaconazole Initial report 16.10.2025 Other Posaconazole HEXAL 40 mg/ml oral suspension Oxytocin Initial report 16.10.2025 Production problem Oxytocin 3 IU Hexal Human insulin (with manufacturing details) Initial report 16.10.2025 Other Berlinsulin H Basal 3 ml pen Insulin aspart Change notification 16.10.2025 Other NovoMix 30 FlexPen 100 IU/ml injection suspension in pre-filled syringe – OP(10x3ml) Human insulin (with manufacturing details) Initial report 15.10.2025 Other Berlinsulin H Normal 3 ml pen Methylprednisolone Initial report 15.10.2025 Other Methylprednisolone 4mg JENAPHARM Azithromycin dihydrate Change notification 15.10.2025 Other Azithromycin AL 250 mg film-coated tablets Vancomycin hydrochloride Change notification 15.10.2025 Production problem Vancomycin Lyomark 500 mg Vancomycin hydrochloride Change notification 15.10.2025 Production problem Vancomycin Lyomark 1000 mg powder for concentrate for solution for infusion or oral solution Posaconazole Initial report 15.10.2025 Other Posaconazole AL 40 mg/ml oral suspension Methylphenidate hydrochloride Initial report 15.10.2025 Other Metiphenal 10 mg modified-release hard capsules Folic acid hydrate (with information on water content (1:x)) Initial report 15.10.2025 Other Folic acid AL 5 mg tablets Acitretin Initial report 15.10.2025 Other Acicutan 25 mg hard capsules Fusidic acid (Ph.Eur.) Initial report 15.10.2025 Other Fusicutan ointment Oxazepam Initial report 15.10.2025 Other Durazepam 50 mg forte Oxycodone hydrochloride (Ph.Eur.) Initial report 14.10.2025 Production problem Oxygesic Dispersa acute 5 mg Oxycodone hydrochloride (Ph.Eur.) Initial report 14.10.2025 Production problem Oxygesic Dispersa acute 10 mg Oxycodone hydrochloride Change notification 14.10.2025 Other OXYGESIC 10 mg Arsenic(III) oxide Initial report 14.10.2025 Other TRISENOX 2 mg/ml concentrate for solution for infusion Granisetron hydrochloride Initial report 14.10.2025 Other Kevatril 3 mg/3 ml solution for injection Carboplatin Initial report 14.10.2025 Other Carboplatin Kabi 10 mg/ml concentrate for solution for infusion Dexketoprofen trometamol Initial report 14.10.2025 Production problem Sympal inject 50 mg injection/infusion solution Tolterodine tartrate Initial report 14.10.2025 Other Detrusitol 2 mg film-coated tablets Doxepin hydrochloride (Ph.Eur.) Initial report 14.10.2025 Other Doxepin-ratiopharm 50 mg film-coated tablets Doxepin hydrochloride (Ph.Eur.) Initial report 14.10.2025 Other Doxepin-ratiopharm 25 mg film-coated tablets Thiamazole Initial report 13.10.2025 Other Thiamazole 5 mg Henning Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y) Change notification 13.10.2025 Other Ferrlecit 62.5 mg Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y) Change notification 13.10.2025 Other Ferrlecit 40 mg Cisatracurium besylate Change notification 13.10.2025 Other Nimbex 10 mg Zolbetuximab Change notification 13.10.2025 Other Vyloy Paliperidone palmitate Initial report 13.10.2025 Other XEPLION 50 mg prolonged-release suspension for injection – OP1ml - 2025.10.20
Active ingredients Statut Update Specialty digoxine Supply tension 10/17/2025 Digoxine Nativelle 5 µg/0.1 ml, solution buvable en gouttes pyrantel (embonate of) Supply tension 10/17/2025 Combantrin 125 mg, tablet rifamycin sodium Supply tension 10/17/2025 Rifamycin Chibret 1000 000 IU per cent, eye drops solution risperidone Supply tension 10/17/2025 Risperidone 0.5 mg, 1 mg, 2 mg and 3 mg orodispersible tablet risperidone Out of stock 10/17/2025 Risperidone 4 mg Orodispersible tablet olipudase alfa Supply tension 15/10/2025 Xenpozyme 20 mg, powder for solution to be diluted for infusion pertuzumab/trastuzumab Out of stock 15/10/2025 Phesgo 1200 mg/600 mg, solution injectable risperidone Out of stock 15/10/2025 RisperdalConsta L.P. 37.5 mg/2 ml, powder and solvent for prolongedrelease suspension for injection in prefilled syringe risperidone Supply tension 15/10/2025 RisperdalConsta L.P. 50 mg/2 ml and 25 mg/2 ml, powder and solvent for prolongedrelease suspension for injection in prefilled syringe risperidone Out of stock 15/10/2025 Risperidone L.P. 25 mg/2 ml, 37.5 mg/2 ml and 50 mg/2 ml, powder and solvent for prolongedrelease suspension for injection in prefilled syringe lenalidomide Out of stock 15/10/2025 Lenalidomide Mylan, capsule dipyridamole Supply tension 15/10/2025 Persantine 10 mg/2 mL, solution injectable, ampoule chlorpromazine (hydrochloride) Supply tension 13/10/2025 Largactil 25 mg, filmcoated tablet VaricellaZoster Virus (VZV) glycoprotein E antigen (recombinant, adjuvanted) (mammalian/hamster/CHO cells) Supply tension 13/10/2025 Shingrix, powder and suspension for injectable suspension. Varicella zoster vaccine (recombinant, adjuvanted) esketamine (hydrochloride) Return to availability 13/10/2025 Eskesia 5 mg/mL, solution for injection/infusion 10 glass ampoule(s) of 5 ml - 2025.10.20
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated desvenlafaxine Tablet, modified release 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 20/10/2025 desvenlafaxine Tablet, modified release 50 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 20/10/2025 ezetimibe~simvastatin Tablet 10 mg~40 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 20/10/2025 risperidone Oral Liquid, solution 1 mg/mL Current Limited Availability Manufacturing 20/10/2025 rivaroxaban Tablet, film coated 10 mg Anticipated Available Manufacturing 20/10/2025 rifampicin Capsule, hard 150 mg Current Limited Availability Manufacturing 20/10/2025 phenytoin sodium Injection, solution 100 mg Current Unavailable Manufacturing 17/10/2025 ciprofloxacin hydrochloride Tablet, film coated 555 mg Anticipated Available Manufacturing 17/10/2025 sildenafil citrate Tablet, uncoated 35.1 mg Current Limited Availability Manufacturing 17/10/2025 glipizide Tablet, uncoated 5 mg Anticipated Available Manufacturing 17/10/2025 mesalazine Tablet, modified release 1 g Current Limited Availability Transport / Logistic issues / Storage capacity issues 17/10/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Current Unavailable Manufacturing 17/10/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Current Limited Availability Manufacturing 17/10/2025 montelukast sodium Tablet, chewable 5.2 mg Anticipated Available Manufacturing 17/10/2025 carbidopa monohydrate~levodopa~entacapone Tablet, film coated 54 mg~200 mg~200 mg Current Unavailable Manufacturing 17/10/2025 entacapone~carbidopa monohydrate~levodopa Tablet, film coated 200 mg~20.25 mg~75 mg Current Unavailable Manufacturing 17/10/2025 entacapone~levodopa~carbidopa monohydrate Tablet, film coated 200 mg~50 mg~13.5 mg Current Limited Availability Manufacturing 17/10/2025 levodopa~entacapone~carbidopa monohydrate Tablet, film coated 100 mg~200 mg~27 mg Current Unavailable Manufacturing 17/10/2025 entacapone~levodopa~carbidopa monohydrate Tablet, film coated 200 mg~125 mg~33.75 mg Current Unavailable Manufacturing 17/10/2025 carbidopa monohydrate~levodopa~entacapone Tablet, film coated 40.5 mg~150 mg~200 mg Current Unavailable Manufacturing 17/10/2025 pregabalin Capsule, hard 150 mg Current Limited Availability Unexpected increase in consumer demand 17/10/2025 risperidone Tablet, film coated 2 mg Anticipated Available Manufacturing 17/10/2025 gabapentin Tablet, film coated 600 mg Anticipated Available Manufacturing 17/10/2025 metaraminol tartrate Injection, solution 19 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 17/10/2025 amlodipine besilate~olmesartan medoxomil~hydrochlorothiazide Tablet, film coated 13.9 mg~40 mg~12.5 mg Anticipated Available Manufacturing 17/10/2025 naltrexone hydrochloride Tablet, film coated 50 mg Anticipated Available Manufacturing 17/10/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 17/10/2025 prazosin hydrochloride Tablet, uncoated 1.095 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 tobramycin Injection, solution 80 mg Anticipated Available Manufacturing 16/10/2025 tetracosactide Injection, modified release 1 mg/mL Current Unavailable Manufacturing 16/10/2025 dienogest~ethinylestradiol Tablet, sugar coated 2 mg~.03 mg Anticipated Available Manufacturing 16/10/2025 codeine phosphate hemihydrate Oral Liquid, solution 5 mg/mL Current Unavailable Manufacturing 16/10/2025 ciprofloxacin hydrochloride Tablet, film coated 277.5 mg Current Unavailable Manufacturing 16/10/2025 ciprofloxacin hydrochloride Tablet, film coated 832.5 mg Anticipated Available Manufacturing 16/10/2025 midazolam Injection, solution 5 mg/mL Anticipated Available Manufacturing 16/10/2025 olsalazine sodium Capsule 250 mg Current Unavailable Manufacturing 16/10/2025 finasteride Tablet, film coated 1 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 lumefantrine~artemether Tablet, dispersible 120 mg~20 mg Discontinued Unavailable Commercial Changes / Commercial viability 16/10/2025 bisoprolol fumarate Tablet 5 mg Anticipated Available Manufacturing 16/10/2025 levetiracetam Tablet, film coated 500 mg Current Limited Availability Manufacturing 16/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 16/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Manufacturing 16/10/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 16/10/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 16/10/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 16/10/2025 sildenafil citrate Tablet, film coated 28.1 mg Current Unavailable Manufacturing 16/10/2025 ezetimibe~rosuvastatin calcium Tablet~Tablet, film coated 10 mg~41.583 mg Resolved Available Manufacturing 16/10/2025 oxytocin Injection, solution 5 IU/mL Resolved Available Unexpected increase in consumer demand 16/10/2025 oxytocin Injection, solution 10 IU/mL Resolved Available Manufacturing 16/10/2025 atorvastatin calcium trihydrate~ezetimibe Tablet, multilayer 10.9 mg~10 mg Resolved Available Manufacturing 16/10/2025 ezetimibe Tablet, uncoated 10 mg Current Unavailable Unexpected increase in consumer demand 16/10/2025 nicorandil Tablet, uncoated 10 mg Current Limited Availability Manufacturing 16/10/2025 tadalafil Tablet, film coated 5 mg Current Limited Availability Manufacturing 16/10/2025 latanoprost Eye Drops, solution .05 mg/mL Anticipated Available Manufacturing 16/10/2025 escitalopram oxalate Tablet, film coated 25.47 mg Current Limited Availability Manufacturing 16/10/2025 eplerenone Tablet, film coated 25 mg Resolved Available Manufacturing 16/10/2025 lacosamide Tablet, film coated 50 mg Anticipated Available Manufacturing 16/10/2025 ambrisentan Tablet, film coated 5 mg Anticipated Available Manufacturing 16/10/2025 nitrofurantoin Capsule, hard 100 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 methylphenidate hydrochloride Tablet, modified release 54 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 methylphenidate hydrochloride Tablet, modified release 27 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 olsalazine sodium Tablet, uncoated 500 mg Current Unavailable Manufacturing 16/10/2025 estradiol hemihydrate Drug delivery system, transdermal 3.09 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 hydrochlorothiazide~enalapril maleate Tablet, uncoated 6 mg~20 mg Anticipated Available Manufacturing 16/10/2025 valaciclovir hydrochloride Tablet, film coated 1112 mg Current Limited Availability Manufacturing 16/10/2025 estradiol hemihydrate Drug delivery system, transdermal 2.32 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 galantamine~galantamine hydrobromide Capsule, modified release 16 mg~20.51 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 16/10/2025 diclofenac sodium Tablet, enteric coated 50 mg Discontinued Unavailable Commercial Changes / Commercial viability 15/10/2025 propranolol hydrochloride Tablet, film coated 10 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 15/10/2025 propranolol hydrochloride Tablet, film coated 40 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 15/10/2025 alfentanil hydrochloride Injection, solution 1.0876 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 15/10/2025 pregabalin Capsule, hard 150 mg Resolved Available Manufacturing 15/10/2025 pregabalin Capsule, hard 75 mg Resolved Available Manufacturing 15/10/2025 dabigatran etexilate mesilate Capsule, hard 126.83 mg Resolved Available Manufacturing 15/10/2025 lurasidone hydrochloride Tablet, film coated 80 mg Current Unavailable Manufacturing 15/10/2025 rivaroxaban Tablet, film coated 15 mg Anticipated Available Manufacturing 15/10/2025 levothyroxine sodium Tablet 50 microgram Current Unavailable Unexpected increase in consumer demand 15/10/2025 metronidazole Tablet, film coated 400 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 15/10/2025 rifampicin Capsule, hard 300 mg Current Unavailable Manufacturing 15/10/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 15/10/2025 diclofenac sodium Tablet, enteric coated 25 mg Discontinued Unavailable Commercial Changes / Commercial viability 14/10/2025 valaciclovir hydrochloride Tablet, film coated 556.275 mg Resolved Available Manufacturing 14/10/2025 methylphenidate hydrochloride Capsule, modified release 10 mg Current Limited Availability Manufacturing 14/10/2025 ephedrine sulfate Injection, solution 30 mg/mL Anticipated Available Manufacturing 14/10/2025 montelukast sodium Tablet, chewable 5.2 mg Resolved Available Manufacturing 14/10/2025 primaquine phosphate Tablet, uncoated 13.2 mg Anticipated Available Manufacturing 14/10/2025 methylphenidate hydrochloride Capsule, modified release 60 mg Current Unavailable Manufacturing 14/10/2025 olmesartan medoxomil~hydrochlorothiazide Tablet 20 mg~12.5 mg Anticipated Available Manufacturing 14/10/2025 atenolol Tablet, film coated 50 mg Current Unavailable Manufacturing 14/10/2025 nebivolol hydrochloride Tablet 1.363 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 14/10/2025 metoprolol succinate Tablet, modified release 23.75 mg Resolved Available Manufacturing 14/10/2025 levothyroxine sodium Tablet 100 microgram Current Unavailable Unexpected increase in consumer demand 14/10/2025 methylphenidate hydrochloride Capsule, modified release 20 mg Current Limited Availability Manufacturing 14/10/2025 methylphenidate hydrochloride Capsule, modified release 30 mg Current Limited Availability Manufacturing 14/10/2025 methylphenidate hydrochloride Capsule, modified release 40 mg Current Unavailable Manufacturing 14/10/2025 phenytoin sodium Injection, solution 250 mg Anticipated Available Manufacturing 13/10/2025 lidocaine hydrochloride Injection, solution 20 mg/mL Resolved Available Manufacturing 13/10/2025 adrenaline (epinephrine) acid tartrate~lidocaine hydrochloride Injection, solution 9.1 microgram/mL~20 mg/mL Resolved Available Manufacturing 13/10/2025 venlafaxine hydrochloride Capsule, modified release 84.86 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 13/10/2025 ethinylestradiol~drospirenone Tablet 30 microgram~3 mg Current Limited Availability Manufacturing 13/10/2025 galantamine hydrobromide Capsule, modified release 10.252 mg Current Unavailable Manufacturing 13/10/2025 milrinone Injection, concentrated 10 mg Current Limited Availability Manufacturing 13/10/2025 irbesartan Tablet, film coated 150 mg Current Unavailable Manufacturing 13/10/2025 montelukast sodium Tablet, chewable 5.2 mg Current Unavailable Manufacturing 13/10/2025 potassium chloride Tablet, modified release 600 mg Resolved Available Manufacturing 13/10/2025 lacosamide Tablet, film coated 100 mg Resolved Available Manufacturing 13/10/2025 phenytoin sodium Injection, solution 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 13/10/2025 bromazepam Tablet, uncoated 6 mg Anticipated Available Transport / Logistic issues / Storage capacity issues 13/10/2025 cisatracurium besilate Injection, solution 2.68 mg/mL Resolved Available Manufacturing 13/10/2025 pramipexole dihydrochloride monohydrate Tablet, uncoated .25 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 13/10/2025 spironolactone Tablet, film coated 25 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 13/10/2025 - 2025.10.20
- 2025.10.20
New
October 17, 2025
- Elbasvir; Grazoprevir Tablet (Discontinuation)
October 16, 2025
- Pemetrexed Disodium Injection (Discontinuation)
- Vigabatrin Oral Solution (Discontinuation)
- Voriconazole Injection (Discontinuation)
Updated
October 17, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Dexamethasone Sodium Phosphate Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
October 16, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Azacitidine Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
October 15, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Bupivacaine Hydrochloride Injection (Currently in Shortage)
- Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Currently in Shortage)
- Dobutamine Hydrochloride Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Lorazepam Injection (Currently in Shortage)
- Meperidine Hydrochloride Injection (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Midazolam Hydrochloride Injection (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Penicillin G Benzathine Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- Sterile Water Injection (Currently in Shortage)
- Sufentanil Citrate Injection (Currently in Shortage)
- 2025.10.13
Active ingredients Message type Date of last message Type of reason AM designation Tinzaparin sodium Change notification 10.10.2025 Production problem innohep 4,500 Anti-Xa I.E. Solution for injection Carbamazepine Initial report 09.10.2025 Production problem Carbamazepine Aristo 600 mg prolonged-release tablets Carbamazepine Initial report 09.10.2025 Production problem Carbamazepine Aristo 300 mg prolonged-release tablets Ezetimibe; simvastatin Change notification 09.10.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/80 mg tablets Ezetimibe; simvastatin Change notification 09.10.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/40 mg tablets Ezetimibe; simvastatin Change notification 09.10.2025 Production problem EZETIMIB/SIMVA BASICS 10 mg/20 mg tablets Ezetimibe; simvastatin Change notification 09.10.2025 Production problem EZETIMIBE/SIMVA BASICS 10 mg/10 mg tablets Esomeprazole hemimagnesium Change notification 09.10.2025 Production problem ESOMEPRAZOLE BASICS 40 mg gastro-resistant hard capsules Esomeprazole hemimagnesium Change notification 09.10.2025 Production problem ESOMEPRAZOLE BASICS 20 mg gastro-resistant hard capsules Moxifloxacin hydrochloride (Ph.Eur.) ((with information on water content (1:x))) Initial report 09.10.2025 Other Moxifloxacin Holsten 400 mg film-coated tablets Leflunomide Initial report 09.10.2025 Other Leflunomide Bluefish 20 mg film-coated tablets Methylphenidate hydrochloride Change notification 09.10.2025 Other METHYLPHENIDATE 20 mg tablets Methylphenidate hydrochloride Change notification 09.10.2025 Other METHYLPHENIDATE 5 mg tablets Leflunomide Initial report 09.10.2025 Other Leflunomide Bluefish 10 mg film-coated tablets Potassium canrenoate Change notification 09.10.2025 Production problem Aldactone 10 ml Canrenoate Urapidil Initial report 09.10.2025 Production problem Urapidil Bluefish 90 mg hard capsules, delayed release Urapidil Initial report 09.10.2025 Production problem Urapidil Bluefish 30 mg hard capsules, delayed release Methylphenidate hydrochloride Change notification 09.10.2025 Other Methylphenidate-ratiopharm 40 mg hard capsules with modified release Primidone Change notification 09.10.2025 Production problem Mylepsinum Quetiapine fumarate (Ph.Eur.) Change notification 09.10.2025 Other Quetiapine AbZ 150 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 09.10.2025 Other Quetiapine-ratiopharm 300 mg prolonged-release tablets Risperidone Change notification 09.10.2025 Production problem Risperidone-ratiopharm 25 mg powder and solvent for the preparation of a depot injection suspension Risperidone Change notification 09.10.2025 Production problem Risperidone-ratiopharm 37.5 mg powder and solvent for the preparation of a depot injection suspension Risperidone Change notification 09.10.2025 Production problem Risperidone-ratiopharm 50 mg powder and solvent for the preparation of a depot injection suspension Pramipexole dihydrochloride monohydrate Change notification 09.10.2025 Other Pramipexole-ratiopharm 0.52 mg prolonged-release tablets Pramipexole dihydrochloride monohydrate Change notification 09.10.2025 Other Pramipexole-ratiopharm 0.26 mg prolonged-release tablets Carbamazepine Change notification 09.10.2025 Other Carbamazepine-ratiopharm 400 mg prolonged-release tablets Carbamazepine Change notification 09.10.2025 Other Carbamazepine-ratiopharm 200 mg prolonged-release tablets Ribavirin Change notification 09.10.2025 Other Ribavirin-ratiopharm 400 mg film-coated tablets Ribavirin Change notification 09.10.2025 Other Ribavirin-ratiopharm 200 mg film-coated tablets Salbutamol sulfate Initial report 09.10.2025 Other Sultanol metered-dose inhaler Aprepitant Change notification 09.10.2025 Production problem Aprepitant STADA 125 mg hard capsules Human insulin (with manufacturing details); isophane insulin suspension for injection (Ph.Eur.) Change notification 08.10.2025 Other Actraphane 30 FlexPen 100 IU/ml injection suspension in injector – OP(10x3ml) Isophane insulin suspension for injection (Ph.Eur.) Change notification 08.10.2025 Other Protaphane FlexPen 100 IU/ml injection suspension in injector – OP(10x3ml) Nitrendipine Change notification 08.10.2025 Other Nitrendipine AL 20 Aprepitant Change notification 08.10.2025 Other Aprepitant AL 125 mg hard capsules Oxazepam Change notification 08.10.2025 Other Oxazepam AL 10 Quetiapine fumarate (Ph.Eur.) Change notification 08.10.2025 Other Quetiapine AL 50 mg prolonged-release tablets Amoxicillin trihydrate Change notification 08.10.2025 Other Amoxicillin AL TS Doxepin hydrochloride (Ph.Eur.) Change notification 07.10.2025 Production problem Doxepin 25 Holsten Azithromycin dihydrate Change notification 07.10.2025 Other Azithromycin AL 250 mg film-coated tablets Lacosamide Initial report 07.10.2025 Production problem Lacosamide UCB 10 mg/ml syrup Aprepitant Change notification 07.10.2025 Production problem Aprepitant beta 80 mg hard capsules Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Production problem Quetiapine beta 50 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Production problem Quetiapine beta 300 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Production problem Quetiapine beta 200 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Production problem Quetiapine beta 150 mg prolonged-release tablets Atomoxetine hydrochloride Change notification 07.10.2025 Production problem Atomoxetine beta 80 mg hard capsules Aprepitant Change notification 07.10.2025 Production problem Aprepitant beta 125 mg and 80 mg hard capsules Quetiapine fumarate (Ph.Eur.) Change notification 07.10.2025 Other Seroquel Prolong 200 mg prolonged-release tablets Amlodipine besylate; Perindopril tert-butylamine Change notification 07.10.2025 Other Perindopril/amlodipine Denk 4 mg/5 mg tablets Amlodipine besylate; Perindopril tert-butylamine Change notification 07.10.2025 Other Perindopril/amlodipine Denk 4 mg/10 mg tablets Amlodipine besylate; Perindopril tert-butylamine Change notification 07.10.2025 Other Perindopril/Amlodipine Denk 8 mg/10 mg tablets Clopidogrel besylate Change notification 07.10.2025 Other Clopidogrel Denk 75 mg film-coated tablets Methylphenidate hydrochloride Change notification 07.10.2025 Other Methylphenidate AL 36 mg prolonged-release tablets Methylphenidate hydrochloride Change notification 07.10.2025 Other Methylphenidate AL 27 mg prolonged-release tablets Epirubicin hydrochloride Change notification 07.10.2025 Production problem Epirubicin Hikma 2 mg/ml concentrate for solution for infusion Trimipramine mesylate Change notification 06.10.2025 Other Trimipramine – 1 A Pharma 40 mg/ml oral drops, solution Tenofovir disoproxil Initial report 06.10.2025 Other Tenofovir disoproxil Viatris 245 mg film-coated tablets – OP30 Tenofovir disoproxil Change notification 06.10.2025 Other Tenofovir disoproxil Mylan 245 mg film-coated tablets – OP90(3×30) Imiquimod Change notification 06.10.2025 Production problem Aldara 5% cream – OP24 Dacarbazine citrate Change notification 06.10.2025 Other Dacarbazine Lipomed 500 mg powder for solution for infusion Prednisolone acetate Change notification 06.10.2025 Production problem Prednifluid 10 mg/ml eye drop suspension Sevelamer Change notification 06.10.2025 Other Renagel 800 mg film-coated tablets – OP(1×180) Methylphenidate hydrochloride Change notification 06.10.2025 Other Methylphenidate hydrochloride-neuraxpharm 27 mg prolonged-release tablets Phenylephrine hydrochloride Change notification 06.10.2025 Production problem Neosynephrine-POS 10% Gentamicin sulfate Change notification 06.10.2025 Production problem Gentamicin-POS Beclometasone dipropionate (Ph.Eur.) Change notification 06.10.2025 Other Beclorhinol aquosum 50 micrograms - 2025.10.13
Active ingredients Statut Update Specialty betamethasone (dipropionate), betamethasone (sodium phosphate) Supply tension 09/10/2025 Diprostene, suspension for injection in pre-filled syringe pancreas powder Supply tension 08/10/2025 Eurobiol 40 000 U, gastroresistant capsule liothyronine sodium Supply tension 07/10/2025 Cynomel 0.025 mg, scored tablet furosemide Marketing discontinuation 06/10/2025 Lasilix Retard 60 mg, capsule peginterferon alfa-2a Return to availability 06/10/2025 Pegasys 90 micrograms, 135 micrograms and 180 micrograms solution for injection in prefilled syringes - 2025.10.13
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated tramadol hydrochloride Capsule 50 mg Resolved Available Manufacturing 10/10/2025 topiramate Tablet, film coated 50 mg Anticipated Available Manufacturing 10/10/2025 ciprofloxacin hydrochloride Tablet, film coated 832.5 mg Anticipated Available Manufacturing 10/10/2025 tetrabenazine Tablet, uncoated 25 mg Resolved Available Manufacturing 10/10/2025 venlafaxine hydrochloride Capsule, modified release 169.71 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 10/10/2025 fosaprepitant dimeglumine Injection, powder for 257.6 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 10/10/2025 temozolomide Capsule, hard 5 mg Current Limited Availability Manufacturing 10/10/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 10/10/2025 galantamine hydrobromide Capsule, modified release 30.756 mg Current Unavailable Manufacturing 10/10/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 10/10/2025 raloxifene hydrochloride Tablet, film coated 60 mg Current Unavailable Manufacturing 10/10/2025 quetiapine fumarate Tablet, film coated 115.12 mg Anticipated Available Commercial Changes / Commercial viability 10/10/2025 quetiapine fumarate Tablet, film coated 345.36 mg Anticipated Available Commercial Changes / Commercial viability 10/10/2025 cisatracurium besilate Injection, solution 7.04 mg Current Limited Availability Manufacturing 10/10/2025 mebeverine hydrochloride Tablet, film coated 135 mg Current Unavailable Manufacturing 10/10/2025 ropinirole hydrochloride Tablet, film coated .285 mg Current Unavailable Manufacturing 10/10/2025 lacosamide Tablet, film coated 150 mg Current Limited Availability Manufacturing 10/10/2025 Trastuzumab Injection, powder for 156 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 10/10/2025 teriflunomide Tablet, film coated 14 mg Current Limited Availability Manufacturing 10/10/2025 rivaroxaban Tablet, film coated 10 mg Anticipated Available Manufacturing 10/10/2025 valaciclovir hydrochloride Tablet, film coated 1112 mg Current Limited Availability Manufacturing 10/10/2025 phenoxymethylpenicillin potassium Oral Liquid, powder for 28.284 mg/mL Current Unavailable Manufacturing 9/10/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Limited Availability Manufacturing 9/10/2025 chloramphenicol Eye Drops 5 mg/mL Resolved Available Manufacturing 9/10/2025 lansoprazole Tablet, orally disintegrating 15 mg Current Unavailable Manufacturing 9/10/2025 desvenlafaxine Tablet, modified release 100 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 9/10/2025 desvenlafaxine Tablet, modified release 50 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 9/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Unexpected increase in consumer demand 9/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Unexpected increase in consumer demand 9/10/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 9/10/2025 hydrocortisone Tablet, uncoated 4 mg Anticipated Available Manufacturing 9/10/2025 ezetimibe~simvastatin Tablet 10 mg~40 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 9/10/2025 fingolimod hydrochloride Capsule 560 microgram Anticipated Available Manufacturing 9/10/2025 estradiol Drug delivery system, transdermal .39 mg Current Unavailable Manufacturing 9/10/2025 estradiol Drug delivery system, transdermal .78 mg Current Unavailable Manufacturing 9/10/2025 estradiol Drug delivery system, transdermal 1.17 mg Current Unavailable Manufacturing 9/10/2025 estradiol Drug delivery system, transdermal 1.56 mg Current Unavailable Manufacturing 9/10/2025 lenalidomide Capsule 5 mg Current Limited Availability Manufacturing 9/10/2025 bleomycin sulfate Injection, powder for 15000 IU Anticipated Available Manufacturing 9/10/2025 doxorubicin hydrochloride Injection, concentrated 20 mg Resolved Available Manufacturing 9/10/2025 methylphenidate hydrochloride Tablet, modified release 18 mg Current Limited Availability Manufacturing 9/10/2025 methylphenidate hydrochloride Tablet, modified release 36 mg Current Limited Availability Manufacturing 9/10/2025 tranexamic acid Tablet, film coated 500 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 8/10/2025 galantamine hydrobromide Capsule, modified release 30.768 mg Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 8/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 8/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 8/10/2025 valsartan~hydrochlorothiazide Tablet, film coated 320 mg~25 mg Resolved Available Manufacturing 8/10/2025 temozolomide Capsule, hard 20 mg Anticipated Available Manufacturing 8/10/2025 escitalopram oxalate Tablet, film coated 25.548 mg Anticipated Available Manufacturing 8/10/2025 lansoprazole Tablet, orally disintegrating 30 mg Current Unavailable Manufacturing 8/10/2025 anastrozole Tablet, film coated 1 mg Current Limited Availability Manufacturing 8/10/2025 clonidine hydrochloride Tablet 100 microgram Resolved Available Manufacturing 8/10/2025 hydrochlorothiazide~irbesartan Tablet, film coated 12.5 mg~150 mg Current Unavailable Manufacturing 8/10/2025 hydrochlorothiazide~irbesartan Tablet, film coated 25 mg~300 mg Current Unavailable Manufacturing 8/10/2025 metformin hydrochloride Tablet, film coated 1000 mg Current Unavailable Unexpected increase in consumer demand 8/10/2025 Mecasermin Injection, solution 10 mg/mL Resolved Available Unexpected increase in consumer demand 8/10/2025 erlotinib hydrochloride Tablet, film coated 27.32 mg Current Unavailable Unexpected increase in consumer demand 8/10/2025 spironolactone Tablet, uncoated 25 mg Resolved Available Manufacturing 8/10/2025 bortezomib Injection, solution 3.5 mg Resolved Available Manufacturing 8/10/2025 paracetamol Tablet, modified release 665 mg Resolved Available Transport / Logistic issues / Storage capacity issues 8/10/2025 naproxen Tablet, uncoated 250 mg Resolved Available Manufacturing 8/10/2025 tranexamic acid Tablet, film coated 500 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 8/10/2025 trandolapril Capsule, hard 2 mg Resolved Available Manufacturing 8/10/2025 rifampicin Capsule, hard 300 mg Current Unavailable Manufacturing 8/10/2025 clindamycin phosphate Cream 22.8 mg/g Resolved Available Transport / Logistic issues / Storage capacity issues 8/10/2025 paclitaxel Injection, concentrated 6 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 8/10/2025 labetalol hydrochloride Tablet, film coated 100 mg Current Limited Availability Manufacturing 8/10/2025 dosulepin hydrochloride Tablet, film coated 75 mg Current Limited Availability Manufacturing 8/10/2025 metformin hydrochloride Tablet, film coated 1000 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 8/10/2025 acetylcysteine Injection, concentrated 2 g Current Limited Availability Manufacturing 7/10/2025 topiramate Tablet, film coated 25 mg Current Unavailable Manufacturing 7/10/2025 ciprofloxacin hydrochloride Tablet, film coated 277.5 mg Current Unavailable Manufacturing 7/10/2025 acetazolamide sodium Injection, powder for 549.5 mg Current Unavailable Manufacturing 7/10/2025 lamotrigine Tablet, chewable 50 mg Anticipated Available Manufacturing 7/10/2025 lamotrigine Tablet, chewable 100 mg Current Unavailable Manufacturing 7/10/2025 olanzapine Tablet, film coated 5 mg Current Unavailable Manufacturing 7/10/2025 methylphenidate hydrochloride Capsule, modified release 10 mg Current Limited Availability Manufacturing 7/10/2025 levetiracetam Tablet, film coated 500 mg Current Limited Availability Manufacturing 7/10/2025 sildenafil citrate Tablet, film coated 140.45 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 7/10/2025 sulfamethoxazole~trimethoprim Tablet, uncoated 800 mg~160 mg Resolved Available Manufacturing 7/10/2025 exemestane Tablet, sugar coated 25 mg Anticipated Available Manufacturing 7/10/2025 olanzapine Tablet, orally disintegrating 10 mg Anticipated Available Manufacturing 7/10/2025 olanzapine Tablet, orally disintegrating 5 mg Anticipated Available Manufacturing 7/10/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Current Unavailable Manufacturing 7/10/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Anticipated Available Manufacturing 7/10/2025 galantamine hydrobromide Capsule, modified release 10.252 mg Current Unavailable Manufacturing 7/10/2025 galantamine hydrobromide Capsule, modified release 30.756 mg Current Unavailable Manufacturing 7/10/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 7/10/2025 indapamide hemihydrate Tablet, sugar coated 2.5 mg Current Limited Availability Manufacturing 7/10/2025 montelukast sodium Tablet, chewable 4.16 mg Current Unavailable Manufacturing 7/10/2025 isotretinoin Capsule, soft 10 mg Current Unavailable Manufacturing 7/10/2025 isotretinoin Capsule, soft 20 mg Current Unavailable Manufacturing 7/10/2025 enalapril maleate Tablet 5 mg Anticipated Available Manufacturing 7/10/2025 phenobarbital Tablet, uncoated 30 mg Anticipated Available Manufacturing 7/10/2025 metformin hydrochloride Tablet, film coated 1000 mg Current Unavailable Manufacturing 7/10/2025 citalopram hydrobromide Tablet, film coated 49.98 mg Resolved Available Manufacturing 7/10/2025 ezetimibe Tablet, uncoated 10 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 7/10/2025 tranexamic acid Tablet, film coated 500 mg Current Limited Availability Manufacturing 7/10/2025 ivabradine hydrochloride Tablet, film coated 8.085 mg Resolved Available Manufacturing 7/10/2025 teriflunomide Tablet, film coated 14 mg Current Unavailable Manufacturing 7/10/2025 pregabalin Capsule, hard 300 mg Anticipated Available Manufacturing 7/10/2025 oseltamivir phosphate Capsule, hard 98.524 mg Current Limited Availability Manufacturing 7/10/2025 sitagliptin hydrochloride monohydrate~metformin hydrochloride Tablet, modified release 56.685 mg~1000 mg Anticipated Available Manufacturing 7/10/2025 Teriparatide Injection, solution .25 mg/mL Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 7/10/2025 Teriparatide Injection, solution 250 microgram/mL Current Unavailable Manufacturing 7/10/2025 minocycline hydrochloride dihydrate Tablet, film coated 54 mg Resolved Available Manufacturing 7/10/2025 olanzapine Injection, powder for 10 mg Resolved Available Unexpected increase in consumer demand 7/10/2025 ciprofloxacin hydrochloride Tablet, film coated 873.32 mg Current Limited Availability Manufacturing 7/10/2025 methylphenidate hydrochloride Capsule, modified release 30 mg Current Limited Availability Manufacturing 7/10/2025 amoxicillin trihydrate Oral Liquid, powder for 28.7 mg/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 6/10/2025 - 2025.10.13
Generic Name Shortage Status Revision Date Rocuronium Injection Current Shortages 9-Oct-25 Budesonide Suspension for Inhalation Current Shortages 7-Oct-25 Difluprednate Ophthalmic Emulsion Current Shortages 7-Oct-25 Magnesium Sulfate Injection Current Shortages 7-Oct-25 Oseltamivir Oral Suspension and Capsules Current Shortages 7-Oct-25 Remifentanil Injection Current Shortages 7-Oct-25 Triamcinolone Acetonide Injectable Suspension Current Shortages 7-Oct-25 Bupivacaine Injection Current Shortages 6-Oct-25 Dulaglutide Injection Current Shortages 6-Oct-25 Leucovorin Calcium Injection Current Shortages 6-Oct-25 Lidocaine Hydrochloride Oral Topical Solution (Viscous) 2% Current Shortages 6-Oct-25 Mometasone Furoate and Formoterol Fumarate Inhalation Aerosol Current Shortages 6-Oct-25 Oxycodone Hydrochloride and Acetaminophen Tablets Current Shortages 6-Oct-25 Paricalcitol Capsules Current Shortages 6-Oct-25 Sodium Bicarbonate Injection Current Shortages 6-Oct-25 Vancomycin Hydrochloride Injection Current Shortages 6-Oct-25 - 2025.10.13
New
October 10, 2025
- Pemetrexed Disodium Injection (Discontinuation)
October 09, 2025
- Adalimumab-afzb Injection (Discontinuation)
- Hydrocortisone Sodium Succinate Injection (Currently in Shortage)
- Omeprazole Delayed Release Capsule (Discontinuation)
October 07, 2025
- Cobicistat Tablet (Discontinuation)
- Paricalcitol Capsule (Discontinuation)
Updatede
October 09, 2025
- Dexmedetomidine Hydrochloride Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
October 08, 2025
- Azacitidine Injection (Currently in Shortage)
- Bupivacaine Hydrochloride Injection (Currently in Shortage)
- Carboplatin Injection (Currently in Shortage)
- Dexamethasone Sodium Phosphate Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Penicillin G Benzathine Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Ropivacaine Hydrochloride Injection (Currently in Shortage)
October 06, 2025
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
- 2025.10.05
Active ingredients Message type Date of last message Type of reason AM designation Enalapril maleate; hydrochlorothiazide Change notification 03.10.2025 Production problem Renacor Methyldopa (Ph.Eur.) Initial report 03.10.2025 Production problem Presinol 500 Cefaclor monohydrate Change notification 02.10.2025 Other Cefaclor 125 TS – 1 A Pharma Cefpodoxime proxetil Initial report 02.10.2025 Other Cefpodoxime – 1 A Pharma 40 mg/5 ml powder for oral suspension Morphine hemisulfate 2.5 hydrate Initial report 02.10.2025 Production problem Substitol 30 mg hard capsules, delayed release Oxycodone hydrochloride (Ph.Eur.) Change notification 02.10.2025 Production problem Oxygesic 5 mg Rifampicin Change notification 02.10.2025 Other EREMFAT 150 mg Oxycodone hydrochloride Change notification 02.10.2025 Other OXYGESIC 10 mg Pyrazinamide Initial report 02.10.2025 Production problem Pyrafat 500 mg Azithromycin dihydrate Change notification 02.10.2025 Other Azithromycin AL 250 mg film-coated tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 200 mg prolonged-release tablets Calcium acetate hydrate (with information on water content (1:x)) Initial report 01.10.2025 Production problem Calcium acetate-Nefro 950mg Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 150 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 50 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 400 mg prolonged-release tablets Quetiapine fumarate (Ph.Eur.) Change notification 01.10.2025 Production problem Quetiapine Heumann retard 300 mg prolonged-release tablets Vinorelbine tartrate Initial report 01.10.2025 Production problem Bendarelbin 10 mg/ml concentrate for solution for infusion Sodium perchlorate 1 H<2>O Change notification 30.09.2025 Other Irenat drops Galantamine hydrobromide Change notification 30.09.2025 Production problem Galantamine Heumann 8 mg hard capsules, delayed release Galantamine hydrobromide Change notification 30.09.2025 Production problem Galantamine Heumann 16 mg hard capsules, delayed release Galantamine hydrobromide Change notification 30.09.2025 Production problem Galantamine Heumann 24 mg hard capsules, delayed release Clomethiazole hemidisilate Change notification 30.09.2025 Other Distraneurin mixture Pramipexole dihydrochloride monohydrate Change notification 30.09.2025 Other Pramipexole HEXAL 0.26 mg prolonged-release tablets Pramipexole dihydrochloride monohydrate Change notification 30.09.2025 Other Pramipexole HEXAL 0.52 mg prolonged-release tablets Phenoxymethylpenicillin potassium Change notification 30.09.2025 Other Pen Mega – 1 A Pharma Rifampicin sodium Initial report 30.09.2025 Other Eremfat i.v. 600mg Ascorbic acid; biotin; cholecalciferol; cyanocobalamin; dexpanthenol; folic acid hydrate ((with information on water content (1:x))); Nicotinamide; pyridoxine hydrochloride; retinol palmitate; riboflavin phosphate sodium; thiamine hydrochloride; all-rac-phytomenadione; all-rac-alpha-tocopherol Initial report 30.09.2025 Production problem Viant powder for solution for infusion Tropicamide Change notification 30.09.2025 Production problem Mydriaticum Stulln UD Ipratropium bromide (Ph.Eur.); salbutamol sulfate Change notification 30.09.2025 Production problem COMBIPRASAL 0.5 mg / 2.5 mg solution for nebulizer Ipratropium bromide Change notification 30.09.2025 Production problem Ipratropium bromide 250 micrograms / 1 ml Stulln Paliperidone palmitate Change notification 30.09.2025 Other Paliperidone AL 25 mg depot injection suspension in a pre-filled syringe Methylphenidate hydrochloride Change notification 30.09.2025 Other Methylphenidate AL 36 mg prolonged-release tablets Paliperidone palmitate Change notification 30.09.2025 Other Paliperidone AL 50 mg Depot injection suspension in a pre-filled syringe Beclomethasone dipropionate (Ph.Eur.) Change notification 29.09.2025 Other Beclorhinol aquosum 50 micrograms Insulin glargine Change notification 29.09.2025 Other Semglee 100 units/ml injection solution in pre-filled pen – OP(5x3ml) Insulin glargine Change notification 29.09.2025 Other Semglee Methylphenidate hydrochloride Initial report 29.09.2025 Other Equasym Retard 40 mg hard capsules with modified release - 2025.10.05
Active ingredients Statut Update Specialty tranexamic acid Return to availability 03/10/2025 Exacyl 500 mg, film-coated tablet chlorpromazine (hydrochloride) Out of stock 03/10/2025 Largactil 100 mg, scored film-coated tablet praziquantel Out of stock 02/10/2025 Biltricide 600 mg, film-coated quadrisectible tablet fluorouracil Out of stock 02/10/2025 Fluorouracil Pfizer 50 mg/ml, dilutable solution for infusion20 ml and 100 ml bottle atropine (sulfate) Supply tension 02/10/2025 Atropine 0.3%, eye drops Immunoglobulin normal human (IgG) Supply tension 01/10/2025 Immunoglobulin normal human IV and SC (based on) propofol Out of stock 29/09/2025 Diprivan 10 mg/mL, emulsion for injection in pre-filled syringe propofol Supply tension 29/09/2025 Diprivan 20 mg/mL, emulsion for injection in pre-filled syringe - 2025.10.05
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated trandolapril~verapamil hydrochloride Tablet, film coated 4 mg~240 mg Current Limited Availability Manufacturing 3/10/2025 acetylcholine chloride Solution, powder for irrigation 10 mg/mL Resolved Available Manufacturing 3/10/2025 ramipril Tablet, uncoated 1.25 mg Anticipated Available Manufacturing 3/10/2025 Equine antithymocyte immunoglobulin Injection, solution 50 mg/mL Resolved Available Manufacturing 3/10/2025 bromocriptine mesilate Tablet, uncoated 2.87 mg Resolved Available Manufacturing 3/10/2025 buprenorphine hydrochloride Injection, solution 324 microgram/mL Current Unavailable Manufacturing 3/10/2025 iopromide Injection, solution 498.72 mg/mL Current Unavailable Manufacturing 3/10/2025 silver sulfadiazine Cream 10 mg/g Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 3/10/2025 silver sulfadiazine Cream 10 mg/g Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 3/10/2025 risperidone Tablet, film coated 2 mg Anticipated Available Manufacturing 3/10/2025 pioglitazone hydrochloride Tablet 49.9 mg Anticipated Available Manufacturing 3/10/2025 hydrocortisone sodium succinate Injection, powder for 134 mg Anticipated Available Manufacturing 3/10/2025 pramipexole dihydrochloride monohydrate Tablet .125 mg Current Unavailable Manufacturing 3/10/2025 pramipexole dihydrochloride monohydrate Tablet .25 mg Current Unavailable Manufacturing 3/10/2025 pramipexole dihydrochloride monohydrate Tablet 1 mg Anticipated Available Manufacturing 3/10/2025 trandolapril Capsule, hard .5 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 trandolapril Capsule, hard 1 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 trandolapril Capsule, hard 2 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 trandolapril Capsule, hard 4 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 metoprolol succinate Tablet, modified release 95 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 metoprolol succinate Tablet, modified release 47.5 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 metoprolol succinate Tablet, modified release 190 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 metoprolol succinate Tablet, modified release 23.75 mg Discontinued Unavailable Commercial Changes / Commercial viability 3/10/2025 paclitaxel Injection, concentrated 300 mg Current Unavailable Manufacturing 3/10/2025 adrenaline (epinephrine) acid tartrate~articaine hydrochloride Injection, solution 18.2 microgram/mL~40 mg/mL Resolved Available Transport / Logistic issues / Storage capacity issues 3/10/2025 citalopram hydrobromide Tablet, film coated 12.495 mg Current Limited Availability Manufacturing 3/10/2025 bimatoprost Eye Drops .3 mg/mL Current Unavailable Manufacturing 3/10/2025 methylphenidate hydrochloride Capsule, modified release 60 mg Current Unavailable Manufacturing 3/10/2025 hydrochlorothiazide~irbesartan Tablet, film coated 12.5 mg~300 mg Current Unavailable Manufacturing 3/10/2025 nizatidine Capsule, hard 150 mg Current Unavailable Manufacturing 3/10/2025 ambrisentan Tablet, film coated 10 mg Anticipated Available Manufacturing 3/10/2025 mefenamic acid Capsule, hard 250 mg Current Unavailable Manufacturing 3/10/2025 dabigatran etexilate mesilate Capsule, hard 126.83 mg Current Limited Availability Manufacturing 3/10/2025 posaconazole Tablet, modified release 100 mg Resolved Available Manufacturing 3/10/2025 sacubitril~valsartan Tablet, film coated 48.6 mg~51.4 mg Resolved Available Manufacturing 3/10/2025 valsartan~sacubitril Tablet, film coated 102.8 mg~97.2 mg Resolved Available Manufacturing 3/10/2025 carboplatin Injection, solution 10 mg/mL Resolved Available Unexpected increase in demand due to other sponsors unable to supply 3/10/2025 iotroxate meglumine Injection, solution 105.46 mg/mL Current Unavailable Transport / Logistic issues / Storage capacity issues 3/10/2025 methylphenidate hydrochloride Capsule, modified release 20 mg Current Limited Availability Manufacturing 3/10/2025 methylphenidate hydrochloride Capsule, modified release 40 mg Current Unavailable Manufacturing 3/10/2025 Measles virus~Rubella virus~Mumps virus Injection, powder for 1000 CCID50~1000 CCID50~5000 CCID50 Resolved Available Unexpected increase in consumer demand 3/10/2025 prazosin hydrochloride Tablet, uncoated 1.095 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 2/10/2025 prazosin hydrochloride Tablet, uncoated 5.476 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 2/10/2025 metformin hydrochloride Tablet, film coated 500 mg Current Unavailable Manufacturing 2/10/2025 valsartan~hydrochlorothiazide Tablet, film coated 320 mg~25 mg Current Limited Availability Manufacturing 2/10/2025 risperidone Tablet, film coated .5 mg Current Unavailable Manufacturing 2/10/2025 entecavir Tablet, film coated .5 mg Current Unavailable Manufacturing 2/10/2025 entecavir Tablet, film coated 1 mg Anticipated Available Manufacturing 2/10/2025 Trastuzumab Injection, solution 600 mg Resolved Available Manufacturing 2/10/2025 rosuvastatin calcium Tablet, film coated 20.84 mg Current Limited Availability Unexpected increase in consumer demand 2/10/2025 azacitidine Injection, powder for 100 mg Resolved Available Manufacturing 2/10/2025 tranexamic acid Tablet, film coated 500 mg Current Unavailable Manufacturing 2/10/2025 ambrisentan Tablet, film coated 5 mg Anticipated Available Manufacturing 2/10/2025 deferasirox Tablet, film coated 90 mg Current Limited Availability Manufacturing 2/10/2025 deferasirox Tablet, film coated 360 mg Current Limited Availability Manufacturing 2/10/2025 metoprolol succinate Tablet, modified release 23.75 mg Current Limited Availability Manufacturing 2/10/2025 sitagliptin hydrochloride monohydrate~metformin hydrochloride Tablet, film coated 56.69 mg~1000 mg Resolved Available Manufacturing 2/10/2025 quinagolide hydrochloride Tablet, uncoated .0819 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 2/10/2025 prazosin hydrochloride Tablet, uncoated 1.1 mg Current Unavailable Manufacturing 2/10/2025 sertraline hydrochloride Tablet, film coated 56 mg Current Unavailable Manufacturing 2/10/2025 sertraline hydrochloride Tablet, film coated 112 mg Current Limited Availability Manufacturing 2/10/2025 mirtazapine Tablet, film coated 30 mg Resolved Available Manufacturing 2/10/2025 live varicella vaccine Injection, powder for 2700 PFU/mL Current Unavailable Unexpected increase in demand due to other sponsors unable to supply 1/10/2025 sertraline hydrochloride Tablet, film coated 55.96 mg Current Unavailable Manufacturing 1/10/2025 risperidone Tablet 1 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 1/10/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Current Limited Availability Manufacturing 1/10/2025 atorvastatin calcium trihydrate Tablet, film coated 21.69 mg Current Limited Availability Manufacturing 1/10/2025 atorvastatin calcium trihydrate Tablet, film coated 43.38 mg Current Unavailable Manufacturing 1/10/2025 ceftaroline fosamil Injection, powder for 600 mg Resolved Available Manufacturing 1/10/2025 clopidogrel hydrogen sulfate~aspirin Tablet 97.87 mg~100 mg Resolved Available Manufacturing 1/10/2025 live varicella vaccine Injection, powder for 4000 PFU/mL Current Only available under NIP or government programs Unexpected increase in consumer demand 1/10/2025 mesalazine Tablet, enteric coated 800 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 1/10/2025 Rabies virus Injection, powder for 2.5 IU Current Emergency Supply Only Unexpected increase in consumer demand 1/10/2025 teriflunomide Tablet, film coated 14 mg Current Limited Availability Manufacturing 1/10/2025 Mecasermin Injection, solution 10 mg/mL Current Limited Availability Unexpected increase in consumer demand 1/10/2025 estradiol~estradiol~norethisterone acetate Drug delivery system, transdermal .78 mg~.62 mg~2.7 mg Resolved Available Manufacturing 1/10/2025 GluureaLys(ahx)hbedCC Injection, powder for 25 microgram Current Unavailable Manufacturing 1/10/2025 tranexamic acid Tablet, film coated 500 mg Anticipated Available Unexpected increase in demand due to other sponsors unable to supply 1/10/2025 rifampicin Capsule, hard 150 mg Current Limited Availability Manufacturing 1/10/2025 lidocaine hydrochloride monohydrate Injection, solution 20 mg/mL Resolved Available Manufacturing 1/10/2025 prazosin hydrochloride Tablet, uncoated 2.2 mg Current Unavailable Manufacturing 1/10/2025 prazosin hydrochloride Tablet, uncoated 5.5 mg Current Unavailable Manufacturing 1/10/2025 primidone Tablet, uncoated 250 mg Current Limited Availability Manufacturing 30/09/2025 lidocaine hydrochloride Gel 20 mg/g Current Limited Availability Manufacturing 30/09/2025 pantoprazole sodium sesquihydrate Tablet, enteric coated 45.4 mg Current Limited Availability Unexpected increase in consumer demand 30/09/2025 midazolam Injection, solution 50 mg Resolved Available Manufacturing 30/09/2025 midazolam Injection, solution 50 mg Current Limited Availability Manufacturing 30/09/2025 docetaxel Injection, concentrated 80 mg Resolved Available Manufacturing 30/09/2025 rosuvastatin calcium Tablet, film coated 41.68 mg Current Limited Availability Manufacturing 30/09/2025 rosuvastatin calcium Tablet, film coated 10.42 mg Current Unavailable Manufacturing 30/09/2025 pregabalin Capsule, hard 75 mg Current Limited Availability Manufacturing 30/09/2025 atorvastatin calcium trihydrate Tablet, film coated 86.76 mg Current Unavailable Manufacturing 30/09/2025 dabigatran etexilate mesilate Capsule, hard 172.95 mg Current Unavailable Manufacturing 30/09/2025 oseltamivir phosphate Capsule, hard 98.524 mg Current Limited Availability Manufacturing 30/09/2025 cabazitaxel Injection, concentrated 60 mg Current Limited Availability Manufacturing 30/09/2025 fentanyl citrate Injection, solution 785 microgram Current Unavailable Manufacturing 30/09/2025 ropivacaine hydrochloride Injection, solution 10 mg/mL Current Unavailable Manufacturing 30/09/2025 gefitinib Tablet, film coated 250 mg Discontinued Unavailable Commercial Changes / Commercial viability 30/09/2025 betamethasone valerate Cream 1.21 mg/g Resolved Available Manufacturing 29/09/2025 fludarabine phosphate Injection, powder for 50 mg Current Limited Availability Manufacturing 29/09/2025 finasteride Tablet, film coated 1 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 29/09/2025 sulfamethoxazole~trimethoprim Tablet, uncoated 800 mg~160 mg Current Limited Availability Manufacturing 29/09/2025 clopidogrel hydrogen sulfate Tablet, film coated 97.875 mg Current Limited Availability Unexpected increase in consumer demand 29/09/2025 chloramphenicol Eye Drops 5 mg/mL Current Unavailable Manufacturing 29/09/2025 phenobarbital Tablet, uncoated 30 mg Anticipated Available Manufacturing 29/09/2025 quetiapine fumarate Tablet, modified release 57.5 mg Anticipated Available Unexpected increase in consumer demand 29/09/2025 irbesartan Tablet, film coated 75 mg Current Limited Availability Manufacturing 29/09/2025 ivabradine hydrochloride Tablet, film coated 5.39 mg Resolved Available Manufacturing 29/09/2025 dimethyl fumarate Capsule, enteric 120 mg Resolved Available Manufacturing 29/09/2025 lurasidone hydrochloride Tablet, film coated 40 mg Current Unavailable Manufacturing 29/09/2025 lurasidone hydrochloride Tablet, film coated 80 mg Current Unavailable Manufacturing 29/09/2025 potassium chloride Tablet, modified release 600 mg Current Limited Availability Manufacturing 29/09/2025 spironolactone Tablet, uncoated 25 mg Current Limited Availability Manufacturing 29/09/2025 tetrabenazine Tablet, uncoated 25 mg Current Unavailable Manufacturing 29/09/2025 lidocaine hydrochloride Injection, solution 10 mg/mL Current Unavailable Manufacturing 29/09/2025 cisatracurium besilate Injection, solution 2.68 mg/mL Current Unavailable Manufacturing 29/09/2025 olanzapine Tablet, film coated 5 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 29/09/2025 olanzapine Wafer 5 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 29/09/2025 - 2025.10.05
- 2025.10.05
New
October 01, 2025
- Hydrochlorothiazide; Quinapril Hydrochloride Tablet (Discontinuation)
- Quinapril Hydrochloride Tablet (Discontinuation)
September 30, 2025
- Oseltamivir Phosphate Capsule (Discontinuation)
September 29, 2025
- Fondaparinux Sodium Injection (Discontinuation)
- Tafamidis Meglumine Capsule (Discontinuation)
- Triazolam Tablet (Discontinuation)
Updated
October 03, 2025
- Lactated Ringers Injection (Resolved)
- Lactated Ringers Injection (Discontinuation)
October 02, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Azacitidine Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methylphenidate Film, Extended Release (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
October 01, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Currently in Shortage)
- Epinephrine Bitartrate, Lidocaine Hydrochloride Injection (Currently in Shortage)
- Fentanyl Citrate Injection (Currently in Shortage)
- Heparin Sodium Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Naltrexone Hydrochloride Tablet (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
September 29, 2025
- Desmopressin Acetate Spray (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Metronidazole Injection (Currently in Shortage)